Hitite journal of science and engineering最新文献

Investigation of Deep Learning Approaches for Identification of Important Wheat Pests in Central Anatolia 中部安纳托利亚地区小麦重要害虫识别的深度学习方法研究

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000314

Tolga HAYIT, Sadık Eren KÖSE

引用次数: 0

Cobalt boride (Co2B) particle synthesis by one-step carbothermic reduction 一步碳热还原合成硼化钴(Co2B)颗粒

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000311

Levent KARTAL

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Energy, Exergy, and Environment Performance Evaluation of Cascade Refrigeration System with Natural Refrigerants 天然制冷剂梯级制冷系统的能源、能源和环境性能评价

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000313

Meltem KOŞAN

引用次数: 0

Electrochemical Dopamine Detection Using Palladium/Carbon Nano Onion Hybrids 钯/碳纳米洋葱杂化物电化学检测多巴胺

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000308

Hasan Hüseyin IPEKCI

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Nanoscale Liposome Synthesis for Drug Delivery Applications via Ultrafast Acoustofluidic Micromixing 利用超快声流微混合技术合成纳米级脂质体用于药物递送

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000312

Ali POURABDOLLAH VARDİN, Gurkan YESILOZ

{"title":"Nanoscale Liposome Synthesis for Drug Delivery Applications via Ultrafast Acoustofluidic Micromixing","authors":"Ali POURABDOLLAH VARDİN, Gurkan YESILOZ","doi":"10.17350/hjse19030000312","DOIUrl":"https://doi.org/10.17350/hjse19030000312","url":null,"abstract":"Nowadays, lipid nanoparticles have gained profound interest in chemical and biomedical engineering. The rapid development of therapeutic nanosystems has led to a need to design suitable approaches to synthesize bio-carriers for efficient drug delivery. Microfluidic methods provide an excellent opportunity to acquire desirable nanoparticle properties, including stability, size, shape, and size distribution, which are often challenging to obtain using conventional bulk synthesis methods. Rapid mixing is a crucial factor in the nanoprecipitation process as it influences the size and size distribution of the nanoparticles. Within this regard, in this work, we report an ultrafast acoustofluidic micromixer to synthesize liposome nanoparticles, which have been widely investigated in the literature as drug carriers due to their biocompatibility and biodegradability. This research has also investigated the influence of glycerol addition to the solvent to control the size of the liposomes. Our findings indicate that utilizing the acoustofluidic platform resulted in the production of nanoscale liposomes with small mean sizes compared to the hydrodynamic flow-focusing (HFF) method. Furthermore, the inclusion of glycerol led to a significant reduction in liposome size. These results emphasize the potential of the proposed approach for the efficient and precise synthesis of liposome nanoparticles with improved characteristics, which can be utilized in various biomedical and drug delivery applications.","PeriodicalId":500702,"journal":{"name":"Hitite journal of science and engineering","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136341365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the blind denoising efficiency of image denoising algorithms through robustness, image quality and computational burden 从鲁棒性、图像质量和计算量等方面研究图像去噪算法的盲去噪效率

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000315

Kenan GENÇOL

引用次数: 0

Use of heat-killed Aspergillus ochraceus NRRL 3174 discs as biosorbent for petroleum removal 热杀赭曲霉NRRL 3174圆盘作为生物吸附剂去除石油

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000310

Nermin Hande AVCİOGLU, Sezen BILEN OZYUREK, Işıl SEYİS BİLKAY

{"title":"Use of heat-killed Aspergillus ochraceus NRRL 3174 discs as biosorbent for petroleum removal","authors":"Nermin Hande AVCİOGLU, Sezen BILEN OZYUREK, Işıl SEYİS BİLKAY","doi":"10.17350/hjse19030000310","DOIUrl":"https://doi.org/10.17350/hjse19030000310","url":null,"abstract":"The purpose of this work was to evaluate the petroleum sorption capacity of heat-killed fungal discs obtained from Aspergillus ochraceus strain. Effect of various parameters such as biosorbent dose (0.5g-2.5g/100mL), petroleum concentration (0.5-5%), pH (4.0-8.0), contact time (1-12h) and re-usability of biosorbent (1-6) were investigated. Accordingly, the highest biosorption capacity was obtained with 1% petroleum concentration, 1.5 g/100mL heat-killed fungal discs, 10h contact time at pH: 5.0 and room temperature. Additionally, each disc was able to actively use for at least 6 more cycles in biosorption experiments. The specific removal rate was calculated as 0.114 day−1, the rate constant and half-life period were also 1.609 day-1, t1/2 = 0.431, respectively. The kinetic study was described by the pseudo-second order model and the equilibrium modeling was found to be well fitted with Langmuir isotherm. The biosorbent(s) were characterized by Focused Ion Beam Scanning Electron Microscopy (FIB-SEM). Over 80% removal of long-chain n-alkanes by the heat-killed fungal discs was confirmed by GC-MS analysis. Since there has been no similar study investigating the sorption of petroleum with heat-killed Aspergillus ochraceous discs, this novel bio-based sorbent with its low cost, environmentally friendly and easy-to-apply properties can be used in advanced biosorption studies.","PeriodicalId":500702,"journal":{"name":"Hitite journal of science and engineering","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

INTERACTION OF GHK TRIPEPTIDE WITH RECEPTORS TARGETED IN SOME CANCER STUDIES: A THEORETICAL APPROACH WITH MOLECULAR DOCKING GHK三肽与某些癌症研究中靶向受体的相互作用:一种分子对接的理论方法

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000309

Bilge BIÇAK, Serda Kecel GUNDUZ

{"title":"INTERACTION OF GHK TRIPEPTIDE WITH RECEPTORS TARGETED IN SOME CANCER STUDIES: A THEORETICAL APPROACH WITH MOLECULAR DOCKING","authors":"Bilge BIÇAK, Serda Kecel GUNDUZ","doi":"10.17350/hjse19030000309","DOIUrl":"https://doi.org/10.17350/hjse19030000309","url":null,"abstract":"Cancer, defined as the uncontrolled growth and proliferation of cells, is a serious disease seen in many people around the world. For this reason, a lot of work has been done and continues to be done by scientists for the diagnosis and treatment of cancer. It is known that various receptors are targeted in studies on cancers. In this study, ER, PR, EGFR and HER2 receptors, which are among the most frequently used target receptors, were selected. GHK is a tripeptide that has important benefits such as increasing cancer resistance and reversing cancer cells. In this study, the complex structures formed by the most commonly used target receptors (ER, PR, EGFR and HER2) and the GHK tripeptide were examined. These complex structures were obtained by molecular docking method that is a molecular modeling method used to predict how a receptor interacts with small molecules. As a result of the study, binding affinities, close interactions, and interaction types of GHK and receptors were determined, and interaction profiles with various drugs (such as tamoxifen, erlotinib and neratinib) in the literature were examined comparatively. In the light of the findings obtained in the studies, it was determined that the GHK tripeptide gave similar interaction profiles with the drugs used in cancer treatment.","PeriodicalId":500702,"journal":{"name":"Hitite journal of science and engineering","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Rubrene Concentration on Dielectric Parameters of Nematic Liquid Crystal Rubrene浓度对向列液晶介电参数的影响

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000307

Gülsüm KOCAKÜLAH

{"title":"The Role of Rubrene Concentration on Dielectric Parameters of Nematic Liquid Crystal","authors":"Gülsüm KOCAKÜLAH","doi":"10.17350/hjse19030000307","DOIUrl":"https://doi.org/10.17350/hjse19030000307","url":null,"abstract":"In this study, the dielectric parameters of E7 coded nematic liquid crystal (NLC) composites containing the different amounts of rubrene fluorescent dye were investigated. E7, E7+0.5 wt.% Rubrene, and E7+1.0 wt.% Rubrene samples were prepared. Frequency dependent dielectric constants (ɛ′ and ɛ′′), dielectric anisotropy (Δε′), and ac conductivity (σac) graphs of rubrene doped E7 NLC composites were obtained by dielectric spectroscopy method and compared with pure E7 NLC. By using these graphs, relaxation frequency (fR), relaxation time (τR), dielectric strength (δɛ′), and crossover frequency (fc) parameters of the E7 NLC and its rubrene doped composites were determined. An increase in fR from 3.045 MHz to 3.697 MHz for 0 V and from 627 kHz to 686 kHz for 40 V was observed with increasing rubrene concentration. On the other hand, a decrease in τR from 0.052 μs to 0.043 μs for 0 V and from 0.254 μs to 0.232 μs for 40 V was seen with increasing rubrene concentration. Furthermore, an increase in fc from 1.145 MHz to 1.298 MHz was obtained with increasing rubrene concentration. The results show that the dielectric parameters change with the concentration of rubrene and it is thought that this study will provide a basis for investigating the dielectric properties of rubrene doped NLC composites. Moreover, it is concluded that the produced composites are a suitable base material for electro-optical device applications such as smart displays, photonics and electrical circuit elements.","PeriodicalId":500702,"journal":{"name":"Hitite journal of science and engineering","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous effect of welding current with post-weld T6 heat-treatment on corrosion susceptibility of Al6013 alloy joined by GTAW 焊接电流与焊后T6热处理对GTAW连接Al6013合金腐蚀敏感性的影响

Hitite journal of science and engineering Pub Date : 2023-09-30 DOI: 10.17350/hjse19030000316

Mehmet TOPUZ

{"title":"Simultaneous effect of welding current with post-weld T6 heat-treatment on corrosion susceptibility of Al6013 alloy joined by GTAW","authors":"Mehmet TOPUZ","doi":"10.17350/hjse19030000316","DOIUrl":"https://doi.org/10.17350/hjse19030000316","url":null,"abstract":"Al6013 base metals were joined successfully with ER4047 weld metal by using the GTAW method under different welding currents. Post-weld T6 heat treatment effects on corrosion properties were investigated in terms of open circuit potential (OCP), potentiodynamic polarization (PDS), and electrochemical impedance spectroscopy (EIS) tests. It was determined that corrosion resistance of the post-weld samples increased with increasing welding current, while T6 heat-treatment only effective on 110A and 140A welding current samples (3.61 to 2.08, 2.95 to 2.40, and 1.38 to 2.15 µA·cm-2 for 110, 140, and 170A welding current before and after T6 heat-treatment). The characteristics of the oxide films on the surfaces are revealed with EIS analysis by a two-constant equivalent circuit model which observed that while the passive film originating from Al is formed on the surfaces, on the other hand, it contains a pittings on the surface. It was determined that the pitting resistance of the T6 heat-treated 110A samples increased (3075 to 4562 Ω). Post-corrosion SEM surface morphologies showed that low welding currents lead to more damage with increased exposure to corrosion.","PeriodicalId":500702,"journal":{"name":"Hitite journal of science and engineering","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0