在RSUP线性加速器上使用调强放射治疗技术分析乳腺癌的辐射剂量分布和危险器官

IF 0.1 4区医学 Q4 INFECTIOUS DISEASES

Southeast Asian Journal of Tropical Medicine and Public Health Pub Date : 2023-05-23 DOI:10.9734/ajmah/2023/v21i8840

Luqyana Latifa, N. Ratini, I. W. Sudarsana, Ida Bagus Made Suryatika, I. G. A. Ratnawati, A. Gunawan, R. Irhas

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引用次数: 0

摘要

本研究的目的是分析在LINAC设备上使用IMRT技术的乳腺癌病例的辐射剂量分布，特别是检查合格指数(CI)、均匀指数(HI)和辐射剂量分布到OAR，包括肺和心脏，在6 MV光子束能量LINAC设备上，I.G.N.G Ngoerah教授医院放射治疗分站。利用摩纳哥治疗计划系统(TPS)计算得出的剂量体积直方图(DHV)统计数据，分析右乳腺癌和左乳腺癌患者肺和心脏的一致性指数(CI)、均匀性指数(HI)和辐射剂量分布。右侧乳腺癌和左侧乳腺癌的CI值分别为0.9819和0.9942，非参数统计检验结果为0.141，大于0.05，无统计学意义。同时，右侧乳腺癌和左侧乳腺癌的HI值分别为0.1211和0.1410，多变量统计检验结果为0.159，大于0.05，无统计学意义。近肺和远肺的剂量分布值，右侧乳腺癌的平均值分别为32.24%和440.03 cGy，左侧乳腺癌的平均值分别为33.04%和500.55 cGy，近肺的剂量分布值均为0.115大于0.05，远肺的剂量分布值均为0.124≥0.05，不显著。对于心脏，右乳腺癌为3.13%，左乳腺癌为8.02%，非参数统计检验结果0.000 < 0.05，为显著性。这可能是由于左乳腺癌患者的心脏位置比左乳腺癌患者更接近目标或癌症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Analysis of Radiation Dose Distribution and Organs at Risk in Breast Cancer Using Intensity Modulated Radiation Therapy Technique on A Linear Accelerator at RSUP Prof. Dr. I.G.N.G. Ngoerah

The aim of the study was to analyze the radiation dose distribution in breast cancer cases using IMRT techniques on a LINAC equipment, specifically examining the Conformity Index (CI), Homogeneity Index (HI), and radiation dose distribution to the OAR, including lungs and heart on a 6 MV photon beam energy LINAC equipment at the Radiotherapy Sub-Installation of Prof. Dr. I.G.N.G Ngoerah Hospital. Analysis of the Conformity Index (CI), Homogeneity Index (HI) and radiation dose distribution to the OAR, namely the lungs and heart in cases of right and left breast cancer using statistical data on the Dose Volume Histogram (DHV) graphic obtained from patient calculations using the Treatment Planning System (TPS) Monaco. The CI value for the right and left breast cancer cases is 0.9819 and 0.9942 respectively with a nonparametric statistical test result of 0.141 that greater than 0.05 which means it is not significant. Meanwhile, the HI values for the right and left breast cancer cases are 0.1211 and 0.1410 respectively with the multivariate statistical test result of 0.159 that greater than 0.05 which means it is not significant. For the dose distribution values in the lungs close and far from the cancer, the average values of 32.24% and 440.03 cGy for right breast cancer and 33.04% and 500.55 cGy for left breast cancer were obtained, respectively, with a multivariate statistical test value for both of them of 0.115 that greater than 0.05 in the lungs close to the cancer and 0.124≥0.05 in the lungs far from the cancer, which means insignificant. As for the heart, a value of 3.13% was obtained for right breast cancer and 8.02% for left breast cancer with a nonparametric statistical test result of 0.000 that less than 0.05 which means significant. This can be caused by the position of the heart in cases of left breast cancer closer to the target or cancer than cases of left breast cancer.

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来源期刊

Southeast Asian Journal of Tropical Medicine and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-INFECTIOUS DISEASES

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

3-8 weeks

期刊介绍： The SEAMEO* Regional Tropical Medicine and Public Health Project was established in 1967 to help improve the health and standard of living of the peoples of Southeast Asia by pooling manpower resources of the participating SEAMEO member countries in a cooperative endeavor to develop and upgrade the research and training capabilities of the existing facilities in these countries. By promoting effective regional cooperation among the participating national centers, it is hoped to minimize waste in duplication of programs and activities. In 1992 the Project was renamed the SEAMEO Regional Tropical Medicine and Public Health Network.