{"title":"Association between executive and physical functions in people with Parkinson's disease.","authors":"Fatma Kübra Çekok, Turhan Kahraman, Arzu Genç, Gözde Duran, Berril Dönmez Çolakoğlu, Deniz Yerlikaya, Görsev Yener","doi":"10.1080/08990220.2023.2186393","DOIUrl":"10.1080/08990220.2023.2186393","url":null,"abstract":"<p><strong>Purpose: </strong>People with Parkinson's disease (PD) can develop cognitive and physical impairments. There is limited evidence on the association between executive function and physical function in people with PD.</p><p><strong>Objective: </strong>We aimed to investigate the association between the executive and physical functions in people with Parkinson's disease (PD) by comparing healthy controls.</p><p><strong>Method: </strong>Thirty-three patients diagnosed with PD and 33 healthy controls were included in the study. PD group was divided into two subgroups according to their scores on executive tests as high performers (PD-HPs; <i>n</i> = 17) and low performers (PD-LPs; <i>n</i> = 16). The severity of motor symptoms disease severity, executive function, global cognitive function, reaction time, hand function, functional capacity, physical activity, and balance confidence was assessed by the validated instruments.</p><p><strong>Results: </strong>The PD group had less physical function and executive function compared to healthy controls (<i>p</i> < 0.05). The PD-LPs group had less physical and cognitive function than the PD-HPs group (<i>p</i> < 0.05). The executive functions were significantly correlated with almost all variables in both people with PD and healthy people, and correlations were moderate to strong (<i>p</i> < 0.05). However, the correlation coefficients were relatively higher in people with PD compared to healthy controls.</p><p><strong>Conclusion: </strong>There was a significant association between executive and physical function in people with PD. Future studies should be conducted to determine whether the treatment of one of these dysfunctions affects the other.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"142-148"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9091337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Muscular endurance and its association with neck pain, disability, neck awareness, and kinesiophobia in patients with chronic neck pain.","authors":"Tuğba Dere, İpek Alemdaroğlu-Gürbüz","doi":"10.1080/08990220.2023.2186390","DOIUrl":"10.1080/08990220.2023.2186390","url":null,"abstract":"<p><strong>Background: </strong>Recent studies revealed the connection between the endurance of neck muscles and pain, neck awareness, and fear of movement in patients with chronic neck pain in literature.</p><p><strong>Objectives: </strong>To investigate the association between cervical, scapular, trunk, and upper extremity muscles' endurance and neck pain, disability, neck awareness, and kinesiophobia in patients with chronic neck pain.</p><p><strong>Design: </strong>Cross-sectional, observational study.</p><p><strong>Methods: </strong>Thirty-six patients with chronic neck pain (aged 18-65 years) were included in the study. Endurance tests were performed for 9 muscles/muscle groups in the cervical and scapular region, upper limb, and trunk. Pain severity, neck disability, neck awareness, and fear of movement were measured by Visual Analog Scale (VAS), Neck Disability Index (NDI), Fremantle Neck Awareness Questionnaire (FreNAQ), and Tampa Scale of Kinesiophobia (TSK), respectively.</p><p><strong>Results: </strong>Negative, weak-to-moderate relations were found between VAS (at rest and during activity) and the endurance of muscles evaluated in the cervical and scapular regions, upper extremity, and trunk as well as between NDI and endurance of the same muscles, similar to the relations between FreNAQ scores and the endurance of the cervical flexor, anterior trunk flexor, and upper extremity muscles (<i>p</i> < 0.05). No relation was found between the endurance of the muscles and TSK (<i>p</i> > 0.05).</p><p><strong>Conclusions: </strong>Since the decrease in upper extremity, scapular region, and trunk muscles' endurance may contribute to neck pain and disability, and decrease neck awareness in patients with chronic neck pain; the evaluation of muscular endurance of upper body and trunk should also be considered.</p><p><strong>Clinical trials: </strong>NCT05121467.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"134-141"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9137788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Mykins, Krista Marrero, Giuseppe Cataldo, Krithiga Aruljothi, Keerthi Krishnan, Joshua C Brumberg
{"title":"Barrels XXXV: barrels in-person.","authors":"Michael Mykins, Krista Marrero, Giuseppe Cataldo, Krithiga Aruljothi, Keerthi Krishnan, Joshua C Brumberg","doi":"10.1080/08990220.2023.2183833","DOIUrl":"10.1080/08990220.2023.2183833","url":null,"abstract":"<p><strong>Purpose of the study: </strong>After two years of virtual meetings, the Barrels Meeting resumed to an in-person format on 10 and 11 November 2022 in La Jolla California.</p><p><strong>Materials and methods: </strong>The meeting focused on the rodent sensorimotor system, with a focus on integrated information from the cellular to the systems level. A series of invited and selected oral presentations were delivered in addition to a poster session.</p><p><strong>Results: </strong>The latest results in the whisker-to-barrel pathway were discussed. Presentations included how the system encodes peripheral information, motor planning, and is disrupted in neurodevelopmental disorders.</p><p><strong>Conclusion: </strong>The 36th Annual Barrels Meeting brought together the research community to effectively discuss the latest advances in the field.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"123-133"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10873554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucas M Marques, Ana Castellani, Sara P Barbosa, Marta Imamura, Linamara R Battistella, Marcel Simis, Felipe Fregni
{"title":"Neuroplasticity changes in knee osteoarthritis (KOA) indexed by event-related desynchronization/synchronization during a motor inhibition task.","authors":"Lucas M Marques, Ana Castellani, Sara P Barbosa, Marta Imamura, Linamara R Battistella, Marcel Simis, Felipe Fregni","doi":"10.1080/08990220.2023.2188926","DOIUrl":"10.1080/08990220.2023.2188926","url":null,"abstract":"<p><strong>Purpose: </strong>Event-related desynchronisation (ERD) and event-related synchronisation (ERS) reflect pain perception and integration of the nociceptive sensory inputs. This may contribute to the understanding of how neurophysiological markers of Knee Osteoarthritis (KOA) patients can differ from control individuals, which would improve aspects such as prediction and prognosis. We performed a cross-sectional analysis of our cohort study (DEFINE cohort), KOA arm, with 71 patients, compared with 65 control participants. The study aimed to examine possible differences between ERD and ERS in control participants compared to Knee Osteoarthritis (KOA) patients when adjusting for important covariates.</p><p><strong>Materials and methods: </strong>We performed independent multivariate regression models considering as dependent variables the power value related to ERD and ERS for four different sensorimotor tasks (Motor Execution, Motor Imagery, Active Observation and Passive Observation) and four sensorimotor oscillations (Alpha, Beta, Low Beta, and High Beta), each model, controlled by age and sex.</p><p><strong>Results: </strong>We demonstrate that the differences between KOA and healthy subjects are frequency specific, as most differences are in the beta bandwidth range. Also, we observed that subjects in the KOA group had significantly higher ERD and ERS. This may be correlated to the amount of lack of brain organisation and a subsequent attempt at compensation induced by KOA.</p><p><strong>Conclusions: </strong>Our findings strengthen the notion that subjects with KOA have a higher degree of brain plasticity changes that are also likely correlated to the degree of compensation and behavioural dysfunction.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"149-158"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9155051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Postural stability and its relation to knee flexor/extensor strength ratio in women with mild to moderate unilateral knee osteoarthritis: a case-control study.","authors":"Sevtap Gunay Ucurum, Muge Kirmizi, Elif Umay Altas, Derya Ozer Kaya","doi":"10.1080/08990220.2023.2175809","DOIUrl":"10.1080/08990220.2023.2175809","url":null,"abstract":"<p><strong>Purpose/aim: </strong>Knee muscles strength is an important factor influencing postural stability in patients with knee osteoarthritis (KOA). However, there is no evidence regarding the relationship between the knee flexor/extensor strength ratio, which is suggested to be a good indicator of knee stability, and postural stability. We aimed to investigate postural stability and its relation to knee flexor and extensor strength and strength symmetry in women with KOA.</p><p><strong>Materials and methods: </strong>Thirty-five women with unilateral KOA and thirty-five asymptomatic women were assessed with the Prokin system to collect the following parameters during quiet standing with eyes-open and eyes-closed: ellipse area, perimeter, forward-backward standard deviation, mediolateral standard deviation, the average centre of pressure displacement on the x- and y-axises (COPX and COPY), and the limit of stability (LoS) score. Higher scores mean better balance for LoS and poorer balance for other parameters. Knee flexor and extensor strength were assessed bilaterally with the Lafayette hand-held dynamometer.</p><p><strong>Results: </strong>The COPX during standing with eyes-closed was higher in women with KOA than controls and the LoS score was lower (<i>p</i> < 0.05, Cohens'<i>d</i> = 0.72 and 0.65). Postural stability was correlated with knee muscles strength and the flexor/extensor strength ratios in both groups (r = between 0.395 and 0.456 for LoS, r = between -0.335 and -0.639 for the others, <i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Women with KOA had poorer postural stability in the mediolateral direction during standing with eyes-closed and a worse LoS score than controls. Postural stability was related to knee flexor and extensor strength and the flexor/extensor strength ratio in women.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"69-76"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10708169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effects of Kinesio taping on static and dynamic balance in children with down syndrome: a randomized controlled trial.","authors":"Pelin Atalan Efkere, Tülay Tarsuslu","doi":"10.1080/08990220.2023.2183829","DOIUrl":"10.1080/08990220.2023.2183829","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to determine the effects of Kinesio tape applied to the plantar soles on static and dynamic balance in children with Down syndrome (DS).</p><p><strong>Materials and methods: </strong>The study was carried out in children with DS. The participants were grouped as Kinesio Taping (KT) (n = 12, DS) and Sham Taping (ST) (n = 12, DS). The Functional Reach Test (FRT) was used to evaluate functional balance and the Fast-Timed Up and Go (FAST-TUG) test to evaluate functional balance and capacity. The Modified Clinical test of Sensory Interaction on Balance (MCTSIB) was used to evaluate static balance. For both groups, all the assessments were made three times: at baseline (T0), right after the taping application (T1), and 40-45 minutes later (T2).</p><p><strong>Results: </strong>Baseline FAST-TUG, FRT, and Eyes Open (EO) and Closed (EC) Sway velocity scores of the KT (medians- FAST-TUG:7.75 s, FRT:23.90 cm, EO: 0.70 deg/s, EC: 0.60 deg/s) and ST (medians-FAST-TUG:7.98 s, FRT:24 cm, EO: 0.85 deg/s, EC: 0.95 deg/s) groups were similar (<i>p</i> >0.05). Intragroup comparisons showed that FAST-TUG and FRT scores improved after the taping compared with T0 values in both KT (KT (FAST-TUG:7.75s-FRT:23.90cm)/KT1(FAST-TUG:7.55 s-FRT:28.25cm), KT(FAST-TUG:7.75s-FRT:23.90cm)/KT2(FAST-TUG:6.85s-FRT:27.50cm)) and ST groups (ST(FAST-TUG:7.98s-FRT:24cm)/ST1(FAST-TUG:7,95s-FRT:26.40cm), ST(FAST-TUG:7.98s-FRT:24cm)/ST2(FAST-TUG:7.26s-FRT:26.15cm)) (<i>p</i> < 0.05), while the sway velocity values were similar before and after the taping (<i>p</i> > 0.05).</p><p><strong>Conclusions: </strong>Taping on the plantar soles of children with DS may be affecting the immediate dynamic balance scores while it actually did not affect the static balance scores independent of the technique used. The interpretation of the results of this study should be made with caution. Further studies with long-term evaluations are needed.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"115-122"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10801031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hacı Ahmet Yarar, Selnur Narin, Mehmet Erduran, Iftikhar Gurbanov
{"title":"The test-retest reliability and concurrent validity of 360° turn test in patients with knee osteoarthritis.","authors":"Hacı Ahmet Yarar, Selnur Narin, Mehmet Erduran, Iftikhar Gurbanov","doi":"10.1080/08990220.2023.2178402","DOIUrl":"10.1080/08990220.2023.2178402","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study is to determine whether the 360° turn test is a reliable and valid evaluator that can be used to assess dynamic balance in patients with early (radiographic grades I and II) and advanced (radiographic grades III and IV) knee osteoarthritis.</p><p><strong>Materials and methods: </strong>This study is a methodological research. For the test time and step count of 360° turn test; test-retest reliability were determined by calculating the intraclass correlation coefficient and concurrent validity in patients with knee osteoarthritis was investigated by correlation with the timed up and go test time.</p><p><strong>Results: </strong>The final analysis was made on 117 participants. The intraclass correlation coefficient values for the test time and step count of 360° turn test in patients with early knee osteoarthritis are 0.931 and 0.902, respectively, while they are 0.923 and 0.943 in patients with advanced knee osteoarthritis. The Pearson correlation coefficients between the time and step count of 360° turn test and the test time of the timed up and go test in patients with early knee osteoarthritis, respectively; while they are 0.547 and 0.388, the correlation in patients with advanced knee osteoarthritis are 0.697 and 0.700, respectively (<i>p</i> < 0.01).</p><p><strong>Conclusions: </strong>The 360° turn test is a evaluator that has excellent test-retest reliability and moderate to strong concurrent validity in patients with both early and advanced knee osteoarthritis and can be used in the assessment of dynamic balance in this population.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"90-96"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10767563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Real-time vibrotactile pattern generation and identification using discrete event-driven feedback.","authors":"İsmail Erbaş, Burak Güçlü","doi":"10.1080/08990220.2023.2175811","DOIUrl":"10.1080/08990220.2023.2175811","url":null,"abstract":"<p><p>This study assesses human identification of vibrotactile patterns by using real-time discrete event-driven feedback. Previously acquired force and bend sensor data from a robotic hand were used to predict movement-type (stationary, flexion, contact, extension, release) and object-type (no object, hard object, soft object) states by using decision tree (DT) algorithms implemented in a field-programmable gate array (FPGA). Six able-bodied humans performed a 2- and 3-step sequential pattern recognition task in which state transitions were signaled as vibrotactile feedback. The stimuli were generated according to predicted classes represented by two frequencies (F1: 80 Hz, F2: 180 Hz) and two magnitudes (M1: low, M2: high) calibrated psychophysically for each participant; and they were applied by two actuators (Haptuators) placed on upper arms. A soft/hard object was mapped to F1/F2; and manipulating it with low/high force was assigned to M1/M2 in the left actuator. On the other hand, flexion/extension movement was mapped to F1/F2 in the right actuator, with movement in air as M1 and during object manipulation as M2. DT algorithm performed better for the object-type (97%) than the movement-type (88%) classification in real time. Participants could recognize feedback associated with 14 discrete-event sequences with low-to-medium accuracy. The performance was higher (76 ± 9% recall, 76 ± 17% precision, 78 ± 4% accuracy) for recognizing any one event in the sequences. The results show that FPGA implementation of classification for discrete event-driven vibrotactile feedback can be feasible in haptic devices with additional cues in the physical context.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"77-89"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10660588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blood flow restriction therapy with exercise are no better than exercise alone in improving athletic performance, muscle strength, and hypertrophy: a systematic review and meta-analysis.","authors":"Dimple Khurana, Neha Dutta, Shikha Malik, Shalini Sharma, M Minhaj, Raj Kumar Sharma, Saurabh Sharma","doi":"10.1080/08990220.2023.2181328","DOIUrl":"10.1080/08990220.2023.2181328","url":null,"abstract":"<p><strong>Background: </strong>The benefits of Blood Flow Restriction Therapy (BFRT) have gained attention in recent times.</p><p><strong>Objective: </strong>This review aimed to evaluate the immediate (up to 24 hours), intermediate (up to 6 weeks), and long term (6-10 weeks) effects of BFRT plus exercises (EX) compared to EX only on athletic performance (sprint and jump performance), muscle strength, and hypertrophy in athletes and physically active population.</p><p><strong>Methods: </strong>A literature search was conducted to select randomized controlled trials across four electronic databases from inception till April 2021. The search yielded twenty-seven studies in total.</p><p><strong>Results: </strong>Based on eligibility criteria, twenty-one studies were analyzed. No differences were found between both groups for immediate (standardized mean difference [SMD] -0.02, 95% confidence interval [CI] -0.31, 0.27) and long-term effects (SMD -0.30, 95%CI -0.90, 0.30) on sprint performance. For jump performance, no significant effect was observed immediately (SMD -0.02 (95% CI -1.06, 1.02) and long term (SMD -0.40 (95% CI -1.46, 0.67). Similarly, muscle torque at intermediate (SMD 0.90 (95% CI -1.01, 2.81) and long term (SMD -0.54 (95% CI -1.19, 0.12), muscle strength at intermediate (SMD 1.12 (95% CI 0.20, 2.04), and long term (SMD -0.07 (95% CI -0.56, 0.42) also showed non-significant effects. Muscle hypertrophy at intermediate (SMD 0.16 (95% CI -0.31, 0.63) and long term (SMD -0.20 (95% CI -0.90, 0.50) were not statistically significant.</p><p><strong>Conclusions: </strong>There was no significant difference observed in BFRT plus EX group compared to the EX-group on athletic performance, muscle strength, and muscle hypertrophy.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"97-114"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10769608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ioannis Nikolaidis, Maria-Valeria Karakasi, Artemios Artemiadis, Elli Nteli, Christos Bakirtzis, Marina-Kleopatra Boziki, Frederick W Foley, Nikolaos Grigoriadis
{"title":"Translation, cross-cultural adaptation, and validation of the Greek version of the Multiple Sclerosis Intimacy and Sexuality Questionnaire-19.","authors":"Ioannis Nikolaidis, Maria-Valeria Karakasi, Artemios Artemiadis, Elli Nteli, Christos Bakirtzis, Marina-Kleopatra Boziki, Frederick W Foley, Nikolaos Grigoriadis","doi":"10.1080/08990220.2022.2158801","DOIUrl":"10.1080/08990220.2022.2158801","url":null,"abstract":"<p><strong>Introduction: </strong>Multiple Sclerosis Intimacy and Sexuality Questionnaire-19 (MSISQ-19) explores optimally impact of MS on sexual activity/satisfaction/intimacy.</p><p><strong>Aim: </strong>The present study aims to provide the only validation of the Greek Version of MSISQ-19, and compare results to validation studies in other languages.</p><p><strong>Methods: </strong>The original/English version of the MSISQ-19 was translated into Greek according to standardized guidelines, while validity/reliability, correlations with other scales and sexual dysfunction prevalence were tested. Subjects were requested to complete all questionnaires and MSISQ-19, being re-tested three weeks later. Construct-validity of the Greek version of the MSISQ-19 was confirmed with principal-component-analysis. Bartlett's test assessed correlation-adequacy between items. Pearson's correlation explored internal-construct-validity between subscales and overall score, and external-construct-validity with disease-status variables, cognitive testing and patient-reported outcomes regarding fatigue, depression/anxiety, MS impact, and quality of life.</p><p><strong>Results: </strong>201 PwMS (130 female). Mean age was 39.3 ± 11.8 years with median disease-duration 11.7 ± 7.9 years. 79.1% RRMS, PPMS (10.4%) and SPMS (10.4%). Cronbach's alpha coefficient was 0.949. MSISQ-19 correlations between items were large. Significant associations of sexual dysfunction were identified with age (rho = 0.392, <i>p</i> < 0.01), years of education (rho=-0.199, <i>p</i> = 0.006), the Expanded Disability Status Scale (rho = 0.518, <i>p</i> < 0.01) and MS duration (rho = 0.354, <i>p</i> < 0.01). Correlations were disclosed with the Brief International Cognitive Assessment for MS (rho=-0.247, <i>p</i> < 0.05), Modified Fatigue Impact Scale (rho = 0.374, <i>p</i> < 0.05), Depression Anxiety Stress Scale (rho = 0.375, <i>p</i> < 0.05), Multiple Sclerosis Impact Scale (rho = 0.442, <i>p</i> < 0.05), and EuroQoL-five-dimensional instrument (rho = 0.375, <i>p</i> < 0.05). Internal consistency of the Greek version of the MSISQ-19 was confirmed with Cronbach's alpha. Test-retest reliability (31 PwMS) was excellent with intraclass-correlation-coefficients > 0.90.</p><p><strong>Conclusion: </strong>Besides Greek MSISQ-19 satisfactory validity/reliability/reproducibility and being first to include cognitive-testing, authors estimated sexual-dysfunction prevalence affecting half PwMS.HIGHLIGHTSThis study provides the only validation of the Greek Version of the MSISQ-19.The latter was found with satisfactory validity, reliability and reproducibility.50% of the Greek PwMS sample was found to be afflicted with sexual dysfunction.This is also the first validation study to examine associations with cognitive testing.Sexual function is still an underestimated functionality parameter upon examination.</p>","PeriodicalId":49498,"journal":{"name":"Somatosensory and Motor Research","volume":" ","pages":"1-10"},"PeriodicalIF":0.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10384788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}