Medicina Intensiva最新文献

{"title":"Pneumomediastinum radiologic signs: Naclerio's V and continuous diaphragm sign","authors":"Christopher Barrera-Hoffmann , Yadira Mariaca-Ortíz , Enrique Monares-Zepeda","doi":"10.1016/j.medin.2025.502171","DOIUrl":"10.1016/j.medin.2025.502171","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 8","pages":"Article 502171"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complicación del shock cardiogénico y uso de la ecografía","authors":"Julia Macías Clemente , Nora Palomo López , Gerardo Ferrigno Bonilla","doi":"10.1016/j.medin.2025.502150","DOIUrl":"10.1016/j.medin.2025.502150","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 8","pages":"Article 502150"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of respiratory physiotherapy in a patient with complete atelectasis of the left lung","authors":"Ramón Pérez-Gil , Gonzalo Ballesteros-Reviriego","doi":"10.1016/j.medin.2025.502204","DOIUrl":"10.1016/j.medin.2025.502204","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 8","pages":"Article 502204"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¿Mejora el surfactante precoz la evolución en el recién nacido pretérmino tardío? Estudio retrospectivo en una unidad de cuidados intensivos neonatal","authors":"Jorge Bartual Bardisa,&nbsp;Carolina Vizcaíno Díaz,&nbsp;María Jesús Ferrández Berenguer","doi":"10.1016/j.medin.2025.502161","DOIUrl":"10.1016/j.medin.2025.502161","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the early administration of surfactant, before 12<!--> <!-->hours of life, versus late, in late preterm neonates (born between 34<!--> <!-->+<!--> <!-->0 and 36<!--> <!-->+<!--> <!-->6 weeks of gestation), with moderate-severe respiratory distress.</div></div><div><h3>Design</h3><div>Retrospective, observational, analytical, case-control study, with late preterm infants admitted between 2012-2021. It is divided into 2 groups: surfactant administered ≤<!--> <!-->12<!--> <!-->hours of life and &gt;12<!--> <!-->h and evolution is compared using univariate analysis.</div></div><div><h3>Setting</h3><div>Neonatal Intensive Care Unit (NICU) level III of a Universitary Hospital.</div></div><div><h3>Patients or participants</h3><div>57 patients, 30 in the early group and 27 in the late group. Inclusion criteria: neonates from 34<!--> <!-->+<!--> <!-->0 to 36<!--> <!-->+<!--> <!-->6 weeks of gestation, with respiratory distress syndrome, in need of non-invasive ventilation and surfactant.</div></div><div><h3>Interventions</h3><div>None.</div></div><div><h3>Main variables of interest</h3><div>Sociodemographic, clinical and evolutionary: redosing, duration of respiratory support, oxygen and time to stop requiring it after surfactant. Also, complications and length of hospitalization.</div></div><div><h3>Results</h3><div>In the early group there was less need for redosing (3.3% vs 48.1%, <em>P</em>&lt;.001) and a decrease in duration, in days, of stay in the NICU (7 vs 10.5, <em>P</em> .002), invasive mechanical ventilation (2.4 vs 3.9, p0.034), total respiratory support (4.6 vs 6.6, <em>P</em>0.005) and oxygen therapy (0.4 vs 2.8, <em>P</em>&lt;.001). Also, lower incidence of pneumothorax (0% vs 33.3%, <em>P</em> .001). Furthermore, 12<!--> <!-->hours after administration, 83.4% maintained FiO₂ 0.21, compared to 44.4% in the late administration.</div></div><div><h3>Conclusions</h3><div>In our study, early administration in late preterm infants provides benefits in terms of respiratory assistance and complications. We suggest expanding studies to establish recommendations in this group of patients.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 8","pages":"Article 502161"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The endothelium or mitochondrial level therapy: new frontiers in sepsis?","authors":"Rashmi Datta ,&nbsp;Shalendra Singh","doi":"10.1016/j.medin.2024.502130","DOIUrl":"10.1016/j.medin.2024.502130","url":null,"abstract":"<div><div>The host and microbes play complex roles in balancing the pro- and anti-inflammatory pathways that cause sepsis. It is now increasingly recognized as a disorder of the mitochondrial system intrinsically or as a consequence of microcirculatory abnormalities leading to hypoperfusion/hypoxia (\"microcirculatory and mitochondrial distress syndrome”). It is expected that improvements in endothelium or mitochondrial level therapy will lower sepsis-related morbidity and mortality. This article aimed to clarify the mitochondrial and microcirculation abnormalities in patients with sepsis and the futuristic research agenda for the management of sepsis.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 8","pages":"Article 502130"},"PeriodicalIF":3.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous beta-blockers versus amiodarone on in-hospital mortality and safety profile in adult septic patients","authors":"Guoge Huang ,&nbsp;Haizhong Li ,&nbsp;Feier Song ,&nbsp;Chunmei Zhang ,&nbsp;Mengling Jian ,&nbsp;Chunyang Huang ,&nbsp;Yingqin Zhang ,&nbsp;Bei Hu ,&nbsp;Wenqiang Jiang","doi":"10.1016/j.medin.2025.502143","DOIUrl":"10.1016/j.medin.2025.502143","url":null,"abstract":"<div><h3>Objective</h3><div>In the present study, we aimed to compare in-hospital mortality and safety of intravenous beta-blockers and amiodarone in septic patients with new-onset atrial fibrillation (NOAF). The null hypothesis is that there is no significant difference in in-hospital mortality and safety of Beta-blocker (BBs) and amiodarone in treating NOAF in patients with sepsis.</div></div><div><h3>Design</h3><div>We conducted a retrospective analysis based on the MIMIC-IV database. Septic patients with NOAF were screened.</div></div><div><h3>Setting</h3><div>Patients admitted to adult mixed ICU for septic patients with NOAF.</div></div><div><h3>Patients</h3><div>A total of 34,789 patients were screened of whom 1394 patients were included for the analysis: 286 in the amiodarone group and 1108 in the BBs group.</div></div><div><h3>Interventions</h3><div>None.</div></div><div><h3>Main variables of interest</h3><div>Cox proportional hazard model was used to examine the in-hospital mortality, ventilator-free days and duration of atrial fibrillation in patients receiving either amiodarone or intravenous BBs. Propensity score matching was applied to determine any association.</div></div><div><h3>Results</h3><div>After Propensity Score (PS) matching, a total of 244 patients were included in both the BB and amiodarone groups. In this cohort, BBs was significantly associated with lower in-hospital mortality [adjusted hazard ratio (HR) of 0.70 (95% CI 0,54–0,91; P = 0.008)]. On the other hand, patients who received amiodarone had a shorter duration of atrial fibrillation (54.17 h vs 72.81 h; <em>P</em> = 0.003). There was no significant difference in ventilator-free days between the BB group and the amiodarone group.</div></div><div><h3>Conclusion</h3><div>In septic patients with NOAF, patients receiving BBs had lower in-hospital mortality than those who received amiodarone. On the other hand, amiodarone group had a shorter duration of atrial fibrillation. There was no significant difference in ventilator-free days between the BB group and the amiodarone group.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 7","pages":"Article 502143"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What should intensivists know about immune checkpoint inhibitors and their side effects?","authors":"Viktor Yordanov Zlatkov Aleksandrov,&nbsp;Fernando Martínez Sagasti,&nbsp;Juncal Pérez-Somarriba Moreno,&nbsp;Helena Huertas Mondéjar","doi":"10.1016/j.medin.2024.502135","DOIUrl":"10.1016/j.medin.2024.502135","url":null,"abstract":"<div><div>The pharmacological group of immune checkpoint-inhibitors (ICI) has revolutionized the field of oncology in the last ten years. The improvements in the survival of certain cancers thanks to these treatments comes at the cost of an increased morbidity and mortality due to certain immune related adverse events (irAE). This review will concentrate on the irAE that more frequently require intensive care unit (ICU) admission. The infectious burden of patients treated with ICI is also explored, shining light not only on the infections caused by the immunosuppression needed to manage the different irAE, but also on the specific infections arising from a unique immune dysregulation only seen in ICI treated patients.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 7","pages":"Article 502135"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seguridad y eficacia de betabloqueantes y amiodarona en el manejo de la fibrilación auricular de nueva aparición en el paciente crítico con sepsis","authors":"Alfonso Canabal Berlanga","doi":"10.1016/j.medin.2025.502159","DOIUrl":"10.1016/j.medin.2025.502159","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 7","pages":"Article 502159"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Niveles óptimos de hemoglobina en el paciente neurocrítico: ¿hemos llegado ya?","authors":"Manuel Quintana-Diaz ,&nbsp;Daniel Agustin Godoy","doi":"10.1016/j.medin.2025.502162","DOIUrl":"10.1016/j.medin.2025.502162","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 7","pages":"Article 502162"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respuesta a: «Vasopresina: ¿por qué no en la enfermedad traumática grave?»","authors":"Juan Carlos Ruíz-Rodríguez ,&nbsp;Ana Ochagavia ,&nbsp;Lluís Zapata ,&nbsp;Ricard Ferrer","doi":"10.1016/j.medin.2025.502220","DOIUrl":"10.1016/j.medin.2025.502220","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 7","pages":"Article 502220"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}