Quimica Nova最新文献_第7页

NANOSTRUCTURED CURCUMIN WITH CHOLINE AND GERANIC ACID IONIC LIQUID (CAGE-IL): POTENTIAL FOR INCORPORATION INTO PHARMACEUTICAL GEL FORMULATIONS 纳米结构姜黄素与胆碱和天竺葵酸离子液体(笼- il):合并到药物凝胶制剂的潜力

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-05-08 DOI: 10.21577/0100-4042.20230012

M. Vila, Rodrigo Boscariol, V. Balcão

{"title":"NANOSTRUCTURED CURCUMIN WITH CHOLINE AND GERANIC ACID IONIC LIQUID (CAGE-IL): POTENTIAL FOR INCORPORATION INTO PHARMACEUTICAL GEL FORMULATIONS","authors":"M. Vila, Rodrigo Boscariol, V. Balcão","doi":"10.21577/0100-4042.20230012","DOIUrl":"https://doi.org/10.21577/0100-4042.20230012","url":null,"abstract":"Curcumin, a phytochemical, exhibits several biological properties and has been studied for the treatment of psoriasis. To facilitate its transdermal permeation, permeation enhancers such as choline and geranic acid ionic liquid (CAGE-IL) have been studied. From this perspective, the research effort entertained herein aimed at developing and evaluating the stability of an emulsion prepared with curcumin (phytochemical from Curcuma longa L.) and locust bean gum (extracted from the seeds of the carob tree, Ceratonia siliqua), with CAGE-IL as a facilitator of transdermal permeation. Stability studies were carried out for six months, with analyses being performed at time intervals of 0 (24 h), 30, 60, 90, and 180 days. The samples were kept at 40 ± 2 °C, with 75 ± 5% relative humidity (RH). The parameters analyzed were morphological characteristics, pH (5.8-6.0), and spreadability. The samples were shown to be stable during the timeframe studied, maintaining adequate physicochemical characteristics and meeting quality specifications for cutaneous applications. CAGE-IL, in addition to facilitating permeation of the active substance, also favored the formation of a stable emulsion encompassing nanosized particles (134.3 ± 2.6 nm) in a simple fashion and with only a few components.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":"1 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68270542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

PARA QUÊ SE LÊ NA EDUCAÇÃO EM QUÍMICA? UMA ANÁLISE DE PUBLICAÇÕES EM PERIÓDICOS DE EDUCAÇÃO EM CIÊNCIAS ENTRE 2010 E 2021 为什么要在化学教育中阅读?2010年至2021年在科学教育期刊上发表的出版物分析

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-05-08 DOI: 10.21577/0100-4042.20170971

E. Santos, Wilmo Ernesto Francisco Junior

{"title":"PARA QUÊ SE LÊ NA EDUCAÇÃO EM QUÍMICA? UMA ANÁLISE DE PUBLICAÇÕES EM PERIÓDICOS DE EDUCAÇÃO EM CIÊNCIAS ENTRE 2010 E 2021","authors":"E. Santos, Wilmo Ernesto Francisco Junior","doi":"10.21577/0100-4042.20170971","DOIUrl":"https://doi.org/10.21577/0100-4042.20170971","url":null,"abstract":"WHAT ARE THE PURPOSES FOR READING IN EDUCATION IN CHEMISTRY? ANALYSIS OF ARTICLES PUBLISHED IN JOURNALS OF RESEARCH IN SCIENCE EDUCATION BETWEEN 2010 AND 2021. This work investigated Brazilian academic production about reading in chemistry classes published in journals of research in science education. To this end, a literature review was conducted from sixteen journals between 2010 and 2021. Two main aspects were analyzed: indicators of production (papers per year and per journals, education level, geographic region and institutions of the study) and the purposes of the activities of reading. In terms of the indicators of production, the results pointed out a consistent interest on this issue in the last decade with papers published in diverse journals, regional predominance from the Southeast and concentration of publications in high school or university levels. Regarding the purposes of reading, three main categories were identified: reading for information, reading for the development of skills and reading for scientific communication. Besides, different genre of texts has been employed in reading practices. Among the challenges are the reduction of regional asymmetries, the addressing of studies for other levels of education, as well as the increasing of research and systematic practices of reading based on a critical point of view.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":"1 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68268904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DESENVOLVIMENTO DE METODOLOGIA PARA DETERMINAÇÃO DE CANABINOIDES EM PRODUTOS À BASE DE CANNABIS PARA FINS MEDICINAIS 医用大麻产品中大麻素测定方法的发展

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-05-08 DOI: 10.21577/0100-4042.20230001

A. Dantas, Matheus Levy Almeida Taveira de Souza, Patrícia Ferreira Alexandre De Lima, M. Lima, D. Santana, Ricardo Maranho, A. Colonese, S. Ochs, M. Monteiro

{"title":"DESENVOLVIMENTO DE METODOLOGIA PARA DETERMINAÇÃO DE CANABINOIDES EM PRODUTOS À BASE DE CANNABIS PARA FINS MEDICINAIS","authors":"A. Dantas, Matheus Levy Almeida Taveira de Souza, Patrícia Ferreira Alexandre De Lima, M. Lima, D. Santana, Ricardo Maranho, A. Colonese, S. Ochs, M. Monteiro","doi":"10.21577/0100-4042.20230001","DOIUrl":"https://doi.org/10.21577/0100-4042.20230001","url":null,"abstract":"DEVELOPMENT OF A METHODOLOGY FOR THE DETERMINATION OF CANNABINOIDS IN CANNABIS-BASED PRODUCTS FOR MEDICINAL PURPOSES. Medicinal products based on the Cannabis sativa plant are available in Brazil, among them, drug, cannabis products, individual import products, and those provided by patient associations. Despite this, there is no monograph for the evaluation of cannabinoids in Brazilian Pharmacopoeia (BP) or other compendia accepted. Therefore, this work aimed to develop a quick and easy method to quantify cannabinoids in authorized products for medicinal purposes. The method was developed by HPLC-UV, gradient elution composed of formic acid in acetonitrile and water, the flow rate of 0.6 mL min-1 and 220 nm detection. It was possible to resolve the peaks of cannabidiol (CBD), tetrahydrocannabinol (THC), cannabidiolic acid and cannabinol and to quantify CBD (105.35%; 104.07%) and THC (106.62%). The developed method was applied to two products and met the established requirements of precision, accuracy, linearity, and selectivity. This procedure has been tested on four cannabisbased products to attest to its effectiveness. Considering the importance of establishing minimum quality requirements for medicinal products and considering the available products in Brazil, it was found that it is important to evaluate the implementation of other products in the method developed for future validation and later inclusion in the BP.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":"1 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68268961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EVALUATION OF ANTIMICROBIAL SENSITIVITY TO TETRACYCLINE EXPOSED TO NON-THERMAL PLASMA 非热等离子体暴露四环素的抗菌敏感性评价

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-05-08 DOI: 10.21577/0100-4042.20230006

A. Cubas, A. Dutra, Thiago Alves, R. Bianchet, Adriano Rambo, N. Debacher

{"title":"EVALUATION OF ANTIMICROBIAL SENSITIVITY TO TETRACYCLINE EXPOSED TO NON-THERMAL PLASMA","authors":"A. Cubas, A. Dutra, Thiago Alves, R. Bianchet, Adriano Rambo, N. Debacher","doi":"10.21577/0100-4042.20230006","DOIUrl":"https://doi.org/10.21577/0100-4042.20230006","url":null,"abstract":"Tetracyclines comprise a large group of broad-spectrum antibiotics used in human and veterinary medicine. Its mechanism of action, via oral ingestion, is to inhibit bacterial protein synthesis, but a large amount (70%) is eliminated without being metabolized, which presents a risk for the arising of antibiotic-resistant species. In this study, the degradation of Tetracycline TC by non-thermal plasma NTP and the antimicrobial sensitivity of the treated solution are investigated. The degradation was followed by chromatographic analysis while the efficiency of NTP in inhibiting the action of TC on bacteria was evaluated by antimicrobial sensitivity test by disk diffusion method. The results showed a high rate of TC degradation, over 90%, in 10 min of NTP treatment for a 60 mL (107 mg L-1) sample and very slow increase up to 94% in 30 min. The antimicrobial sensitivity test of TC after degradation by NTP showed no antibiotic activity. Therefore, our findings are encouraging, since the removal efficiency is below the minimum threshold require, to prevent with high probability, outgrowth of antibiotic-resistant bacteria. In addition, the results confirm that the NTP treated solution is safe to the environment.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":"1 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68270512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

CARACTERIZAÇÃO DE RESÍDUOS SÓLIDOS INDUSTRIAIS POR ANÁLISE TÉRMICA: PERSPECTIVAS DE USO COMO MATERIAL FILTRANTE PARA ÁGUAS RESIDUÁRIAS 工业固体废物热分析特性:作为废水过滤材料的应用前景

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-05-08 DOI: 10.21577/0100-4042.20230007

Roberta Beluco, E. Ionashiro, Núbia de Brito

{"title":"CARACTERIZAÇÃO DE RESÍDUOS SÓLIDOS INDUSTRIAIS POR ANÁLISE TÉRMICA: PERSPECTIVAS DE USO COMO MATERIAL FILTRANTE PARA ÁGUAS RESIDUÁRIAS","authors":"Roberta Beluco, E. Ionashiro, Núbia de Brito","doi":"10.21577/0100-4042.20230007","DOIUrl":"https://doi.org/10.21577/0100-4042.20230007","url":null,"abstract":"CHARACTERIZATION OF SOLID RESIDUES THROUGH THERMAL ANALYSIS: UTILIZATION PERSPECTIVE AS FILTER MATERIAL FOR WASTEWATER TREATMENT. Metallurgical waste and vermiculite are solid residues that have potential of utilization as filtering material. Nevertheless, they are commonly discarded. These materials have chemical sites like Si-O, Si-O-Si in vermiculite or have good ionic exchange properties like iron oxide compounds that can be used in adsorption processes. When these materials are combined with a synthetic blanket (OH, C=C, CO and C-H groups), it composes a filter layer with potential to be used in wastewater treatment. In this article, these materials were chemically treated and characterized by Thermogravimetry (TG), Differential Scanning Calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FTIR) and coupled TG-FTIR. The results suggest that organic compound contamination was not found after chemical treatment, which could have remained over the unity operations in the Metallurgical processes. The thermal and acid treatments influenced a major formation of iron oxide formation, but its oxidation degree (FeO, Fe2O3, or Fe2O3.FeO) were dependent on the sample granulometry. The Vermiculite shows an irreversible chemical modification after thermal treatment. The characterization of these residues shows its potential use as material in filter construction. Hence, it is fundamental to minimize the environmental impacts as well as to diminish the production costs in wastewater treatment.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":"1 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68270585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SEPARATION PERFORMANCE OF PEG-LINKED CALIX[4]ARENE AS STATIONARY PHASE FOR CAPILLARY GAS CHROMATOGRAPHY 毛细管气相色谱固定相环烷基杯芳烃的分离性能

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-05-08 DOI: 10.21577/0100-4042.20230013

Wei Zhang, Zhiqiang Cai, Wei Li, Qiuchen Huang, Ruonan Chen, Yiwen Li, Keyun Jin, Yi Zhao, T. Sun

引用次数: 0

A QUÍMICA NA LITERATURA DE PRIMO LEVI: ASPECTOS FILOSÓFICOS SOBRE EXPERIMENTAÇÃO, MATÉRIA E OFÍCIO QUÍMICO 普里莫·列维文学中的化学:实验、物质和化学工艺的哲学方面

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-05-08 DOI: 10.21577/0100-4042.20230008

R. Valero, Rafael Mori, L. Massi

{"title":"A QUÍMICA NA LITERATURA DE PRIMO LEVI: ASPECTOS FILOSÓFICOS SOBRE EXPERIMENTAÇÃO, MATÉRIA E OFÍCIO QUÍMICO","authors":"R. Valero, Rafael Mori, L. Massi","doi":"10.21577/0100-4042.20230008","DOIUrl":"https://doi.org/10.21577/0100-4042.20230008","url":null,"abstract":"CHEMISTRY IN PRIMO LEVI’S LITERATURE: PHILOSOPHICAL ASPECTS ON EXPERIMENTATION, MATTER AND THE PROFESSION OF CHEMISTRY. The Italian chemist Primo Levi (1919-1987) published a testimonial literature about the period he was captive in Auschwitz, later exploring other literary genres. In his work as a whole, the science-art relationship takes place both in terms of content (when chemistry and scientific knowledge are themes) and form (when the author appropriates the language and logic of science to communicate his experiences, especially those lived in the concentration camp). Three themes related to the chemical universe are present in Levi’s writings: experiments, man’s relationship with matter and chemistry as a work. In this article, we bring these topics closer to current discussions in the field of philosophy of chemistry. The philosophical discussion and Primo Levi’s literature converge on the understanding that experiments assumes a particular role in chemistry, that matter is a central category for this science and that the chemical profession raises ethical questions, such as those related to impacts of the incessant production of new substances.","PeriodicalId":49641,"journal":{"name":"Quimica Nova","volume":"1 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68270690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

SIMULATION OF THE DIFFUSION PROCESS OF NaCl AND KCl IN OLIVE PULP USING THE FINITE ELEMENT METHOD 用有限元法模拟橄榄浆中NaCl和KCl的扩散过程

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-05-08 DOI: 10.21577/0100-4042.20230005

M. Clemente, Heloisa Silva, Nathan Silva, Júlia Campos, E. D. De Sousa, H. Silva, A. Mantovani, Karina B. Angilelli, D. Borsato

引用次数: 0

TOXICITY OF ZINC OXIDE TO SCLERACTINIAN CORALS AND ZOOXANTHELLAE: A BRIEF REVIEW 氧化锌对硬核珊瑚和虫黄藻的毒性研究进展

IF 0.8 4区化学

Quimica Nova Pub Date : 2023-05-08 DOI: 10.21577/0100-4042.20230003

Lúcio Freitas Neto, B. Espósito

引用次数: 1

LABORATORY INVESTIGATION OF X-RAY PHOTOLYSIS OF METHANOL ICE AND ITS IMPLICATION ON ASTROPHYSICAL ENVIRONMENTS 甲醇冰x射线光解的实验室研究及其对天体物理环境的启示