Journal of Occupational Medicine and Toxicology最新文献

{"title":"Associations between pesticide exposure and hepatobiliary disease among agricultural workers in the Northeastern region of Thailand: a cross-sectional study.","authors":"Kulthida Y Kopolrat, Sunisa Chaiklieng, Paiboon Sithithaworn, Pornnapa Suggaravetsiri, Vichai Pruktharathikul, Kannika Trinnawoottipong","doi":"10.1186/s12995-025-00470-9","DOIUrl":"10.1186/s12995-025-00470-9","url":null,"abstract":"<p><strong>Background: </strong>Occupational exposure to pesticides has been linked to hepatobiliary diseases, particularly liver cancer and cholangiocarcinoma (CCA). In Thailand, pesticides are crucial for agriculture, enhancing crop protection and yields. This study aimed to determine the association between pesticide exposure and the prevalence of hepatobiliary diseases among agricultural workers in Northeastern Thailand.</p><p><strong>Methods: </strong>The abdominal ultrasonographic findings of the CCA risk population were retrieved from the Isan cohort. Biological monitoring data on pesticide exposure were collected via serum cholinesterase testing from 8 provinces in Northeast Thailand, including Khon Kaen, Roi Et, Udon Thani, Nong Bua Lamphu, Kalasin, Buriram, Nakhon Phanom, and Sakon Nakhon provinces during 2016-2024. Data was analyzed using descriptive and inferential statistics with the STATA version 11.0 program.</p><p><strong>Results: </strong>Of the 917 agricultural workers, the average age was 54.88 years (SD = 8.53), 552 were female (60.20%), and 365 were male (39.80%). The highest prevalence of hepatobiliary disease (46.03%) and abnormal serum cholinesterase levels (89.42%) among agricultural workers was observed in Sakon Nakhon province. The prevalence of abnormal serum cholinesterase in males (84.11%) was higher than in females (65.76%) (p < 0.001). Multiple logistic regression analyses showed a significantly positive association between abnormal serum cholinesterase levels and hepatobiliary diseases among agricultural workers (OR_adj = 3.64, 95% CI = 2.46-5.38, p < 0.001).</p><p><strong>Conclusions: </strong>Our study highlights the association between pesticide exposure, indicated by abnormal serum cholinesterase levels, and an increased risk of hepatobiliary diseases. This finding underscores the importance of targeted interventions and public health policies that focus on educating agricultural workers on safe pesticide handling, promoting awareness campaigns, and implementing surveillance efforts to reduce exposure and mitigate the burden of hepatobiliary diseases, particularly in high-risk populations.</p>","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"24"},"PeriodicalIF":2.7,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12341068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burnout and coping mechanisms among Sudanese healthcare workers during the ongoing Sudan war: a cross-sectional study.","authors":"Muhannad Bushra Masaad Ahmed, Ahmed Balla M Ahmed, Salma Alrawa, Ludn Emad Ebrahim Mustafa, Mahmoud Elsadig Mahmoud Ali, Mohammed Osman Omer Abdalla, Sohaib Mohammed Mokhtar Ahmed","doi":"10.1186/s12995-025-00472-7","DOIUrl":"10.1186/s12995-025-00472-7","url":null,"abstract":"<p><strong>Background: </strong>During the Sudan war, healthcare workers have encountered extraordinary challenges, including physical assaults and the immense strain of delivering care with critically limited resources. These conditions are likely to intensify burnout among healthcare professionals. This study aimed to determine the prevalence of burnout among Sudanese healthcare workers and investigate the coping mechanisms they employ during the ongoing conflict.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among Sudanese healthcare workers using the standardized Maslach Burnout Inventory - Human Services Survey (MBI-HSS). Multivariable linear regression analysis was conducted to identify independent predictors of burnout domains. A significance level of p < 0.05 was considered for all statistical tests.</p><p><strong>Results: </strong>High emotional exhaustion was reported by 13.7% of participants, while 56.5% experienced high depersonalization, and only 4.4% reported low levels of personal accomplishment. The leading coping mechanism was talking with friends and family, adopted by 28.8% of participants, while 15.5% turned to spiritual or religious practices.</p><p><strong>Conclusion: </strong>Sudanese healthcare workers demonstrate high levels of burnout, particularly in the depersonalization domain, with talking to friends and family being the most commonly used coping mechanism. Future research is needed to explore the unique stressors faced by healthcare workers in conflict-affected settings like ours.</p>","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"23"},"PeriodicalIF":2.7,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12312341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of cold exposure on shift working seafood handlers in Northern Norway: a comparative analysis across work shifts.","authors":"Phong K T Chau, Tiril Schjølberg, Mina Baarnes Eriksen, Anne-Mari Gjestvang Moe, Pål Graff, Fred Haugen","doi":"10.1186/s12995-025-00469-2","DOIUrl":"10.1186/s12995-025-00469-2","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the impact of occupational thermal exposure on shift workers, specifically whether cold exposure elicits distinct physiological responses and thermoregulatory recovery across different tasks and shift types.</p><p><strong>Methods: </strong>Observational study at two factories processing prawns in Northern Norway in which 32 shift-working seafood handlers with different task responsibilities were followed for a single shift (morning, evening, night). The participants answered questionnaires regarding thermal exposures at work and related symptoms; these were compared to answers from 12 administration workers. Personal thermal loggers measured the range of temperature exposures associated with four different seafood handler work tasks. Pre- and post-shift plasma levels of FGF21, GDF15 and cytokines were analysed using immunoassays. As a proxy for thermoregulatory response across different shift types, hand temperature was measured repeatedly before and after breaks using a thermal imaging camera.</p><p><strong>Results: </strong>Most seafood handlers reported subjective impact from cold exposure. Cold working conditions of ≤ 10 ℃ were measured across all shifts and three different seafood handling tasks. The morning shift-seafood handlers displayed lower plasma FGF21 post-shift vs. pre-shift; the evening and night shifts showed no difference. GDF15 levels remained unchanged regardless of shift types but were positively correlated with age. Night shift was associated with increased plasma IL6 post-shift vs. pre-shift. Thermoregulatory responses showed a positive linear relationship with break duration but did not differ between shifts.</p><p><strong>Conclusions: </strong>The findings suggest that exposure levels are closely linked to specific tasks and shifts, with thermoregulatory responses varying by task type and time of day.</p>","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"22"},"PeriodicalIF":2.9,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12183870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Sowing seeds of awareness: a cross-sectional analysis of mental health literacy and help-seeking in Irish farmers.","authors":"Siobhan O'Connor, Anna Donnla O'Hagan, Joseph Firnhaber, Branagh R O'Shaughnessy, John McNamara, Gavin Breslin, Sinead O'Keeffe, Sandra M Malone","doi":"10.1186/s12995-025-00466-5","DOIUrl":"10.1186/s12995-025-00466-5","url":null,"abstract":"","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"21"},"PeriodicalIF":2.9,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12168309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Firefighting, other protective service occupations and prostate cancer risk: a pooled analysis of three case-control studies.","authors":"Wendy Bijoux, Marie-Élise Parent, Hugues Richard, Gemma Castaño-Vinyals, Marina Pollán, Manolis Kogevinas, Kurt Straif, Florence Menegaux","doi":"10.1186/s12995-025-00464-7","DOIUrl":"10.1186/s12995-025-00464-7","url":null,"abstract":"<p><p>BACKGROUND: Prostate cancer (PCa) is the most frequent incident cancer among males in industrialized countries, but little is known about its aetiology. A role for occupational exposures is suggested. Occupational exposure as a firefighter, a protective service occupation (PSO), is classified as carcinogenic to humans by the International Agency for Research on Cancer, with limited evidence in humans for PCa. We studied the association between PSO and PCa risk considering tumour aggressiveness and screening practices. METHODS: The EPIdemiological study of Prostate Cancer (EPICAP), the Prostate cancer & Environment Study (PROtEuS) and the MultiCase-Control study in common tumours in Spain (MCC-Spain) are population-based case-control studies, conducted respectively in France, Canada, Spain, in 2005–2014 in men ≤ 85 years old, including overall 3,859 incident cases and 4,359 controls frequency-matched on age. Participants were interviewed face-to-face using general and occupational questionnaires covering all jobs held in career, coded according to the 1988 International Standard Classification of Occupations. Unconditional logistic regressions estimated associations between PSO and PCa, after adjusting for potential confounders. Two sets of analyses were conducted, without and with consideration of screening. The latter is believed to yield the main findings since less subject to detection bias. RESULTS: When restricting controls to those recently screened, men employed as firefighters ≥ 10 years had increased risk (OR (Odds ratio) = 2.01 [95% confidence interval] [1.02; 3.97]) of non-aggressive PCa. Positive associations for non-aggressive PCa among men employed < 10 years as police officers (OR = 2.53 [1.07; 5.96]) and police inspectors and detectives (OR = 6.75 [1.47; 30.96]) were observed. Very few cases in PSO were characterized by aggressive tumours. CONCLUSIONS: Findings from this large population-based study corroborate the higher PCa risk previously reported among firefighters, but only for non-aggressive tumours. Screening practices had a substantial impact on risk estimates. Future studies should investigate specific exposures, and account for PCa aggressiveness and individual screening patterns. </p>","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"20"},"PeriodicalIF":3.2,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12150489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orofacial pain and oral health-related quality of life in woodwind and cello musicians in German orchestras: an online based questionnaire study.","authors":"Felix Marschner, Armin Sokolowski, Alwin Sokolowski, Jana Biermann, Annette Wiegand","doi":"10.1186/s12995-025-00467-4","DOIUrl":"10.1186/s12995-025-00467-4","url":null,"abstract":"<p><strong>Background: </strong>Occupational factors and the type of instrument played may influence physical and psychological health, affecting oral health-related quality of life (OHRQoL). This study assessed the prevalence of orofacial pain, sleep bruxism, stress, and OHRQoL among woodwind musicians (oboe, flute, clarinet, bassoon) in German professional orchestras, compared to cellists.</p><p><strong>Methods: </strong>A standard online questionnaire was sent to all 129 German professional orchestras. Orofacial pain, stress, and sleep-related issues in the past 30 days were evaluated. The German version of the Oral Health Impact Profile-14 (OHIP-14) assessed OHRQoL. Logistic and linear regression analyses were performed (statistical significance p < 0.05).</p><p><strong>Results: </strong>A total of 243 musicians were included. Orofacial pain was reported by 35.8%, sleep bruxism by 63.0%, and stress by 88.9% of the participant. Orofacial pain was significantly associated with female gender (p = 0.027; odds ratio [OR] = 2.09, 95% confidence interval [CI]: 1.09-4.02), frequent sleep bruxism (p = 0.013; OR = 2.65, 95%-CI: 1.23-5.69), frequent stress (p = 0.002; OR = 3.19, 95%-CI: 1.53-6.63), and difficulties initiating sleep after evening shifts (p = 0.003; OR = 2.90, 95%-CI: 1.45-5.80), but not with the instrument played. OHIP-14 scores did not differ significantly between instrument groups (p = 0.629), but correlated with orofacial pain (p < 0.001), sleep bruxism (p < 0.001), stress (p = 0.002), and sleep difficulties (p = 0.040).</p><p><strong>Conclusions: </strong>Orofacial pain and sleep bruxism are common among professional musicians, with stress-related factors playing a more significant role than the instrument played.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov, NCT06618898, 27.09.2024.</p>","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"19"},"PeriodicalIF":2.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12143053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chlorine gas and ultrafine particle emissions from bleach disinfection: exposure risk characterization.","authors":"Luca Fontana, Luigi Fappiano, Luca Stabile, Antoine Chaillon, Giorgio Buonanno","doi":"10.1186/s12995-025-00465-6","DOIUrl":"10.1186/s12995-025-00465-6","url":null,"abstract":"<p><strong>Background: </strong>Chlorine-based disinfectants, such as bleach, are widely used in healthcare settings. However, their use has been linked to occupational respiratory risks. During disinfection, both chlorine gas and ultrafine particles (UFPs) can be generated, yet their exposure dynamics and health impacts remain poorly understood. This study aimed to characterize the emissions of chlorine gas and UFPs during disinfection under varying environmental and surface conditions to better understand exposure dynamics and inform risk mitigation strategies.</p><p><strong>Methods: </strong>Controlled experiments were conducted in a sealed chamber to simulate typical healthcare disinfection scenarios. Bleach was tested under different conditions of temperature, light exposure, and in the presence of organic contaminants, including simulated vomit, urine, and blood. Chlorine gas was quantified using electrochemical sensors, while UFP emissions were measured using a condensation particle counter and mobility particle sizers. Additional validation experiments were performed in real-world office settings before and after cleaning.</p><p><strong>Results: </strong>Chlorine gas was primarily emitted when bleach interacted with organic contaminants, particularly acidic substances such as simulated vomit, with an emission factor of 9.4 × 10⁶ µg/min/m². In contrast, UFP emissions were highest on clean surfaces under elevated temperature and light exposure, reaching up to 1.0 × 10¹¹ particles/min/m². Real-world validation confirmed that cleaning prior to disinfection significantly reduced chlorine gas emissions but led to increased UFP formation. Chlorine gas and UFP emissions were rarely observed simultaneously, indicating distinct and independent emission pathways.</p><p><strong>Conclusions: </strong>Bleach-based disinfection generates airborne hazards through separate mechanisms: chlorine gas via reactions with organic residues and UFPs through secondary processes influenced by environmental conditions. These findings support enhanced cleaning protocols, improved ventilation, and the need for regulatory attention to UFP exposure in occupational settings.</p>","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"18"},"PeriodicalIF":2.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SARS-CoV-2 infection risk by non-healthcare occupations: a systematic review and meta-analysis.","authors":"Katharina M A Gabriel, Christin Schröder, Rebecca Wolf, Ulrich Bolm-Audorff, Camilla Kienast, Joanna Smolinska, Gabriela Petereit-Haack, Andreas Seidler","doi":"10.1186/s12995-025-00462-9","DOIUrl":"10.1186/s12995-025-00462-9","url":null,"abstract":"<p><strong>Background: </strong>During the COVID-19 pandemic, several industries were deemed essential. However, information on infection risk in occupational settings outside of healthcare workers and medical staff (HCWs) remain scarce. Thus, a systematic review with meta-analysis was conducted to compile the risk of infection to SARS-CoV-2 in non-healthcare workers (non-HCWs).</p><p><strong>Methods: </strong>We screened three databases (EMBASE, PubMed, medRχiv) for studies on SARS-CoV-2 infection risk in working population. Several stages of severity (infection, hospitalisation, admission to intensive care unit (ICU), mortality) were eligible. Occupational specifications were harmonised according to the German classification of professions (KldB). All reported risk estimators were considered. Studies were analysed for their risk of bias. Results of random-effects meta-analyses were assessed for their evidence according to GRADE. Subgroup analyses were run for 'outcome', 'comparison group', and 'risk of bias'.</p><p><strong>Results: </strong>Of 9,081 publications identified, 25 were recognised as eligible, mainly describing the first year of the pandemic. For 20 occupations, we were able to carry out meta-analyses on KldB-4-level by integrating all stages of severity. Nine occupations were identified with a statistically significantly increased risk of infection for SARS-CoV-2, four of which had a relative risk (RR) of > 2: Occupations in meat processing (RR = 3.58 [95%-CI 1.46; 8.77]), occupations in building cleaning services (RR = 2.55 [95%-CI 1.51; 4.31]), occupations in cargo handling (RR = 2.52 [95%-CI 2.27; 2.79]) and cooks (RR = 2.53 [95%-CI 1.75; 3.67]). The certainty of evidence of eight results was found moderate or high.</p><p><strong>Conclusions: </strong>The first systematic review and meta-analysis of occupational SARS-CoV-2 infection risk in occupations other than HCWs revealed a considerably elevated risk in individual related services as well as in commercial services.</p><p><strong>Trial registration: </strong>PROSPERO CRD42021297572.</p>","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"17"},"PeriodicalIF":3.2,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Communication aspects of feedback from workers' health surveillance due to hand-arm vibration exposure - a scoping review.","authors":"Catarina Nordander, Mats Hagberg, Eirik Reierth, Tohr Nilsson","doi":"10.1186/s12995-025-00463-8","DOIUrl":"10.1186/s12995-025-00463-8","url":null,"abstract":"<p><strong>Background: </strong>The feedback of the surveillance results to the employee and the employer largely determines the impact of workers' health surveillance on workers' health and exposure. We are unaware of any guidebooks or articles on performing feedback on regulated workers' health surveillance, e.g., for vibration-exposed workers.</p><p><strong>Objectives: </strong>To identify existing knowledge of the communication aspects related to workers' health surveillance feedback in hand-arm vibration exposure, considering the perspectives of employees, employers, and groups.</p><p><strong>Eligibility criteria: </strong>We followed the extension for the Scoping Reviews (PRISMA-ScR) checklist. No time limits were set, so the databases were searched from their start (MEDLINE 1946 and EMBASE 1947) until the date of the full search (March 2024). Relevant information was extracted from 30 articles-none concerned hand-arm vibration but covered aspects of workers' health surveillance feedback.</p><p><strong>Sources of evidence: </strong>Two authors screened all abstracts in random pairs. They were blinded to each other's results. The third author resolved conflicts. Inclusion criteria were full-text articles, humans, workers' health surveillance, and aspects of communication reporting results to the employee, the workplace, or a health surveillance system. Altogether, 1914 abstracts were screened, and 84 full-text articles were assessed, of which 54 were excluded as they did not fulfill the criteria. The final publications selected included 30 articles published between 1980 and 2023; two blinded authors extracted relevant information in random pairs.</p><p><strong>Results: </strong>We found 16 of the included studies of longitudinal design, seven qualitative studies, four studies were cross-sectional, and three publications were reviews. The studies reported on workers' health surveillance that addressed musculoskeletal disorders and pain (n=8), risk of cardiovascular disorders (n=4) or hearing disorder (n=3), workability and fitness for duty (n=3), mental health (n=2), allergy/ asthma (n=2), and cancer (n=1). Additionally, seven studies addressed a mixture of disorders and general health (n=7).</p><p><strong>Conclusions: </strong>No publications addressed communication in workers' health surveillance due to hand-arm vibration exposure. However, we identified 30 studies addressing feedback from workers' health surveillance that were also relevant to workers' health surveillance due to hand-arm vibration exposure.</p>","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"16"},"PeriodicalIF":2.9,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effort-reward-imbalance, burnout, and physical pain mediate the relationship between overcommitment and depression in German Emergency Medical Technicians.","authors":"Laura Manns, Claus Vögele, Pascal Stammet, André Schulz","doi":"10.1186/s12995-025-00461-w","DOIUrl":"10.1186/s12995-025-00461-w","url":null,"abstract":"<p><strong>Background: </strong>Overcommitment (OC) is highly prevalent in health care employees, and may predict depression symptoms. The literature suggests that the relationship between OC and depression is mediated by Effort-Reward-Imbalance (ERI), burnout and physical pain. This study tested a two-step mediation effect between OC and depression by ERI in a first, and burnout and physical pain in a second step using a cohort of German Emergency Medical Technicians (EMTs).</p><p><strong>Methods: </strong>A cross-sectional study was carried out on a volunteer sample of 303 EMTs in Germany. OC and ERI were assessed using the ERI questionnaire, burnout with the Maslach Burnout Inventory, physical pain with the Short Form 36, and depression with the BDI-II. The relationship between these variables was tested using a mediation analysis.</p><p><strong>Results: </strong>We found a partial mediation effect between OC and depression via ERI, burnout (emotional exhaustion, personal accomplishment) and physical pain. The mediation effect of emotional exhaustion is significantly higher than those of depersonalization and physical pain.</p><p><strong>Conclusions: </strong>The partial mediation effect suggests the validity of our model assumptions, but also indicates direct relationships between variables (i.e. OC, ERI and depression). The identification of emotional exhaustion as key mediator implies that prevention and intervention approaches in EMTs should be based on this indicator.</p>","PeriodicalId":48903,"journal":{"name":"Journal of Occupational Medicine and Toxicology","volume":"20 1","pages":"15"},"PeriodicalIF":2.9,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}