Journal of Medical and Biological Engineering最新文献

{"title":"Prediction of Thrombosis After Coil Embolization of Unruptured Cerebral Aneurysm by Computational Fluid Dynamics Using Porous Media Modeling","authors":"Masanori Tsuji, Fujimaro Ishida, Yoichi Miura, Takenori Sato, Kazuhiro Furukawa, Ryuta Yasuda, Yasuyuki Umeda, Naoki Toma, Hidenori Suzuki","doi":"10.1007/s40846-023-00839-3","DOIUrl":"https://doi.org/10.1007/s40846-023-00839-3","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Preoperative simulations tailored to the therapeutic device are desirable to predict treatment efficacy. We investigated the hemodynamics associated with complete obliteration (CO) of intracranial aneurysms after endovascular treatment by computational fluid dynamics (CFD) using porous media modeling.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>From June 2015 to December 2020, 48 patients with 55 unruptured aneurysms treated with simple coiling or stent-assisted coiling at our institution were included. Patient-specific geometry models were generated from pre-treatment 3 dimension (D) rotational angiography or 3D computed tomography angiography. We simulated the coil and neck-bridging stent with porous media modeling for steady state analysis and calculated residual flow volume (RFV) associated with thrombosis formation after coil embolization. Patients were classified into CO and non-CO groups based on digital subtraction angiography findings after 6 months of treatment, and the groups were statistically evaluated using the Brunner-Munzel test. The area under the receiver operating characteristic (ROC) curve (AUC) was used to evaluate the diagnostic accuracy in predicting CO.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The aneurysms were classified into 22 CO and 33 non-CO group. There were no significant differences in morphological variables between the two groups. In hemodynamic parameters, RFV was significantly lower in the CO group. The ROC curve analyses showed that RFV with an average flow velocity of more than 0.5 [cm/s] in aneurysm was the most useful to predict CO (AUC, 0.66 [95% CI, 0.51–0.81]; cut-off value, 32.8 mm³; sensitivity, 60.6%; and specificity, 78.9%).</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>These results indicated that CFD could predict aneurysmal CO after coil embolization.</p>","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138547932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Biodegradability and Biocompatibility of Pure Zinc Coated with Zinc Phosphate for Cardiovascular Stent Applications","authors":"Guan-Lin Wu, Chin-En Yen, Yi-Syuan Lin, Ming-Long Yeh","doi":"10.1007/s40846-023-00834-8","DOIUrl":"https://doi.org/10.1007/s40846-023-00834-8","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Percutaneous coronary intervention is widely used as a primary treatment for cardiovascular diseases. In this regard, it has been revealed from studies that zinc is a potential material for use in stents due to its intrinsic physiological relevance, biocompatibility, biodegradability, and pro-regeneration properties. However, localized corrosion and burst release of zinc ions might cause an early implant failure and a risky environment for vascular remodeling. To resolve these drawbacks effectively, a coating of zinc phosphate on pure zinc was fabricated in this study using a microwave-assisted chemical conversion method.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>In this study, a comprehensive analysis was conducted through materials characterization, electrochemical testing, immersion testing, in vitro testing, and hemocompatibility evaluation to quantify the effect of zinc phosphate coating on zinc cardiovascular stents.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>It is revealed that the microstructures of the coatings are mainly composed of zinc phosphate and sodium zinc phosphate. The presence of sodium zinc phosphate could improve corrosion behavior. The assessment of in vitro biocompatibility for the zinc phosphate coatings revealed satisfactory cell viability and a stable and smooth degradation surface for cell adhesion. Furthermore, the zinc phosphate coatings exhibited nonhemolytic properties and inhibitions to the adhesion of platelets.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>The zinc phosphate coatings could exhibit a uniform degradation behavior and a positive biological effect on vascular remodeling, and therefore, these coatings could be a promising surface treatment used in stent optimization for zinc.</p>","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138517057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"X-Ray CT-Based Evaluation of Dorsal Rotation Angles and Axes of the 1st–5th Tarsometatarsal Joints","authors":"Satoshi Shimawaki, Koyo Aoki, Hidenori Iwasa, Harushi Mori","doi":"10.1007/s40846-023-00840-w","DOIUrl":"https://doi.org/10.1007/s40846-023-00840-w","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>The tarsometatarsal (TMT) joints play crucial roles in walking and slow running. Some studies have treated the 1st to 5th TMT joints collectively as a single joint. However, few studies have examined each individual joint within the 1st to 5th TMT joints separately. This study sought to determine the rotation angles and axes of the 1st–5th TMT joints as each metatarsal head was dorsally displaced in vivo.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>CT imaging was conducted on 11 subjects under six conditions: a basic posture and isolated metatarsal movement postures in which one of the 1st to 5th metatarsals was dorsally displaced with a load of 55 N. The helical axis parameters (rotation angle and rotation axis) of the metatarsal were calculated by transitioning from the basic posture to each isolated metatarsal movement posture.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Multiple comparison testing on the dorsal rotation angles showed significant differences between all TMT joints, except between the 1st and 4th TMT joints and between the 1st and 5th TMT joints (<i>p</i> &lt; 0.01). The 2nd TMT joint exhibited a significantly lower dorsal rotation angle than the other TMT joints. By transitioning from the 1st to the 5th TMT joints, the transversal plane rotation axis shifted from lateral-anterior to -posterior, while that of the sagittal plane shifted from anterior- to posterior-inferior.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>This study provided the rotation angles and axes of the 1st–5th TMT joints in vivo. The data provide a useful reference dataset for selecting diseased feet and developing new foot orthoses.</p>","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138492503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transfer Learning Enhanced Cross-Subject Hand Gesture Recognition with sEMG","authors":"Shenyilang Zhang, Yinfeng Fang, Jiacheng Wan, Guozhang Jiang, Gongfa Li","doi":"10.1007/s40846-023-00837-5","DOIUrl":"https://doi.org/10.1007/s40846-023-00837-5","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>This study explores the emerging field of human physical action classification within human–machine interaction (HMI), with potential applications in assisting individuals with disabilities and robotics. The research focuses on addressing the challenges posed by diverse sEMG signals, aiming for improved cross-subject hand gesture recognition.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>The proposed approach utilizes deep transfer learning technology, employing multi-feature images (MFI) generated through grayscale conversion and RGB mapping of numerical matrices. These MFIs are fed as input into a fine-tuned AlexNet model. Two databases, ISRMyo-I and Ninapro DB1, are employed for experimentation. Rigorous testing is conducted to identify optimal parameters and feature combinations. Data augmentation techniques are applied, doubling the MFI dataset. Cross-subject experiments encompass six wrist gestures from Ninapro DB1 and thirteen gestures from ISRMyo-I.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The study demonstrates substantial performance enhancements. In Ninapro DB1, the mean accuracy achieves 86.16%, showcasing a 13.25% improvement over the best-performing traditional decoding method. Similarly, in ISRMyo-I, a mean accuracy of 70.41% is attained, signifying a 7.4% increase in accuracy compared to traditional methods.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>This research establishes a robust framework capable of mitigating cross-user differences in hand gesture recognition based on sEMG signals. By employing deep transfer learning techniques and multi-feature image processing, the study significantly enhances the accuracy of cross-subject hand gesture recognition. This advancement holds promise for enriching human–machine interaction and extending the practical applications of this technology in assisting disabled individuals and robotics.</p>","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138492502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanotechnology Potent Photothermal and Photodynamic Immunotherapies of Cancer","authors":"Abduladheem Turki Jalil, Noora. G. Al-Fatlawi, Lubna R. Al-Ameer, Mustafa Asaad Rasol, Jabbar Hassoon Zamil Al-Tamimi, Muna S. Merza, Ronak Taher Ali, Rahman S. Zabibah, Farah Al-Hili","doi":"10.1007/s40846-023-00836-6","DOIUrl":"https://doi.org/10.1007/s40846-023-00836-6","url":null,"abstract":"","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135137090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practically Feasible Sensor-Embedded Kinetic Assessment Piano System for Quantifying Striking Force of Digits During Piano Playing","authors":"Kuan-Yin Lai, Chieh-Hsiang Hsu, Yu-Chen Lin, Chung-Hung Tsai, Cheng-Feng Lin, Li-Chieh Kuo, Fong-Chin Su","doi":"10.1007/s40846-023-00835-7","DOIUrl":"https://doi.org/10.1007/s40846-023-00835-7","url":null,"abstract":"Abstract Purpose Understanding the pathogenesis of playing-related hand disorders through investigations based on coordination and biomechanical perspectives is indispensable. This study aimed to establish a sensor-embedded kinetic assessment piano system (SeKAPS) and conduct reliability and validity tests for this system. In addition, the differences in digit coordination between professional pianists and non-musicians were investigated. Methods Twelve subminiature load cells were embedded in the middle of the 12 corresponding keys of an upright piano. A customized calibrated system with a load cell was used to establish the criterion-related validity of the SeKAPS. The reliability of the SeKAPS was determined by 22 volunteer pianists. The other ten professional pianists and ten non-musicians were recruited to indicate the feasibility of the SeKAPS to distinguish the performing differences between groups. Results The R 2 values of regression analyses for the load cells were 0.993–0.999 ( p < 0.001), indicating high validity. The ICC values of the modified keys were 0.82–0.93, indicating high reliability. The results indicate that SeKAPS is accurate in detecting the striking force of digits during piano playing. Significant differences existed in the mean peak force and mean CVs of the peak force of the specific digits between the two groups. The results showed differences in finger control strategies between the pianists and non-musicians. Conclusion The SeKAPS may provide a valuable assessment for assisting pianists in understanding digit force control and movement strategies to achieve efficient digit coordination.","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135432569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accumulated Hepatic Steatosis Grades Predicted by T2*-IDEAL Fat Fraction","authors":"Chang-Hsien Liu, Hing-Chiu Chang, Yi-Jui Liu, Wei-Ching Lin, Chi-Feng Hsieh, Te-Pao Lin, Cheng-Hsuan Juan, William Tzu-Liang, Chun-Jung Juan","doi":"10.1007/s40846-023-00819-7","DOIUrl":"https://doi.org/10.1007/s40846-023-00819-7","url":null,"abstract":"","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135870837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silk Fibroin Based Core-Shell Nanofibers Loaded with ZnO Nanoparticles: An Ideal Candidate for Designing a Medicated Wound Dressing","authors":"Sohrab Moradi, Shahram Nazarian, Peiman Brouki Milan, Mohammad Ali Nilforoushzadeh, Jamil Zargan","doi":"10.1007/s40846-023-00821-z","DOIUrl":"https://doi.org/10.1007/s40846-023-00821-z","url":null,"abstract":"","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136104809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tissue Engineering for Sciatic Nerve Repair: Review of Methods and Challenges","authors":"Yasaman Ebrahimi-kia, Parivash Davoudi, Sima Bordbar","doi":"10.1007/s40846-023-00833-9","DOIUrl":"https://doi.org/10.1007/s40846-023-00833-9","url":null,"abstract":"","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136262141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fully Automated Detection of Osteoporosis Stage on Panoramic Radiographs Using YOLOv5 Deep Learning Model and Designing a Graphical User Interface","authors":"Muhammet Üsame ÖZİÇ, Melek Tassoker, Fatma Yuce","doi":"10.1007/s40846-023-00831-x","DOIUrl":"https://doi.org/10.1007/s40846-023-00831-x","url":null,"abstract":"","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136262788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}