Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery最新文献

{"title":"Prevalence of Nasal Obstruction in Patients with Primary Muscle Tension Dysphonia: A Pilot Study.","authors":"Abdul-Latif Hamdan, Jad Hosri, Nadine El Hadi, Lana Ghzayel, Mounir Bou Saab, Zeina Maria Semaan, Elie Alam, Maher Kasti","doi":"10.1159/000543238","DOIUrl":"https://doi.org/10.1159/000543238","url":null,"abstract":"<p><strong>Introduction: </strong>The link between nasal obstruction and muscle tension dysphonia (MTD) has not been previously investigated despite the well-established relationship between respiratory diseases and voice disorders.</p><p><strong>Methods: </strong>Patients presenting to the Voice and Swallowing Unit at a tertiary referral center between July 2022 and October 2023, and diagnosed with primary MTD were recruited. The prevalence and severity of nasal obstruction was assessed using the Visual Analogue Scale (VAS) and sinonasal symptoms were assessed using the Sinonasal Outcome Test-22 (SNOT-22) questionnaire. A group matched by age and gender, with no history of dysphonia and normal laryngeal examination was recruited as a control group.</p><p><strong>Results: </strong>A total of 65 patients were enrolled in this study. These were divided into a study group of 31 patients diagnosed with primary MTD and a control group of 34 subjects with no history of dysphonia and normal laryngeal examination. Using the VAS scale for nasal obstruction, 19 patients of the study group (61.3%) had a score above 4 and were found to have moderate to severe nasal obstruction compared to only five in the control group (14.7%) (p<0.001). Using the SNOT-22 questionnaire, 61.3% of patients with MTD had moderate to severe sinonasal symptoms as compared to only 5.9% of the control group (p<0.001).</p><p><strong>Conclusion: </strong>Patients with primary MTD are more likely to have nasal obstruction and sinonasal symptoms in comparison to patients with no dysphonia and a normal laryngeal examination.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influential Factors on Survival in Laryngeal Cancer and Treatment Modalities Comparison.","authors":"Cher Pin So, Yura Shin, Vaishnevy Ganesh, Jaiganesh Jai Manickavasagam, Richard Casasola","doi":"10.1159/000543445","DOIUrl":"10.1159/000543445","url":null,"abstract":"<p><strong>Introduction: </strong>Laryngeal cancer (LC) is the most common malignancy in otolaryngology, comprising 30-40% of head and neck malignancies. With an increasing incidence worldwide over the past few decades, LC has resulted in substantial strain on the NHS. There have been notable advancements in the treatment of LC over the years, particularly with the adoption of non-surgical methods, which emerged after the 1991 study conducted by the Veterans Affairs. Nevertheless, there has been an increase in mortality rates for head and neck cancer by approximately 15% in the UK over the last decade. This study aimed to evaluate the survival outcomes of patients with LC in our population, considering both the disease stage and treatment modality applied.</p><p><strong>Methods: </strong>Retrospective data were collected from 2015 to 2019 for all patients who were diagnosed with primary LC at NHS Tayside. Univariate and multivariate analyses were performed to determine the factors associated with overall survival (OS) and disease-specific survival (DSS) in LC. Survival analysis using Kaplan-Meier curve was used to compare the treatment modalities in different stages of LC.</p><p><strong>Results: </strong>Patients with advanced LC (stages 3 and 4) had more than 5 times risk of mortality compared to patients with early LC (stage 1 and 2) (DSS: HR 6.10, 95% CI: 1.52-14.61, p = 0.016; OS: HR 5.52, 95% CI: 1.64-13.34, p = 0.017). In patients with stage 4 LC, laryngectomy provides better survival outcomes than chemoradiotherapy (DSS: p = 0.035; OS: p = 0.046). In addition, DSS was double, and OS was 3 times higher for patients who received adjuvant radiotherapy following laryngectomy compared to patients who underwent laryngectomy alone (DSS: p = 0.036; OS: p = 0.032).</p><p><strong>Conclusion: </strong>Our study supports that surgical treatment with adjuvant radiotherapy improves the survival outcomes of advanced LC and should be considered as first-line treatment in patients who are fit for surgery. More prospective studies are needed to determine the optimal treatment approach for advanced LC with consideration of organ function, patient quality of life, and treatment-related morbidity and mortality.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"1-12"},"PeriodicalIF":1.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior Nasal Nerve Neurolysis in Addition to Radiofrequency Ablation of the Inferior Turbinates for Patients with Chronic Rhinitis.","authors":"Chien-Yu Huang, Jyun-Yi Liao, Han-Lo Teng, Bor-Hwang Kang, Yaoh-Shiang Lin, Jun-Wei Hsieh","doi":"10.1159/000543366","DOIUrl":"10.1159/000543366","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to evaluate the outcome of radiofrequency ablation of the inferior turbinates (RFITs) combined with posterior nasal nerve neurolysis (RPN3) in comparison with RFIT alone in the treatment of patients with chronic rhinitis unresponsive to pharmacological therapy.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted on adult and adolescent patients with chronic rhinitis who demonstrated a poor response to medication. Patients with a total 24-h reflective total nasal symptom score (rTNSS) of ≥5, rhinorrhea score of ≥2, and congestion score of ≥2 were included. The treatment outcomes of patients who underwent RPN3 and RFIT alone were assessed. The primary endpoint was the change from baseline in 24-h rTNSS, Nasal Obstruction Symptom Evaluation (NOSE) scores, and the response rate defined as rTNSS improved by ≧30% during follow-ups.</p><p><strong>Results: </strong>A total of 64 patients were included (45 males, 70.3%). Overall, 49 patients underwent RPN3, and 15 patients underwent RFIT alone. The rTNSS had improved by 78.4% and 65.8% in RPN3 and RFIT groups, respectively (both p < 0.001). The NOSE score had improved by 92.89% and 86.81% in the RPN3 and RFIT groups (both p < 0.001), respectively. Patients in the RPN3 group demonstrated statistically significantly better results after 3 months than patients in the RFIT alone group (p < 0.05). The response rate was 98% in the RPN3 group after 3 months.</p><p><strong>Conclusions: </strong>The proposed RPN3 alleviated rhinitis symptoms, which demonstrated a high response rate with a superior symptom control rate than RFIT alone in chronic rhinitis with severe rhinorrhea and nasal congestion cases.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"191-199"},"PeriodicalIF":1.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse Events Associated with Surgically Implanted Temporomandibular Joint Devices.","authors":"Christian Fritz, Kimberly Wei, Jinggang Ng, Deepak Lakshmipathy, Karthik Rajasekaran","doi":"10.1159/000543243","DOIUrl":"10.1159/000543243","url":null,"abstract":"<p><strong>Introduction: </strong>Temporomandibular disorder (TMD) is a common, yet potentially debilitating syndrome that negatively impacts patient quality of life. In patients with severe variants of TMD, temporomandibular joint (TMJ) devices have been utilized to replace the joint altogether. However, the risk profile and consequent cost-benefit ratio of these devices are largely debated. This report aimed to provide further insight on the safety of surgically implanted TMJ devices by analyzing adverse events from the Manufacturer and User Facility Device Experience (MAUDE) database.</p><p><strong>Methods: </strong>Inclusion criteria consisted of all MAUDE reports from January 2013 to January 2023 containing the keyword \"TMJ.\" Duplicate reports, preimplantation events, reports extrapolated from published literature reviews, and those not related to TMJ implants were excluded from analysis. Adverse events were extracted, reviewed, and categorized according to complication type, management strategy, device manufacturer, causes of device malfunction, and reporting timeframe. Nonparametric χ2 and Levene's test were used to compare average values between groups with a two-tailed p value of 0.05 being considered statistically significant.</p><p><strong>Results: </strong>A total of 385 adverse event reports were reviewed. The most common complications were infection (59, 25.9%), ankylosis (57, 25.0%), and pain (33, 14.5%). The most common device failures were implant malposition (28, 39.4%), implant dislodgement (22, 31.0%), and screw osseointegration failure (11, 15.5%). Upon assessment of revision surgeries, those undertaken to address infections had the highest rate of device explantation (77%). In a separate analysis of 28 adverse events submitted directly by patients, infection was most common self-reported complication (42.9%). Comparison of device manufacturers revealed that Biomet implants had significantly more reports of pain (χ2 = 10.21, p = 0.003), whereas Stryker implants had more infections (χ2 = 29.87, p < 0.001).</p><p><strong>Conclusion: </strong>In summary, this in-depth analysis of adverse events provides a safety profile of TMJ implants. Understanding the complication types, management strategies, and outcomes according to device manufacturer may help set patient expectations and improve patient care.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Level V Metastases in Node-Positive Oral Squamous Cell Carcinoma: Beyond Level IIA and III.","authors":"Kinjal Shankar Majumdar, Vikramjit Singh Kailey, Akash Varshney, Thaduri Abhinav, Achyuth Panuganti, Shahab Ali Usmani, Pallvi Kaul, Dungala Dileep Maharaj, Abhijeet Singh, Areej Moideen, Ramesh Prasath, Nivedhan Ravichandran, Nongthombam Surjalata Devi, Abhishek Bhardwaj, Madhu Priya, Manu Malhotra","doi":"10.1159/000543140","DOIUrl":"10.1159/000543140","url":null,"abstract":"<p><strong>Introduction: </strong>Surgical management of level V in clinically node positive (cN+) oral squamous cell carcinomas (OSCCs) is controversial. The objectives of the study were to identify predictors of level V metastases in cN+ OSCC.</p><p><strong>Methods: </strong>This retrospective study is based on institutional data of operated cN+ OSCC between April 2018 and December 2022. Clinical and pathological parameters were subjected to univariate analysis. Significant parameters in univariate analysis were further subjected to multivariate analysis. A p value of less than 0.05 was considered statistically significant.</p><p><strong>Results: </strong>None of cN1 or pN1 patients had a level V metastasis. No skip metastasis to level-V was noticed. Total number of positive lymph nodes, lymph node ratio (LNR), extranodal extension, pN classification, and the presence of level II and III metastases were found to be significant predictors for level V metastases. The post hoc analysis suggested that ≥5 positive nodes, LNR >0.1, and pN3 status were independent risk factors for level V metastases.</p><p><strong>Conclusion: </strong>Selective neck dissection for N+ OSCC is feasible in the N1 neck, preferably where nodal metastases is limited to level-I only. Patients with a bulky nodal disease, particularly those with N3 neck, ≥5 positive nodes, ENE, and metastatic lymph nodes in levels II and III should be offered comprehensive neck dissection.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Olfactory Threshold Test Results and Limits of Olfactory Testing in Patients with Parosmia.","authors":"Masayoshi Tei, Eri Mori, Rumi Sekine, Yuji Kishimoto, Hirotaka Tanaka, Monami Nagai, Yuka Tsurumoto, Nobuyoshi Otori","doi":"10.1159/000542857","DOIUrl":"10.1159/000542857","url":null,"abstract":"<p><strong>Introduction: </strong>Parosmia poses a clinical challenge due to a lack of established testing methods, leading to underestimated self-reported symptoms. This study investigated olfactory threshold trends, aiming to highlight parosmia prevalence, analyze threshold patterns, and assess diagnostic potential in current olfactory testing.</p><p><strong>Methods: </strong>A total of 407 patients who visited our olfactory clinic from April 2009 to September 2015 were categorized into parosmia and non-parosmia groups based on initial visit questionnaires. The Jet Stream T&amp;T Olfactometer measured olfactory thresholds, including mean detection and recognition thresholds, and the left-right detection threshold difference. Patient characteristics such as gender, age, time from symptom onset to hospital visit, and smoking status were compared. The study also aimed to diagnose parosmia with olfactory identification ability tests such as Open Essence and the gap between T&amp;T detection and recognition thresholds.</p><p><strong>Results: </strong>Parosmia prevalence was 18%, with a significant gender difference and a shorter onset-to-visit duration in the parosmia group. Post-traumatic and post-infectious olfactory dysfunctions exhibited higher parosmia prevalence. Olfactory threshold testing revealed significantly lower average detection (p = 0.014) and recognition (p = 0.005) thresholds in the parosmia group, with a left-right difference in detection thresholds (p = 0.012). No significant differences were found in identification ability tests. Results suggest that preserved sense of smell is crucial for perceiving parosmia symptoms.</p><p><strong>Conclusion: </strong>Parosmia was observed in 18% of patients, more commonly among females and often following trauma or infection. It presents diagnostic challenges as patients tend to maintain olfactory thresholds, making subjective assessments essential for diagnosis. The significant left-right differences in detection thresholds suggest that olfactory lateralization may play a role in the manifestation of parosmia symptoms. Our findings suggest that a unilateral occlusion test, which identifies which nostril is more likely to cause parosmia, could allow for more targeted treatment.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facial Filler Injections: Questions Patients Ask and Where They Find Answers.","authors":"Stylianos Monos, Christian Fritz, Beatrice Go, Karthik Rajasekaran","doi":"10.1159/000541497","DOIUrl":"10.1159/000541497","url":null,"abstract":"<p><strong>Introduction: </strong>The most pressing questions patients ask about facial fillers and the sources to which patients are directed remain incompletely understood.</p><p><strong>Methods: </strong>The search engine optimization tool Ahrefs was utilized to extract Google metadata on searches performed in the USA. The most frequently asked questions were categorized by topic, while websites were categorized by authoring organization. JAMA benchmark criteria were used for website information quality assessment.</p><p><strong>Results: </strong>A total of 300 questions for the term \"fillers\" were extracted. The majority of search queries (24.0%) and monthly search volume (39.3%) pertained to procedural costs. The mean JAMA score for private practice sources (1.1 ± 0.57) was significantly lower than that of corporate sources (2.6 ± 0.55, p = 0.0003) but not significantly lower than academic pages (1.6 ± 1.34, p = 0.483). With respect to monthly search volume, queries concerning lip fillers have been increasingly asked at a rate that exceeds other injection sites.</p><p><strong>Conclusion: </strong>Online searches for facial fillers often involve the topic of cost and frequently direct patients to websites that contain inadequate information on authorship, attribution, disclosure, and currency. When compared to other anatomic sites, search queries involving lip fillers have increased over the last 3 years.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Olfactory Carcinoma, Similar yet Distinct to Olfactory Neuroblastoma: A Case Report and Literature Review.","authors":"Mohammad Bilal Alsavaf, Basit Jawad, Eman H Salem, Kittichai Mongkolkul, Abberly Lott Limbach, Daniel M Prevedello, Ricardo Carrau","doi":"10.1159/000541170","DOIUrl":"10.1159/000541170","url":null,"abstract":"<p><strong>Introduction: </strong>Olfactory carcinoma (OC) is a rare tumor that is often misdiagnosed as olfactory neuroblastoma (ONB). Due to its rarity, there is no established standard treatment for OC, and there have been no reports of successful long-term follow-up treatment yet.</p><p><strong>Case presentation: </strong>Two male patients, aged 54 and 48 years, presented with similar symptoms of nasal obstruction, anosmia, facial swelling, and epistaxis. Imaging in both cases revealed large, locally advanced sinonasal neoplasms. Initial biopsies were concerning for ONB; however, final pathological analyses confirmed high-grade OC. Treatment comprised induction chemotherapy, extensive skull base tumor resection, adjuvant chemoradiotherapy, and reconstructive surgery in both cases. The 54-year-old remains disease-free at 7 years, while the 48-year-old demonstrates no evidence of disease at 8 months.</p><p><strong>Conclusion: </strong>Accurate diagnostic differentiation is imperative to optimize a treatment approach. Although outcomes with OC tend to be worse than those of ONB, effective control can be achieved with judicious concurrent use of neoadjuvant, surgery, and adjuvant treatments. Ongoing surveillance, biobanking, and genomic analysis are crucial to gain a better understanding of this complex disease.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"1-6"},"PeriodicalIF":1.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiotherapy-Related Quality of Life in Nasopharyngeal Carcinoma Patients: A Systematic Review and Meta-Analysis.","authors":"Kai Chen, Yuan Cai, Luyun Jiang, Li Tian","doi":"10.1159/000541124","DOIUrl":"10.1159/000541124","url":null,"abstract":"<p><strong>Introduction: </strong>This systematic review and meta-analysis evaluated the quality of life (QoL) for nasopharyngeal carcinoma (NPC) patients with radiotherapy.</p><p><strong>Methods: </strong>A systematic literature search was performed to identify relevant studies published until March 2022. Quality evaluation and data extraction were performed for the included studies, and meta-analysis was performed using Stata.</p><p><strong>Results: </strong>Nine studies, including 1,659 patients, were eligible. Most QoL scales developed at the end of the treatment course and then followed by a gradual recovery to 1 year and more than 1 year after treatment. However, some items have not changed significantly and have a deteriorating trend. Items of cognitive functioning and constipation in EORTC QLQ-C30, and sexuality, felt ill, and weight gain in EORTC QLQ-H&amp;N35 showed that scales with follow-up of more than 1 year were worse than those within 1 year but still better than those after treatment. In the intensity-modulated radiotherapy (IMRT) subgroup in EORTC QLQ-C30, cognitive functioning was similar to those before, and there was no significant change in insomnia. There was no significant change in the teeth item in EORTC QLQ-H&amp;N35. In the IMRT subgroup, scales of swallowing, felt ill, and weight gain with follow-up of more than 1 year were worse than those within 1 year.</p><p><strong>Conclusion: </strong>The QoL of patients with NPC is significantly impaired after radiotherapy-treated compared to baseline, and most of these items will gradually improve.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Magnetic Resonance Imaging in Paranasal Mucocele with Visual Disturbance.","authors":"Haruo Yoshida, Fujinobu Tanaka, Kenji So, Yoshihiko Kumai","doi":"10.1159/000539891","DOIUrl":"10.1159/000539891","url":null,"abstract":"<p><strong>Introduction: </strong>Ocular imaging strategies have evolved to facilitate the diagnosis of optic neuropathy. This study aimed to evaluate the pathogenesis of visual disturbance associated with paranasal mucocele via magnetic resonance imaging (MRI).</p><p><strong>Methods: </strong>A total of 19 patients with mucocele and visual disturbance who underwent endoscopic sinus surgery, orbital MRI, and sinus computed tomography were included. The age, sex, days from onset to surgery, eye pain, and imaging findings were analyzed. The results were compared between two groups: 7 patients with preoperative visual acuity worse than 20/200 (the poor group) and 12 patients with equal or better than 20/200 (the fair group).</p><p><strong>Results: </strong>Imaging showed a high compression rate of the orbit in 17 (89.5%) and enlargement of the subarachnoid space around the optic nerve in 15 (78.9%) of 19 patients. Preoperative vision was significantly poor in cases with hyperintense regions in the optic nerve on T2-weighted imaging, indicating the presence of optic neuritis. No cases showed severe inflammation of the cyst or the presence of intraorbital fat tissue.</p><p><strong>Conclusion: </strong>MRI-based diagnosis proved useful in evaluating pathological factors, such as orbital compression, ischemia, and optic neuritis, in individual cases. It can help in gaining insight into the pathogenesis and developing appropriate treatment strategies for visual disturbances associated with paranasal mucocele.</p>","PeriodicalId":49717,"journal":{"name":"Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery","volume":" ","pages":"132-139"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}