South African Journal of Obstetrics and Gynaecology最新文献_第6页

Glutathione peroxidase in ovarian cancer patients in Indonesia 印度尼西亚癌症卵巢患者谷胱甘肽过氧化物酶

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-10-28 DOI: 10.7196/SAJOG.1393

E. Handayani, D. Edianto, M. Sahil, L. Tobing, M. R. Yaznil

{"title":"Glutathione peroxidase in ovarian cancer patients in Indonesia","authors":"E. Handayani, D. Edianto, M. Sahil, L. Tobing, M. R. Yaznil","doi":"10.7196/SAJOG.1393","DOIUrl":"https://doi.org/10.7196/SAJOG.1393","url":null,"abstract":"Background . Glutathione peroxidase (GPx) is one of the antioxidant enzymes that maintain the balance of reactive oxygen species. GPx has a notable role in the progression of cancer, including ovarian cancer. Synthesis of this enzyme may be down-regulated in cases of ovarian cancer. As far as we are aware, this has not been studied in an Indonesian population. Objective. To identify the difference in serum GPx levels between ovarian cancer patients and healthy controls. Methods . This was an observational analytical study with a case–control design. The study was conducted in the Department of Obstetrics and Gynaecology at the Haji Adam Malik Hospital in Medan, Indonesia. Serum GPx levels were measured in 20 ovarian cancer patients and 20 control subjects. Results . The types of ovarian cancer identified by histopathology in this study included serous adenocarcinoma ( n =10; 50%) and various non-serous adenocarcinomas (50%). The mean (SD) serum GPx level was significantly lower in the cancer group (295.235 (244.479) mU/mL) than in the control group (743.546 (131.949) mU/mL) ( p 0.226). Conclusion . Serum GPx levels were found to be significantly lower in patients with ovarian cancer than in healthy controls. Further studies are needed to determine an appropriate cut-off level for serum GPx in ovarian cancer in this population.","PeriodicalId":49579,"journal":{"name":"South African Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.7196/SAJOG.1393","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42234036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The feasibility and advantages of laparoscopic surgery for ectopic pregnancy at a secondary hospital in South Africa 南非二级医院腹腔镜手术治疗异位妊娠的可行性和优势

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-10-28 DOI: 10.7196/SAJOG.1445

D. Armatas, G. Theron, R. Aronis

{"title":"The feasibility and advantages of laparoscopic surgery for ectopic pregnancy at a secondary hospital in South Africa","authors":"D. Armatas, G. Theron, R. Aronis","doi":"10.7196/SAJOG.1445","DOIUrl":"https://doi.org/10.7196/SAJOG.1445","url":null,"abstract":"Background. Ectopic pregnancy (EP) is a gynaecological emergency with implications for maternal morbidity worldwide. Laparoscopic surgery is the preferred method of surgical management in most cases, as it has been shown to improve patient outcomes and overall care and to be cost effective and efficient. Objectives. To investigate the feasibility of laparoscopic surgery for EP management at a secondary hospital, based on incidence rates and comparing surgery-associated variables and outcomes with those in laparotomy. Methods. A retrospective study design was used. All patients who were treated surgically for EP at the Worcester Provincial Hospital were included. The required sample size was 81. Data were collected from patient files and theatre reports. Cases were assigned to one of two cohorts based on the method of surgical management. Results. A total of 84 cases were identified, of which 48 (57.1%) were managed laparoscopically and 36 (42.9%) with laparotomy. The average surgical time was 34.6 minutes and 44.9 minutes for a laparotomy and a laparoscopy, respectively. Patients who were treated laparoscopically required significantly less postoperative pain relief and had shorter hospital stays. Conclusion. This study shows not only that laparoscopy treatment is a feasible option for EP in a secondary-hospital setting in South Africa, but also that the intervention is associated with significantly better patient outcomes than laparotomy. The demonstrated benefits make laparoscopy the preferred treatment modality for EP when surgical intervention is required.","PeriodicalId":49579,"journal":{"name":"South African Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.7196/SAJOG.1445","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46059969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late termination of pregnancy for fetal anomalies: Experience at a tertiary-care hospital in South Africa 因胎儿异常而延迟终止妊娠：南非一家三级护理医院的经验

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-10-28 DOI: 10.7196/SAJOG.1402

Fauziasham Shahid, P. Soma-Pillay

{"title":"Late termination of pregnancy for fetal anomalies: Experience at a tertiary-care hospital in South Africa","authors":"Fauziasham Shahid, P. Soma-Pillay","doi":"10.7196/SAJOG.1402","DOIUrl":"https://doi.org/10.7196/SAJOG.1402","url":null,"abstract":"Background. Early diagnosis and appropriate management of congenital anomalies can help prevent neonatal morbidity and mortality. Termination of pregnancy for severe congenital anomalies is permitted under South African law. Objective . To determine factors causing delayed diagnosis of lethal congenital abnormalities requiring late termination of pregnancy at Steve Biko Academic Hospital in Pretoria, South Africa. Methods. Medical records of pregnant women who presented with lethal fetal anomalies over a period of 7.5 years were analysed. Patients’ demographic profile, the interval from referral to feticide, gestational age at first scan and diagnosis, type of anomaly and feticide methods were considered. The cohort was divided in two groups based on timing of termination (i.e. earlier than 28 weeks and later than 28 weeks’ gestation) for statistical comparison. Results. The majority of women ( n =45; 78.9%) were younger than 35 years and had no chronic medical conditions or risk factors ( n =40; 70%). Although 30 women (52.6%) had been booked for antenatal examination early in their pregnancy, only three (5.2%) had a first-trimester scan. Mean time to referral was not significantly different between the women whose pregnancies terminated earlier than 28 weeks and those with a termination after 28 weeks ( p =0.671). Conclusion. A basic ultrasound scan in the second trimester is recommended for all pregnant women. Task shifting can be a viable option to provide this facility at primary and secondary health centres. A national registry should be established to document all late terminations for fetal anomalies.","PeriodicalId":49579,"journal":{"name":"South African Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.7196/SAJOG.1402","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49647455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Procalcitonin: Blood tests are useful but must be interpreted with caution – inflammatory markers are no exception 降钙素原：血液测试是有用的，但必须谨慎解读——炎症标志物也不例外

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-08-27 DOI: 10.7196/sajog.1484

W. Edridge

引用次数: 0

Audit of routine tests in the antenatal period in women delivering at National District Hospital, Bloemfontein, South Africa, in 2016 2016年南非布隆方丹国家地区医院分娩妇女产前常规检查审计

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-08-27 DOI: 10.7196/sajog.1438

W. J. Steinberg, G. Joubert, A. Adu-Parko, M. Godloza, N. P. Lehasa, N. Manele, N. Moselakgomo, M. Motsoikha

{"title":"Audit of routine tests in the antenatal period in women delivering at National District Hospital, Bloemfontein, South Africa, in 2016","authors":"W. J. Steinberg, G. Joubert, A. Adu-Parko, M. Godloza, N. P. Lehasa, N. Manele, N. Moselakgomo, M. Motsoikha","doi":"10.7196/sajog.1438","DOIUrl":"https://doi.org/10.7196/sajog.1438","url":null,"abstract":"Background. Infectious diseases are transmissible from mother to unborn child. Appropriate treatment during antenatal care is crucial. Objective. To determine whether routine antenatal tests (syphilis, HIV, Rhesus factor) were performed in women delivering at National District Hospital (NDH), Bloemfontein, South Africa, and whether treatment was initiated for women testing positive for these infections. Methods. This descriptive retrospective study consisted of 2 425 women who delivered between January and December 2016. Antenatal care history was obtained from the delivery register. Results. Nearly all women were tested for syphilis (99.1%), HIV (99.9%) and Rhesus factor (99.9%). A third (33.3%) of the patients who tested positive for syphilis were untreated. Of the 27.0% of patients who tested HIV-positive, 99.7% were recorded to have been on treatment. Just over half (54.3%) of the patients who tested Rhesus-negative received prophylaxis. Conclusion. A record of routine antenatal testing of women delivering at NDH was found. The reaction to positive results could improve.","PeriodicalId":49579,"journal":{"name":"South African Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.7196/sajog.1438","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43356032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adverse pregnancy outcomes associated with maternal prenatal ingestion of traditional medicine 与母体产前摄入传统药物相关的不良妊娠结局

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-08-27 DOI: 10.7196/sajog.1423

N. Ngene, A. Siveregi

引用次数: 4

Successful pregnancy in a patient with Swyer syndrome, or pure 46,XY gonadal dysgenesis Swyer综合征或纯46,xy性腺发育不良患者的成功妊娠

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-08-27 DOI: 10.7196/sajog.1448

A. Chrysostomou, M. Tsuari

引用次数: 2

A case of immune thrombocytopenic purpura complicated by HELLP syndrome 免疫性血小板减少性紫癜并发HELLP综合征1例

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-08-27 DOI: 10.7196/sajog.1353

S. Prithipal

引用次数: 0

Contents 内容

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-08-27 DOI: 10.7196/sajog.1486

Gertrude Fani

引用次数: 0

Evaluation of the effect of 10% lidocaine spray on reducing the pain of intrauterine device insertion: A randomised controlled trial 10%利多卡因喷雾剂减轻宫内节育器插入疼痛的效果评价：一项随机对照试验

South African Journal of Obstetrics and Gynaecology Pub Date : 2019-08-27 DOI: 10.7196/sajog.1383

M. Hajiesmaello, E. Mohammadi, H. Farrokh-Eslamlou

{"title":"Evaluation of the effect of 10% lidocaine spray on reducing the pain of intrauterine device insertion: A randomised controlled trial","authors":"M. Hajiesmaello, E. Mohammadi, H. Farrokh-Eslamlou","doi":"10.7196/sajog.1383","DOIUrl":"https://doi.org/10.7196/sajog.1383","url":null,"abstract":"Background. The intrauterine device (IUD) is among the most efficient contraceptive methods. However, IUD insertion is accompanied by pain and discomfort. Objectives. To evaluate the analgesic effects of 10% lidocaine spray in reducing pain during IUD insertion. Method. In a randomised clinical trial, 80 volunteers attending two clinics for IUD insertion were selected for study, and randomly allocated to two groups. The intervention group received four puffs of 10% lidocaine spray on their cervix prior to IUD insertion. The routine procedure (without an analgesic) was followed in the control group. The intensity of perceived pain in both groups was measured using a visual analogue scale from 0 to 10. Results. The two groups had significant differences in pain intensity at all stages of the procedure ( p <0.001). The most painful stage of the procedure was tenaculum placement (mean (standard deviation) pain intensity 2.2 (1.34) in the intervention group; 4.25 (1.92) in the control group). Conclusion. Based on our findings, 10% lidocaine spray can be applied as a non-invasive, inexpensive, easy-to-use and accessible method to decrease IUD insertion pain.","PeriodicalId":49579,"journal":{"name":"South African Journal of Obstetrics and Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.7196/sajog.1383","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44685698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0