Edson Luiz Cetira-Filho DDS MSc PhD, Paulo Goberlânio de Barros Silva DDS MSc PhD, Isabelle de Fátima Vieira Camelo Maia CP, Deysi Viviana Tenazoa Wong MSc PhD, Roberto César Pereira Lima-Júnior Sc PhD, Ravy Jucá Farias DDS, Mayara Alves dos Anjos DDS student, Said Goncalves da Cruz Fonseca CP MSc PhD, Thyciana Rodrigues Ribeiro DDS MSc PhD, Fábio Wildson Gurgel Costa DDS MSc PhD
{"title":"Preemptive vs preventive coadministration of ibuprofen L-arginine and dexamethasone in lower third molar surgeries: a randomized controlled trial","authors":"Edson Luiz Cetira-Filho DDS MSc PhD, Paulo Goberlânio de Barros Silva DDS MSc PhD, Isabelle de Fátima Vieira Camelo Maia CP, Deysi Viviana Tenazoa Wong MSc PhD, Roberto César Pereira Lima-Júnior Sc PhD, Ravy Jucá Farias DDS, Mayara Alves dos Anjos DDS student, Said Goncalves da Cruz Fonseca CP MSc PhD, Thyciana Rodrigues Ribeiro DDS MSc PhD, Fábio Wildson Gurgel Costa DDS MSc PhD","doi":"10.1016/j.oooo.2024.08.008","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.08.008","url":null,"abstract":"To compare the effect of different preemptive and preventive analgesia strategies involving oral coadministration of ibuprofen-arginine (770 mg)–Ib-Ar and dexamethasone (8 mg)-DX, and their respective placebos (P-Ib-Ar and P-DX), four evaluation groups on inflammatory and laboratory parameters, impact on quality of life, pain catastrophizing perception and sleep quality related after lower third molar surgery. A randomized split-mouth, triple-blind, controlled clinical trial was conducted with 48 volunteers. They were allocated depending on the use of Ib-Ar or DX, 1 hour before surgery or immediately postoperatively, discriminating the groups: G1 (Ib-Ar + DX), G2 (Ib-Ar + P-DX), G3 (P-Ib-Ar + DX), and G4 (P-Ib-Ar + P-DX). Pain peaks occurred after 2 h (P-Ib-Ar groups) ( = .003), while the other groups showed peak pain after 4 h ( < .05). Regarding the edema: groups treated with placebos measurements significantly reduced without returning to baseline ( < .001). Regarding laboratory parameters: MPO and MDA levels, the G1 group ( < .001) was the only one showing significant reduction. The use of preemptive and preventive analgesia strategies of Ib-Ar and DX showed that the combined use delayed peak pain, with no difference in edema and trismus. The benefit of coadministration of both strategies was superior to isolated use of drugs.","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yulang Xu BDS, Hanyao Huang MD, Chao Yang MSc, Yang Li MD, Chenghao Li MD, Bing Shi MD, Jingtao Li MD, Yan Wang MD, Qian Zheng MD, Ni Zeng MD
{"title":"Efficacy evaluation of a high-precision simulator of posterior pharyngeal flap pharyngoplasty","authors":"Yulang Xu BDS, Hanyao Huang MD, Chao Yang MSc, Yang Li MD, Chenghao Li MD, Bing Shi MD, Jingtao Li MD, Yan Wang MD, Qian Zheng MD, Ni Zeng MD","doi":"10.1016/j.oooo.2024.07.012","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.07.012","url":null,"abstract":"To improve medical students’ preclinical skills and enable them to quickly comprehend the procedure of posterior pharyngeal flap surgery, our teaching team developed a surgical simulator specifically for pharyngeal flap surgery. Thirteen undergraduate students and 8 first-year residents trained from March to May 2023 participated in simulated surgical training. Initially, multimedia were used to explain and demonstrate to them relevant anatomy, surgical principles, and procedural steps. This was followed by independent simulated surgeries by the students, culminating in the completion of a questionnaire. Independent samples test was used for statistical analysis. Before the simulated surgery, the residents had a greater understanding of the surgical design compared with the undergraduate students. After the simulated surgery, the residents showed not only significantly greater levels of understanding of the surgical design but also increased familiarity with the surgical process and enhanced confidence in independent surgery compared with the undergraduate students. Both groups showed a notable increase in familiarity with the surgical process and confidence in performing surgery independently after the simulated surgery. The surgical simulator demonstrates high clinical fidelity and provides tactile feedback that closely resembles reality. It significantly enhances the understanding and mastery of surgical techniques for young doctors, ultimately improving their surgical skills.","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luiz Eduardo Marinho-Vieira, Maria Clara Rodrigues Pinheiro, Deborah Queiroz Freitas, Reinhilde Jacobs, Christiano de Oliveira-Santos, Alexander Tadeu Sverzut, Matheus L. Oliveira
{"title":"Evaluation of gingival thickness obtained from intraoral scanning registration with cone beam computed tomography at different acquisition modes","authors":"Luiz Eduardo Marinho-Vieira, Maria Clara Rodrigues Pinheiro, Deborah Queiroz Freitas, Reinhilde Jacobs, Christiano de Oliveira-Santos, Alexander Tadeu Sverzut, Matheus L. Oliveira","doi":"10.1016/j.oooo.2024.08.005","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.08.005","url":null,"abstract":"To investigate the reliability of gingival thickness measurements obtained from the registration of intraoral scans with cone beam computed tomography (CBCT) examinations at different acquisition modes. CBCT examinations of 9 porcine hemimandibles were acquired using the OP300 Maxio unit operating at the highest-dose protocol with the smallest voxel size as the reference standard for visualizing the gingival surface. Subsequently, the hemimandibles were surrounded by water to simulate soft tissue attenuation of radiation, and additional CBCT examinations were acquired in 4 modes: Endo, High-resolution, Standard-resolution, and Low-dose. These CBCT datasets were registered with corresponding intraoral scans obtained with the Carestream Dental 3600 intraoral scanning system using the Blue Sky Plan 4 software. Four oral radiologists measured the buccal gingival thickness on cross-sectional reconstructions at 4 measurement sites and 2 distances from the gingival margin in the CBCT reference standard examinations and examinations obtained with water and intraoral scan registration. Multifactorial analysis of variance was used to assess the influence of acquisition mode, measurement site, and distance from the gingival margin on measurements (α = 5%; statistical power = 90%). Buccal gingival thickness measurements obtained via CBCT after registration with intraoral scanning were not significantly influenced by acquisition mode ( = .153) or measurement site ( = .089). Gingival thickness measurements derived from the registration of intraoral scans with CBCT examinations at different acquisition modes appear to be reliable.","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katharina Theresa Obermeier DMD MD, Wenko Smolka, Benjamin Palla, Moritz Kraus, David Steybe, Jens Tobias Hartung, Florian Nepomuk Fegg, Tim Hildebrandt, Ina Dewenter, Nicholas Callahan, Philipp Poxleitner, Sven Otto
{"title":"Antiresorptive therapy in combination with radiation results in enhanced risk for necrosis and associated complications","authors":"Katharina Theresa Obermeier DMD MD, Wenko Smolka, Benjamin Palla, Moritz Kraus, David Steybe, Jens Tobias Hartung, Florian Nepomuk Fegg, Tim Hildebrandt, Ina Dewenter, Nicholas Callahan, Philipp Poxleitner, Sven Otto","doi":"10.1016/j.oooo.2024.07.008","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.07.008","url":null,"abstract":"Patients exposed to a combination of antiresorptive medication and radiotherapy of the head and neck area developing necrosis of the jaw in the course of treatment are extremely rare. Therefore, the aim of this study was to identify the outcome and complications in this highly vulnerable patient cohort. Seventeen patients who received both antiresorptive treatment and radiotherapy (medication-related osteonecrosis of the jaw/osteoradionecrosis = the [MRONJ/ORN] group) in the head and neck area were enrolled in this study. Included patients were treated in our department between 2005 and 2022. Four hundred twenty-four patients with MRONJ (the MRONJ group) and 138 patients with ORN of the jaw were enrolled as two control groups (the ORN group). Demographic data, lesion localization, date of primary diagnosis, clinical symptoms, type of therapy (surgical or non-surgical), details on antiresorptive treatment, outcome, and complications were recorded. Pathological fractures, continuity resection, and recurrence appear more often in patients who receive a combination of antiresorptive treatment and radiotherapy in the head and neck area compared with patients undergoing only one of these treatments. There was a statistically significant difference ( < .001) between the MRONJ/ORN group and the MRONJ group and the MRONJ/ORN group and the ORN group considering recurrence, fracture, and continuity resection. Patients with ORN combined with MRONJ have a 4-times higher risk for developing recurrence compared with patients with MRONJ and a 1.5-times higher risk for recurrence compared with patients with ORN. Jaw fracture and continuity resection appear more often in patients with MRONJ/ORN. Patients under antiresorptive therapy in combination with radiation therapy in the head and neck area have a higher risk for developing complications in case of osteonecrosis of the jaw. Therefore, a strict follow-up care schedule is highly recommended.","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Satu Manninen BDS, Johanna Snäll MD DDS PhD, Tero Puolakkainen DDS PhD, Aleksi Haapanen DDS PhD
{"title":"Severe odontogenic infections in patients with mental disorders—the challenge of ineffective initial treatment","authors":"Satu Manninen BDS, Johanna Snäll MD DDS PhD, Tero Puolakkainen DDS PhD, Aleksi Haapanen DDS PhD","doi":"10.1016/j.oooo.2024.08.002","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.08.002","url":null,"abstract":"This study clarified possible delays and deficiencies in severe odontogenic infection (OI) treatment in patients with mental disorders. Data of hospitalized patients with severe OI were evaluated retrospectively. The outcome variable was preceding health care visits prior to hospitalization. The primary predictor was patient's mental disorder. Explanatory variables were age, sex, smoking, heavy alcohol use, immunocompromised disease or medication, and time span from beginning of symptoms to hospitalization. Also, factors leading to intensive care unit (ICU) care were evaluated. Preceding visits prior to hospitalization were found in 61 (35.5%) out of 172 patients with OI. In total, 27 patients (15.7%) had a current mental disorder, more commonly in women (26.0%) than in men (8.1%) ( = .001). Patients with mental disorders had preceding health care visits related to the current infection notably more often than patients without recent psychiatric history (51.9% vs. 32.4%), = .053. Patient-related treatment delay remained nonsignificant. Heavy alcohol use ( = .010) and smoking ( = .025) predicted ICU treatment, but no association with patient's mental disorder was found. A patient's mental disorder can complicate diagnosis of OI. Effective and timely treatment requires the professional's ability to simultaneously identify the patient's mental health challenges and progressing OI.","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vincent Tran BDS, Michael Qiu BDS MBBS FRACDS (OMS), Santosh Kumar Tadakamadla PhD BDS MDS PGD-HP FHEA MRACDS (DPH), Kai Lee PhD BDSc MBBS MMedSc FRACDS (OMS)
{"title":"Illicit cocaine and opioid drug-related maxillofacial trauma: a 10-year review of a state-wide database of all hospitals admissions","authors":"Vincent Tran BDS, Michael Qiu BDS MBBS FRACDS (OMS), Santosh Kumar Tadakamadla PhD BDS MDS PGD-HP FHEA MRACDS (DPH), Kai Lee PhD BDSc MBBS MMedSc FRACDS (OMS)","doi":"10.1016/j.oooo.2024.07.013","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.07.013","url":null,"abstract":"The aim of this study was to investigate the characteristics of illicit cocaine and opioid drug-related facial trauma and determine whether the presence of cocaine or opioid drug use in facial trauma patients influenced the cause of injury, morbidity, or management. A retrospective observational cohort study was performed using records from a state-wide database of all patients who presented to a Victorian hospital with a facial fracture between 2004 and 2014. Data collected included demographics, concomitant opioid and cocaine use, mechanism of injury, facial injuries, and management. Statistical analysis was done using chi-square test, Student's tests, binary logistic regression analysis, and multivariable linear regression analysis. Results were considered statistically significant if < .05. A total of 54,613 patient presentations for facial trauma were analyzed with 363 patients in the cocaine and opioid-related group, and 54,250 patients in the nondrug-related group. Patients with illicit drug use were more likely to have facial fractures caused by interpersonal violence when compared with nondrug users (47.9% vs 23.5%, OR = 2.23, < .001). Opioid and cocaine users had 0.3 more total fractures per presentation, which included more midface and skull fractures, and more facial lacerations ( < .001). There was no statistically significant difference in the need for surgical management between the two groups. Opioid and cocaine affected patients also on average had a longer hospital stay of 3.4 days and required 0.9 more allied health inputs during their admission when compared with nondrug users ( < .05). This effect was similarly reflected when controlling for confounding variables ( < .001). Concomitant cocaine or opioid use in facial trauma patients leads to more violence-related injuries with higher morbidity and healthcare costs.","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Silva, Gustavo Borba Dias, Emily Ricelly da Silva Oliveira, Débora Frota Colares, Rodrigo Porpino Mafra, É. D. da Silveira, M. Miguel
{"title":"IMMUNOEXPRESSION OF HSP27 IN DENTIGEROUS CYSTS AND ODONTOGENIC KERATOCYSTS.","authors":"N. Silva, Gustavo Borba Dias, Emily Ricelly da Silva Oliveira, Débora Frota Colares, Rodrigo Porpino Mafra, É. D. da Silveira, M. Miguel","doi":"10.1016/j.oooo.2023.12.653","DOIUrl":"https://doi.org/10.1016/j.oooo.2023.12.653","url":null,"abstract":"","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141410046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Bezerra, Ana Luiza Oliveira Corrêa Roza, V. Cruz, W. V. van Heerden, M. Romañach, P. Vargas, D. Perez
{"title":"CLINICOPATHOLOGICAL ANALYSIS OF CALCIFYING ODONTOGENIC CYSTS: A MULTICENTER RETROSPECTIVE STUDY.","authors":"H. Bezerra, Ana Luiza Oliveira Corrêa Roza, V. Cruz, W. V. van Heerden, M. Romañach, P. Vargas, D. Perez","doi":"10.1016/j.oooo.2023.12.712","DOIUrl":"https://doi.org/10.1016/j.oooo.2023.12.712","url":null,"abstract":"","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"31 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141404183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcos Altyeres Coelho Vasconcelos, A. R. de Camargo, L. J. Grando, Marcos Phelipe Araújo Andrade Alves, Everton Thiago Luz, Maria Victória Feijó Echevenguá, M. Lisboa
{"title":"THE ROLE OF THE DENTIST IN THE HOSPITAL IN DIAGNOSIS AND MANAGEMENT OF HEMATOLOGICALLY BASED DISORDERS.","authors":"Marcos Altyeres Coelho Vasconcelos, A. R. de Camargo, L. J. Grando, Marcos Phelipe Araújo Andrade Alves, Everton Thiago Luz, Maria Victória Feijó Echevenguá, M. Lisboa","doi":"10.1016/j.oooo.2023.12.471","DOIUrl":"https://doi.org/10.1016/j.oooo.2023.12.471","url":null,"abstract":"","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"28 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141403931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ludmilla Dos Reis Silva, Anna Torrezani, Wigney Júnior Carvalho Gonzaga, Belmiro Ferreira Neves Neto, Winicius Arildo Ferreira Araujo, Vinícius Gonçalves de Souza, Carla Silva Siqueira Miranda
{"title":"IMMUNOTHERAPY WITH NATURAL COMPOUNDS IN HEAD AND NECK CANCER: A LITERATURE REVIEW.","authors":"Ludmilla Dos Reis Silva, Anna Torrezani, Wigney Júnior Carvalho Gonzaga, Belmiro Ferreira Neves Neto, Winicius Arildo Ferreira Araujo, Vinícius Gonçalves de Souza, Carla Silva Siqueira Miranda","doi":"10.1016/j.oooo.2023.12.742","DOIUrl":"https://doi.org/10.1016/j.oooo.2023.12.742","url":null,"abstract":"","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"43 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141406645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}