Neuropsychiatry最新文献_第4页

Bridging neuroscience and clinical psychology: cognitive behavioral and psychophysiological models in the evaluation and treatment of Gilles de la Tourette syndrome. 神经科学与临床心理学的桥梁：评估和治疗吉勒-德拉图雷特综合征的认知行为学和心理生理学模型。

Neuropsychiatry Pub Date : 2013-02-01 DOI: 10.2217/npy.12.70

Marc E Lavoie, Julie Leclerc, Kieron P O'Connor

引用次数: 0

Barriers in the diagnosis and treatment of depression in women in the USA: where are we now? 美国妇女抑郁症诊断和治疗的障碍：我们现在在哪里？

Neuropsychiatry Pub Date : 2013-02-01 DOI: 10.2217/npy.12.76

Jean Y Ko, Sherry L Farr, Patricia M Dietz

引用次数: 0

Cyclothymic disorder in youth: why is it overlooked, what do we know and where is the field headed? 青年周期胸腺障碍:为什么它被忽视，我们知道什么，以及该领域的发展方向?

Neuropsychiatry Pub Date : 2012-12-01 DOI: 10.2217/npy.12.64

Anna R Van Meter, Eric A Youngstrom

{"title":"Cyclothymic disorder in youth: why is it overlooked, what do we know and where is the field headed?","authors":"Anna R Van Meter, Eric A Youngstrom","doi":"10.2217/npy.12.64","DOIUrl":"https://doi.org/10.2217/npy.12.64","url":null,"abstract":"Cyclothymic disorder is a chronic and impairing subtype of bipolar disorder, largely neglected in pediatric research. Consequently, it is rarely diagnosed clinically despite potentially being the most prevalent form of bipolar disorder. Lack of attention has added to confusion about the diagnosis and clinical presentation of cyclothymic disorder. In pediatric studies, cyclothymic disorder is commonly grouped with 'subthreshold' presentations of bipolar disorder under the undifferentiated label 'bipolar disorder not otherwise specified'. However, research indicates that cyclothymic disorder can be reliably distinguished from the other forms of bipolar disorder and from other childhood disorders. Importantly, cyclothymic disorder may be a diathesis for more acute presentations of bipolar disorder, warranting a prominent role in dimensional models of mood and psychopathology. Current evidence suggests that cyclothymic disorder has the potential to make unique contributions to our understanding of the risk factors and outcomes associated with bipolar disorder. This potential has yet to be fully realized, limiting our knowledge and ability to intervene in a meaningful way with youth who are exhibiting symptoms of a major mood disorder. Including cyclothymic disorder in future research studies of children - particularly longitudinal outcome studies - is essential for understanding the developmental trajectory of bipolar spectrum disorders and learning how to accurately diagnosis and treat the full spectrum of bipolar disorders.","PeriodicalId":49013,"journal":{"name":"Neuropsychiatry","volume":"2 6","pages":"509-519"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/npy.12.64","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40238147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Clinical utility of magnetic resonance spectroscopy to enhance diagnosis of HIV-associated mild neurocognitive disorder. 磁共振波谱增强hiv相关轻度神经认知障碍诊断的临床应用。

Neuropsychiatry Pub Date : 2012-10-01 DOI: 10.2217/npy.12.50

Karl Goodkin, Jeffry R Alger, Andrew A Maudsley, Varan Govind, Sulaiman Sheriff, Jingjing Michele Zhang

引用次数: 2

Elevated rates of ADHD in mothers of children with comorbid ADHD and epilepsy. 合并多动症和癫痫的儿童的母亲患多动症的比例升高。

Neuropsychiatry Pub Date : 2012-10-01 DOI: 10.2217/npy.12.53

Joseph Gonzalez-Heydrich, Hesham M Hamoda, Laura Luna, Sneha Rao, James McClendon, Peter Rotella, Deborah Waber, Katherine Boyer, Steven V Faraone, Jane Whitney, Danielle Guild, Joseph Biederman

{"title":"Elevated rates of ADHD in mothers of children with comorbid ADHD and epilepsy.","authors":"Joseph Gonzalez-Heydrich, Hesham M Hamoda, Laura Luna, Sneha Rao, James McClendon, Peter Rotella, Deborah Waber, Katherine Boyer, Steven V Faraone, Jane Whitney, Danielle Guild, Joseph Biederman","doi":"10.2217/npy.12.53","DOIUrl":"10.2217/npy.12.53","url":null,"abstract":"OBJECTIVES: To describe the prevalence of ADHD in mothers of children with comorbid ADHD and epilepsy (ADHD+E) and to compare ADHD symptoms in mothers with (Fam(+)) and without (Fam(-)) additional relative(s) with epilepsy. PATIENTS & METHODS: Mothers (n = 16) of children with ADHD+E were assessed by the Kiddie Schedule for Affective Disorders and Schizophrenia for School Age Children ADHD module and the ADHD Rating Scale IV. Information was collected on the presence (Fam(+)) or absence (Fam(-)) of first- or second-degree relatives with epilepsy in the sample. RESULTS: A total of 50% of mothers met the DSM-IV criteria for ADHD. ADHD was more prevalent in Fam(+) mothers (80%) compared with Fam(-) mothers (36%; p = 0.14). Fam(+) mothers had more current hyperactivity symptoms than Fam(-) mothers (p = 0.002), higher current ADHD severity (p = 0.02) and higher ADHD Rating Scale IV hyperactivity scores (p = 0.008). CONCLUSION: The prevalence of ADHD in mothers of children with ADHD+E is elevated in this pilot study, suggesting that ADHD symptoms in children with epilepsy and their mothers reflects shared familial genetic or environmental risks, potentially resulting in a higher prevalence of both disorders among family members. This is a pilot study and larger controlled studies are warranted.","PeriodicalId":49013,"journal":{"name":"Neuropsychiatry","volume":"2 5","pages":"385-391"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565178/pdf/nihms434231.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31228839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Substance-use disorders in adolescents and adults with ADHD: focus on treatment. 青少年和成人ADHD患者的物质使用障碍:关注治疗。

Neuropsychiatry Pub Date : 2012-08-01 DOI: 10.2217/npy.12.39

Timothy E Wilens, Nicholas R Morrison

引用次数: 45

Psychotropic effects of antimicrobials and immune modulation by psychotropics: implications for neuroimmune disorders. 抗微生物药物的精神作用和精神药物的免疫调节:对神经免疫疾病的影响。

Neuropsychiatry Pub Date : 2012-08-01 DOI: 10.2217/npy.12.41

Demian Obregon, Ellisa Carla Parker-Athill, Jun Tan, Tanya Murphy

引用次数: 17

Advances in the treatment of pediatric obsessive-compulsive d-cycloserine with exposure and response prevention. 用暴露和反应预防法治疗小儿强迫症的进展。

Neuropsychiatry Pub Date : 2012-08-01 DOI: 10.2217/npy.12.38

Joseph F McGuire, Adam B Lewin, Daniel A Geller, Ashley Brown, Kesley Ramsey, Jane Mutch, Andrew Mittelman, Jamie Micco, Cary Jordan, Sabine Wilhelm, Tanya K Murphy, Brent J Small, Eric A Storch

{"title":"Advances in the treatment of pediatric obsessive-compulsive d-cycloserine with exposure and response prevention.","authors":"Joseph F McGuire, Adam B Lewin, Daniel A Geller, Ashley Brown, Kesley Ramsey, Jane Mutch, Andrew Mittelman, Jamie Micco, Cary Jordan, Sabine Wilhelm, Tanya K Murphy, Brent J Small, Eric A Storch","doi":"10.2217/npy.12.38","DOIUrl":"10.2217/npy.12.38","url":null,"abstract":"Exposure-based cognitive-behavioral therapy and serotonin reuptake inhibitor medications are efficacious treatment options for the management of pediatric obsessive-compulsive disorder. Despite established efficacy, many youths receiving either therapy remain symptomatic after acute treatment. Regardless of the rationale for persistent symptoms, a clear need emerges for treatment options that restore functioning efficiently to symptomatic youths. One innovative approach builds upon the identified role of NMDA receptors in the fear extinction process. Instead of breaking existing connections during fear extinction, new associations develop that eventually predominate over prior associations. Recent investigations have explored augmenting exposure-based cognitive-behavioral therapy with the NMDA partial agonist d-cycloserine, with preliminary results demonstrating expedited treatment gains and moderately larger effects above exposure and response prevention therapy alone. A large randomized clinical trial is underway to evaluate the efficacy and efficiency of this therapeutic combination in pediatric obsessive-compulsive disorder. Results from this trial may translate into improved management practices.","PeriodicalId":49013,"journal":{"name":"Neuropsychiatry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808983/pdf/nihms-406071.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40279864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Personalizing behavioral interventions: the case of late-life depression. 个性化行为干预:晚年抑郁症的案例。

Neuropsychiatry Pub Date : 2012-04-01 DOI: 10.2217/npy.12.15

Patricia A Arean

引用次数: 11

Investigating facets of personality in adult pathological gamblers with ADHD. 调查患有ADHD的成年病态赌徒的人格方面。

Neuropsychiatry Pub Date : 2012-04-01 DOI: 10.2217/npy.12.11

Margarit Davtian, Rory C Reid, Timothy W Fong

{"title":"Investigating facets of personality in adult pathological gamblers with ADHD.","authors":"Margarit Davtian, Rory C Reid, Timothy W Fong","doi":"10.2217/npy.12.11","DOIUrl":"https://doi.org/10.2217/npy.12.11","url":null,"abstract":"The present study explored facets of personality in a sample of pathological gamblers with ADHD (n = 52) and without ADHD (n = 43). Participants were assessed for psychopathology and gambling disorders using the Mini International Neuropsychiatric Interview, the National Opinion Research Center DSM Screen for Gambling Problems, and the Adult ADHD Self-Report Scale. Facets of personality were assessed using the NEO Personality Inventory-Revised. Group differences emerged across several facets of personality when analyzed using multivariate statistics. Although both groups experienced difficulties in several areas compared with norming data (e.g., greater depression, higher impulsivity, lower self-esteem and lower self-discipline), these facets of personality were more pronounced in pathological gamblers with ADHD. Most notable among these differences are tendencies for gamblers with ADHD to experience greater levels of emotional instability, interpersonal sensitivity and stress proneness. Pathological gamblers with ADHD also appear to experience lower self-esteem, greater difficulty being assertive and lower levels of self-discipline. Surprisingly, both groups were comparable on facets of impulsivity. These findings suggest that pathological gamblers diagnosed with adult ADHD may experience additional challenges compared with pathological gamblers without ADHD.","PeriodicalId":49013,"journal":{"name":"Neuropsychiatry","volume":"2 2","pages":"163-174"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/npy.12.11","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30776673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21