Critical Care and Resuscitation最新文献

{"title":"Current management of fluid balance in critically ill patients with acute kidney injury: A scoping review","authors":"Kyle C. White MBBS, MPH, FRACP, FCICM ,&nbsp;Ahmad Nasser MBChB, Dip. Child Health, M. Paed, FCICM ,&nbsp;Michelle L. Gatton PhD ,&nbsp;Kevin B. Laupland MD, PhD","doi":"10.1016/j.ccrj.2023.06.002","DOIUrl":"10.1016/j.ccrj.2023.06.002","url":null,"abstract":"<div><h3>Objective</h3><p>The overall objective of this scoping review is to assess the extent of the literature related to the fluid management of critically ill patients with acute kidney injury (AKI).</p></div><div><h3>Introduction</h3><p>AKI is common in critically ill patients where fluid therapy is a mainstay of treatment. An association between fluid balance (FB) and adverse patient-centred outcomes in critically ill patients with AKI regardless of severity has been demonstrated. The evidence for the prospective intervention of FB and its impact on outcomes is unknown.</p></div><div><h3>Inclusion criteria</h3><p>All studies investigating FB in patients with AKI admitted to an intensive care unit were included. Literature not related to FB in the critically ill patient with AKI population was excluded.</p></div><div><h3>Methods</h3><p>We searched MEDLINE, EMBASE, and CINAHL from January 1st, 2012, onwards. We included primary research studies, experimental and observational, recruiting adult participants admitted to an intensive care unit who had an AKI. We extracted data on study and patient characteristics, as well as FB, renal-based outcomes, and patient-centred outcomes. Two reviewers independently screened citations for eligible studies and performed data extraction.</p></div><div><h3>Results</h3><p>Of the 13,767 studies reviewed, 22 met the inclusion criteria. Two studies examined manipulation of fluid input, 18 studies assessed enhancing fluid removal, and two studies applied a restrictive fluid protocol. Sixteen studies examined patients receiving renal replacement therapy, five studies included non–renal replacement therapy patients, and one study included both. Current evidence is broad with varied approaches to managing fluid input and fluid removal. The studies did not demonstrate a consensus approach for any aspect of the fluid management of critically ill patients. There was a limited application of a restrictive fluid protocol with no conclusions possible.</p></div><div><h3>Conclusions</h3><p>The current body of evidence for the management of FB in critically ill patients with AKI is limited in nature. The current quality of evidence is unable to guide current clinical practice. The key outcome of this review is to highlight areas for future research.</p></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 3","pages":"Pages 126-135"},"PeriodicalIF":2.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48877915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving the management of medical emergency team calls due to suspected infections: A before–after study","authors":"Jeroen Ludikhuize MD, PhD ,&nbsp;David Marshall MD ,&nbsp;Misha Devchand MD, PhD ,&nbsp;Steven Walker MD, PhD ,&nbsp;Andrew Talman MD ,&nbsp;Carmel Taylor RN ,&nbsp;Tammie McIntyre RN ,&nbsp;Jason Trubiano MD, PhD ,&nbsp;Daryl Jones MD, PhD","doi":"10.1016/j.ccrj.2023.06.004","DOIUrl":"10.1016/j.ccrj.2023.06.004","url":null,"abstract":"<div><h3>Objective</h3><p>To introduce a management guideline for sepsis-related MET calls to increase lactate and blood culture acquisition, as well as prescription of appropriate antibiotics.</p></div><div><h3>Design</h3><p>Prospective before (Jun–Aug 2018) and after (Oct–Dec 2018) study was designed.</p></div><div><h3>Setting</h3><p>A public university linked hospital in Melbourne, Australia.</p></div><div><h3>Participants</h3><p>Adult patients with MET calls related to sepsis/infection were included.</p></div><div><h3>Main outcome measures</h3><p>The primary outcome measure was the proportion of MET calls during which both a blood culture and lactate level were ordered. Secondary outcomes included the frequency with which new antimicrobials were commenced by the MET, and the presence and class of administered antimicrobials.</p></div><div><h3>Results</h3><p>There were 985 and 955 MET calls in the baseline and after periods, respectively. Patient features, MET triggers, limitations of treatment and disposition after the MET call were similar in both groups. Compliance with the acquisition of lactates (p = 0.101), respectively. There was a slight reduction in compliance with lactate acquisition in the after period (97% vs 99%; p = 0.06). In contrast, there was a significant increase in acquisition of blood cultures in the after period (69% vs 78%; p = 0.035).</p></div><div><h3>Conclusions</h3><p>Introducing a sepsis management guideline and enhanced linkage with an AMS program increased blood culture acquisition and decreased broad spectrum antimicrobial use but didn't change in-hospital mortality.</p></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 3","pages":"Pages 136-139"},"PeriodicalIF":2.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46176287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential metrics for rapid response systems in Australia and New Zealand","authors":"Daryl Jones ,&nbsp;Judit Orosz ,&nbsp;Alex Psirides ,&nbsp;David Pilcher","doi":"10.1016/j.ccrj.2023.06.006","DOIUrl":"10.1016/j.ccrj.2023.06.006","url":null,"abstract":"","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 3","pages":"Pages 116-117"},"PeriodicalIF":2.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44535203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blend to Limit OxygEN in ECMO: A RanDomised ControllEd Registry (BLENDER) Trial: Study Protocol and Statistical Analysis Plan","authors":"Aidan Burrell PhD ,&nbsp;Sze Ng MBBS ,&nbsp;Kelly Ottosen MHealthSc ,&nbsp;Michael Bailey PhD ,&nbsp;Hergen Buscher MD ,&nbsp;John Fraser PhD ,&nbsp;Andrew Udy PhD ,&nbsp;David Gattas MMed(ClinEpi) ,&nbsp;Richard Totaro MBBS ,&nbsp;Rinaldo Bellomo PhD ,&nbsp;Paul Forrest MBChB ,&nbsp;Emma Martin BpharmSc ,&nbsp;Liadain Reid MPH ,&nbsp;Marc Ziegenfuss MBBS ,&nbsp;Glenn Eastwood PhD ,&nbsp;Alisa Higgins PhD ,&nbsp;Carol Hodgson PhD ,&nbsp;Edward Litton PhD ,&nbsp;Priya Nair PhD ,&nbsp;Neil Orford PhD ,&nbsp;David Pilcher MBBS","doi":"10.1016/j.ccrj.2023.06.001","DOIUrl":"https://doi.org/10.1016/j.ccrj.2023.06.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Critically ill patients supported with venoarterial extracorporeal membrane oxygenation (VA ECMO) are at risk of developing severe arterial hyperoxia, which has been associated with increased mortality. Lower saturation targets in this population may lead to deleterious episodes of severe hypoxia. This manuscript describes the protocol and statistical analysis plan for the Blend to Limit OxygEN in ECMO: A RanDomised ControllEd Registry (BLENDER) Trial.</p></div><div><h3>Design</h3><p>The BLENDER trial is a pragmatic, multicentre, registry-embedded, randomised clinical trial., registered at <span>ClinicalTrials.gov</span><svg><path></path></svg> (NCT03841084) and approved by The Alfred Hospital Ethics Committee project ID HREC/50486/Alfred-2019.</p></div><div><h3>Participants and setting</h3><p>Patients supported by VA ECMO for cardiogenic shock or cardiac arrest who are enrolled in the Australian national ECMO registry.</p></div><div><h3>Intervention</h3><p>The study compares a conservative oxygenation strategy (target arterial saturations 92–96%) with a liberal oxygenation strategy (target 97–100%).</p></div><div><h3>Main Outcome Measures</h3><p>The primary outcome is the number of intensive care unit (ICU)-free days for patients alive at day 60. Secondary outcomes include duration of mechanical ventilation, ICU and hospital mortality, the number of hypoxic episodes, neurocognitive outcomes, and health economic analyses. The 300-patient sample size enables us to detect a 3-day difference in ICU-free days at day 60, assuming a mean ICU-free days of 11 days, with a risk of type 1 error of 5% and power of 80%. Data will be analysed according to a predefined analysis plan. Findings will be disseminated in peer-reviewed publications.</p></div><div><h3>Conclusions</h3><p>This paper details the protocol and statistical analysis plan for the BLENDER trial, a registry-embedded, multicentre interventional trial comparing liberal and conservative oxygenation strategies in VA ECMO.</p></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 3","pages":"Pages 118-125"},"PeriodicalIF":2.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49711426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pfizer BNT 162b2 COVID-19 vaccine–induced fulminant myopericarditis: A case study","authors":"Natalie L. Montarello Cardiologist, MBBS, FRACP ,&nbsp;Hao Zheng Wong Intensivist, MBBS, FCICM ,&nbsp;Ashlee Jeffries Cardiology Registrar, MBBS ,&nbsp;Griffith B. Perkins Researcher in Immunology, BSc(Adv), PhD ,&nbsp;Pravin Hissaria Immunologist, MBBS, MD, DM, FRACP, FRCPA ,&nbsp;Michael B. Stokes Cardiologist, MBBS, FRACP ,&nbsp;Eamon Raith Intensivist, MBBS, MACCP, PhD ,&nbsp;Karen Teo Cardiologist, MBBS, FRACP, PhD ,&nbsp;Julie Bradley Cardiologist, MBBS FRACP, FCSANZ","doi":"10.1016/j.ccrj.2023.06.005","DOIUrl":"10.1016/j.ccrj.2023.06.005","url":null,"abstract":"<div><p>The use of mRNA COVID-19 vaccine can on rare occasions cause life-threatening, fulminant myopericarditis. This case report demonstrates previously reported benefit of early use of venoarterial extracorporeal membrane oxygenation mechanical assistance and supports the use of intravenous highly purified immunoglobulin pharmacotherapy to help achieve a good clinical outcome.</p></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 3","pages":"Pages 155-157"},"PeriodicalIF":2.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49004639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update in statistical analysis plan of the RENOVATE trial","authors":"I.S. Maia M.D. MSc,&nbsp;L. Kawano-Dourado M.D. Ph.D,&nbsp;L.P. Damiani Ph.D Statistics,&nbsp;M. Fitzgerald M.S. Ph.D Statistics,&nbsp;R.J. Lewis M.D. Ph.D,&nbsp;A.B. Cavalcanti M.D. Ph.D","doi":"10.1016/j.ccrj.2023.06.008","DOIUrl":"10.1016/j.ccrj.2023.06.008","url":null,"abstract":"","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 3","pages":"Pages 113-114"},"PeriodicalIF":2.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47964986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Further insights into the longer-term outcomes of patients experiencing in-hospital cardiac arrest","authors":"Gemma M. Pound PT, PhD Candidate,&nbsp;Carol L. Hodgson PT, PhD,&nbsp;Glenn M. Eastwood RN, PhD,&nbsp;Daryl A. Jones MD, PhD","doi":"10.1016/j.ccrj.2023.06.003","DOIUrl":"10.1016/j.ccrj.2023.06.003","url":null,"abstract":"","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 3","pages":"Page 115"},"PeriodicalIF":2.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46547100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Swallowing biomechanics in tracheostomised critically ill patients compared to age- and gender-matched healthy controls","authors":"Sanith S. Cheriyan MBBS, MSurg ,&nbsp;Mistyka S. Schar BSpPath, PhD ,&nbsp;Charmaine M. Woods B. Biotech (hons), PhD ,&nbsp;Shailesh Bihari FCICM, PhD ,&nbsp;Charles Cock FRACP, PhD ,&nbsp;Theodore Athanasiadis FRACS, PhD ,&nbsp;Taher I. Omari BSC (hons), PhD ,&nbsp;Eng H. Ooi FRACS, PhD","doi":"10.1016/j.ccrj.2023.05.007","DOIUrl":"10.1016/j.ccrj.2023.05.007","url":null,"abstract":"<div><h3>Objective</h3><p>The mechanistic effects of a tracheostomy on swallowing are unclear. Pharyngeal high-resolution manometry with impedance (P-HRM-I) is a novel swallow assessment tool providing quantifiable metrics. This study aimed to characterise swallowing biomechanics in tracheostomised critically ill (non-neurological) patients.</p></div><div><h3>Design</h3><p>Cohort study.</p></div><div><h3>Setting</h3><p>Australian tertiary hospital intensive care unit.</p></div><div><h3>Participants</h3><p>Tracheostomised adults, planned for decannulation.</p></div><div><h3>Main outcome measures</h3><p>Swallowing assessment using P-HRM-I, compared to healthy age- and gender-matched controls.</p></div><div><h3>Results</h3><p>In this tracheostomised cohort (n = 10), the Swallow Risk Index, a global measure of swallow function, was significantly elevated (<em>p</em> &lt; 0.001). At the upper oesophageal sphincter (UOS), hypopharyngeal intrabolus pressure and UOS integrated relaxation pressure were significantly elevated (control 0.65 mmHg [-1.02, 2.33] <em>v</em> tracheostomy 13.7 mmHg [10.4, 16.9], <em>P</em> &lt; 0.001; control −4.28 mmHg [-5.87, 2.69] <em>v</em> tracheostomy 12.2 mmHg [8.83, 15.6], <em>P</em> &lt; 0.001, respectively). Furthermore, UOS opening extent and relaxation time were reduced (control 4.83 mS [4.60, 5.07] v tracheostomy 4.33 mS [3.97, 4.69], P = 0.002; control 0.52 s [0.49, 0.55] v tracheostomy 0.41 s [0.37, 0.45], <em>P</em> &lt; 0.001, respectively). Total pharyngeal contractility (PhCI) measuring pharyngeal pressure generation was significantly elevated (control 199.5 mmHg cm.s [177.4, 221.6] <em>v</em> tracheostomy 326.5 mmHg cm.s [253.3, 399.7]; <em>P</em> = 0.001).</p></div><div><h3>Conclusion</h3><p>In a critically ill tracheostomised cohort, UOS dysfunction was the prevalent biomechanical feature, with elevated pharyngeal pressures. Pharyngeal weakness is not contributing to dysphagia in this cohort. Instead, elevated pharyngeal pressures may represent a compensatory mechanism to overcome the UOS dysfunction. Further studies to extend these findings may inform the development of timely and targeted rehabilitation.</p></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 2","pages":"Pages 97-105"},"PeriodicalIF":2.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43674566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How much do we throw away in the intensive care unit? An observational point prevalence study of Australian and New Zealand ICUs","authors":"Matthew H. Anstey MBBS, FCICM, FACEM, MPH, AFRACMA ,&nbsp;Louise Trent MBChB, FCICM, FANZCA, AFRACMA ,&nbsp;Deepak Bhonagiri MBBS, MD, FCICM ,&nbsp;Naomi E. Hammond RN, PhD ,&nbsp;Serena Knowles RN, PhD ,&nbsp;Forbes McGain FCICM FANZCA ,&nbsp;On behalf of The George Institute for Global Health and the Australian and New Zealand Intensive Care Society Clinical Trials Group","doi":"10.1016/j.ccrj.2023.05.004","DOIUrl":"10.1016/j.ccrj.2023.05.004","url":null,"abstract":"<div><h3>Objective</h3><p>During the current COVID pandemic, waste generation has been more evident with increased use of single use masks, gowns and other personal protective equipment. We aimed to understand the scale of waste generation, recycling rates and participation in Australian and New Zealand (ANZ) ICUs.</p></div><div><h3>Design</h3><p>This is a prospective cross-sectional point prevalence study, as part of the 2021 ANZICS Point Prevalence Program. Specific questions related to waste and sustainability practices were asked at the site and patient level.</p></div><div><h3>Setting and participants</h3><p>ANZ adult ICUs and their patients on the day of the study.</p></div><div><h3>Main outcome measures</h3><p>Amount of single use items disposed of per shift, as well as the engagement of the site with sustainability and recycling practices.</p></div><div><h3>Results</h3><p>In total, 712 patients (median number of patients per ICU = 17, IQR 11–30) from 51 ICUs across ANZ were included in our study; 55% of hospitals had a sustainability officer, and recycling paper (86%) and plastics (65%) were frequent, but metal recycling was limited (27%). Per patient bed space per 12-h shift there was recycling of less than 40% paper, glass, intravenous fluid bags, medication cups and metal instruments. A median of 10 gowns (IQR 3–19.5), 10 syringes (4.5–18) and gloves 30 (18–49) were disposed of per bed space, per 12-h shift. These numbers increased significantly when comparing patients with and without infection control precautions in place.</p></div><div><h3>Conclusions</h3><p>In ANZ ICUs, we found utilisation of common ICU consumables to be high and associated with low recycling rates. Interventions to abate resource utilisation and augment recycling are required to improve environmental sustainability in intensive care units.</p></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 2","pages":"Pages 78-83"},"PeriodicalIF":2.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43442547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential role for extracorporeal membrane oxygenation cardiopulmonary resuscitation (E-CPR) during in-hospital cardiac arrest in Australia: A nested cohort study","authors":"G. Pound PT PhD Candidate ,&nbsp;G.M. Eastwood RN PhD ,&nbsp;D. Jones MD PhD ,&nbsp;C.L. Hodgson PT PhD","doi":"10.1016/j.ccrj.2023.05.006","DOIUrl":"https://doi.org/10.1016/j.ccrj.2023.05.006","url":null,"abstract":"<div><h3>Objective</h3><p>This study aims to evaluate the characteristics and outcomes of patients who fulfilled extracorporeal membrane oxygenation cardiopulmonary resuscitation (E-CPR) selection criteria during in-hospital cardiac arrest (IHCA).</p></div><div><h3>Design</h3><p>This is a nested cohort study.</p></div><div><h3>Setting</h3><p>Code blue data were collected across seven hospitals in Australia between July 2017 and August 2018.</p></div><div><h3>Participants</h3><p>Participants who fulfilled E-CPR selection criteria during IHCA were included.</p></div><div><h3>Main outcome measures</h3><p>Return of spontaneous circulation and survival and functional outcome at hospital discharge. Functional outcome was measured using the modified Rankin scale, with scores dichotomised into good and poor functional outcome.</p></div><div><h3>Results</h3><p>Twenty-three (23/144; 16%) patients fulfilled E-CPR selection criteria during IHCA, and 11/23 (47.8%) had a poor outcome. Patients with a poor outcome were more likely to have a non-shockable rhythm (81.8% vs. 16.7%; <em>p</em> = 0.002), and a longer duration of CPR (median 12.5 [5.5, 39.5] vs. 1.5 [0.3, 2.5] minutes; <em>p</em> &lt; 0.001) compared to those with a good outcome. The majority of patients (18/19 [94.7%]) achieved sustained return of spontaneous circulation within 15 minutes of CPR. All five patients who had CPR &gt;15 minutes had a poor outcome.</p></div><div><h3>Conclusion</h3><p>Approximately one in six IHCA patients fulfilled E-CPR selection criteria during IHCA, half of whom had a poor outcome. Non-shockable rhythm and longer duration of CPR were associated with poor outcome. Patients who had CPR for &gt;15 minutes and a poor outcome may have benefited from E-CPR. The feasibility, effectiveness and risks of commencing E-CPR earlier in IHCA and among those with non-shockable rhythms requires further investigation.</p></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"25 2","pages":"Pages 90-96"},"PeriodicalIF":2.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49713690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}