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Seminars in Radiation Oncology最新文献

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The seemingly contradictory roles of radiation as focal to systemic therapy in hematologic malignancies 在血液系统恶性肿瘤中，放射治疗与全身治疗似乎相互矛盾的作用。
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2025-01-01 DOI: 10.1016/j.semradonc.2024.12.001
Yolanda D. Tseng MD, MPhil , N. George Mikhaeel MD
{"title":"The seemingly contradictory roles of radiation as focal to systemic therapy in hematologic malignancies","authors":"Yolanda D. Tseng MD, MPhil , N. George Mikhaeel MD","doi":"10.1016/j.semradonc.2024.12.001","DOIUrl":"10.1016/j.semradonc.2024.12.001","url":null,"abstract":"","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"35 1","pages":"Pages 1-3"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rising to the Top: How Immune-Checkpoint Inhibitors are Changing the Landscape of Treatment for Classic Hodgkin Lymphoma 上升到顶峰：免疫检查点抑制剂如何改变经典霍奇金淋巴瘤的治疗前景。
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2025-01-01 DOI: 10.1016/j.semradonc.2024.11.002
Ryan C. Lynch , Michael Sargent Binkley
{"title":"Rising to the Top: How Immune-Checkpoint Inhibitors are Changing the Landscape of Treatment for Classic Hodgkin Lymphoma","authors":"Ryan C. Lynch ,&nbsp;Michael Sargent Binkley","doi":"10.1016/j.semradonc.2024.11.002","DOIUrl":"10.1016/j.semradonc.2024.11.002","url":null,"abstract":"<div><div>Immune checkpoint inhibitors have transformed the future management of classic Hodgkin lymphoma (CHL) in the frontline and salvage settings. Both nivolumab and pembrolizumab have high efficacy in CHL allowing for reduction of chemotherapy and possibly the use of radiotherapy based on short-term follow-up. In this review article, we highlight recent trials enrolling patients with relapse and refractory classic Hodgkin lymphoma receiving monotherapy with PD-1 inhibitors as well as PD-1 and chemotherapy regimens. We also highlight frontline trials utilizing PD-1 inhibitors with chemotherapy with or without radiotherapy. Collectively, the role for radiotherapy in the frontline or salvage setting will become more defined with long-term follow-up of completed studies and results generated from future studies.</div></div>","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"35 1","pages":"Pages 40-46"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modern Treatment Delivery of Radiotherapy for Lymphomas and Leukemias: Making Every Gy Count 淋巴瘤和白血病放射治疗的现代传递：使每一个Gy计数。
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2025-01-01 DOI: 10.1016/j.semradonc.2024.10.001
Chirayu G. Patel , Pierre Loap , Youlia M. Kirova
{"title":"Modern Treatment Delivery of Radiotherapy for Lymphomas and Leukemias: Making Every Gy Count","authors":"Chirayu G. Patel ,&nbsp;Pierre Loap ,&nbsp;Youlia M. Kirova","doi":"10.1016/j.semradonc.2024.10.001","DOIUrl":"10.1016/j.semradonc.2024.10.001","url":null,"abstract":"<div><div>Radiotherapy has a long history in the treatment of lymphoma and leukemia, in which late toxicity outcomes have motivated current goals to improve how radiotherapy is delivered. Contemporary advanced radiotherapy techniques, including intensity modulated radiation therapy (IMRT), proton therapy, deep inspiration breath hold (DIBH), aim to reduce the risk of cardiac morbidity and second cancers caused by radiotherapy while maintaining local control. We use treatment of mediastinal and gastric lymphomas to introduce how modern techniques are chosen for optimal dose delivery, followed by an anatomic site-specific discussion of testicular, bone, and central nervous system disease.</div></div>","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"35 1","pages":"Pages 4-10"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future of Multidisciplinary Team in the Context of Adaptive Therapy 适应性疗法背景下多学科团队的未来
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2024-09-11 DOI: 10.1016/j.semradonc.2024.08.006
H.A. McNair PhD , M.F. Milosevic MD , P.J. Parikh MD , U.A. van der Heide PhD
{"title":"Future of Multidisciplinary Team in the Context of Adaptive Therapy","authors":"H.A. McNair PhD ,&nbsp;M.F. Milosevic MD ,&nbsp;P.J. Parikh MD ,&nbsp;U.A. van der Heide PhD","doi":"10.1016/j.semradonc.2024.08.006","DOIUrl":"10.1016/j.semradonc.2024.08.006","url":null,"abstract":"<div><p>The implementation and early adoption of online adaptive radiotherapy (oART) has required the presence of clinicians, physicists and radiation therapists (RTT) at the treatment console. The impact on each of them is unique to their profession and must be considered for safe and efficient implementation. In the short term future, widespread adoption will depend on the development of innovative workflows, and rethinking of traditional roles and responsibilities may be required. For the future, technologies such as artificial intelligence promise to change the workflow significantly in terms of speed, automation and decision-making. However, overall communication within the team will persist in being one of the most important aspects.</p></div>","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"34 4","pages":"Pages 418-425"},"PeriodicalIF":2.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green Horizons in Oncology: A Blueprint for Environmentally Sustainable Radiation Therapy Facilities 肿瘤学的绿色前景：环境可持续放射治疗设施蓝图
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2024-09-11 DOI: 10.1016/j.semradonc.2024.07.004
Claire C Baniel , Rachel A. Sabol , Robert Nieto , Jessica Scholey , Alon Witztum , Robert Chuter , Erqi Pollom , Seema Gandhi , Kaiyi Wang , Kavita K. Mishra , Katie E. Lichter , Catherine Park
{"title":"Green Horizons in Oncology: A Blueprint for Environmentally Sustainable Radiation Therapy Facilities","authors":"Claire C Baniel ,&nbsp;Rachel A. Sabol ,&nbsp;Robert Nieto ,&nbsp;Jessica Scholey ,&nbsp;Alon Witztum ,&nbsp;Robert Chuter ,&nbsp;Erqi Pollom ,&nbsp;Seema Gandhi ,&nbsp;Kaiyi Wang ,&nbsp;Kavita K. Mishra ,&nbsp;Katie E. Lichter ,&nbsp;Catherine Park","doi":"10.1016/j.semradonc.2024.07.004","DOIUrl":"10.1016/j.semradonc.2024.07.004","url":null,"abstract":"","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"34 4","pages":"Pages 426-432"},"PeriodicalIF":2.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1053429624000559/pdfft?md5=d0c713ed3402efa2b50a81b555dd685c&pid=1-s2.0-S1053429624000559-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pursuing New Horizons With New Collaborators: This Is the Future of Radiation Oncology 与新合作者一起追求新视野：这就是放射肿瘤学的未来
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2024-09-11 DOI: 10.1016/j.semradonc.2024.08.002
David A. Jaffray , Robert P. Coppes , Helen McNair , Akila Viswanathan
{"title":"Pursuing New Horizons With New Collaborators: This Is the Future of Radiation Oncology","authors":"David A. Jaffray ,&nbsp;Robert P. Coppes ,&nbsp;Helen McNair ,&nbsp;Akila Viswanathan","doi":"10.1016/j.semradonc.2024.08.002","DOIUrl":"10.1016/j.semradonc.2024.08.002","url":null,"abstract":"","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"34 4","pages":"Pages 367-369"},"PeriodicalIF":2.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Future of Safety and Quality in Radiation Oncology 放射肿瘤学安全与质量的未来
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2024-09-11 DOI: 10.1016/j.semradonc.2024.07.008
Wesley Talcott , Elizabeth Covington , Jose Bazan , Jean L. Wright
{"title":"The Future of Safety and Quality in Radiation Oncology","authors":"Wesley Talcott ,&nbsp;Elizabeth Covington ,&nbsp;Jose Bazan ,&nbsp;Jean L. Wright","doi":"10.1016/j.semradonc.2024.07.008","DOIUrl":"10.1016/j.semradonc.2024.07.008","url":null,"abstract":"<div><p>The increasing complexity of radiation therapy treatment presents new potentials for error and suboptimal care. High-performing programs thus not only require adherence to, but also ongoing improvement of, key safety and quality practices. In this article, we review these practices including standardization, risk analysis, peer review, and maintenance of strong safety culture, while also describing recent innovations and promising future directions. We specifically highlight the growing role of artificial intelligence in radiation oncology, both as a tool to deliver safe, high-quality care and as a potential new source of safety challenges.</p></div>","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"34 4","pages":"Pages 433-440"},"PeriodicalIF":2.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ROCR: Modernizing Radiation Oncology Payment to Embrace Innovation and Better Care ROCR：实现放射肿瘤学支付现代化，拥抱创新和更好的护理
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2024-09-11 DOI: 10.1016/j.semradonc.2024.07.002
Catheryn M. Yashar , Anne Hubbard , Casey Chollet-Lipscomb
{"title":"ROCR: Modernizing Radiation Oncology Payment to Embrace Innovation and Better Care","authors":"Catheryn M. Yashar ,&nbsp;Anne Hubbard ,&nbsp;Casey Chollet-Lipscomb","doi":"10.1016/j.semradonc.2024.07.002","DOIUrl":"10.1016/j.semradonc.2024.07.002","url":null,"abstract":"<div><p>Data demonstrates that hypofractionation is increasingly utilized based on evidence-based guidelines. The outdated Medicare fee-for-service approach penalizes radiation oncology (RO) practices from adopting hypofractionation, even as many patients benefit. To address the flawed fee-for-service payment system, which rewards volume over value, ASTRO introduced the Radiation Oncology Case Rate (ROCR) Value-Based Payment Program. ROCR shifts payment for RO services from fee-for-service to payment per patient or per episode. To address disparities, ROCR provides an evidence-based approach through the Health Equity Achievement in Radiation Therapy (HEART) initiative, providing transportation assistance payment for the underserved. Additionally, ROCR allows practices sufficient capital to maintain existing equipment and invest in new technology. This increases patient access to technological advancements allowing for more efficient, targeted, and personalized care with improved patient outcomes at a lower overall cost.</p></div>","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"34 4","pages":"Pages 474-476"},"PeriodicalIF":2.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future of Team-based Basic and Translational Science in Radiation Oncology 放射肿瘤学团队基础与转化科学的未来
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2024-09-11 DOI: 10.1016/j.semradonc.2024.07.007
R.P. Coppes PhD , L.V. van Dijk PhD
{"title":"Future of Team-based Basic and Translational Science in Radiation Oncology","authors":"R.P. Coppes PhD ,&nbsp;L.V. van Dijk PhD","doi":"10.1016/j.semradonc.2024.07.007","DOIUrl":"10.1016/j.semradonc.2024.07.007","url":null,"abstract":"<div><p>To further optimize radiotherapy, a more personalized treatment towards individual patient's risk profiles, dissecting both patient-specific tumor and normal tissue response to multimodality treatments is needed. Novel developments in radiobiology, using in vitro patient-specific complex tissue resembling 3D models and multiomics approaches at a spatial single-cell level, may provide unprecedented insight into the radiation responses of tumors and normal tissue. Here, we describe the necessary team effort, including all disciplines in radiation oncology, to integrate such data into clinical prediction models and link the relatively \"big data\" from the clinical practice, allowing accurate patient stratification for personalized treatment approaches.</p></div>","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"34 4","pages":"Pages 370-378"},"PeriodicalIF":2.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1053429624000584/pdfft?md5=25386a67713f626e3129cd01445748d2&pid=1-s2.0-S1053429624000584-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prioritizing Patient-Centered Care in a World of Increasingly Advanced Technologies and Disconnected Care 在技术日益先进、医疗服务日益脱节的世界里，优先考虑以患者为中心的医疗服务
IF 2.6 3区 医学
Seminars in Radiation Oncology Pub Date : 2024-09-11 DOI: 10.1016/j.semradonc.2024.07.001
Sarah Marion , Lauren Ghazal , Toni Roth , Kelly Shanahan , Bridgette Thom , Fumiko Chino
{"title":"Prioritizing Patient-Centered Care in a World of Increasingly Advanced Technologies and Disconnected Care","authors":"Sarah Marion ,&nbsp;Lauren Ghazal ,&nbsp;Toni Roth ,&nbsp;Kelly Shanahan ,&nbsp;Bridgette Thom ,&nbsp;Fumiko Chino","doi":"10.1016/j.semradonc.2024.07.001","DOIUrl":"10.1016/j.semradonc.2024.07.001","url":null,"abstract":"<div><p>With more treatment options in oncology lead to better outcomes and more favorable side effect profiles, patients are living longer—with higher quality of life—than ever, with a growing survivor population. As the needs of patients and providers evolve, and technology advances, cancer care is subject to change. This review explores the myriad of changes in the current oncology landscape with a focus on the patient perspective and patient-centered care.</p></div>","PeriodicalId":49542,"journal":{"name":"Seminars in Radiation Oncology","volume":"34 4","pages":"Pages 452-462"},"PeriodicalIF":2.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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