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Photodynamic therapy in the treatment of vulvar lichen sclerosus et atrophicus 光动力疗法治疗外阴硬化萎缩性地衣

Физиотерапевт Pub Date : 2023-10-11 DOI: 10.33920/med-14-2305-02

S. I. Surkichin, L. S. Kruglova, I. A. Apolikhina

{"title":"Photodynamic therapy in the treatment of vulvar lichen sclerosus et atrophicus","authors":"S. I. Surkichin, L. S. Kruglova, I. A. Apolikhina","doi":"10.33920/med-14-2305-02","DOIUrl":"https://doi.org/10.33920/med-14-2305-02","url":null,"abstract":"Lichen sclerosus (LS) is a chronic inflammatory disease that is 6–10 times more common in women than in men. LS affects between 1 in 1,000 and 1 in 300 people in the general population, but the exact prevalence is unknown since the disease is often asymptomatic. Objective: to evaluate the effectiveness of PDT in patients with LS in comparison with standard therapy methods. Material and methods: The study included 45 patients diagnosed with LS aged from 45 to 72 years (median age was 59 years). Depending on the therapy performed, the groups were divided into subgroups: Group 1A — patients with LS who were prescribed therapy with external glucocorticoids, Group 1B — patients with LS who were prescribed photodynamic therapy, Group 1C — patients with LS who were prescribed combined treatment: external glucocorticoids + PDT. Results: The study developed a special visual analogue scale to assess the objective condition of the vulva. VAS included the following parameters: pigmentation, skin pattern, turgor (skin fold straightening time), presence of cracks or erosions, and moisture. According to the data obtained, a complex treatment method using photodynamic therapy in patients with vulvar lichen sclerosus et atrophicus causes a higher effect than drug therapy and mono-PDT, which is confirmed by the dynamics of the total VAS index: 50.8 % compared with 28.2 % and 35.1 % in the comparison groups, respectively, therefore, it can be recommended for use in practical healthcare.","PeriodicalId":493919,"journal":{"name":"Физиотерапевт","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136253391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photodynamic therapy in the treatment of genitourinary menopausal syndrome 光动力疗法治疗泌尿生殖系统绝经综合征

Физиотерапевт Pub Date : 2023-08-12 DOI: 10.33920/med-14-2304-05

S. I. Surkichin, L. S. Kruglova, I. A. Apolikhina

引用次数: 0

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