Polski przeglad chirurgiczny最新文献

{"title":"iWOUND telemedicine application in the practice of the surgical department - who uses it?","authors":"Korneliusz Pieczyński, Krzysztof Karaś, Aneta Synakiewicz, Tomasz Banasiewicz","doi":"10.5604/01.3001.0054.9904","DOIUrl":"https://doi.org/10.5604/01.3001.0054.9904","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Despite being a potentially avoidable complication, surgical site infection (SSI) remains the most common cause of postoperative complications in surgical wards. Timely medical consultation plays a crucial role in outpatient wound care when concerning symptoms related to wound healing arise. However, an excessive number of inpatient visits leads to a significant increase in patients attending general surgery clinics and the associated costs of postoperative care. Telemedicine (TM) may offer a solution to this problem. The iWound application facilitates wound healing monitoring and may aid in early detection of SSI symptoms.&lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; Therefore, this study aimed to characterize the group of patients utilizing the iWound application, conclusion of this analysis are included in this manuscript.&lt;br&gt;&lt;br&gt;&lt;b&gt;Materials and methods:&lt;/b&gt; The study was conducted among adult patients who underwent either elective or emergency surgical procedures. Patients received access to the application during hospitalization for postoperative monitoring. Surveys regarding the use of the iWound application in the form of observation journals were conducted within 30 days postoperatively. The study does not bear the characteristics of a medical experiment, which was certified by the Bioethics Committee of the Poznań University of Medical Sciences, number 911/23.&lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; The study included 104 participants aged 18-86 years, with 85.6% utilizing the application. The highest percentage of iWound users was observed in the 18-45 age group (94.4%). All participants who completed therapy with iWound reported satisfaction with its use during the recovery period. Four users developed SSI.&lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; The iWound application was most frequently utilized by younger individuals residing in urban areas and cigarette smokers. There was a higher percentage of willingness to use the application for postoperative wound monitoring among individuals undergoing major and emergency surgical procedures.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"97 2","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indocyanine green fluorescent imaging (ICG-FI) in esophagectomy: single-center experience.","authors":"Jakub Migoń, Michał Bąk, Maja Molska, Roman Lewandowski, Tomasz Piłat, Pawel Zielinski, Dawid Murawa","doi":"10.5604/01.3001.0054.9779","DOIUrl":"https://doi.org/10.5604/01.3001.0054.9779","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Gold standard treatment for locally advanced esophageal cancer is subtotal resection of the esophagus with resection of regional lymph nodes. Despite being performed in experienced and specialized centers, this procedure is associated with a high rate of complications. Complications such as anastomotic fistula and leakage can be life-threatening, primarily resulting from inadequate blood circulation in the anastomosis area. &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; The aim of the study is to present the results of intraoperative indocyanine green (ICG) application in order to verify the adequate perfusion in esophagogastric anastomosis. &lt;br&gt;&lt;br&gt;&lt;b&gt;Materials and methods:&lt;/b&gt; This is a single-center prospective analysis of 32 patients who underwent subtotal esophagectomy with regional lymph node resection for esophageal carcinoma. In all cases, intraoperative perfusion assessment using ICG fluorescence imaging (ICG-FI) was performed. Patient characteristics, comorbidities, and postoperative outcomes were analyzed, with treatment effects monitored for up to 1 year postoperatively. &lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; Six patients required gastric conduit reduction due to poor blood perfusion visualized by intraoperative ICG-FI. Anastomotic leakage occurred in two cases, which were managed endoscopically with endo-vac therapy and esophageal stent placement. The remaining patients did not require additional surgical interventions during the postoperative course. &lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; The use of ICG dye in esophageal surgery appears to be a beneficial tool for objective assessment of perfusion that may be a valuable prediction factor in the postoperative course.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"97 2","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The assesement of the long-term effects of kidney transplantation, including the incidence of malignant tumors, in recipients operated on between 2006 and 2015 - a cohort study and literature review.","authors":"Wojciech Ciesielski, Weronika Frąk, Julita Gmitrzuk, Piotr Kuczyński, Tomasz Klimczak, Adam Durczyński, Janusz Strzelczyk, Piotr Hogendorf","doi":"10.5604/01.3001.0054.9677","DOIUrl":"https://doi.org/10.5604/01.3001.0054.9677","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Chronic kidney disease (CKD) is a global public health problem, occurring more frequently in developed countries. In Poland, it affects approximately 4 million people, which constitutes 10.8% of the population. End-stage renal disease (ESRD) requires renal replacement therapy - dialysis therapy or kidney transplantation. Kidney transplantation, supported by immunosuppressive therapy, is the preferred method of treating ESRD, improving the quality and length of life of patients.&lt;b&gt;Aim and Methods:&lt;/b&gt; The aim of the study was to determine the long-term effects of kidney transplantation, including proper graft function, the frequency of adverse effects of immunosuppressive therapy, the degree of patient compliance with therapeutic recommendations, and the incidence of malignancies. A survey was conducted in a group of 137 patients who underwent kidney transplantation between 2006 and 2015. Hospitalization data were also analyzed, including age, body weight and blood type of the recipient.&lt;b&gt;Results:&lt;/b&gt; Of the 137 patients studied, 61 were women and 76 were men. The mean age of the patients was 45.1 years. The most common etiology of CKD was glomerulonephritis. After kidney transplantation, 86.86% of patients declared normal graft function. Post-transplant weight gain was noted in 75.18% of patients. 11.68% of recipients developed malignancies, with an average time from transplantation to diagnosis of 5.1 years. Of the patients with cancer, 93.75% maintained normal graft function.&lt;b&gt;Conclusions:&lt;/b&gt; Long-term effects of kidney transplantation are satisfactory, with a high percentage of patients maintaining normal graft function. Complications associated with immunosuppressive therapy are comparable to literature data. It is necessary to increase patient awareness of modifiable risk factors to improve treatment outcomes. The incidence of malignancy after transplantation is lower than in the literature, but the methodological limitations of the study must be taken into account. Cancer treatment had no significant effect on graft function in most cases.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"97 2","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for postoperative morbidity after ventral hernia repair in patients with liver cirrhosis. A single tertiary center cohort.","authors":"Dimitrios Prassas, Stephan Oliver David, Maria Chara Stylianidi, Apostolos Konstantinou, Wolfram Trudo Knoefel, Sascha Vaghiri","doi":"10.5604/01.3001.0054.9012","DOIUrl":"https://doi.org/10.5604/01.3001.0054.9012","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Ventral hernias are common among patients with liver cirrhosis.&lt;b&gt;Aim:&lt;/b&gt; The aim of our work was to evaluate potential risk factors for major postoperative morbidity after ventral hernia repair in cirrhotic patients.&lt;b&gt;Material and methods:&lt;/b&gt; A retrospective cohort study was performed in 45 consecutive cirrhotic patients that underwent ventral hernia repair between 2005 and 2022. Major morbidity was defined as Clavien-Dindo ≥ IIIa at 30 days postoperatively. Uni- and multivariate analysis was performed to identify risk factors for major postoperative complications.&lt;b&gt;Results:&lt;/b&gt; In our cohort, we observed an overall postoperative 30-day morbidity rate of 53.33% (n = 24), with 40% (n = 18) of cases classified as Clavien-Dindo IIIa or above. Elevated serum creatinine level preoperatively was identified as a statistically significant risk factor, both in the uni- as well as the multivariate analysis for major morbidity (OR = 31.08; 95%CI [29.51-32.65]; P = 0.028).&lt;b&gt;Conclusions:&lt;/b&gt; Increased creatinine levels were found to be a significant modifiable factor for major morbidity after ventral hernia repair in cases with cirrhosis. This finding underlines the impact of preoperative medical management of cirrhotic patients on postoperative outcome in this patient population.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"97 2","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transforming Growth Factor-Beta (TGF-β) Dynamics in Thyroid Pathologies: A Comprehensive Analysis of Pre- and Post-Surgery Levels in Differentiated Thyroid Cancer and Nodular Goiter.","authors":"Adam Bednarczyk, Grzegorz Kowalski, Agata Gawrychowska, Jacek Gawrychowski","doi":"10.5604/01.3001.0054.8492","DOIUrl":"https://doi.org/10.5604/01.3001.0054.8492","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; In various pathological conditions, including cancer, transforming growth factor-beta (TGF-β) emerges as a pivotal cytokine.&lt;b&gt;Aim:&lt;/b&gt; This study sought to evaluate TGF-β concentrations in blood serum samples and explore potential associations between pre- and post-surgery TGF-β levels in patients with differentiated thyroid cancer and forms of nodular goiter.&lt;b&gt;Material and methods:&lt;/b&gt; A total of 70 patients were included, aged 26 to 79, undergoing thyroidectomy for: differentiated thyroid cancer (11), neutral nodular goiter (46), and hyperactive nodular goiter (13). Serum TGF-β1 values were assessed using the Bio-Plex Pro™ Human Cytokine Assay from Bio-Rad Laboratories, and data were analyzed with Bio-Plex Manager™ software.&lt;b&gt;Conclusions:&lt;/b&gt; This investigation aimed to provide insights into the dynamics of TGF-β concentrations in the context of thyroid pathologies, utilizing a comparative approach before and after surgical intervention.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"97 2","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety enhancement in Nuss procedure: sternal elevation and thoracoscopic dissection.","authors":"Mateusz Ciopiński, Michał Marciniak, Krzysztof Bogucki, Maciej Mitrowski, Weronika Chacińska, Paulina Chodnicka, Piotr Kaliciński","doi":"10.5604/01.3001.0054.8463","DOIUrl":"https://doi.org/10.5604/01.3001.0054.8463","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; &lt;i&gt;Pectus excavatum&lt;/i&gt; (PE) is the most common chest wall deformity. Minimally invasive repair techniques based on the Nuss procedure are a mainstay of treatment. However, intraoperative cardiac injury, though rare, can be a devastating complication.&lt;b&gt;Aim:&lt;/b&gt; This study aimed to evaluate a modification of the Nuss procedure designed to minimize the risk of serious complications.&lt;b&gt;Material and methods:&lt;/b&gt; A retrospective analysis of medical records for 38 patients treated with a modified Nuss procedure forPE was conducted. The specific modifications to the surgical technique were described.&lt;b&gt;Results:&lt;/b&gt; No intraoperative complications were observed in the analyzed patients. In 3 patients (7.9%), early complicationsafter surgery occurred, with none relating to the modification of the surgical technique.&lt;b&gt;Discussion:&lt;/b&gt; Minimally invasive PE repair carries a risk of serious complications, prompting the development of variousmodifications. These modifications often involve techniques of sternal elevation and retrosternal dissection to achieve clearview throughout the procedure.&lt;b&gt;Conclusions:&lt;/b&gt; The Nuss procedure with sternal elevation and thoracoscopic retrosternal dissection offers a simple andpotentially safer approach to PE repair.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"97 2","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five-year survival in laparoscopically operated colorectal cancer patients based on own material: A comparison of risk factors.","authors":"Mariusz Uryszek, Piotr Kwietniak, Agnieszka Iga Gonciarska, Wiesław Tarnowski","doi":"10.5604/01.3001.0054.8322","DOIUrl":"https://doi.org/10.5604/01.3001.0054.8322","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; The laparoscopic method is a treatment method with proven effectiveness. In 2008, we started treating patients with this method. We present treatment results in unselected patients. This is a retrospective observation.&lt;b&gt;Aim:&lt;/b&gt; The present article demonstrates the results of a 5-year postoperative follow-up in a group of patients who underwent laparoscopic colorectal surgery. We also assessed the importance of basic risk factors such as tumor stage, age, gender, type of complication, and conversion requirement for the survival of patients.&lt;b&gt;Material and methods:&lt;/b&gt; In total, 212 patients with colon or rectal cancer were subjected to a standard laparoscopic procedure. In the case of rectal and sigmoid tumors, a mini-laparotomy was performed in the left iliac fossa. In the case of right hemicolectomy, an anastomosis was created above the abdominal walls. The results were statistically processed. As many as 80% (171) of patients were followed up.&lt;b&gt;Results:&lt;/b&gt; Overall survival was 66.08%, while cancer-related survival - 61.4%. The cancer recurrence rate was 21.47%. In a multivariate analysis: assuming the same age of diagnosis, an increase in tumor stage by one category according to Dukes causes a 102.532-fold increase in the risk of death within the first 5 years after surgery.&lt;b&gt;Conclusions:&lt;/b&gt; The results of laparoscopic colorectal cancer treatment in our material are similar to those reported in the literature. The most important prognostic factor for the long-term survival of patients in our material was the stage of cancer.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"97 2","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional status and related factors in gastric cancer patients after gastrectomy: a cross-sectional study.","authors":"Tomasz Muszyński, Tomasz Jędrychowski, Adrianna Witalewska, Aldona Gawlewicz-Czepiel, Karina Polak, Michał Spieszny, Antoni Szczepanik","doi":"10.5604/01.3001.0054.8165","DOIUrl":"https://doi.org/10.5604/01.3001.0054.8165","url":null,"abstract":"<p><p>&lt;b&gt;Introduction: &lt;/b&gt; Gastrectomy due to gastric cancer induces metabolic changes in body composition, directly affecting nutritional status. &lt;br&gt;&lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; The aim of this cross-sectional study was to investigate the nutritional status and related factors in gastric cancer patients after total and subtotal gastrectomy.&lt;br&gt;&lt;br&gt;&lt;b&gt;Materials and methods:&lt;/b&gt; A total of 41 patients who underwent gastrectomy due to gastric cancer were included: 20 patients (48.8%) with total gastric resection and 21 patients (51.2%) with subtotal resection were enrolled. The evaluation was performed over a follow-up period ranging from two to four years after surgery during routine oncological monitoring visits. The laboratory tests, bioimpedance parameters, physical activity, and quality of life were evaluated.&lt;br&gt;&lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; The only statistically significant differences included BMI, fat percentage, fat mass, and metabolic age in the subtotal gastrectomy group. Overall, post-gastrectomy patients showed suboptimal vitamin D concentration and low physical activity level and were found to be at risk of malnutrition assessed with prealbumin concentration and total lymphocyte count.&lt;br&gt;&lt;br&gt;&lt;b&gt;Discussion:&lt;/b&gt; The nutritional status and life quality do not significantly differ between total and subtotal gastric cancer patients.&lt;br&gt;&lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; The nutritional status and life quality do not significantly differ between total and subtotal post-gastrectomy patients in long-term follow-up. The analysis of selected parameters suggests that post-gastrectomy patients are at risk of malnutrition.&lt;br&gt;&lt;br&gt;&lt;b&gt;Study significance:&lt;/b&gt; The presented study brings better insight into the nutritional status of gastric cancer patients after gastrectomy in long-term follow-up.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"97 2","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The \"No-Fault\" Principle in the Context of the Compensation System for Patients Affected by Bariatric Surgeons&apos; Medical Services.","authors":"Michał Gornowicz, Jakub Zięty, Natalia Dowgiałło-Gornowicz","doi":"10.5604/01.3001.0054.8166","DOIUrl":"https://doi.org/10.5604/01.3001.0054.8166","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; The high risk associated with bariatric procedures prompts an analysis of the civil liability of bariatric surgeons towards patients. This liability may arise from medical errors, lack of appropriate patient consent, or insufficient information about possible procedure outcomes. The high risk of postoperative complications, independent of physician errors, makes bariatrics a particularly significant field for considering the &quot;no-fault&quot; principle.&lt;b&gt;Aim:&lt;/b&gt; The aim of this paper is to demonstrate the need to introduce the &quot;no-fault&quot; principle into the Polish legal system in the context of medical services provided by bariatric surgeons. The adopted methodology includes a dogmatic-legal analysis of existing regulations and historical-legal and statistical methods, including data from the Supreme Medical Chamber regarding proceedings before professional liability committees.&lt;b&gt;Materials and methods:&lt;/b&gt; The study employed the dogmatic-legal method, analyzing data on disciplinary proceedings and types of violations committed by surgeons in the years 2022-2023.&lt;b&gt;Results:&lt;/b&gt; Analysis of statistics on disciplinary proceedings against bariatric surgeons and other specialists confirms that most complaints are unfounded, causing unnecessary stress for doctors and reducing the quality of medical services they provide.&lt;b&gt;Conclusions:&lt;/b&gt; The current Polish compensation law is complicated and time-consuming, prompting consideration of the &quot;no-fault&quot; principle as an alternative. This principle would involve the creation of a compensation fund, from which payments would be made to patients upon the determination of a medical event by an appropriate committee. Implementing the &quot;no-fault&quot; principle aims to streamline the compensation process, eliminating the need for lengthy court proceedings. Compensation proceedings in connection with medical events are known to the Polish legislator, as they are provided for in the Act on Patients' Rights and the Patients' Rights Ombudsman. The training and certification system for bariatric surgeons indicates that their high qualifications and adherence to the principle of due diligence justify the introduction of the &quot;no-fault&quot; principle into Polish law, which would improve working conditions for doctors and the quality of patient care.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"97 2","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of anal fissures using the new TRPM8 receptor therapy - own experience.","authors":"Labib Zair, Dorota Zair, Szadi Zair, Katarzyna Zair-Mościbroda","doi":"10.5604/01.3001.0054.7946","DOIUrl":"https://doi.org/10.5604/01.3001.0054.7946","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Anal fissure, a longitudinal or oval crack in the anal anoderm above the dentate line, is one of the most common diseases of the anal area. The following article shows the effectiveness of anal fissure treatment based on our own experience, using new receptor therapy in the form of Procto-Zac Memethol Barrier Spray [(1R,2S,5R)-2-isopropyl-5-methylcyclohexanol, sodium hydrogen carbonate, 7-(dimethylamino) phenothiazin-3-ylidene]- dimethylazanium; chloride, 1,2-propanediol, purified water], preparation containing soluble fiber and oral probiotic.&lt;b&gt;Aim:&lt;/b&gt; The aim of the following article is to present our experience and observations in the conservative treatment of acute and chronic anal fissure using Procto-Zac Memethol Barrier Spray and preparations containing soluble fiber and oral probiotic.&lt;b&gt;Material and methods:&lt;/b&gt; The study included a group of 120 patients with anal fissure between 18 and 45 years of age. Each patient in the group received a therapy consisting of Procto-Zac Memethol Barrier Spray (8 sprays once a day, 2 packages) and preparation containing fiber and oral probiotic. A high-fiber, gluten-free and lactose-free diet was also recommended. A follow-up was carried out in our clinic after 4 and 8 weeks. If the symptoms do not disappear completely, also after 3 months from the start of treatment.&lt;b&gt;Results:&lt;/b&gt; Complete relief of symptoms was achieved in 62 patients after 4 weeks of treatment. After 8 weeks, complete relief of symptoms was achieved in another 49 people. In 6 people, after 3 months of treatment, the symptoms were partially relieved, but the anal fissure was not completely healed. Three people did not come for a follow-up visit. In 20 patients, skin burning around the anus was observed during the above therapy.The above symptoms did not require discontinuation of Procto-Zac Memethol Barrier Spray therapy and disappeared after completion of treatment. No other side effects of the preparations used were found.&lt;b&gt;Conclusions:&lt;/b&gt; According to our observations, the use of new TRPM8 receptor therapy MemeThol Barrier Spray, a preparation containing soluble fiber and oral probiotic, turned out to be an effective method of treating anal fissure. In the future, it is advisable to conduct further studies, including multicenter studies, to assess the full tolerability and effectiveness of the described therapy.</p>","PeriodicalId":501107,"journal":{"name":"Polski przeglad chirurgiczny","volume":"96 5","pages":"8-11"},"PeriodicalIF":0.0,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}