低分割放疗在头颈部肿瘤的最终治疗中的应用

IF 2.6 3区医学 Q3 ONCOLOGY

Seminars in Radiation Oncology Pub Date : 2025-03-14 DOI:10.1016/j.semradonc.2025.01.002

Dominic H. Moon M.D. , Musaddiq J. Awan M.D.

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引用次数: 0

摘要

在许多癌症中，低分割放射治疗的使用有所增加，尽管由于对急性和晚期毒性的担忧，其在头颈部癌症中的使用仍然有限。最近的回顾性和前瞻性研究表明，在头颈部治疗的最终、术后和术前设置中，低分割的初步安全性和有效性。本文旨在全面回顾这种疾病部位的新分离方案的基本原理和数据。我们还提供实用的临床和剂量学的见解基于我们的机构经验，在头颈癌的低分割。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Hypofractionated Radiation Therapy in the Definitive Management of Head and Neck Cancer

The use of hypofractionated radiation therapy has increased among many cancers, although its use in head and neck cancers remains limited due to concerns regarding acute and late toxicities. Recent retrospective and prospective studies demonstrate the preliminary safety and efficacy of hypofractionation in the definitive, postoperative, and preoperative settings for head and neck treatment. This article seeks to comprehensively review the rationale and data for novel fractionation schemes in this disease site. We also provide practical clinical and dosimetric insights based on our institutional experiences with hypofractionation in head and neck cancers.

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来源期刊

Seminars in Radiation Oncology 医学-核医学

CiteScore

5.80

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Each issue of Seminars in Radiation Oncology is compiled by a guest editor to address a specific topic in the specialty, presenting definitive information on areas of rapid change and development. A significant number of articles report new scientific information. Topics covered include tumor biology, diagnosis, medical and surgical management of the patient, and new technologies.