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Real world study of safety and efficacy of lorlatinib as second line and beyond in ALK-rearranged advanced non-small cell lung cancer patients in India – a multicentre chart review study (ROSELAND) 印度ALK重组晚期非小细胞肺癌患者二线及二线以上使用lorlatinib的安全性和有效性的真实世界研究--多中心病历回顾研究（ROSELAND）
ecancermedicalscience Pub Date : 2024-02-13 DOI: 10.3332/ecancer.2024.1667
B. Biswas, Nikhil S Ghadyalpatil, Shekar Patil, Amol Patel, S. Ganguly, Anvesh Rathore, B. Guleria, Cpalli Firdouse Tarannum, Joydeep Ghosh, Mary Sravani Kondapally, Ravi Thippeswamy, Shashidhara Haragadde Poppa Reddy, Somnath Roy
{"title":"Real world study of safety and efficacy of lorlatinib as second line and beyond in ALK-rearranged advanced non-small cell lung cancer patients in India – a multicentre chart review study (ROSELAND)","authors":"B. Biswas, Nikhil S Ghadyalpatil, Shekar Patil, Amol Patel, S. Ganguly, Anvesh Rathore, B. Guleria, Cpalli Firdouse Tarannum, Joydeep Ghosh, Mary Sravani Kondapally, Ravi Thippeswamy, Shashidhara Haragadde Poppa Reddy, Somnath Roy","doi":"10.3332/ecancer.2024.1667","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1667","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"131 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139839915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding of disease status, prognosis and estimated cost of treatment among cancer patients: experience from a tertiary cancer centre in Nepal 癌症患者对疾病状况、预后和治疗费用估算的了解：尼泊尔一家三级癌症中心的经验
ecancermedicalscience Pub Date : 2024-02-13 DOI: 10.3332/ecancer.2024.1668
S. Baral, S. Silwal, Deep Lamichhane, Abish Adhikari, Nancy Bhattarai
{"title":"Understanding of disease status, prognosis and estimated cost of treatment among cancer patients: experience from a tertiary cancer centre in Nepal","authors":"S. Baral, S. Silwal, Deep Lamichhane, Abish Adhikari, Nancy Bhattarai","doi":"10.3332/ecancer.2024.1668","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1668","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"472 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139841360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
oss of CDX2 and high COX2 (PTGS2) expression in metastatic colorectal cancer CDX2 和 COX2（PTGS2）高表达在转移性结直肠癌中的影响
ecancermedicalscience Pub Date : 2024-02-08 DOI: 10.3332/ecancer.2024.1666
Álvaro M C Caldas, Warley A Nunes, Rodrigo Taboada, Marcelle G Cesca, Janaína N Germano, Rachel P. Riechelmann
{"title":"oss of CDX2 and high COX2 (PTGS2) expression in metastatic colorectal cancer","authors":"Álvaro M C Caldas, Warley A Nunes, Rodrigo Taboada, Marcelle G Cesca, Janaína N Germano, Rachel P. Riechelmann","doi":"10.3332/ecancer.2024.1666","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1666","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139793395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
oss of CDX2 and high COX2 (PTGS2) expression in metastatic colorectal cancer CDX2 和 COX2（PTGS2）高表达在转移性结直肠癌中的影响
ecancermedicalscience Pub Date : 2024-02-08 DOI: 10.3332/ecancer.2024.1666
Álvaro M C Caldas, Warley A Nunes, Rodrigo Taboada, Marcelle G Cesca, Janaína N Germano, Rachel P. Riechelmann
{"title":"oss of CDX2 and high COX2 (PTGS2) expression in metastatic colorectal cancer","authors":"Álvaro M C Caldas, Warley A Nunes, Rodrigo Taboada, Marcelle G Cesca, Janaína N Germano, Rachel P. Riechelmann","doi":"10.3332/ecancer.2024.1666","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1666","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"13 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139853319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of modern parameters and their relationship with recurrence risk as assessed by Oncotype DX: real-world evidence Oncotype DX评估的现代参数的作用及其与复发风险的关系：真实世界的证据
ecancermedicalscience Pub Date : 2024-02-06 DOI: 10.3332/ecancer.2024.1664
Dana Narváez, Jorge Nadal, A. Nervo, V. Costanzo, Claudio Paletta, F. Petracci, S. Rivero, A. Ostinelli, F. Coló, Loza Martín, V. Fabiano, Luciana Sabatini, Azul Perazzolo, Mora Amat, Matias Chacon, F. Waisberg
{"title":"The role of modern parameters and their relationship with recurrence risk as assessed by Oncotype DX: real-world evidence","authors":"Dana Narváez, Jorge Nadal, A. Nervo, V. Costanzo, Claudio Paletta, F. Petracci, S. Rivero, A. Ostinelli, F. Coló, Loza Martín, V. Fabiano, Luciana Sabatini, Azul Perazzolo, Mora Amat, Matias Chacon, F. Waisberg","doi":"10.3332/ecancer.2024.1664","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1664","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"28 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139798335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge, practice and communication barriers for oncology doctors in Chile when addressing the sexuality of their patients 智利肿瘤科医生在处理患者性问题时遇到的知识、实践和沟通障碍
ecancermedicalscience Pub Date : 2024-02-06 DOI: 10.3332/ecancer.2024.1665
Daniela Paz Rojas Miranda, C. Micolich V, Karen Goset, Sofia P Salas
{"title":"Knowledge, practice and communication barriers for oncology doctors in Chile when addressing the sexuality of their patients","authors":"Daniela Paz Rojas Miranda, C. Micolich V, Karen Goset, Sofia P Salas","doi":"10.3332/ecancer.2024.1665","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1665","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"173 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139859593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of modern parameters and their relationship with recurrence risk as assessed by Oncotype DX: real-world evidence Oncotype DX评估的现代参数的作用及其与复发风险的关系：真实世界的证据
ecancermedicalscience Pub Date : 2024-02-06 DOI: 10.3332/ecancer.2024.1664
Dana Narváez, Jorge Nadal, A. Nervo, V. Costanzo, Claudio Paletta, F. Petracci, S. Rivero, A. Ostinelli, F. Coló, Loza Martín, V. Fabiano, Luciana Sabatini, Azul Perazzolo, Mora Amat, Matias Chacon, F. Waisberg
{"title":"The role of modern parameters and their relationship with recurrence risk as assessed by Oncotype DX: real-world evidence","authors":"Dana Narváez, Jorge Nadal, A. Nervo, V. Costanzo, Claudio Paletta, F. Petracci, S. Rivero, A. Ostinelli, F. Coló, Loza Martín, V. Fabiano, Luciana Sabatini, Azul Perazzolo, Mora Amat, Matias Chacon, F. Waisberg","doi":"10.3332/ecancer.2024.1664","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1664","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"378 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139858532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge, practice and communication barriers for oncology doctors in Chile when addressing the sexuality of their patients 智利肿瘤科医生在处理患者性问题时遇到的知识、实践和沟通障碍
ecancermedicalscience Pub Date : 2024-02-06 DOI: 10.3332/ecancer.2024.1665
Daniela Paz Rojas Miranda, C. Micolich V, Karen Goset, Sofia P Salas
{"title":"Knowledge, practice and communication barriers for oncology doctors in Chile when addressing the sexuality of their patients","authors":"Daniela Paz Rojas Miranda, C. Micolich V, Karen Goset, Sofia P Salas","doi":"10.3332/ecancer.2024.1665","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1665","url":null,"abstract":"","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"264 22‐25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139799570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical usefulness of the patient-generated subjective global assessment short form© for nutritional screening in patients with head and neck cancer: a multicentric study 患者自制主观全面评估简表© 在头颈癌患者营养筛查中的临床实用性：一项多中心研究
ecancermedicalscience Pub Date : 2024-02-01 DOI: 10.3332/ecancer.2024.1662
Mariana Duarte Azevedo, N. B. de Pinho, Patricia de Carvalho Padilha, Livia Costa de Oliveira, Wilza Arantes Ferreira Peres
{"title":"Clinical usefulness of the patient-generated subjective global assessment short form© for nutritional screening in patients with head and neck cancer: a multicentric study","authors":"Mariana Duarte Azevedo, N. B. de Pinho, Patricia de Carvalho Padilha, Livia Costa de Oliveira, Wilza Arantes Ferreira Peres","doi":"10.3332/ecancer.2024.1662","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1662","url":null,"abstract":"Nutritional screening and assessment are considered essential steps in nutritional care for cancer patients, malnutrition remains underreported in clinical practice. The aim of this study was to analyse the clinical usefulness of the Patient-Generated Subjective Global Assessment short form (PG-SGA SF © ) for nutritional screening in patients with head and neck cancer (HNC). This is a multicentre, cross-sectional study involving patients with HNC. The final score of the PG-SGA SF © was obtained and the nutritional status was diagnosed using the Patient-Generated Subjective Global Assessment (PG-SGA) ® , classifying them as well-nourished or malnourished. Receiver operating characteristic curve, ordinal logistic regression, and C-statistic were used. In total, 353 patients with HNC were enrolled and the prevalence of malnutrition, according to the PG-SGA ® , was 64.02% and the median final score of PG-SGA SF © was 11 points. The final score of the PG-SGA SF © had high accuracy (area under the curve = 0.915), and scores ≥9 had the best performance in diagnosing malnutrition. PG-SGA SF © final score ≥9 was associated with malnutrition (odds ratio = 28.32, 95% confidence interval= 15.98–50.17), with excellent discriminatory power (C-statistic = 0.872). In conclusion, the PG-SGA SF © demonstrated excellent performance for nutritional screening in patients with HNC. Given that it is a simple instrument that is faster to administer than the PG-SGA ® , we recommend its use in clinical practice among such patients.","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"16 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139882752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survival rate of cervical cancer: a five year review at a Major Teaching Hospital in Ghana, West Africa 宫颈癌存活率：西非加纳一家主要教学医院的五年回顾
ecancermedicalscience Pub Date : 2024-02-01 DOI: 10.3332/ecancer.2024.1663
Joseph Daniels, Kwesi Asante, Judith Naa Odey Tackie, K. A. Kyei
{"title":"Survival rate of cervical cancer: a five year review at a Major Teaching Hospital in Ghana, West Africa","authors":"Joseph Daniels, Kwesi Asante, Judith Naa Odey Tackie, K. A. Kyei","doi":"10.3332/ecancer.2024.1663","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1663","url":null,"abstract":"Cervical cancer (CC) is one of the leading causes of cancer-related deaths among females in Ghana. Despite the magnitude of the public health challenge posed by CC in Ghana, survival data as well as reported incidence and mortality rates are primarily based on studies conducted in the capital city of the country. Even though age at diagnosis is known to affect the overall survival of CC patients, the role of this factor in the prognosis of CC patients in Ghana has not been sufficiently explored. The aim of this study was to determine the 5-year survival rate of Ghanaian woman treated for CC at a large tertiary healthcare facility in Ghana. This research was a single-institution-based quantitative retrospective cohort study conducted among patients with histopathologically confirmed CC. Clinical and socio-demographic data were retrieved from patients’ medical records. Data analysis was done using the Statistical Package for the Social Sciences software version 23. Kaplan Meier curves were used to present the survival rates and median survival time. The peak age at diagnosis was between 45 and 80 years with the modal age group of patients between 75 and 80 years. The mean age at diagnosis was 63.3 ± 15.7 years ranging from 27 to 104 years. The overall survival rates at 1, 3 and 5 years were 76.5%, 51.5% and 32.4%, respectively. The median survival time was 65.8 months. Age < 50 years was associated with higher survival estimates than age >50 years. The 5-year over-all survival rate of CC patients reported in this study (32.4%) is relatively low compared with countries in the developed world but like previous reports at other healthcare facilities in Ghana as well as in other underdeveloped countries.","PeriodicalId":502597,"journal":{"name":"ecancermedicalscience","volume":"63 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139873915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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