Southeast Asian Journal of Tropical Medicine and Public Health最新文献

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The Relationship of Knowledge, Practices, and Culture on Low Coverage of Exclusive Breastfeeding 纯母乳喂养覆盖率低与知识、实践和文化的关系
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-06-10 DOI: 10.9734/ajmah/2023/v21i9850
Marniati, T. Alamsyah, Sufyan Anwar, Itza Mulyani, E. Putri
{"title":"The Relationship of Knowledge, Practices, and Culture on Low Coverage of Exclusive Breastfeeding","authors":"Marniati, T. Alamsyah, Sufyan Anwar, Itza Mulyani, E. Putri","doi":"10.9734/ajmah/2023/v21i9850","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i9850","url":null,"abstract":"Aims: The aims of this study was to analyze the influence of knowledge Practices and,Culture on the low coverage of exclusive breastfeeding. \u0000Introduction: Exclusive breastfeeding is breastfeeding as early as possible after delivery, given without schedule, and not given other food even if only water until the baby is six months old. Development Agency of the Indonesian Ministry of Health said Exclusive Breastfeeding in Aceh Province is 41.0%, the coverage of breastfeeding in Aceh Province is very low and has not reached the target set by the Indonesian Ministry of Health, which is 80%. West Aceh's exclusive breastfeeding coverage 44%, exclusive breastfeeding coverage is still far from the target. The Meutulang region for two consecutive years still has the same achievement rate of 13.4%. \u0000Study Design: Cross-Sectional Survey approach. \u0000Location and Duration of Study: Conducted in December 2022 (15 November-20 Desember) in Meutulang District, West Aceh, Aceh, Indonesia. \u0000Methods: The population of all mothers who have babies aged 6-12 months. Sampling by the total sampling method, where all polluters were sampled as many as 44 respondents were. Furthermore, the data were analyzed using univariate and bivariate and then tested with a Simple Linear Regression Model. \u0000Results: proved that there is an influence of knowledge, action, and culture on the low coverage of exclusive breastfeeding as evidenced by the correlation value (R) of 0.601 and the value of the coefficient of determination (R²) of 0.464, which means that the influence of the independent variable on the dependent variable is 46.4% where the correlation between the independent and dependent variables is in a strong category with value (Pvalue <0.05). \u0000Conclusion: There was an influence of knowledge with value (Pvalue 0.011<0.05), value action (Pvalue 0.028<0.05), and value culture (Pvalue 0.000<0.05) on the low coverage of exclusive breastfeeding. \u0000Suggestions: There needs to be more intense socialization and enlightenment by relevant officers in terms of mothers' understanding of exclusive breastfeeding so that mothers consider exclusive breastfeeding more important and can analyze the culture around them to give breast milk to their babies at least until the age of 6 months.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"65 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79741310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neterthon Syndrome Revealed by Recurrent Skin Infections: A Case Report 复发性皮肤感染引起的内特顿综合征1例报告
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-06-10 DOI: 10.9734/ajmah/2023/v21i8857
Ghizlane Jaabouti, N. Hafidi, C. Mahraoui
{"title":"Neterthon Syndrome Revealed by Recurrent Skin Infections: A Case Report","authors":"Ghizlane Jaabouti, N. Hafidi, C. Mahraoui","doi":"10.9734/ajmah/2023/v21i8857","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i8857","url":null,"abstract":"Netherton syndrome (NS) is a rare autosomal recessive disorder characterized by a triad of symptoms including a scaly skin condition known as circumflex linear ichthyosis, hair shaft abnormalities known as trichorrhexis invaginata, and an atopic terrain which predisposes patients to allergic reactions and asthma. \u0000The disorder is caused by mutations in the SPINK5 gene which encodes for a serine protease inhibitor called LEKTI. This leads to a disruption in the skin's natural barrier function and a hyperactive immune response, resulting in the characteristic symptoms of NS. \u0000Newborns with NS may have a poor prognosis, with possible life-threatening complications and high postnatal lethality. However, the symptoms can improve with age and growth, and management of the disorder is aimed at controlling the symptoms and preventing complications such as infections. Symptomatic treatment for cutaneous xerosis and management of infections are commonly used. Additionally, topical emollients and systemic immunoglobulin therapy may be used to help manage the condition. \u0000We present a clinical case that can help raise awareness about rare diseases such as Netherton syndrome and improve early diagnosis and management. It is important for healthcare providers to be familiar with the clinical and etiological characteristics of these conditions to ensure that patients receive appropriate care and treatment. \u0000The reported case is an infant of 3 months old, who presents from the age of 2 months a cutaneous xerosis under the care of a dermatologist, and managed by symptomatic treatment. Based on the clinical presentation and examination (The hair trichoscopy), the infant have Netherton syndrome with a superimposed bacterial infection leading to ichthyosis linearis circumflexa superinfected.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78076919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stevens-Johnson Syndrome Secondary to Herpetic Infection: A Case Report 疱疹感染继发史蒂文斯-约翰逊综合征1例报告
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-06-10 DOI: 10.9734/ajmah/2023/v21i8858
Ghizlane Jaabouti, Soumia Bencchakroun, C. Mahraoui, N. Hafidi
{"title":"Stevens-Johnson Syndrome Secondary to Herpetic Infection: A Case Report","authors":"Ghizlane Jaabouti, Soumia Bencchakroun, C. Mahraoui, N. Hafidi","doi":"10.9734/ajmah/2023/v21i8858","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i8858","url":null,"abstract":"Stevens-Johnson syndrome (SJS) is a rare but serious drug reaction characterized by extensive necrosis of the skin and mucous membranes. It is considered a medical emergency and requires immediate medical intervention, with a high mortality rate, especially during the acute phase. \u0000Symptoms of Stevens-Johnson syndrome include a rash, blisters, and lesions in the oral mucosa, throat, genitals, and eyes. Before the rash appears, symptoms such as fever, headache, muscle pain, and flu-like signs may occur. \u0000While the causes of Stevens-Johnson syndrome are not fully understood, it is often associated with an allergic reaction to medication. In children, it can also have an infectious origin. \u0000Survivors of Stevens-Johnson syndrome may experience long-term sequelae, including cutaneous, ophthalmological, genital, oral-dental, and psychological issues. Therefore, monitoring and early detection are crucial. \u0000The severity of this pathology makes the reported case particularly compelling. It highlights the importance of medical personnel having knowledge and mastery of this condition in order to improve management and prognosis. \u0000We report the case of an 8-year-old child who presented with a pseudogripal syndrome that rapidly progressed in 24 hours to an exanthem characterized by macules in pseudo-rings. The condition was complicated by a severe, diffuse enanthem and resulted in detachment with a positive Nikolsky sign. The clinical and biological evolution was favorable under symptomatic treatment, antiviral medication and intravenous immunoglobulin infusion.Top of Form","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"54 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84607538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceptions Regarding Occupational Health and Safety Attitudes of Hospital Pharmacists in Ambulatory Care in Pakistan 巴基斯坦医院药剂师在门诊护理中的职业健康和安全态度
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-06-10 DOI: 10.9734/ajmah/2023/v21i8849
Ayisha Hashmi, N. Nadeem, Khulda E. Zahra, M. Malik, A. Hussain
{"title":"Perceptions Regarding Occupational Health and Safety Attitudes of Hospital Pharmacists in Ambulatory Care in Pakistan","authors":"Ayisha Hashmi, N. Nadeem, Khulda E. Zahra, M. Malik, A. Hussain","doi":"10.9734/ajmah/2023/v21i8849","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i8849","url":null,"abstract":"Background: Standards for assessing and monitoring occupational health risks and safety measures for hospital pharmacists have been given prime importance in developed countries. However, occupational health and safety has often been neglected in developing countries. Lack of knowledge, poor training practices and insufficient resources are few of the reasons behind poor occupational health standards. \u0000Objective: The objective of the study was to assess perceptions regarding occupational health and safety attitudes of hospital pharmacists in ambulatory care in Pakistan. \u0000Methodology: A descriptive cross-sectional study design was used. The study respondents included hospital pharmacists working in Islamabad and Rawalpindi. Sample size was calculated to be 382 to achieve 95% confidence level with 5% margin of error. Convenient sampling technique was used to select respondents. A pre-validated tool Safety Attitudes Questionnaire-Ambulatory Version was used. Data was coded and analyzed using SPSS 21 after collection. Descriptive statistics comprising of frequency and percentages were calculated. Mann-Whitney and Kruskal-Wallis (p ≥ 0.05) tests were applied according to different demographic variables. \u0000Results: Significant difference (p<0.05) was observed in perceptions of occupational health and safety attitudes in ambulatory care among respondents of different genders, cities, education level, age groups, experience, setting and salary. Females had poor safety attitudes in ambulatory care as compared to male respondents. Respondents having experience between 1-5 years had poor safety attitude as compared to other respondents. Respondents working in private sector had poor occupational health and safety attitudes as compared to those working in public sector. \u0000Conclusion: The present study concluded that hospital pharmacists working in ambulatory care had satisfactory occupational health and safety attitudes. Respondents agreed that they had made errors due to workplace pressures and workload. Trainings should be conducted to improve the occupational health and safety attitudes of hospital pharmacists in ambulatory care.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"60 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80463170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low Viral Load Testing in HIV Patients on Antiretroviral Therapy: Mitigation Measures in Ghana 接受抗逆转录病毒治疗的艾滋病毒患者的低病毒载量检测:加纳的缓解措施
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-06-07 DOI: 10.9734/ajmah/2023/v21i8847
M. Asumah, A. Abubakari, M. Mutaka, D. Donkor, Raphael Abolasom Kumah
{"title":"Low Viral Load Testing in HIV Patients on Antiretroviral Therapy: Mitigation Measures in Ghana","authors":"M. Asumah, A. Abubakari, M. Mutaka, D. Donkor, Raphael Abolasom Kumah","doi":"10.9734/ajmah/2023/v21i8847","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i8847","url":null,"abstract":"The “Type of Article” of this paper is “Letter to the Editor”. This paper discuses about: “Low Viral Load Testing in HIV Patients on Antiretroviral Therapy: Mitigation Measures in Ghana”. No formal abstract is available. Readers are requested to read the full article.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"73 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83732754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing Diagnostic Accuracy of USG and CT Scan in Detecting Fatty Liver in Indonesian Patients: Implications for Screening and Management 比较USG和CT在印尼脂肪肝诊断中的准确性:对筛查和管理的意义
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-06-03 DOI: 10.9734/ajmah/2023/v21i8846
Anggraheny Soelistyaningtyas
{"title":"Comparing Diagnostic Accuracy of USG and CT Scan in Detecting Fatty Liver in Indonesian Patients: Implications for Screening and Management","authors":"Anggraheny Soelistyaningtyas","doi":"10.9734/ajmah/2023/v21i8846","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i8846","url":null,"abstract":"This study aimed to determine the accuracy of non-contrast USG and CT Scan in diagnosing fatty liver in Indonesian patients. Using a diagnostic test design with a cross-sectional approach, patients aged 40 years or older with laboratory examination results supporting NAFLD were selectively chosen from Dr. Soetomo Surabaya Hospital's Radiology Laboratory during February-March 2020. The study found that there is no significant difference in diagnostic accuracy between non-contrast USG and CT Scan in detecting NAFLD. Moreover, the majority of patients with NAFLD were women, and the highest prevalence was observed in the middle age range of 40-49 years. These findings suggest that clinicians should consider these demographic characteristics when screening and managing NAFLD in their patients. The choice of diagnostic test should be based on factors such as availability, cost, and patient preference.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"47 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88327765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Psychological Distress with Primary Dysmenorrhea among Adolescents Living in West Bengal, India 印度西孟加拉邦青少年心理困扰与原发性痛经的关系
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-05-24 DOI: 10.9734/ajmah/2023/v21i8842
Payel Pramanik, Purushottam Pramanik
{"title":"Association of Psychological Distress with Primary Dysmenorrhea among Adolescents Living in West Bengal, India","authors":"Payel Pramanik, Purushottam Pramanik","doi":"10.9734/ajmah/2023/v21i8842","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i8842","url":null,"abstract":"Background: Primary dysmenorrhea, a painful uterine cramp without any pelvic pathology that occur before or during menstruation among reproductive women. \u0000Objective: The objective of this study was to compare the psychological distress between adolescent female students with dysmenorrhea and without dysmenorrhea and also to examine relationship between psychological distress and dysmenorrhea. \u0000Methods: This is a cross sectional questionnaire based study conducted among 1646 adolescent female having age limit 14-19 years. Only unmarried adolescent females were included in the study however, females with gynecological, psychological or other medical problems were excluded from the study. It used validated and reliable questionnaire such as VAS for pain rating scale and DASS-21 for assessment of depression, anxiety, stress. Then, the descriptive data analysis and chi-square test were used to explore the relationship between psychological distress and dysmenorrhea. t-test was used to compare psychological distress between dysmenorrhea and non-dysmenorrhea. P<0.05 was considered as significant. \u0000Results: Mean age of the adolescent female was 15.91+ 1.27 years. Prevalence of dysmenorrhea was 88.94%. Among dysmenorrhea 22.40% was severe, 28.89% was under moderate and   48.71% was under mild dysmenorrhea. There was significant difference of psychological distress indices scores between dysmenorrhea and non-dysmenorrhea (p<0.001). Majority of dysmenorrheic females had severe to extreme severe levels of anxiety, depression and stress in contrast to non-dysmenorrheic females who have mild to moderate level. Significant association was noted between depression, anxiety, mental irritability and mood swing with primary dysmenorrhea (p<0.001). \u0000Conclusion: The present study suggested that dysmenorrhea is associated with psychological distress including anxiety, depression, mental irritation and mood swing. Psychological interventions and counselling are important for young women with primary dysmenorrhea to lessen the severity of menstrual pain.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"16 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85834374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Analysis of Radiation Dose Distribution and Organs at Risk in Breast Cancer Using Intensity Modulated Radiation Therapy Technique on A Linear Accelerator at RSUP Prof. Dr. I.G.N.G. Ngoerah 在RSUP线性加速器上使用调强放射治疗技术分析乳腺癌的辐射剂量分布和危险器官
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-05-23 DOI: 10.9734/ajmah/2023/v21i8840
Luqyana Latifa, N. Ratini, I. W. Sudarsana, Ida Bagus Made Suryatika, I. G. A. Ratnawati, A. Gunawan, R. Irhas
{"title":"Analysis of Radiation Dose Distribution and Organs at Risk in Breast Cancer Using Intensity Modulated Radiation Therapy Technique on A Linear Accelerator at RSUP Prof. Dr. I.G.N.G. Ngoerah","authors":"Luqyana Latifa, N. Ratini, I. W. Sudarsana, Ida Bagus Made Suryatika, I. G. A. Ratnawati, A. Gunawan, R. Irhas","doi":"10.9734/ajmah/2023/v21i8840","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i8840","url":null,"abstract":"The aim of the study was to analyze the radiation dose distribution in breast cancer cases using IMRT techniques on a LINAC equipment, specifically examining the Conformity Index (CI), Homogeneity Index (HI), and radiation dose distribution to the OAR, including lungs and heart on a 6 MV photon beam energy LINAC equipment at the Radiotherapy Sub-Installation of Prof. Dr. I.G.N.G Ngoerah Hospital. Analysis of the Conformity Index (CI), Homogeneity Index (HI) and radiation dose distribution to the OAR, namely the lungs and heart in cases of right and left breast cancer using statistical data on the Dose Volume Histogram (DHV) graphic obtained from patient calculations using the Treatment Planning System (TPS) Monaco. The CI value for the right and left breast cancer cases is 0.9819 and 0.9942 respectively with a nonparametric statistical test result of 0.141 that greater than 0.05 which means it is not significant. Meanwhile, the HI values for the right and left breast cancer cases are 0.1211 and 0.1410 respectively with the multivariate statistical test result of 0.159 that greater than 0.05 which means it is not significant. For the dose distribution values in the lungs close and far from the cancer, the average values of 32.24% and 440.03 cGy for right breast cancer and 33.04% and 500.55 cGy for left breast cancer were obtained, respectively, with a multivariate statistical test value for both of them of 0.115 that greater than 0.05 in the lungs close to the cancer and 0.124≥0.05 in the lungs far from the cancer, which means insignificant. As for the heart, a value of 3.13% was obtained for right breast cancer and 8.02% for left breast cancer with a nonparametric statistical test result of 0.000 that less than 0.05 which means significant. This can be caused by the position of the heart in cases of left breast cancer closer to the target or cancer than cases of left breast cancer.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"23 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82284292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Carbohydrate Type on Brain Composition and Senescence in Aging, Hyperinsulinemia-prone OBESE LA/Ntul//-cp Rats 碳水化合物类型对衰老、高胰岛素易感性肥胖LA/Ntul//-cp大鼠脑成分和衰老的影响
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-05-23 DOI: 10.9734/ajmah/2023/v21i8841
O. Tulp
{"title":"Effect of Carbohydrate Type on Brain Composition and Senescence in Aging, Hyperinsulinemia-prone OBESE LA/Ntul//-cp Rats","authors":"O. Tulp","doi":"10.9734/ajmah/2023/v21i8841","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i8841","url":null,"abstract":"To determine if phenotype and the carbohydrate type resulted in alterations in brain composition in the obese phenotype of the congenic LA/Ntul//-cp rat, groups (n= 8 rats/group) of male littermate lean and obese rats were fed standardized isocaloric diets containing 54% (w/w) cornstarch (ST diet) or 54% (w/w) sucrose (SUC diet) from 1 until 10.5 ± 0.5 months of age. The obese phenotype of his strain develops early onset chronic hyperinsulinemia without NIDDM associated with hypertrophic-hyperplastic obesity during early postweaning growth. Brain tissues were dissected, and representative aliquots subjected to total fat, protein, and DNA analysis. Body weights of obese >> lean and were greater when fed the SUC than the ST diet in both phenotypes. Brain mass of lean > obese, and diet was associated with modestly lower brain weights in rats fed the SUC than the ST diet. Brain total Protein and DNA content of lean rats were > obese rats and were modestly Lower in SUC than ST fed rats in both phenotypes, but the percent of lipid content was proportional to brain mass. Total body fat mass of obese was significantly greater than occurred in lean littermates and was only modestly greater in SUC than ST fed rats in both phenotypes. These results indicate that brain growth and cellular development is impaired in the aging, hyperinsulinemia-prone obese phenotype of this strain, were further impaired when fed SUC than ST diets, and the decreased brain parameters were likely associated with development of a chronic neuronal inflammatory syndrome common to excessive fat accretion and obesity, resulting in premature brain senescence.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"25 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82179065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Radiation Dose Distribution in Nasopharyngeal and Organ Cancer Cases at Risk with Linear Accelerator Radiotherapy 6 MV Photon Energy Using the IMRT Technique at Prof. Hospital. Dr. I. G. N. G. Ngoerah 6 MV光子能量线性加速器放射治疗危重鼻咽癌及脏器癌的放射剂量分布分析I. G. N. G. Ngoerah博士
IF 0.2 4区 医学
Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-05-18 DOI: 10.9734/ajmah/2023/v21i8838
Safitri Rahmaniyah, N. Ratini, I. W. Sudarsana, Ida Bagus Made Suryatika, K. N. Suarbawa, I. N. Artawan, A. Gunawan, R. Irhas
{"title":"Analysis of Radiation Dose Distribution in Nasopharyngeal and Organ Cancer Cases at Risk with Linear Accelerator Radiotherapy 6 MV Photon Energy Using the IMRT Technique at Prof. Hospital. Dr. I. G. N. G. Ngoerah","authors":"Safitri Rahmaniyah, N. Ratini, I. W. Sudarsana, Ida Bagus Made Suryatika, K. N. Suarbawa, I. N. Artawan, A. Gunawan, R. Irhas","doi":"10.9734/ajmah/2023/v21i8838","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i8838","url":null,"abstract":"This study aims to determine the distribution of radiation doses on PTV and OAR radioteraphy planning in RSUP. Prof. Dr. I.G.N.G Ngoerah, Bali, Indonesia does no exceed a predetermined limit. The research metode used is the value of Homogenity Index (H), Conformity Index (CI), and the maximum value of radiation ose to the Organ At Risk (OAR), amely the right eye lens, left eye lens, brainstem, optic chiasma, and spinal cord. These data are compared with the provisions of ICRU report 83 and the maximum dose reference value for OAR. Using data from 30 nasopharyngeal cancer patients with a total radiation dose of 7000 cGy. Obtained a value for HI of 0.1214 with a t-test result of 0.459> 0.05 which means it is not significant. While the value for CI is 0.9850 with nonparametric statistical test results of 0.285> 0.05 which means it is not significant. The maximum dose value for the right eye lens is 772.7 cGy with a t-test result of 0.779> 0.05 which means it is not significant. For the maximum value of the dose in the lens of the left eye of 771.0 cGy with a t test result of 0.791> 0.05 which means it is not significant. For the maximum value of the dose in the brain stem of 5178.1 cGy with nonparametric test results of 0.686> 0.05 which means not significant. The maximum dose value at the optic chiasma is 4,837.2 cGy with a nonparametric test result of 0.225>0.05 which means it is not significant. For the maximum value of the dose in the spinal cord of 4,663.3 cGy with a t test result of 0.958> 0.05 which means it is not significant.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"38 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78549321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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