Postepy W Kardiologii Interwencyjnej最新文献

{"title":"The role of aortic valve area in the quantitative flow ratio-fractional flow reserve discrepancy in patients with coronary artery disease and severe aortic stenosis.","authors":"Artur Dziewierz, Łukasz Rzeszutko, Łukasz Niewiara, Jacek Legutko, Paweł Kleczyński","doi":"10.5114/aic.2025.148118","DOIUrl":"10.5114/aic.2025.148118","url":null,"abstract":"<p><strong>Introduction: </strong>The accuracy of fractional flow reserve (FFR) and quantitative flow ratio (QFR) in assessing coronary artery disease in severe aortic stenosis (AS) patients may be affected by the severity of AS.</p><p><strong>Aim: </strong>We investigated the relationship between aortic valve area (AVA) and the diagnostic performance of QFR in this context.</p><p><strong>Material and methods: </strong>We analyzed 416 intermediate coronary lesions in 221 severe AS patients using FFR and QFR, categorizing them based on AVA into two groups: AVA < 0.5 cm² and AVA ≥ 0.5 cm².</p><p><strong>Results: </strong>In all, 47 (21.2%) patients had an AVA < 0.5 cm². The median FFR and QFR values were comparable between groups, with a high agreement rate: interclass coefficient of 0.96 (95% CI: 0.94 to 0.97) for AVA < 0.5 cm² and 0.97 (95% CI: 0.97 to 0.98) for AVA ≥ 0.5 cm². Concordance in detecting significant ischemia was 96.3% for AVA ≥ 0.5 cm² but dropped to 86.5% for AVA < 0.5 cm², with discrepancies mainly in cases where FFR was negative and QFR positive. Multivariable analysis showed AVA and %DS as independent predictors of discordance; AVA ≥ 0.5 cm² had an OR of 0.229 (95% CI: 0.095 to 0.548; <i>p</i> < 0.001), and each 1% increase in %DS increased the odds by 1.070 (95% CI: 1.034 to 1.107; <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>In severe AS, QFR closely correlates with FFR. However, patients with AVA < 0.5 cm² might exhibit a higher incidence of false-positive ischemia detection by QFR.</p>","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"80-87"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for cerebral artery stenosis in patients with minor ischemic stroke classified as large atherosclerosis.","authors":"Yu Xia, Xia Zhou, Han Liu, Bo Tian, Rui Zhu, Zhongwu Sun","doi":"10.5114/aic.2024.147643","DOIUrl":"10.5114/aic.2024.147643","url":null,"abstract":"<p><strong>Introduction: </strong>The incidence of minor ischemic stroke (MIS) and associated cognitive impairment is rising, particularly among younger individuals. Thus, both primary and secondary prevention strategies are essential.</p><p><strong>Aim: </strong>This study investigated the risk factors for cerebral artery stenosis (CAS) in patients with MIS classified as large atherosclerosis (LAA) by TOAST, and examined the relationship between cognitive function and plasma lipoprotein-associated phospholipase A2 levels.</p><p><strong>Material and methods: </strong>We conducted a retrospective analysis of 789 MIS patients admitted to two hospitals between January 2015 and December 2023. Patients were classified using the TOAST criteria, with vascular stenosis detected via computed tomography angiography (CTA) and magnetic resonance angiography (MRA). Cognitive function was assessed using the Mini-Mental State Examination (MMSE). Univariate and multivariate regression analyses were performed to identify risk factors for CAS among LAA-type MIS patients.</p><p><strong>Results: </strong>Among the 789 patients, 494 (62.61%) had LAA. A total of 377 (76.32%) patients exhibited LAA-type vascular stenosis. Significant risk factors for CAS included a history of hypertension, diabetes, ischemic stroke, elevated fasting blood glucose, and plasma lipoprotein-associated phospholipase 2 levels (<i>p</i> < 0.05). Multivariate analysis revealed hypertension and increased phospholipase A2 as independent risk factors (OR = 2.046, OR = 1.059). The area under the ROC curve for plasma lipoprotein-associated phospholipase A2 predicting CAS was 0.700 (<i>p</i> < 0.0001). Additionally, a negative correlation was found between plasma lipoprotein-associated phospholipase A2 levels and MMSE scores (<i>r</i> = -0.218, <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>LAA is the predominant cause of MIS, with high rates of vascular stenosis. Hypertension and elevated plasma lipoprotein-associated phospholipase A2 levels are significant independent risk factors for CAS, and increased plasma lipoprotein-associated phospholipase A2 correlates negatively with cognitive function.</p>","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"94-100"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter aortic valve implantation with the ACURATE Prime device: initial Polish experience.","authors":"Jarosław Trębacz, Robert Sobczyński, Maciej Stąpór, Michał T Okarski, Jacek Legutko, Paweł Kleczyński","doi":"10.5114/aic.2025.148008","DOIUrl":"10.5114/aic.2025.148008","url":null,"abstract":"","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"129-130"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant left main coronary artery to right atrium fistula: an extremely rare cause of fainting and palpitations.","authors":"Milenko Rosic, Ranko Zdravkovic, Miodrag Golubovic, Nikola Komazec, Strahinja Mrvic, Vesna Rosic","doi":"10.5114/aic.2025.148004","DOIUrl":"10.5114/aic.2025.148004","url":null,"abstract":"","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"125-126"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elevated oxidative stress markers as independent predictors of isolated coronary artery ectasia.","authors":"Sadettin S Baysal, Şahbender Koç, Kerem Özbek, Muzaffer Bayhatun","doi":"10.5114/aic.2025.148148","DOIUrl":"10.5114/aic.2025.148148","url":null,"abstract":"<p><strong>Introduction: </strong>Coronary artery ectasia (CAE) is a vascular anomaly characterized by abnormal coronary artery dilation, often associated with endothelial dysfunction and inflammation. While CAE shares features with coronary artery disease (CAD), its independent pathophysiology remains unclear, particularly in cases without concurrent CAD.</p><p><strong>Aim: </strong>To evaluate oxidative and antioxidant biomarker levels in patients with isolated CAE to understand their role in its pathogenesis.</p><p><strong>Material and methods: </strong>Our study was conducted involving 48 patients with isolated CAE and 32 controls with normal coronary angiograms. Oxidative stress markers, including total oxidative status (TOS), oxidative stress index (OSI), and lipid hydroperoxide (LOOH), were measured, alongside antioxidant markers such as paraoxonase-1 (PON1), ceruloplasmin (CP), free sulfhydryl (SH) groups, and total antioxidant status (TAS).</p><p><strong>Results: </strong>CAE patients exhibited significantly higher levels of TOS (30.14 ±8.81 vs. 23.88 ±4.74 mmol H₂O₂ equiv./l, <i>p</i> = 0.004), OSI (3.21 ±1.12 vs. 2.43 ±0.53 arbitrary units, <i>p</i> < 0.001), and LOOH (11.95 ±2.88 vs. 10.13 ±1.66 µmol H₂O₂ equiv./l, <i>p</i> = 0.003). No significant differences were found in TAS, PON1, CP, or SH levels between groups (<i>p</i> > 0.05 for all). Logistic regression identified smoking, TOS, and high sensitivity C-reactive protein (hsCRP) as independent predictors of CAE.</p><p><strong>Conclusions: </strong>Elevated oxidative stress markers, particularly TOS, OSI, and LOOH, indicate a heightened pro-oxidant state in CAE, while antioxidant defenses remain largely unaltered. These findings suggest that oxidative stress may contribute to CAE pathogenesis, emphasizing the need for therapies targeting oxidative imbalance.</p>","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"67-72"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of nicorandil compared to placebo on cardiac outcomes of patients with ST-elevation myocardial infarction undergoing percutaneous coronary intervention: a meta-analysis.","authors":"Mingying Gu, Tingting Xu","doi":"10.5114/aic.2025.148175","DOIUrl":"10.5114/aic.2025.148175","url":null,"abstract":"<p><strong>Introduction: </strong>Nicorandil (2-nicotinamidoethyl-nitrate ester) is an ATP-sensitive potassium channel opener with the ability to donate nitric oxide (NO), which can increase coronary blood flow, particularly at the microcirculation level. Recent clinical trials have reported that nicorandil treatment during percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) patients can modulate their clinical outcomes; however, its effects on STEMI patients vary widely across different studies and patient subgroups.</p><p><strong>Methods: </strong>PubMed, Web of Science, Scopus, and Cochrane Library were systematically searched from inception to October 6, 2024. Due to significant heterogeneity, a random-effects model was adopted to pool data.</p><p><strong>Results: </strong>In this study, a total of 1802 participants in the control group and 1844 participants in the nicorandil group were included. Nicorandil treatment during PCI significantly decreased arrhythmia (RR = 0.52, 95% CI [0.32, 0.84], <i>I</i> ² = 23.98%), and the re-hospitalization of patients (RR = 0.56, 95% CI [0.33, 0.95], <i>I</i> ² = 0.00%); amelioration of the coronary blood flow level (RR = 1.07, 95% CI [1.01, 1.12], <i>I</i> ² = 40.90%) was observed as well. Other clinical outcomes such as chest pain, cardiovascular death, and heart failure showed no significant effect of nicorandil treatment during the PCI procedure.</p><p><strong>Conclusions: </strong>Intracoronary nicorandil treatment during PCI in STEMI patients can significantly impact several important clinical outcomes, such as arrhythmia, coronary blood flow rate, and re-hospitalization incidence, but does not show significant effects on chest pain, cardiovascular death, and heart failure.</p>","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"4-14"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of preprocedural pulmonary artery systolic pressure on acute kidney injury related to transcatheter aortic valve replacement.","authors":"Murat Gök, Alparslan Kurtul, Kenan Yalta, Ferudun Akkuş, Furkan Karahan, Servet Altay","doi":"10.5114/aic.2025.148178","DOIUrl":"10.5114/aic.2025.148178","url":null,"abstract":"<p><strong>Introduction: </strong>Transcatheter aortic valve replacement (TAVR) may lead to acute kidney injury (AKI), potentially associated with an unfavorable prognosis in the short and long term.</p><p><strong>Aim: </strong>The goal of this analysis was to explore the predictive potential of pulmonary artery systolic pressure (PASP) for the evolution of AKI following TAVR in an effort to more reliably establish potential risk factors for this expanding population.</p><p><strong>Material and methods: </strong>This single-center retrospective analysis included subjects (<i>n</i> = 90) with severe aortic stenosis (AS) undergoing TAVR. Subjects were categorized into two groups based on the evolution of TAVR-associated AKI. Logistic regression analysis was harnessed to determine predictors of TAVR-associated AKI.</p><p><strong>Results: </strong>The overall incidence of TAVR-associated AKI was found to be 25.6%. Regarding the baseline PASP values, the TAVR-associated AKI(+) group demonstrated higher PASP values compared with those without AKI (55.4 ±14.0 vs. 37.1 ±16.3 mm Hg, <i>p</i> < 0.001). Multivariate logistic regression analysis suggested EuroSCORE (OR = 1.238, 95% CI: 1.093-1.401, <i>p</i> = 0.001), PASP (OR = 1.076, 95% CI: 1.017-1.139, <i>p</i> = 0.011), and hypertension (OR = 3.544, 95% CI: 1.438-5.738, <i>p</i> = 0.017) as independent AKI predictors. ROC curve analysis suggested a PASP value of > 39 mm Hg as an AKI predictor in the post-TAVI setting (with specificity and sensitivity of values of 70.7% and 82.6%, respectively).</p><p><strong>Conclusions: </strong>PASP at baseline was found to be independently associated with TAVR-associated AKI evolution. In other words, a higher PASP value in the pre-TAVI setting might serve as a potential marker of AKI evolution following TAVI.</p>","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"88-93"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual reality modelling based on computed tomography and three-dimensional angiography for planning of percutaneous and hybrid treatment in infants with pulmonary vein stenosis.","authors":"Judyta Szeliga, Małgorzata Waśko, Jacek Kołcz, Andrzej Rudziński, Ryan Callahan, Sebastian Góreczny","doi":"10.5114/aic.2025.147992","DOIUrl":"10.5114/aic.2025.147992","url":null,"abstract":"","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"108-113"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to unfold a folded large-bore sheath after Impella-supported percutaneous coronary intervention.","authors":"Szymon Glanowski, Ewa Kwiatkowska, Michalina Jelonek-Harasiuk, Łukasz Niewiara, Jacek Legutko, Paweł Kleczyński","doi":"10.5114/aic.2025.148007","DOIUrl":"10.5114/aic.2025.148007","url":null,"abstract":"","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"127-128"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teaching bird species recognition may improve clinicians' ability to accurately analyse ECG recordings.","authors":"Sławomir Murawiec, Rafał Baranowski","doi":"10.5114/aic.2025.147991","DOIUrl":"10.5114/aic.2025.147991","url":null,"abstract":"","PeriodicalId":49678,"journal":{"name":"Postepy W Kardiologii Interwencyjnej","volume":"21 1","pages":"101-103"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}