Giornale Italiano Di Dermatologia E Venereologia最新文献_第5页

Spastic quadriplegia following intradermal use of hydrogen peroxide in the tardive curettage procedure for the treatment of a giant congenital nevus. 迟发性刮除术中使用过氧化氢治疗巨大先天性痣后的痉挛性四肢瘫痪。

IF 2

Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 DOI: 10.23736/S0392-0488.16.05231-7

Andrea Molinelli, Emanuele Cozzani, Martina Burlando, Pierluigi Santi, Aurora Parodi, Francesco Ventura

引用次数: 1

Effectiveness of a combination of salicylic acid-based products for the treatment of mild comedonal-papular acne: a multicenter prospective observational study. 基于水杨酸的产品组合治疗轻度粉刺丘疹痤疮的有效性:一项多中心前瞻性观察研究。

IF 2

Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 Epub Date: 2020-10-16 DOI: 10.23736/S0392-0488.20.06751-6

Vincenzo Bettoli, Giuseppe Micali, Giuseppe Monfrecola, Stefano Veraldi

{"title":"Effectiveness of a combination of salicylic acid-based products for the treatment of mild comedonal-papular acne: a multicenter prospective observational study.","authors":"Vincenzo Bettoli, Giuseppe Micali, Giuseppe Monfrecola, Stefano Veraldi","doi":"10.23736/S0392-0488.20.06751-6","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06751-6","url":null,"abstract":"Background: The most common therapeutic approach to acne is a combined treatment of retinoid and benzoyl peroxide, with oral antibiotics recommended for moderate-to-severe cases. These kinds of therapies often lead to adverse reactions, leading to the request for new therapeutic options. Recently, the combined use of three salicylic acid-based products for the topical treatment of acne has been related to a significant improvement in acne lesions.Methods: A multicenter prospective observational study was carried out on patients with a diagnosis of mild comedonal-papular facial acne to provide new evidence on the clinical effectiveness, tolerability and acceptability of three salicylic acid-based products for the topical treatment of acne in the daily clinical practice. Clinical effectiveness on lesions improvement, the evaluation of personal discomfort related to acne and the assessment of overall clinical outcome were the primary endpoints. Treatment acceptability and tolerability were also evaluated.Results: The treatment with the three salicylic acid-based products has been related to a significant improvement on acne lesions over 8 weeks of treatment, along with a reduction of personal discomfort related to acne and an improvement on lesions appearance. The products have also shown good acceptability and tolerability.Conclusions: The results of this observational study support the effective and well-tolerated use of a combined treatment with three salicylic acid-based products for the topical treatment of acne.","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"744-748"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38503324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Postacne scarring: which factors are involved? 痤疮后疤痕:涉及哪些因素?

IF 2

Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 Epub Date: 2019-07-12 DOI: 10.23736/S0392-0488.19.06154-6

Ersilia Tolino, Nevena Skroza, Ilaria Proietti, Nicoletta Bernardini, Veronica Balduzzi, Alessia Anzalone, Giuseppe LA Torre, Anna Marchesiello, Alessandra Mambrin, Concetta Potenza

引用次数: 1

Tocilizumab and its usage for skin diseases. 托珠单抗及其在皮肤病中的应用。

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Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 DOI: 10.23736/S0392-0488.20.06772-3

L. Mastorino, G. Avallone, P. Dapavo, M. Merli, A. Agostini, D. Grandinetti, M. Fierro, P. Quaglino, S. Ribero

引用次数: 0

Familial lupus panniculitis: two cases, same diagnosis, what evolution? 家族性狼疮性睫状体炎:2例，诊断相同，进展如何?

IF 2

Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 Epub Date: 2019-01-09 DOI: 10.23736/S0392-0488.18.06151-5

Elisa Molinelli, Anna Campanati, Valerio Brisigotti, Federico Diotallevi, Giulia Radi, Stefano Racchini, Mirella Giangiacomi, Annamaria Offidani

引用次数: 0

Acne fulminans. 痤疮闪电。

IF 2

Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 Epub Date: 2020-10-21 DOI: 10.23736/S0392-0488.20.06711-5

Federica Dall'oglio, Davide F Puglisi, Maria R Nasca, Giuseppe Micali

{"title":"Acne fulminans.","authors":"Federica Dall'oglio, Davide F Puglisi, Maria R Nasca, Giuseppe Micali","doi":"10.23736/S0392-0488.20.06711-5","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06711-5","url":null,"abstract":"Acne fulminans (AF) is a rare and severe form of inflammatory acne presenting clinically with an abrupt outburst of painful, hemorrhagic pustules and ulceration, that may or may not be associated with systemic symptoms, such as fever, polyarthritis, and laboratory abnormalities. It typically affects male teenagers with a pre-existing acne. Although the pathogenetic mechanism has not been established yet, a role of genetic, abnormal immunologic response, drugs intake, hormonal imbalance and viral infection, as causal factors, has been identified. AF may occur as a single disease or may be associated with other disorders. Traditionally, AF has been classified, on the basis of the presence of systemic involvement, in \"acne fulminans\" and acne fulminans \"sine fulminans,\" when no systemic involvement is present. Recently, four clinical variants have been proposed: acne fulminans with systemic symptoms (AF-SS), acne fulminans without systemic symptoms (AF-WOSS), isotretinoin-induced acne fulminans with systemic symptoms (IIAF-SS), isotretinoin-induced acne fulminans without systemic symptoms (IIAF-WOSS). The diagnosis of AF is usually based on clinical history and physical examination. No specific laboratory abnormalities are generally found. In selected cases, biopsy and/or radiologic imaging are helpful for a correct diagnosis. The treatment significantly differs from severe acne according to severity of clinical presentation and possible systemic involvement. Currently, systemic corticosteroids (prednisolone) and retinoids (isotretinoin) represent the first choice of treatment. Dapsone, cyclosporine A, methotrexate, azathioprine, levamisole, and biological agents such as anakinra, infliximab, adalimumab may be considered as alternative therapies in selected cases. Adjunctive topical and physical therapies may also be considered.","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"711-718"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38517952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Helicobacter pylori infection and dermatologic diseases: time to turn the page? 幽门螺杆菌感染与皮肤病:是时候翻开新的一页了?

IF 2

Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 Epub Date: 2020-11-23 DOI: 10.23736/S0392-0488.20.06855-8

Alessandro Adriani, Giorgio M Saracco, Rinaldo Pellicano

引用次数: 0

Atopic dermatitis in young adult Italian males: persistent and adult-onset varieties did not clinically differ, as for allergological variables. 在年轻成年意大利男性特应性皮炎:持续和成人发病的品种没有临床差异，作为过敏症变量。

IF 2

Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 Epub Date: 2019-01-16 DOI: 10.23736/S0392-0488.18.06239-9

Vito Ingordo, Simone Cazzaniga, Luigi Naldi, Salvatore Perrucci, Mauro Barbierato, Filippo Crociata, Francesco Cusano

{"title":"Atopic dermatitis in young adult Italian males: persistent and adult-onset varieties did not clinically differ, as for allergological variables.","authors":"Vito Ingordo, Simone Cazzaniga, Luigi Naldi, Salvatore Perrucci, Mauro Barbierato, Filippo Crociata, Francesco Cusano","doi":"10.23736/S0392-0488.18.06239-9","DOIUrl":"https://doi.org/10.23736/S0392-0488.18.06239-9","url":null,"abstract":"Background: The prevalence of adult atopic dermatitis (AD) in general population range from 2.6% to 8% according to objective diagnosis in selected groups of people. The adult-onset AD is the clinical form arising de novo in adulthood. The aim of this study was to detect retrospectively the prevalence of AD in Italian general population, examining a sample of young Italian males affected by AD, which was representative of people of same sex and age, and to point out the clinical and allergological differences between the persistent and adult-onset form.Methods: 198,730 potential male conscripts were visited in Italian Navy and Air Force Recruitment's Centers in Taranto to evaluate their fitness to recruitment. All the young men who showed eczema were referred to Italian Navy Hospital. The diagnosis of AD was stated according to Hanifin and Rajka's criteria. All the patients were patch and prick tested.Results: One hundred twenty-four cases of AD were diagnosed, with a prevalence of 6.2 cases for 10,000 subjects (95% CI: 5.2-7.4). The subjects with the persistent form were 68 (75.6%; 95% CI: 66.7-84.4) vs. 26 patients with the adult-onset form (21.0%; 95% CI: 13.8-28.1). No statistical difference in clinical and allergological variables was showed between the persistent and adult-onset AD.Conclusions: The prevalence of adult AD in a large sample of young males - representative of the general population of same age and sex - is appreciably lower than the rates previously reported. No clinical feature or allergological variable discriminate between persistent vs. adult-onset varieties.","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"724-732"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36870906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Healthy Hands: a pilot study for the prevention of chronic hand eczema in healthcare workers of an Italian University Hospital. 健康的手:预防慢性手湿疹在意大利大学医院医护人员的试点研究。

IF 2

Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 Epub Date: 2019-06-12 DOI: 10.23736/S0392-0488.19.06220-5

Giulia Gasparini, Luca Carmisciano, Irene Giberti, Franca Murgioni, Aurora Parodi, Rosella Gallo

{"title":"Healthy Hands: a pilot study for the prevention of chronic hand eczema in healthcare workers of an Italian University Hospital.","authors":"Giulia Gasparini, Luca Carmisciano, Irene Giberti, Franca Murgioni, Aurora Parodi, Rosella Gallo","doi":"10.23736/S0392-0488.19.06220-5","DOIUrl":"https://doi.org/10.23736/S0392-0488.19.06220-5","url":null,"abstract":"Background: Healthcare workers are at risk for occupational chronic hand eczema (CHE) because of frequent handwashing and prolonged use of occlusive gloves. Prevention programs based on skin care education have been shown to be beneficial. We developed and assessed the efficacy of a skin care educational intervention for healthcare workers of our hospital.Methods: The intervention consisted of two sessions, one week apart, each divided in a theoretical and a practical part, focusing on the skin barrier, types of eczema, risk factors for CHE, hand hygiene measures respectful of the skin, proper use of protective gloves and emollient creams. Its efficacy was assessed by a questionnaire, administered before and after the intervention, investigating the participants' knowledge of risk factors for CHE and risk behaviors.Results: Twenty-three subjects, mostly (65.2%) nurses, took part in the intervention; 60.9% had a self-reported atopic background and 65.2% participants reported a history of CHE. The intervention improved significantly the participants' knowledge on CHE risk factors, i.e. frequent handwashing (P=0.023), surgical scrubbing (P=0.016) and prolonged glove wearing (P=0.022). The frequency of hand washing was significantly reduced (P=0.022). The participants gave a positive unanimous feedback.Conclusions: Our intervention was effective, by significantly improving the participants' knowledge and by inducing significant behavioral changes. Improving the formulation of alcoholic hand rubs may be a key factor to encourage their use. Coexisting nonoccupational risk behaviors are just as important in the prevention of CHE.","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"760-763"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37326083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Detection of IgE autoantibodies in mucous membrane pemphigoid and their association with disease severity. 类天疱疮粘膜IgE自身抗体的检测及其与疾病严重程度的关系。

IF 2

Giornale Italiano Di Dermatologia E Venereologia Pub Date : 2020-12-01 Epub Date: 2018-10-04 DOI: 10.23736/S0392-0488.18.06167-9

Laura Corti, Daniele Fanoni, Luigia Venegoni, Simona Muratori, Sebastiano Recalcati, Emilio Berti

{"title":"Detection of IgE autoantibodies in mucous membrane pemphigoid and their association with disease severity.","authors":"Laura Corti, Daniele Fanoni, Luigia Venegoni, Simona Muratori, Sebastiano Recalcati, Emilio Berti","doi":"10.23736/S0392-0488.18.06167-9","DOIUrl":"https://doi.org/10.23736/S0392-0488.18.06167-9","url":null,"abstract":"Background: Mucous membrane pemphigoid (MMP) is an autoimmune disease characterized by scarring lesions at mucosal sites. Although the pathogenic role of specific IgG and/or IgA has been already demonstrated and the detection of these immunoglobulins is a criterion in the diagnosis of MMP, little is known about IgE role in this disease. Therefore, the main purpose of this study was to assess the presence of circulating and tissue bound IgE in patients with MMP and their possible correlations with clinical presentation and disease course.Methods: We conducted a retrospective study on 29 patients affected by MMP, recruited from a single center. Direct and indirect immunofluorescence studies were assessed to analyze the presence of specific IgE directed against the basal membrane zone. For each patient, fluorescence data were compared to clinical features.Results: Linear deposits of C3, IgG and IgA were present in 86.2%, 62% and 37.9% of cases respectively, while IgE linear deposits were detected in 17 out of 29 patients (58.6%) including one case with isolated IgE positivity. Circulating IgE and IgA anti-BMZ were present in 7 (24.1%) and 5 (17.2%) patients, respectively. Both the presence of circulating IgA and of tissue bound IgE deposits correlated with disease activity index (P<0.014).Conclusions: Our results demonstrated the presence of IgE autoantibodies in MMP, particularly in more severe cases. Thus, IgE detection may represent an additional useful diagnostic tool in this disease.","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"754-759"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36557394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5