{"title":"An unusual origin of the first septal perforator artery from the left main coronary artery: A rare case.","authors":"Burak Bozkurt, Mukan Kağan Kuş, Talib Durak, Nurefşan Bilici, Hakkı Aydoğan","doi":"10.4274/tjtcs.2025.27646","DOIUrl":"10.4274/tjtcs.2025.27646","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":"150-151"},"PeriodicalIF":0.9,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biological alternatives to chemical pleurodesis: Evaluation of autologous blood, platelet-rich plasma and platelet-rich fibrin in an experimental rat model.","authors":"Burcu Ancın, Simge Garlı, Özlem Özmen","doi":"10.4274/tjtcs.2025.28700","DOIUrl":"10.4274/tjtcs.2025.28700","url":null,"abstract":"<p><strong>Background: </strong>Pleurodesis is a widely used technique in thoracic surgery aimed at preventing the recurrence of pleural effusion and pneumothorax. Although chemical sclerosing agents such as talc are effective, their use is often limited by significant adverse effects, prompting interest in safer and more biocompatible alternatives. This experimental study evaluates the pleurodesis-inducing potential of three autologous biological agents-autologous blood (AB), platelet-rich plasma (PRP), and injectable platelet-rich fibrin (i-PRF)-in a rat model.</p><p><strong>Methods: </strong>Twenty-eight adult Wistar albino rats were randomly divided into four groups: control (saline), AB, PRP, and i-PRF. Each agent was administered intrathoracically, and the animals were observed over a 21-day period. Subsequently, pleural and pulmonary tissues were examined histopathologically.</p><p><strong>Results: </strong>PRP induced the most pronounced pleurodesis response, with significant pleural thickening, extensive fibrous adhesions, and dense collagen deposition. i-PRF, though less potent than PRP, showed a biocompatible and structurally organized fibrotic effect, with moderate collagen formation and minimal inflammation. AB elicited a modest, inconsistent pleurodesis response, with limited fibrotic remodeling.</p><p><strong>Conclusion: </strong>These findings suggest that platelet-based products, particularly PRP, may serve as effective and physiologically compatible alternatives to conventional chemical agents in pleurodesis. Furthermore, i-PRF represents a promising candidate in scenarios where minimizing inflammation is critical. This study is the first to evaluate i-PRF in pleurodesis and supports its potential translational application. Further clinical studies are warranted to validate these findings in human subjects.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":"185-191"},"PeriodicalIF":0.9,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gorham-Stout disease presenting as chest wall defect: A case report and review of literature.","authors":"Athish Kannan Karur, Dinesh Kumar Sathanantham, Jayakumar Thanathu Krishnan Nair, Adinarayanan Kishore Nochur, Samuel Olaniyan","doi":"10.4274/tjtcs.2025.28323","DOIUrl":"10.4274/tjtcs.2025.28323","url":null,"abstract":"<p><p>Gorham-Stout disease (GSD), also known as vanishing bone syndrome, is an extremely rare, non-malignant condition marked by progressive osteolysis due to abnormal intraosseous lymphatic and vascular proliferation. Extensive chest wall involvement is particularly uncommon and can present without symptoms, complicating diagnosis and management. In this study, a review of similar cases in the literatures is tabulated with comparison of this case to other articles is presented. A 24-year-old male presented with an incidental finding of \"hollowness\" in his right chest wall following a muscle strain, but remained asymptomatic otherwise. Imaging revealed near-total disappearance of the right 4th to 6th ribs anterolaterally, and partial resorption of the 7<sup>th</sup> and 8<sup>th</sup> ribs laterally. MRI confirmed extensive osteolysis with prominent lymphatic and vascular malformations. Histopathologic evaluation showed degenerative bony trabeculae with fibrous tissue and lymphovascular proliferations, confirming GSD. The patient was managed conservatively-vitamin D and calcium supplementation. No progression of disease was detected at subsequent follow-ups. This case underscores the need for high clinical suspicion and comprehensive evaluation in unexplained rib osteolysis. While various medical (bisphosphonates, sirolimus, interferon-α2b) and surgical interventions have been employed, no standard therapy is established. In asymptomatic patients without life-threatening complications, conservative management may be appropriate. The treatment should be personalized based on disease course and complications. The unpredictable prognosis mandates long-term monitoring.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":"213-217"},"PeriodicalIF":0.9,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Özkan Saydam, Gizem Özçıbık Işık, Celal Buğra Sezen, Merve Özbek Doğançay, Ezgi Nilay Yağcı Kazanasmaz, Mustafa Vedat Doğru, Levent Cansever
{"title":"Survival impact of pN2a and pN2b nodal status in stage IIB-IIIB non-small cell lung cancer under the 9<sup>th</sup> TNM classification.","authors":"Özkan Saydam, Gizem Özçıbık Işık, Celal Buğra Sezen, Merve Özbek Doğançay, Ezgi Nilay Yağcı Kazanasmaz, Mustafa Vedat Doğru, Levent Cansever","doi":"10.4274/tjtcs.2026.2025-12-14","DOIUrl":"10.4274/tjtcs.2026.2025-12-14","url":null,"abstract":"<p><strong>Background: </strong>Surgical resection in non-small cell lung cancer (NSCLC) is a potentially curative option in selected patients. Current TNM staging systems emphasize the prognostic role of pathological N (pN) status, and in the 9<sup>th</sup> TNM system pN2 disease is subdivided into single- (pN2a) and multiple-station (pN2b) N2 involvement. This study aimed to evaluate the impact of nodal status and other prognostic factors on survival in patients with stage IIB-IIIB NSCLC reclassified according to the 8<sup>th</sup> and 9<sup>th</sup> TNM systems.</p><p><strong>Methods: </strong>A total of 824 patients aged ≥18 years who underwent lung resection for NSCLC between 2007 and 2021 and were stage IIB, IIIA, or IIIB according to the 8<sup>th</sup> TNM system were included. Demographic, histopathologic, surgical, and survival data were retrospectively analyzed. All cases were restaged according to both the 8<sup>th</sup> and 9<sup>th</sup> TNM criteria, and the effects of lymph node status and pathological factors on survival were investigated.</p><p><strong>Results: </strong>The mean age was 59.7±8.58 years; 10.4% of patients were female. Squamous cell carcinoma (61.7%) and adenocarcinoma (32.5%) were the most common histologies. Lobectomy, pneumonectomy, and segmentectomy were performed in 52.3%, 46.8%, and 0.8% of patients, respectively. Age >70 years (p<0.001) and adenocarcinoma histology (p<0.001) were associated with worse survival, whereas gender and type of resection were not. pN2 disease had significantly worse survival than pN1 (p<0.001). In the 9<sup>th</sup> TNM system, pN2b had worse survival than pN1 and pN2a (p<0.001), while pN1 and pN2a did not differ significantly (p=0.088). Stage IIA/IIB patients had better survival than those with more advanced stages (p<0.001).</p><p><strong>Conclusion: </strong>pN status, particularly pN2 subgroups in the 9<sup>th</sup> TNM system, is a key determinant of survival in surgically treated stage IIB-IIIB NSCLC.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":"207-212"},"PeriodicalIF":0.9,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Denyan Mansuroğlu, Mehmet Balkanay, Oğuz Konukoğlu, Hakan Kilercik, Ali Doğan
{"title":"An unusual complication during implantation of left ventricular assist device: Ventricular septal defect and repair.","authors":"Denyan Mansuroğlu, Mehmet Balkanay, Oğuz Konukoğlu, Hakan Kilercik, Ali Doğan","doi":"10.4274/tjtcs.2025.27192","DOIUrl":"https://doi.org/10.4274/tjtcs.2025.27192","url":null,"abstract":"<p><p>In a patient undergoing left ventricular assist device implantation for ischemic cardiomyopathy, a ventricular septal defect developed during the apical coring procedure. The defect was successfully repaired using a synthetic patch through the sewing ring.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146229557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Life-threatening aortic pseudoaneurysm secondary to fish bone ingestion: A case report.","authors":"Salih Güler, Salih Toy, Fatih Ada","doi":"10.4274/tjtcs.2025.28623","DOIUrl":"https://doi.org/10.4274/tjtcs.2025.28623","url":null,"abstract":"<p><p>Foreign body ingestion is a common emergency presentation; however, aortic pseudoaneurysm and aortoesophageal fistula (AEF) secondary to fish bone ingestion are exceedingly rare. We report a case of thoracic aortic pseudoaneurysm and AEF caused by a fish bone. A 43-year-old male presented with chest pain one week after ingesting a fish bone. Clinical findings included fever, tachycardia, leukocytosis, elevated C-reactive protein, and anemia. Computed tomography angiography revealed a fish bone adjacent to a 27×17 mm thoracic aortic pseudoaneurysm. Due to hemodynamic instability, emergent zone 2 thoracic endovascular aortic repair (TEVAR) was performed, followed by endoscopic removal of the fish bone, nasogastric tube placement, and mediastinal drainage via mini-thoracotomy. Aortic pseudoaneurysm resulting from fish bone ingestion is life-threatening. TEVAR provides life-saving hemorrhage control in unstable patients, allowing subsequent definitive management.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146208216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Osman Fehmi Beyazal, Zeki Temiztürk, Mahmud Çelenkoğlu, Mehmed Yanartaş
{"title":"Pulmonary thromboendarterectomy and cavotomy of calcified superior vena cava.","authors":"Osman Fehmi Beyazal, Zeki Temiztürk, Mahmud Çelenkoğlu, Mehmed Yanartaş","doi":"10.4274/tjtcs.2025.28744","DOIUrl":"https://doi.org/10.4274/tjtcs.2025.28744","url":null,"abstract":"<p><p>Superior vena cava (SVC) calcification is very rare in adults, however it can lead to life-threatening complications such as pulmonary embolism. A 46-year-old female patient presented with complaints of shortness of breath. Computed tomography revealed widespread calcification in the SVC in addition to chronic thromboembolic pulmonary hypertension (CTEPH). In this case report, we present a patient who underwent pulmonary thromboendarterectomy due to CTEPH and endarterectomy and cavotomy due to calcification in the SVC.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rajat Nandi, Resham Singh, Utsav Rajvanshi, Kavita Vani
{"title":"Right aortic arch with left innominate artery compression syndrome: An unusual vascular aetiology of stridor in a neonate with complex CHD.","authors":"Rajat Nandi, Resham Singh, Utsav Rajvanshi, Kavita Vani","doi":"10.4274/tjtcs.2025.28631","DOIUrl":"https://doi.org/10.4274/tjtcs.2025.28631","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}