Journal of Lower Genital Tract Disease最新文献_第5页

Recommendations for Use of p16/Ki67 Dual Stain for Management of Individuals Testing Positive for Human Papillomavirus: Erratum. 关于使用 p16/Ki67 双染色法处理人类乳头瘤病毒检测呈阳性者的建议》：勘误。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 DOI: 10.1097/LGT.0000000000000825

引用次数: 0

Awards Presented as Part of the ASCCP 2024 Scientific Meeting on Anogenital & HPV-Related Diseases. ASCCP 2024年肛门生殖器和人乳头瘤病毒相关疾病科学会议颁奖。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 DOI: 10.1097/LGT.0000000000000824

引用次数: 0

Long-Term Effectiveness of Vestibulectomy for the Treatment of Vulvodynia: A Retrospective Cohort Study. 外阴切除术治疗外阴炎的长期疗效：回顾性队列研究

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 Epub Date: 2024-06-12 DOI: 10.1097/LGT.0000000000000810

Nele Coryn, Bart Vergauwe, Steven Weyers, Hans Verstraelen

{"title":"Long-Term Effectiveness of Vestibulectomy for the Treatment of Vulvodynia: A Retrospective Cohort Study.","authors":"Nele Coryn, Bart Vergauwe, Steven Weyers, Hans Verstraelen","doi":"10.1097/LGT.0000000000000810","DOIUrl":"10.1097/LGT.0000000000000810","url":null,"abstract":"Objective: To evaluate the effectiveness and complication rate of vestibulectomy for vulvodynia.Methods: A retrospective cohort study in a teaching and university hospital analyzing patients with vulvodynia with insufficient response to conservative treatment who underwent a vestibulectomy. Data from 114 consecutive vestibulectomy procedures done between September 2009 and October 2018 were retrospectively analyzed. All procedures were performed by the same surgeon.The primary outcome was difference in pain scale (6-point Q-tip test, Nociceptive Rating Scale) between preoperative consultation, postoperative visit, and last follow-up consultation. The secondary outcome was surgical complications, such as wound dehiscence and hematoma.Results: Complete data were available for 80 patients. There was a significant reduction in median pain scores of between 65% and 80% on all 6 evaluated vestibular points during Q-tip tests. The median follow-up was 21 months, ranging from 1 to 92 months (interquartile range [IQR]). Overall, 75% of patients needed no further treatment at the end of the follow-up period. In 22.6% (18/80), a limited wound dehiscence was noted. No other complications were reported nor were there any cases of worsening of the complaints.Conclusion/discussion: In this retrospective cohort study, a significant pain reduction occurred after vestibulectomy in patients who were not responding to conservative treatment. The complication rate of this surgical procedure is low. Vestibulectomy seems to be an effective technique for management of vulvodynia.","PeriodicalId":50160,"journal":{"name":"Journal of Lower Genital Tract Disease","volume":" ","pages":"258-263"},"PeriodicalIF":2.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distribution and Severity of Cervical Intraepithelial Neoplasia in Women With Different Human Papillomavirus: An Analysis From Liaoning Province of Northeastern China. 不同人类乳头瘤病毒女性宫颈上皮内瘤变的分布和严重程度：来自中国东北辽宁省的分析。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 Epub Date: 2024-05-06 DOI: 10.1097/LGT.0000000000000821

Xin Wei, Yi-Hang Zhou, Peng Chen

{"title":"Distribution and Severity of Cervical Intraepithelial Neoplasia in Women With Different Human Papillomavirus: An Analysis From Liaoning Province of Northeastern China.","authors":"Xin Wei, Yi-Hang Zhou, Peng Chen","doi":"10.1097/LGT.0000000000000821","DOIUrl":"10.1097/LGT.0000000000000821","url":null,"abstract":"Objective: Persistent infection with high-risk human papillomavirus (HPV) is a key contributor to cervical intraepithelial neoplasia (CIN), but the relation between high-risk HPV genotypes and the location of CIN lesions remains unclear. The aims of this study were to investigate the most frequent biopsy site of CIN lesions in women with different HPV infection and to analyze the biopsy times, CIN frequency, and the clustering of CIN frequency based on 12-o'clock sites and cervical quadrant locations.Materials and method: We conducted a retrospective study of HPV detection and genotyping at the virology department of our hospital. Colposcopy exams were performed by specialists according to a standardized protocol, and all visually abnormal areas were further biopsied. Pearson chi-squared tests and cluster analyses were implemented to analyze the data.Results: Among 1,381 women enrolled in this study, 933 cases infected with HPV. HPV16, HPV58, and HPV18 were the most common genotypes. The most frequent biopsy site was the 6 o'clock position. The highest frequency of high-grade CIN findings in single-genotype HPV groups was the 6 o'clock position and that for multiple-genotype HPV group was the 12 o'clock location. All CIN clusters were found in the 6 and 12 o'clock biopsy sites, except in the HPV18 group. Quadrant 2 and 4 were clustered in most groups.Conclusions: The 6 and 12 o'clock sites in cervical quadrant 2 and 4 should be targeted during cervical biopsy procedures. These findings can provide clinicians with specific recommendations on the optimal site for CIN biopsy when considering the HPV genotype.","PeriodicalId":50160,"journal":{"name":"Journal of Lower Genital Tract Disease","volume":" ","pages":"231-239"},"PeriodicalIF":2.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fanconi Anemia Complicated by Cervical Precancer, Vulvar, and Oral Squamous Cell Cancer. 宫颈癌前病变、外阴癌和口腔鳞状细胞癌并发范可尼贫血症。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 DOI: 10.1097/LGT.0000000000000809

Tania Day, Lilia Stuart, Yvette Ius, Gholamreza Haqshenas, Suzanne M Garland, James Scurry

引用次数: 0

Deep Learning Diagnostic Classification of Cervical Images to Augment Colposcopic Impression. 对宫颈图像进行深度学习诊断分类，以增强阴道镜印象。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 Epub Date: 2024-05-07 DOI: 10.1097/LGT.0000000000000815

André Aquilina, Emmanouil Papagiannakis

{"title":"Deep Learning Diagnostic Classification of Cervical Images to Augment Colposcopic Impression.","authors":"André Aquilina, Emmanouil Papagiannakis","doi":"10.1097/LGT.0000000000000815","DOIUrl":"10.1097/LGT.0000000000000815","url":null,"abstract":"Objective: A deep learning classifier that improves the accuracy of colposcopic impression.Methods: Colposcopy images taken 56 seconds after acetic acid application were processed by a cervix detection algorithm to identify the cervical region. We optimized models based on the SegFormer architecture to classify each cervix as high-grade or negative/low-grade. The data were split into histologically stratified, random training, validation, and test subsets (80%-10%-10%). We replicated a 10-fold experiment to align with a prior study utilizing expert reviewer analysis of the same images. To evaluate the model's robustness across different cameras, we retrained it after dividing the dataset by camera type. Subsequently, we retrained the model on a new, histologically stratified random data split and integrated the results with patients' age and referral data to train a Gradient Boosted Tree model for final classification. Model accuracy was assessed by the receiver operating characteristic area under the curve (AUC), Youden's index (YI), sensitivity, and specificity compared to the histology.Results: Out of 5,485 colposcopy images, 4,946 with histology and a visible cervix were used. The model's average performance in the 10-fold experiment was AUC = 0.75, YI = 0.37 (sensitivity = 63%, specificity = 74%), outperforming the experts' average YI of 0.16. Transferability across camera types was effective, with AUC = 0.70, YI = 0.33. Integrating image-based predictions with referral data improved outcomes to AUC = 0.81 and YI = 0.46. The use of model predictions alongside the original colposcopic impression boosted overall performance.Conclusions: Deep learning cervical image classification demonstrated robustness and outperformed experts. Further improved by including additional patient information, it shows potential for clinical utility complementing colposcopy.","PeriodicalId":50160,"journal":{"name":"Journal of Lower Genital Tract Disease","volume":" ","pages":"224-230"},"PeriodicalIF":2.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Awards Presented as Part of the ASCCP 2024 Scientific Meeting on Anogenital & HPV-Related Diseases. ASCCP 2024年肛门生殖器和人乳头瘤病毒相关疾病科学会议颁奖。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 DOI: 10.1097/LGT.0000000000000824

引用次数: 0

Dequalinium Chloride for the Treatment of Vulvovaginal Infections: A Systematic Review and Meta-Analysis: Erratum. 用于治疗外阴阴道感染的氯地奎灵：系统回顾与元分析》：勘误。

IF 2.4 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 DOI: 10.1097/LGT.0000000000000823

引用次数: 0

Psychosocial Factors Associated With Vulvodynia. 与外阴炎相关的社会心理因素

IF 3.7 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-05-02 DOI: 10.1097/lgt.0000000000000822

Janice F Queiroz, Antonio C Q Aquino, Ayane C A Sarmento, Beatriz B Siqueira, Heitor D Medeiros, Megan L Falsetta, Tracey Maurer, Ana Katherine Gonçalves

引用次数: 0

Time Differences From Abnormal Cervical Cancer Screening to Colposcopy Between Insurance Statuses. 不同保险状况下从宫颈癌筛查异常到阴道镜检查的时间差异。

IF 3.7 4区医学

Journal of Lower Genital Tract Disease Pub Date : 2024-05-02 DOI: 10.1097/lgt.0000000000000812

Sonia Khurana, Isaiah Smolar, Leslie Warren, Jessica Velasquez, Elianna Kaplowitz, Jeanette Rios, Adriana Pero, Harley Roberts, Mackenzie Mitchell, Ceyda Oner, Cynthia Abraham

引用次数: 0