Quimica Nova最新文献_第9页

DESAFIOS SUPERADOS, NOVOS COMPROMISSOS 克服挑战，新的承诺

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-03-03 DOI: 10.21577/0100-4042.20230016

Giovanna Machado, Jorge David, N. Morgon

引用次数: 0

CAFÉ COM QUIMIOMETRIA: UMA APLICAÇÃO DO PLANEJAMENTO FATORIAL FRACIONÁRIO 25-1 化学计量学咖啡:分数因子设计25-1的应用

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-03-03 DOI: 10.21577/0100-4042.20170943

K. Silva, G. Caldeira, K. Nogueira, M. Canela, P. Filgueiras, Murilo Souza

{"title":"CAFÉ COM QUIMIOMETRIA: UMA APLICAÇÃO DO PLANEJAMENTO FATORIAL FRACIONÁRIO 25-1","authors":"K. Silva, G. Caldeira, K. Nogueira, M. Canela, P. Filgueiras, Murilo Souza","doi":"10.21577/0100-4042.20170943","DOIUrl":"https://doi.org/10.21577/0100-4042.20170943","url":null,"abstract":"COFFEE WITH CHEMOMETRIC: AN APPLICATION OF 25-1 FRACTIONAL FACTORIAL DESIGN. Chemometrics is a subfield of chemistry that emerged from advances in analytical instrumentation and computing. When seeking to solve chemical problems that depend on many concomitants experimental variables, chemometrics can be employed in order to extract as much information as possible in the least possible number of experiments. In addition, it is possible to evaluate the important effects and interactions among the variables to understand the processes being monitored in each system. In this sense, this article aimed to develop a didactic experiment of caffeine extraction using an espresso machine, applying the 25-1 fractional factorial design. The variables studied were temperature (75 and 78 ºC), pressure (2 and 15 bar), granulation (bean and ground), type of coffee (special and traditional) and period of the day (morning and afternoon) to obtain maximum extraction of caffeine. The coffee extracts obtained were analyzed using UV-Vis molecular absorption spectrophotometry. The developed experiment showed the potential to spread the application of chemometrics in the academic environment and to facilitate the teaching of fractional factorial design.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68267740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

O POTENCIAL DA XANTONA NATURAL α-MANGOSTINA NO DESENVOLVIMENTO DE NOVOS AGENTES ANTI-INFECCIOSOS: UMA REVISÃO 天然α-山竹素山酮在新型抗感染药物开发中的潜力:综述

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-03-03 DOI: 10.21577/0100-4042.20170954

D. Pinto, Gabriela Lobato De Souza, Paulo Pitasse-Santos, A. Velez, Debora Decote-Ricardo, Debora Duarte Dos Santos, Leonardo Freire-de-Lima, Célio Freire-de-Lima, Marco de Lima

{"title":"O POTENCIAL DA XANTONA NATURAL α-MANGOSTINA NO DESENVOLVIMENTO DE NOVOS AGENTES ANTI-INFECCIOSOS: UMA REVISÃO","authors":"D. Pinto, Gabriela Lobato De Souza, Paulo Pitasse-Santos, A. Velez, Debora Decote-Ricardo, Debora Duarte Dos Santos, Leonardo Freire-de-Lima, Célio Freire-de-Lima, Marco de Lima","doi":"10.21577/0100-4042.20170954","DOIUrl":"https://doi.org/10.21577/0100-4042.20170954","url":null,"abstract":"THE POTENTIAL OF NATURAL XANTHONE α-MANGOSTIN IN THE DEVELOPMENT OF NOVEL ANTIINFECTIVE AGENTS: A REVIEW. The mangosteen (Garcinia mangostana, Linn.) is a tropical fruit cultivated in the tropical forests of Southeast Asian countries. It is recognized as the queen of fruits due to its unique color, aroma, and flavor. It has been used for centuries in Southeastern Asian traditional medicine for the treatment of various diseases. Many functional molecules with high medicinal value are obtained from the pericarp of mangosteen fruit, whose major constituent is xanthone α-mangostin. Several studies have been carried out over the last decades to further investigate and understand the pharmacological properties associated with the plant and its main chemical constituents, belonging to the class of xanthones. In addition, numerous in vitro and in vivo studies related to mangosteen have been published, indicating its importance and its potential application in medicinal chemistry. Prenylated xanthones, which include α-mangostin, are secondary metabolites particularly common in plants belonging to the Clusiaceae family. These substances have been intensively investigated for their potential as biologically active agents. This article describes a critical analysis of published data related to the properties of α-mangostin, aiming to provide a more detailed view of its potential as a chemotherapeutic agent for the prevention and treatment of infectious diseases.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68268412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ROOM-TEMPERATURE PPB-LEVEL ANILINE VAPOR SENSOR FUNCTIONALIZED WITH UIO-66-SO3H 以uio-66-so3h功能化的室温ppb级苯胺蒸汽传感器

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-02-01 DOI: 10.21577/0100-4042.20170958

Jun Cai, Luyu Wang, Yunling Wu

引用次数: 1

USO DA ANÁLISE BIBLIOMÉTRICA COMO FERRAMENTA PARA O LEVANTAMENTO DE ESTUDOS SOBRE A METABOLÔMICA APLICADA NA BIORREMEDIAÇÃO DE ÁREAS IMPACTADAS POR HIDROCARBONETOS 利用文献计量学分析作为调查代谢组学在碳氢化合物影响地区生物修复中的应用研究的工具

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-02-01 DOI: 10.21577/0100-4042.20170960

Bruna Natali Da Costa, Camila Dantas, Beatriz Miranda, D. Lima, Olívia Maria de Oliveira, K. Garcia, Gisele Canuto, L. Teixeira

{"title":"USO DA ANÁLISE BIBLIOMÉTRICA COMO FERRAMENTA PARA O LEVANTAMENTO DE ESTUDOS SOBRE A METABOLÔMICA APLICADA NA BIORREMEDIAÇÃO DE ÁREAS IMPACTADAS POR HIDROCARBONETOS","authors":"Bruna Natali Da Costa, Camila Dantas, Beatriz Miranda, D. Lima, Olívia Maria de Oliveira, K. Garcia, Gisele Canuto, L. Teixeira","doi":"10.21577/0100-4042.20170960","DOIUrl":"https://doi.org/10.21577/0100-4042.20170960","url":null,"abstract":"USE OF BIBLIOMETRIC ANALYSIS AS A TOOL FOR SURVEYING STUDIES ON METABOLOMICS APPLIED TO THE BIOREMEDIATION OF AREAS IMPACTED BY HYDROCARBONS. Bibliometric reviews, carried out from access to databases of scientific articles associated with software for data processing, can be helpful for qualitative and quantitative assessments of existing publications on a given topic. Several petroleum hydrocarbons are carcinogenic and immunotoxic agents, causing adverse effects on the biota, and the study of metabolites generated in bioremediation processes has been the object of current research. Therefore, in this work, the use of bibliometric analysis as a tool for surveying studies on the applied metabolomics bioremediation of areas impacted by hydrocarbons is presented. A bibliometric review was carried out in the Scopus Preview and Web of Science databases with data analysis using RStudio software with the bibliometrix package. The survey gathered the studies and prominent publications of the last seven years, making it possible to present gaps and opportunities in the area.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68268388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A GREEN AND RELIABLE TITRIMETRIC METHOD FOR TOTAL ORGANIC CARBON DETERMINATION WITH POTASSIUM PERMANGANATE 绿色可靠的高锰酸钾滴定法测定总有机碳

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-02-01 DOI: 10.21577/0100-4042.20170961

O. Lã, Caroline Sales De Azevedo, Cristina Barra, J. Netto-Ferreira, Érica de Sousa, José Rocha Jr.

{"title":"A GREEN AND RELIABLE TITRIMETRIC METHOD FOR TOTAL ORGANIC CARBON DETERMINATION WITH POTASSIUM PERMANGANATE","authors":"O. Lã, Caroline Sales De Azevedo, Cristina Barra, J. Netto-Ferreira, Érica de Sousa, José Rocha Jr.","doi":"10.21577/0100-4042.20170961","DOIUrl":"https://doi.org/10.21577/0100-4042.20170961","url":null,"abstract":"The determination of total organic carbon in soils, fertilizers, sewage sludge, sediments, and humic extracts is widely performed by chemical oxidation methods with K2Cr2O7. The Yeomans-Bremner (YB) method is currently the one that stands out the most. The drawback of these methods is the large amount of concentrated H2SO4 used, which generates a large amount of hazardous waste. This work proposes using KMnO4 as an alternative to K2Cr2O7 for a lower consumption of H2SO4. The method uses the back titration of Fe2+ added to consume both the MnO2 produced and the excess KMnO4 that was not consumed in the OM oxidation. A non-trivial and yet not explored stoichiometry was applied for this purpose, providing a success not yet achieved in using permanganate to determine TOC by titration. The ideal condition for the oxidation of OC was determined by the analysis of a potassium hydrogen phthalate standard and involved the use of 0.125 mol L-1 H2SO4 and temperature of 70 °C, obtaining a significant advantage over the YB method (concentrated H2SO4 and 170 °C). The proposed method was applied to the analysis of soil samples, producing conversion factors for soil organic carbon that varied between 0.652 and 1.12.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68268856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

SEMICARBAZONAS: SEQUÊNCIA DIDÁTICA INTERDISCIPLINAR EM AULAS EXPERIMENTAIS DE QUÍMICA ORGÂNICA E QUÍMICA MEDICINAL 氨基脲:有机化学和药物化学实验课堂的跨学科教学顺序

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-02-01 DOI: 10.21577/0100-4042.20170962

Vanessa Oliveira, I. Sá, Georgtown da Silva, V. Santos, C. Araújo, A. Gonsalves

{"title":"SEMICARBAZONAS: SEQUÊNCIA DIDÁTICA INTERDISCIPLINAR EM AULAS EXPERIMENTAIS DE QUÍMICA ORGÂNICA E QUÍMICA MEDICINAL","authors":"Vanessa Oliveira, I. Sá, Georgtown da Silva, V. Santos, C. Araújo, A. Gonsalves","doi":"10.21577/0100-4042.20170962","DOIUrl":"https://doi.org/10.21577/0100-4042.20170962","url":null,"abstract":"SEMICARBAZONES: INTERDISCIPLINARY APPROACH IN EXPERIMENTAL CLASSES OF ORGANIC CHEMISTRY AND MEDICINAL CHEMISTRY. Considering the chemical and pharmacological properties of semicarbazones, an interdisciplinary didactic sequence was developed to be applied in experimental classes of undergraduate courses in Pharmacy, Chemistry and related areas. This didactic sequence was planned in three steps, starting from the planning of the target molecule, a semicarbazone derived from helional, to its synthesis, physicochemical characterization (CCD, melting point, FTIR and UV-Vis) and in silico tests of its pharmacokinetic properties using the free software ADMETlab 2.0. The proposed target molecule has as molecular scaffold the 1,3-benzodiaxole nucleus and the semicarbazone function, aiming to obtain a molecule with promising anticonvulsant action and that can be obtained by a low cost and easy to execute methodology, which makes it attractive for use in experimental classes. Thus, the application of this didactic sequence aims to provide undergraduate students the opportunity to experience the process of drug development, applying techniques for planning, synthesis, characterization, and pharmacokinetic evaluation in silico. Besides reinforcing the interdisciplinary teaching of Medicinal Chemistry, applying in an integrated way the theoretical and practical knowledge of the disciplines of Organic Chemistry, Physical Chemistry, Pharmacology and Computational Chemistry.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68268877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AVALIAÇÃO DOS CIENTISTAS: UTILIZAMOS AS MÉTRICAS CORRETAS? 科学家评估:我们使用正确的指标了吗?

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-02-01 DOI: 10.21577/0100-4042.20170955

Josefredo Pliego Jr.

引用次数: 0

DETERMINAÇÃO DOS PARÂMETROS CINÉTICOS DE DEGRADAÇÃO E ESTIMATIVA DO TEMPO DE FALHA DE CONTRAMEDIDAS ELETRÔNICAS “FLARE” DO TIPO MAGNÉSIO TEFLON® VITON® 测定镁特氟隆®VITON®型“火炬”电子对抗装置的降解动力学参数和失效时间估计

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-02-01 DOI: 10.21577/0100-4042.20170963

Carlos Rodrigues, Edemar Kirchhof, J. Rocco

{"title":"DETERMINAÇÃO DOS PARÂMETROS CINÉTICOS DE DEGRADAÇÃO E ESTIMATIVA DO TEMPO DE FALHA DE CONTRAMEDIDAS ELETRÔNICAS “FLARE” DO TIPO MAGNÉSIO TEFLON® VITON®","authors":"Carlos Rodrigues, Edemar Kirchhof, J. Rocco","doi":"10.21577/0100-4042.20170963","DOIUrl":"https://doi.org/10.21577/0100-4042.20170963","url":null,"abstract":"DETERMINATION OF DEGRADATION KINETIC PARAMETERS AND FAILURE TIME ESTIMATION OF MAGNESIUM TEFLON® VITON® ELECTRONIC “FLARE” COUNTERMEASURES. Flare type countermeasures that use the composition designated as MTV (Magnesium, Teflon®, Viton®), are the most used by Air Forces around the world. In Brazil, these “flares” are used in several locations and are subjected to different handling, storage and operation conditions that can affect their performance and compromise their service life. In this work, the Monte Carlo method was applied to estimate an empirical model to predict the lifetime of these countermeasures, using as variables the temperature and the relative humidity of the place where the material is used. The results were analyzed using multiple linear regression and analysis of variance. The kinetic parameters of material thermal degradation, such as Activation Energy and Pre-exponential Factor, and the estimated failure times of these countermeasures were determined. The results pointed out to strong temperature influence on material degradation resulting in different lifetimes for each site studied.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68268937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ESTUDO DE GASOLINAS PREMIUM E COMUM COMERCIALIZADAS NO BRASIL ATRAVÉS DO MÉTODO ERETIC-RMN E QUIMIOMETRIA 通过ERETIC- nmr方法和化学计量学研究在巴西销售的优质和普通汽油

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-02-01 DOI: 10.21577/0100-4042.20230004

Vinícius Pinto, Gerlon Oliveira, Christian Gomides, M. Monteiro, L. Lião

{"title":"ESTUDO DE GASOLINAS PREMIUM E COMUM COMERCIALIZADAS NO BRASIL ATRAVÉS DO MÉTODO ERETIC-RMN E QUIMIOMETRIA","authors":"Vinícius Pinto, Gerlon Oliveira, Christian Gomides, M. Monteiro, L. Lião","doi":"10.21577/0100-4042.20230004","DOIUrl":"https://doi.org/10.21577/0100-4042.20230004","url":null,"abstract":"STUDY OF PREMIUM AND REGULAR GASOLINES MARKETED IN BRAZIL THROUGH THE ERETIC-NMR METHOD AND CHEMOMETRICS. Gasoline is a complex mixture of hydrocarbons whose detailed study of its chemical profiles is a challenging task. This type of product of great commercial importance has its quality measured in Brazil from classical physicalchemical tests. Although robust, physical-chemical analyses generally require large amounts of assays, solvents, and samples, in addition to not being indicated for the detection of small compositional changes. In this work, NMR and chemometrics were used in the quantitative study of different samples of gasoline with varying ratings of octane and ethanol contents. The results demonstrated the usefulness of NMR spectroscopy both to characterize as well as to distinguish the chemical profiles of regular and premium gasoline. With the application of the ERETIC, the chemical profiles mentioned were quantitatively differentiated and the proportions between hydrocarbons were determined for both types of gasoline. The application of the ERETIC was also successful in the quantitative determination of ethanol contents in regular and premium gasoline. The aforementioned method, which dispenses with the use of quantification standards inserted directly into the sample of interest, was unequivocal in accounting for the volume of ethanol, in addition to showing excellent agreement with the method currently adopted by the Brazilian government.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68269924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0