Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland最新文献

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Do social media use and patient satisfaction scores correlate with online award recognition among hip and knee arthroplasty specialists? 社交媒体的使用和患者满意度评分与髋关节和膝关节置换术专家获得的在线奖项认可是否相关?
IF 2.5 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-04-26 DOI: 10.1016/j.surge.2024.04.006
Andrew R. Grant , Ruijia Niu , Abigail Smith , Elisabeth R. Grant , Eric L. Smith
{"title":"Do social media use and patient satisfaction scores correlate with online award recognition among hip and knee arthroplasty specialists?","authors":"Andrew R. Grant ,&nbsp;Ruijia Niu ,&nbsp;Abigail Smith ,&nbsp;Elisabeth R. Grant ,&nbsp;Eric L. Smith","doi":"10.1016/j.surge.2024.04.006","DOIUrl":"10.1016/j.surge.2024.04.006","url":null,"abstract":"<div><h3>Introduction</h3><p>The physician–patient interaction now begins before patients arrive in the office. Online ratings, social media profiles, and online award status are all components of physician online reputation which contributes to the patient's initial impressions. Therefore, it is important to understand the interplay of these factors and determine if there is a consistent trend indicating the value of this information.</p></div><div><h3>Methods</h3><p>We Identified all (N ​= ​160) registered American Association of Hip and Knee Surgeons (AAHKS) in New England using the <span>https://findadoctor.aahks.net/</span><svg><path></path></svg>tool for Massachusetts (MA), Connecticut (CT), Rhode Island (RI), Vermont (VT), New Hampshire (NH), and Maine (ME) on 6/26/2023. We collected surgeon age, fellowship graduation year, and practice type (i.e. Academic or Private). The average 5-star rating and number of ratings were collected from four websites. Any professional-use Facebook, Instagram, Twitter, LinkedIn, YouTube Channel, Personal Websites, or Institutional Websites were identified and a modified SMI Score was calculated. Finally, Castle Connolly Top Doctor, Local Magazine (e.g. Boston Magazine) Top Doctor, or the presence of having any award was noted for each surgeon.</p></div><div><h3>Results</h3><p>We identified several significant trends indicating that online awards were associated with higher online ratings. Social media presence, as determined by SMI Score, was also correlated with higher ratings overall and a higher likelihood of having an online award.</p></div><div><h3>Conclusion</h3><p>Given the observed trends and reported importance patients place on ratings and awards, surgeons may consider increasing online engagement via social media and encouraging patients to share their experience via online ratings.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 3","pages":"Pages 188-193"},"PeriodicalIF":2.5,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between psoas major muscle mass and CPET performance and long-term survival following major colorectal surgery: A retrospective cohort study 大肠手术后腰大肌质量与 CPET 表现和长期生存之间的关系:一项回顾性队列研究。
IF 2.5 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-04-22 DOI: 10.1016/j.surge.2024.04.005
Shahab Hajibandeh , Iain Gilham , Winnie Tam , Emma Kirby , Adetona Obaloluwa Babs-Osibodu , William Jones , George A. Rose , Damian M. Bailey , Christopher Morris , Rachel Hargest , Amy Clayton , Richard G. Davies
{"title":"Association between psoas major muscle mass and CPET performance and long-term survival following major colorectal surgery: A retrospective cohort study","authors":"Shahab Hajibandeh ,&nbsp;Iain Gilham ,&nbsp;Winnie Tam ,&nbsp;Emma Kirby ,&nbsp;Adetona Obaloluwa Babs-Osibodu ,&nbsp;William Jones ,&nbsp;George A. Rose ,&nbsp;Damian M. Bailey ,&nbsp;Christopher Morris ,&nbsp;Rachel Hargest ,&nbsp;Amy Clayton ,&nbsp;Richard G. Davies","doi":"10.1016/j.surge.2024.04.005","DOIUrl":"10.1016/j.surge.2024.04.005","url":null,"abstract":"<div><h3>Objectives</h3><p>To evaluate whether computed tomography (CT)-derived psoas major muscle measurements could predict preoperative cardiopulmonary exercise testing (CPET) performance and long-term mortality in patients undergoing major colorectal surgery and to compare predictive performance of psoas muscle measurements using 2D approach and 3D approach.</p></div><div><h3>Methods</h3><p>A retrospective cohort study compliant with STROCSS standards was conducted. Consecutive patients undergoing major colorectal surgery between January 2011 and January 2017 following CPET as part of their preoperative assessment were included. Regression analyses were modelled to investigate association between the CT-derived psoas major muscle mass variables [total psoas muscle area (TPMA), total psoas muscle volume (TPMV) and psoas muscle index (PMI)] and CPET performance and mortality (1-year and 5-year). Discriminative performances of the variables were evaluated using Receiver Operating Characteristic (ROC) curve analysis.</p></div><div><h3>Results</h3><p>A total of 457 eligible patients were included. The median TPMA and TPMV were 21 ​cm<sup>2</sup> (IQR: 15–27) and 274 ​cm<sup>3</sup> (IQR: 201–362), respectively. The median PMI measured via 2D and 3D approaches were 7 ​cm<sup>2</sup>/m<sup>2</sup> (IQR: 6–9) and 99 ​cm<sup>3</sup>/m<sup>2</sup> (IQR: 76–120), respectively. The risks of 1-year and 5-year mortality were 7.4% and 27.1%, respectively. Regression analyses showed TPMA, TPMV, and PMI can predict preoperative CPET performance and long-term mortality. However, ROC curve analyses showed no significant difference in predictive performance amongst TPMA, TPMV, and PMI.</p></div><div><h3>Conclusion</h3><p>Radiologically-measured psoas muscle mass variables may predict preoperative CPET performance and may be helpful with informing more objective selection of patients for preoperative CPET and prehabilitation.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 3","pages":"Pages 158-165"},"PeriodicalIF":2.5,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140773576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
‘Barbie Tox’ – A cosmetic trend with potential functional implications 芭比毒物"--一种具有潜在功能影响的美容趋势。
IF 2.5 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-04-17 DOI: 10.1016/j.surge.2024.04.001
Eimear M. Phoenix, Jake M. McDonnell, Joseph S. Butler, Colm Fuller, Colin M. Morrison, Roisin T. Dolan
{"title":"‘Barbie Tox’ – A cosmetic trend with potential functional implications","authors":"Eimear M. Phoenix,&nbsp;Jake M. McDonnell,&nbsp;Joseph S. Butler,&nbsp;Colm Fuller,&nbsp;Colin M. Morrison,&nbsp;Roisin T. Dolan","doi":"10.1016/j.surge.2024.04.001","DOIUrl":"10.1016/j.surge.2024.04.001","url":null,"abstract":"","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 3","pages":"Pages e157-e158"},"PeriodicalIF":2.5,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The public's perspective on the amount of time surgeons spend operating 公众对外科医生手术时间的看法。
IF 2.5 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-04-16 DOI: 10.1016/j.surge.2024.03.005
Kathryn Fu, James Walmsley, Mohamed Abdelrahman, David S.Y. Chan
{"title":"The public's perspective on the amount of time surgeons spend operating","authors":"Kathryn Fu,&nbsp;James Walmsley,&nbsp;Mohamed Abdelrahman,&nbsp;David S.Y. Chan","doi":"10.1016/j.surge.2024.03.005","DOIUrl":"10.1016/j.surge.2024.03.005","url":null,"abstract":"<div><h3>Background</h3><p>As waiting lists for elective surgery grow, there seems to be a disconnect between the public's expectations on the amount of time surgeons spend operating compared with reality. On average, a surgeon in the NHS spends one day a week performing elective surgery. We aimed to investigate the public's perception on the amount of time surgeons spend performing elective surgery and what they would desire.</p></div><div><h3>Methods</h3><p>Members of the public in the UK were approached randomly either on-line or in-person to complete an anonymised 6-question survey. The questionnaire included demographic details, surgical history, occupational experience in the healthcare sector, the number of days a week they believe and wish for surgeons to be performing elective surgery.</p></div><div><h3>Results</h3><p>252 members of the public responded to the survey (150 females, 102 males). 38.5% have experience working in the healthcare sector and 58.5% have had surgery in the past. 83.7% believe surgeons spend at least 3 days a week performing elective surgery [3–4 days (43.2%), 5–7 days (40.5%)]. 45.7% of respondents want their surgeon to operate between 5 and 7 days per week.</p></div><div><h3>Conclusion</h3><p>The public appears to overestimate the amount of time that surgeons spend performing elective surgery and have unrealistic expectations of how much they want their surgeons to operate.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 3","pages":"Pages 133-137"},"PeriodicalIF":2.5,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140781449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk stratification of best medical therapy for acute uncomplicated type B intramural hematoma 急性无并发症 B 型硬膜外血肿最佳药物治疗的风险分层。
IF 2.5 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-04-16 DOI: 10.1016/j.surge.2024.04.004
Kelvin Jeason Yang , Huey-Shiuan Kuo , Nai-Hsin Chi , Hsi-Yu Yu , Shoei-Shen Wang , I-Hui Wu
{"title":"Risk stratification of best medical therapy for acute uncomplicated type B intramural hematoma","authors":"Kelvin Jeason Yang ,&nbsp;Huey-Shiuan Kuo ,&nbsp;Nai-Hsin Chi ,&nbsp;Hsi-Yu Yu ,&nbsp;Shoei-Shen Wang ,&nbsp;I-Hui Wu","doi":"10.1016/j.surge.2024.04.004","DOIUrl":"10.1016/j.surge.2024.04.004","url":null,"abstract":"<div><h3>Objectives</h3><p>Best medical therapy (BMT) for acute uncomplicated type B intramural hematoma (TBIMH) is the current treatment guideline, but there is considerable controversy about subsequent clinical course and outcome, which may be associated with a significant failure rate. The purpose of this study was to identify potential risk factors for BMT failure and to develop a risk score to guide clinical decision making.</p></div><div><h3>Methods</h3><p>Patients with acute uncomplicated TBIMH between 2011 January and 2020 December were retrospectively studied. Logistic regression was applied to univariately assess potential risk predictors, and multivariable model results were then used to formulate a simplified predictive model for BMT failure.</p></div><div><h3>Results</h3><p>In a total of 61 patients, the overall rate of BMT failure was 57.4% (35/61), of which 48.6% (17/35) occurred within 28 days of onset. Logistic regression identified maximum descending aortic diameter (HR ​= ​1.99 CI ​= ​1.16–3.40, p ​= ​0.012), initial IMH thickness (HR ​= ​3.29, CI ​= ​1.28–8.46, p ​= ​0.013) and presence of focal contrast enhancement (HR ​= ​3.12, CI ​= ​1.49–6.54, p ​= ​0.003) as potential risk predictors of BMT failure. A risk score was calculated as follows: [Max DTA diameter (mm)∗0.6876 ​+ ​Max IMH thickness (mm)∗1.1918 ​+ ​PAU/ULP ∗1.1369]. Freedom from BMT failure at 1 year was 72% in patients with a risk score ​&lt; ​4.12, compared with only 35.1% in those with a risk score ​≧ ​4.12.</p></div><div><h3>Conclusions</h3><p>In a substantial proportion of patients with acute uncomplicated TBIMH, initial BMT failed. Based on the three initial computed tomographic imaging variables, this risk score could help stratify patients at high or low risk for BMT failure and provided additional information for early intervention.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 3","pages":"Pages e148-e154"},"PeriodicalIF":2.5,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140776799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phallus preservation and reconstruction: 5-year outcomes of national penile cancer centralisation in the Republic of Ireland 阴茎保留和重建:爱尔兰共和国全国阴茎癌集中治疗的 5 年结果。
IF 2.3 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-04-13 DOI: 10.1016/j.surge.2024.04.002
{"title":"Phallus preservation and reconstruction: 5-year outcomes of national penile cancer centralisation in the Republic of Ireland","authors":"","doi":"10.1016/j.surge.2024.04.002","DOIUrl":"10.1016/j.surge.2024.04.002","url":null,"abstract":"<div><h3>Introduction</h3><p><span><span>Penile cancer is a rare urological </span>malignancy with an age-standardised incidence of 0.8 per 100,000 person-years [1]. Given this low incidence it has been suggested that centralised care may improve patient outcomes in relation to </span>phallus sparing surgery and nodal assessment [2]. We aim to assess the outcomes after 5-years of national centralisation of penile cancer care.</p></div><div><h3>Methods</h3><p>A retrospective analysis of prospectively collected data was performed. All patients undergoing penile cancer surgery from January 2018 to December 2022 following centralisation of care were included. The primary outcome was proportion of phallus sparing procedures performed. Secondary outcomes were patient characteristics, histologic outcomes and procedures performed.</p></div><div><h3>Results</h3><p><span>124 patients underwent surgery in the study period. Mean age was 64.49 (±13.87). Overall, 82.3% of patients underwent phallus sparing surgery. This remained stable over the 5-year period from 2018 to 2022 ​at 92%, 85%, 76%, 79% and 78% respectively (p ​= ​0.534). 62.7% had reconstruction performed, including split-thickness skin graft neoglans formation, (57.8% [n ​= ​37]), preputial flap (32.8% [n ​= ​21]), glans resurfacing (4.7% [n ​= ​3]), shaft advancement flap (1.6% [n ​= ​1]), penile shaft skin graft (1.6% [n ​= ​1]), and partial </span>penectomy with urethral centralisation (1.6% [n ​= ​1]). Phallus preservation was not affected by positive nodal status (OR 0.75 [95% CI 0.249–2.266], p ​= ​0.564) or T-stage ≥1b (OR 0.51 [95% CI 0.153–1.711], p ​= ​0.276). There has been a significant reduction in Nx nodal status from 64% in 2017 to 15% in 2021 (p ​= ​0.009).</p></div><div><h3>Conclusion</h3><p>Centralisation of treatment for rare malignancies such as penile cancer may improve oncologic outcomes and rates of phallus preservation. This study has shown centralisation to has a high rate of phallus preservation. Further long-term analysis of outcomes in Ireland is required.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 5","pages":"Pages 292-295"},"PeriodicalIF":2.3,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140760958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative surgical outcomes of navigated vs non-navigated posterior spinal fusions in ankylosing spondylitis patients 强直性脊柱炎患者后路脊柱融合术中导航与非导航手术效果的比较。
IF 2.5 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-04-06 DOI: 10.1016/j.surge.2024.03.002
Harry Marland , Jake M. McDonnell , Lauren Hughes , Cronan Morrison , Kielan V. Wilson , Gráinne Cunniffe , Seamus Morris , Stacey Darwish , Joseph S. Butler
{"title":"Comparative surgical outcomes of navigated vs non-navigated posterior spinal fusions in ankylosing spondylitis patients","authors":"Harry Marland ,&nbsp;Jake M. McDonnell ,&nbsp;Lauren Hughes ,&nbsp;Cronan Morrison ,&nbsp;Kielan V. Wilson ,&nbsp;Gráinne Cunniffe ,&nbsp;Seamus Morris ,&nbsp;Stacey Darwish ,&nbsp;Joseph S. Butler","doi":"10.1016/j.surge.2024.03.002","DOIUrl":"10.1016/j.surge.2024.03.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Ankylosing Spondylitis (AS) patients with acute spinal fractures represent a challenge for practicing spine surgeons due to difficult operative anatomy and susceptibility to complications.</p></div><div><h3>Research question</h3><p>Does intraoperative CT-navigation improve outcomes in patients with ankylosing spondylitis undergoing surgery?</p></div><div><h3>Methods</h3><p>A retrospective review was carried out at our centre from 05/2016–06/2021 to identify AS patients presenting with a traumatic spinal fracture, managed surgically with posterior spinal fusion (PSF). Cohorts were categorised and compared for outcomes based on those who underwent PSF with intraoperative CT-navigation versus those surgically managed with traditional intraoperative fluoroscopy.</p></div><div><h3>Results</h3><p>37 AS patients were identified. 29/37 (78.4%) underwent PSF. Intraoperative navigation was used in 14 (48.3%) cases. Mean age of the entire cohort was 67.6 years. No difference existed between the navigated and non-navigated groups for mean levels fused (5.35 vs 5.07; p ​= ​0.31), length of operation (217.9mins vs 175.3mins; p ​= ​0.07), overall length-of-stay (12 days vs 21.9 days; p ​= ​0.16), patients requiring HDU (3/14 vs 5/15; p ​= ​0.09) or ICU (5/14 vs 9/15; p ​= ​0.10), postoperative neurological improvement (1/14 vs 1/15; p ​= ​0.48) or deterioration (1/14 vs 0/15; p ​= ​0.15), intraoperative complications (2/14 vs 3/15; p ​= ​0.34), postoperative complications 4/14 vs 4/15; p ​= ​0.46), revision surgeries (3/14 vs 1/15; p ​= ​0.16) and 30-day mortality (0/14 vs 0/15).</p></div><div><h3>Conclusion</h3><p>This is the first study that compares surgical outcomes of navigated vs non-navigated PSFs for AS patients with an acute spinal fracture. Although limited by its retrospective design and sample size, this study highlights the non-inferiority of intraoperative navigation as a surgical aid in a challenging cohort.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 3","pages":"Pages 182-187"},"PeriodicalIF":2.5,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1479666X24000295/pdfft?md5=cb6d9874cbd633b38b73ba96a5bbce7d&pid=1-s2.0-S1479666X24000295-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140734954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating the inevitable convergence of artificial intelligence and surgical training programs 引领人工智能与外科培训计划的必然融合。
IF 2.5 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-04-05 DOI: 10.1016/j.surge.2024.03.004
Mina Sarofim
{"title":"Navigating the inevitable convergence of artificial intelligence and surgical training programs","authors":"Mina Sarofim","doi":"10.1016/j.surge.2024.03.004","DOIUrl":"10.1016/j.surge.2024.03.004","url":null,"abstract":"","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 3","pages":"Pages e155-e156"},"PeriodicalIF":2.5,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140776741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prolonged interval to surgery following neoadjuvant chemoradiotherapy in locally advanced rectal cancer: A meta-analysis of randomized controlled trials 局部晚期直肠癌新辅助化疗后延长手术时间间隔:随机对照试验荟萃分析。
IF 2.5 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-03-22 DOI: 10.1016/j.surge.2024.03.001
P.W. Owens, M. Saeed, N. McCawley, P. Loughlin, D.E. Kearney, J.P. Burke, D.A. McNamara, S.M. Sahebally
{"title":"Prolonged interval to surgery following neoadjuvant chemoradiotherapy in locally advanced rectal cancer: A meta-analysis of randomized controlled trials","authors":"P.W. Owens,&nbsp;M. Saeed,&nbsp;N. McCawley,&nbsp;P. Loughlin,&nbsp;D.E. Kearney,&nbsp;J.P. Burke,&nbsp;D.A. McNamara,&nbsp;S.M. Sahebally","doi":"10.1016/j.surge.2024.03.001","DOIUrl":"10.1016/j.surge.2024.03.001","url":null,"abstract":"<div><h3>Background</h3><p>Long-course neoadjuvant chemoradiotherapy (NCRT), followed by surgery after an interval of 6–8 weeks, represents standard of care for patients with locally advanced rectal cancer (LARC). Increasing this interval may improve rates of complete pathological response (pCR) and tumour downstaging. We performed a meta-analysis comparing standard (SI, within 8 weeks) versus longer (LI, after 8 weeks) interval from NCRT to surgery.</p></div><div><h3>Methods</h3><p>PubMed, Embase, and Cochrane databases were searched up to 31 August 2022. Randomized controlled trials (RCTs) comparing SI with LI after NCRT for LARC were included. The primary endpoint was pCR rate. Secondary endpoints included rates of R0 resection, circumferential resection margin positivity (+CRM), TME completeness, lymph node yield (LNY), operative duration, tumour downstaging (TD), sphincter preservation, mortality, postoperative complications, surgical site infection (SSI) and anastomotic leak (AL). Random effects models were used to calculate pooled effect size estimates.</p></div><div><h3>Results</h3><p>Four RCTs encompassing 867 patients were included. There were 539 males (62.1%). LI was associated with a higher pCR rate (OR 0.61, 95%CI ​= ​0.39–0.95, p ​= ​0.03), and more TD (OR 0.60, 95%CI ​= ​0.37–0.97, p ​= ​0.04) compared to SI. However, there was no difference in rates of R0 resection (p ​= ​0.87), +CRM (p ​= ​0.66), sphincter preservation (p ​= ​0.26), incomplete TME (p ​= ​0.49), LNY (p ​= ​0.55), SSI (p ​= ​0.33), AL (p ​= ​0.20), operative duration (p ​= ​0.07), mortality (p ​= ​0.89) or any surgical complication (p ​= ​0.91).</p></div><div><h3>Conclusions</h3><p>A LI to surgery after NCRT for LARC increases pCR and TD rates. Local recurrence or survival were not assessed due to unavailable data. We recommend deferring TME until after an interval of 8 weeks following completion of NCRT.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 3","pages":"Pages 166-173"},"PeriodicalIF":2.5,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140194936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
List of editors 编辑名单
IF 2.5 4区 医学
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland Pub Date : 2024-03-21 DOI: 10.1016/S1479-666X(24)00022-2
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