Archives of current medical research (ACMR)最新文献

{"title":"Evaluation of patients admitted to the hematology outpatient clinic for spontaneous ecchymosis: Does it suggest bleeding diathesis?","authors":"Seda YILMAZ, Rafiye CİFTCİLER, Mikail DAĞ","doi":"10.47482/acmr.1277981","DOIUrl":"https://doi.org/10.47482/acmr.1277981","url":null,"abstract":"Background: Spontaneous ecchymosis is a common reason for referral to the hematology outpatient clinic. It is important to determine whether the underlying bleeding is benign or a symptom of diathesis. Methods: The sample of this retrospective study consisted of 119 patients with normal platelet counts who presented to the adult hematology outpatient clinic with spontaneous ecchymosis between September 2021 and August 2022. The site of the ecchymosis, patients’ familial and bleeding histories, and the drugs they have been using were queried. Hemogram and coagulation parameters and peripheral smear findings of the patients were recorded, and their ISTH-SSC (International Society on Thrombosis and Haemostasis Scientific and Standardization Committee) Bleeding Assessment Tool scores were calculated. Results: The median age of the patients, of whom 113 (95%) were female and 6 (5%) were male, was 30 (18-85) years. The ecchymosis was in the extremities and the trunk in 110 (92.4%) and 9 (7.6%) patients, respectively. There was no significant difference between the patients with and without bleeding history in terms of the site of spontaneous ecchymosis, the hemogram parameters and peripheral smear findings. Similarly, the patients with and without factor deficiency have not differed significantly in terms of hemogram parameters and peripheral smear findings. Patients with any factor deficiency had significantly higher ISTH-SSC Bleeding Assessment Tool scores compared to the patients without factor deficiency. Conclusion: The findings of the study revealed that the site of ecchymosis and hemogram and coagulation parameters cannot be used as markers in the general sense, except for the ISTH-SSC Bleeding Assessment Tool scores, which predicted factor deficiency. Another finding of the study worth mentioning is the fact that number of patients with ecchymosis on the trunk among the patients presenting with the complaint of ecchymosis was significantly lower than that of patients with ecchymosis on the extremities.","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135580059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective investigation of the relationship between clinical and laboratory parameters and allergy tests in children with allergic rhinitis","authors":"Ugur ALTAS, Eray TUNCE, Zeynep Meva ALTAŞ, Fatih ÇİÇEK, Mehmet Yaşar ÖZKARS","doi":"10.47482/acmr.1309737","DOIUrl":"https://doi.org/10.47482/acmr.1309737","url":null,"abstract":"Background: It was aimed to investigate the relationship between neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), eosinophil-lymphocyte ratio (ELR), serum total immunoglobulin E (IgE) values and allergy test positivity in patients with allergic rhinitis (AR).
 Methods: The study is a descriptive study with a retrospective design. Data on patients aged 0-18 years with a diagnosis of AR were investigated retrospectively. Age, gender, hemogram parameters (leukocyte, eosinophil, lymphocyte, thrombocyte), total IgE values, allergy history and allergy test positivity were evaluated. A p value of less than 0.05 was considered as a statistically significant result.
 Results: In the study, the data of 230 pediatric patients with AR were analyzed. The median age of the children was 13 years (10-18). Of the patients 57.4% (n=132) were male, 42.6% (n=98) were female. All laboratory values, except PLR, of the patients with positive allergy test were higher than the patients with negative allergy test. This elevation in WBC, neutrophil, absolute eosinophil, eosinophil percentage, total IgE and ELR values was statistically significant (p","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135476848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wet cupping therapy removes oxidative stress related miRNAs","authors":"Berivan UNAT, Fatma Hümryra YERLİKAYA, Hayriye BALTAOĞLU ALP, Duygu ERYAVUZ ONMAZ","doi":"10.47482/acmr.1285642","DOIUrl":"https://doi.org/10.47482/acmr.1285642","url":null,"abstract":"Background: Wet cupping therapy is commonly used in different conditions such as hypertension, diabetes, inflammatory and infectious diseases. The mechanism of action of wet cupping therapy is not yet clear, however several studies have demonstrated that it has a role in limiting oxidative stress. The aim of this study was to investigate the effect of wet cupping therapy on oxidative stress-related miRNAs miRNA-34a, miRNA-200a, miRNA-21 levels and oxidant-antioxidant status markers malondialdehyde (MDA) and glutathione (GSH) levels.
 Methods: 60 healthy volunteer women aged 20-75 years (n=30, 20-45 years; n=30, 45-75 years) who were applied wet cupping at Konya Necmettin Erbakan University Meram Medical Faculty Traditional and Complementary Medicine Center were included in this study. Plasma miRNA-34a, miRNA-200a and miRNA-21 levels were analyzed by using real-time quantitative PCR (RT-PCR) analysis. MDA and GSH levels were measured using the commercial ELISA kits. 
 Results: MDA levels [2003.10 (1810.17-7392.15) vs 1884.04 (1800.10-4488.05), p=0.027] of wet cupping blood samples higher than venous blood samples, while GSH levels [125.97 (90.65-219.43) vs 131.77 (88.77-246.42), p=0.037] were lower. miRNA-34a [(0.94±0.74) vs (0.53±0.28), p","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135476849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the turnaround time in a newly established biochemistry laboratory","authors":"Alpaslan ÖZTÜRK, Gülşah DEMİRCİ","doi":"10.47482/acmr.1333906","DOIUrl":"https://doi.org/10.47482/acmr.1333906","url":null,"abstract":"Background: The aim of our study was to compare the request-to-result times in the central biochemistry laboratory of Etlik City Hospital temporally and between clinics and to reveal the reasons for the changes in these times.
 
 Methods: The time of acceptance of the samples to the Central Biochemistry Laboratory of Etlik City Hospital and the time of confirmation of the results were noted and the difference between these two times was taken.
 
 Results: Delay rates were significantly different between the inpatients in October, November and December (P","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135580052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of SGLT2 inhibitors on cardio-electrophysiological balance index in diabetic patients with preserved ejection heart failure","authors":"Gökhan GÖKALP, Nail Burak ÖZBEYAZ","doi":"10.47482/acmr.1346676","DOIUrl":"https://doi.org/10.47482/acmr.1346676","url":null,"abstract":"Background: Type 2 diabetes mellitus (DM) increases the risk of heart failure with preserved ejection fraction (HFpEF). The use of sodium-glucose co-transporter-2 (SGLT-2) inhibitors, which have been shown to have cardioprotective effects in HFpEF, has increased in frequency. The index of cardio-electrophysiological balance (iCEB) is a marker that can be calculated on electrocardiography (ECG) and has been proven to be a good predictor of ventricular arrhythmia. This study aimed to investigate the effects of SGLT-2 inhibitors on iCEB and iCEBc in type 2 DM patients with HFpEF. Methods: We retrospectively analyzed the data of 76 patients with type 2 DM with HFpEF who were started on SGLT-2 inhibitors. We compared the ECG parameters obtained at baseline and six-month follow-up. Results: The mean age of the patients included in the study was 64.7±8.9 years. When ECG parameters before and after treatment were compared, iCEB (4.33±1.95 vs. 4.24±1.50, p= 0.006) and iCEBc (4.67±1.35 vs. 4.59±1.36, p<0.001) values were found to be decreased compared to before treatment. Conclusion: The iCEB and iCEBc values of the patients decreased significantly after SGLT-2 inhibitors. These results suggest that SGLT-2 inhibitors may reduce the risk of ventricular arrhythmia in patients with HFpEF.","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135580061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-based Comparative Analysis of Diabetic Hand Ulcers and Diabetic Foot Ulcers","authors":"Çağla AMUTKAN ÇİÇEK","doi":"10.47482/acmr.1339401","DOIUrl":"https://doi.org/10.47482/acmr.1339401","url":null,"abstract":"Background:The Social Insurance Institution of Turkey reported that in 2021, there were approximately 12 million patients with diabetes under universal health insurance. and the expenditure was incurred for the treatment of complications was TL 2.6 billion.Although previous studies have analyzed the cost of diabetic foot ulcers, no study from Turkey has yet compared the costs of diabetic hand ulcers and foot ulcers and analyzed the relationship between the cost and demographic characteristics of patients. 
 Methods:From January 2022 to June 2022, the data of 49 patients with diabetic hand ulcers and 44 patients with diabetic foot ulcers were analyzed retrospectively according to demographic datas and costs.Correlations were analyzed using cross tables, chi-square statistics, and partial correlation analysis, and groups were compared using t-test for independent groups and covariance analysis. 
 Results:The calculated average cost of patients who were followed up and treated for diabetic hand and foot ulcers was 257.01 USD and 462.54 USD, respectively. There was no statistically significant difference between the patients with diabetic hand and diabetic foot ulcers in terms of mean age, length of hospital stay, or HBA1C and CRP levels at admission. The mean cost of the diabetic hand was lower than that of the diabetic foot, and this difference was statistically significant.
 Conclusion:Although diabetic hand infections are less costly and cause fewer major amputations, it is a clinical condition that should be given at least as much attention as diabetic foot ulcer due to its atypical localized onset and the reproductive potential of different microorganisms.","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135580053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective analysis of traffic accidents related injuries in a tourism region","authors":"Mustafa ALPASLAN, Necmi BAYKAN","doi":"10.47482/acmr.1282407","DOIUrl":"https://doi.org/10.47482/acmr.1282407","url":null,"abstract":"Abstract Background: The number of applications to the emergency service after a traffic accident is quite high. In this study it is aimed to provide up to date data to the literature by making a detailed analysis of the patients who applied to the emergency department after an accident. Methods: This study was carried out by retrospectively scanning the patients who applied to the emergency department between 01.01.2022 and 31.12.2022 after a traffic accident in a secondary level hospital through the hospital electronic data. The patient’s admission date and time, age, gender, accident mechanisms, being a vehicle driver and ethanol positivity above the legal limit in the driver, as well as laboratory and imaging methods performed in the emergency department were examined. The injuries and outcomes seen in the patients were analyzed. Results: 1596 patients were evaluated within the scope of the study. The mean age of the patients was 32.93±19.26 years old and 66.7% were male. Among the accident mechanisms, 71.1% were found to be in vehicle traffic accidents. Head and neck tomography and extremity imaging were performed most frequently in the patients. Soft tissue trauma and extremity fractures were the most common cases. The discharge rate was 89.2%. It was concluded that hospitalized cases were most frequently made in neurosurgery, orthopedics and thoracic surgery clinics. Conclusions: The fact that vehicle drivers are drunk increases the risk of traffic accidents. The most common cause of fatal traffic accidents is cerebral hemorrhage. Increasing the safety measures that can be taken to prevent traffic accidents will reduce morbidity and mortality.","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135580060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the knowledge, attitudes and behaviors on active aging of people between 30-40 years: A multi-central cross-sectional study","authors":"Sevinç YILMAZ YELTEKİN, Süleyman GÖRPELİOĞLU","doi":"10.47482/acmr.1211570","DOIUrl":"https://doi.org/10.47482/acmr.1211570","url":null,"abstract":"Background: Aging is a physiological process that is seen in every human and causes a decrease in all functions.It is important to prepare the elderly population for the future as individuals who can take care of themselves, have low chronic diseases and have economic competence.It is an important and cost-effective method for healthy aging with primary prevention.The aim of this study is to analyze the knowledge, attitudes and behaviors of people aged 30-40, who are the elderly of the future, about active aging. Methods: This study was conducted face-to-face and over the calling with people aged 30-40 who applied to Family Health Center randomly selected across Turkey between March 2019 and January 2020 for any reason. A questionnaire including about socio-demographic information, health control, vaccinations, smoking and other addictions, nutrition, sports habits and hobbies questions prepared by the researchers was applied to the participants. Results:300 people were included in the study. When the medical precautions taken by the participants regarding their health were questioned;blood pressure of 68.0%; blood sugar of 69.3%; 65.0% had their blood fats measured; vision of 70.7%; 79.0% had teeth; 31.7% hear; It was observed that 11.0% of them had occult blood examination in the stool. Conclusions: The results of our study are individuals between the ages of 30-40; revealed that they do not plan for healthy aging. Preparing for a healthy aging period while still young is extremely important in terms of transforming the measures to be taken into a lifestyle.","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135476847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary epiploic appendagitis: A retrospective analysis of clinical and tomographic findings in 14 patients","authors":"Belma ÇEVİK, Benan KASAPOĞLU","doi":"10.47482/acmr.1340949","DOIUrl":"https://doi.org/10.47482/acmr.1340949","url":null,"abstract":"Background: The aim of this study is to describe the clinical features and imaging findings of 14 patients diagnosed with primary epiploic appendagitis on computed tomography (CT). Methods: Between January 2019 and August 2022, the hospital records of 14 patients were retrospectively reviewed. We recorded patients' age, gender, fever presence, blood leukocyte count (WBC), C-reactive Protein (CRP) level, localization of abdominal pain, the presence of nausea or vomiting, the involved part of the colon on CT, whether they received treatment or not, and whether they underwent surgery. Results: This study included 14 patients, 8 male and 6 female. Their ages ranged from 27 to 63 years. All patients presented with acute abdominal pain in most cases, with no elevation in body temperature or significant increase in inflammation markers. CT scan images showed a fat oval lesion corresponding to the inflamed Appendix epiploica, with a peripheral hyper-attenuated frame and a central \"dot\" in some cases referring to the thrombosed vessel. The patients were successfully treated with conservative methods. Conclusions: Epiploic appendagitis can mimic surgical diseases such as appendicitis and diverticulitis due to its non-specific clinical presentation. CT scan is essential in diagnosing this disease, which can be managed with more conservative treatment methods.","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135580058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of COVID-19 Pandemic on Emergency Department Admissions","authors":"Begüm ÖKTEM ÜZER, Secdegül COŞKUN YAŞ, Zeynep GÖKKUŞ, Fatma Mutlu KUKUL GÜVEN, Ahmet DEMİRCAN","doi":"10.47482/acmr.1266328","DOIUrl":"https://doi.org/10.47482/acmr.1266328","url":null,"abstract":"Background: This study has been conducted to evaluate the emergency department (ED) admissions during the pandemic period. &#x0D; Method: The study is a multicentre, retrospective study. ED admissions in two hospitals between April 1st, 2019 and May 31st, 2019 (pre-COVID-19 period); and between April 1st, 2020 and May 31st, 2020 (the period of COVID-19) have been compared. &#x0D; Result: Among 47888 ED admissions, 22854 (47.7%) females and 25034 (52.3%) males, with a mean age of 40.9±19.6 years have been included in the study. Of all patients, 30.1% (14440) were admitted to the EDs during the pandemic period in 2020. When the processes have been compared, it can be seen that while more laboratory examinations were requested from the EDs in the pre-pandemic period, more radiological examinations were requested during the pandemic period. Patients were consulted approximately 5 times more during the pandemic period than in the previous year. There has been a statistically significant difference between the periods in terms of consultation (p< 0.001). When the patients have been evaluated in terms of hospitalization, it can be seen that 5.1% of the patients were hospitalized in pre-pandemic period and 9.7% of the patients in the pandemic period (p","PeriodicalId":495147,"journal":{"name":"Archives of current medical research (ACMR)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135250532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}