Acta Clinica Belgica最新文献_第3页

Simvastatin-induced erythromelalgia: less is more. 辛伐他汀致红斑性肢痛症:少即是多。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2021-02-01 Epub Date: 2019-07-10 DOI: 10.1080/17843286.2019.1640929

Yuran Vanwonterghem, Samyah Shadid

引用次数: 3

Perceptions of physicians, medical and nursing students concerning shared decision-making: a cross-sectional study. 医生、医学和护理专业学生对共同决策的看法:一项横断面研究。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2021-02-01 Epub Date: 2019-07-04 DOI: 10.1080/17843286.2019.1637487

Gabriël Rafaël Cantaert, Ann Van Hecke, Kim Smolderen

{"title":"Perceptions of physicians, medical and nursing students concerning shared decision-making: a cross-sectional study.","authors":"Gabriël Rafaël Cantaert, Ann Van Hecke, Kim Smolderen","doi":"10.1080/17843286.2019.1637487","DOIUrl":"https://doi.org/10.1080/17843286.2019.1637487","url":null,"abstract":"Objective: The purpose of this study was to evaluate the attitudes of Flemish physicians and medical/nursing trainees regarding shared decision-making (SDM) and to determine possible differences based on sex, age, rank, occupation and specialty. Methods: A cross-sectional study was conducted between June and September 2017 in which the Patient-Practitioner Orientation Scale (PPOS) was translated and administered. Higher scores on the six-point scale indicate a patient-centered respondent. Independent t-tests, One and Two-way ANOVA and multivariate regression analysis with the variables sex, age, occupation and specialty were performed. Results: 266 responses from 93 physicians, 147 medical and 26 nursing students were analyzed. Mean sharing scores were 4,24 ± 0,64; 4,30 ± 0,61; and 4,30 ± 0,67, respectively. In the regression model, female sex (p < 0,10) and employment (p < 0,05) in general practice or internal medicine is predictive for higher sharing among physicians. Bivariate analysis revealed significant differences between specialisms (p < 0,05): pediatricians (4,79 ± 0,69), psychiatrists (4,74 ± 0,47), obstetricians/gynecologists (4,40 ± 0,38) and general practitioners (4,31 ± 0,59) scored higher on the PPOS than surgeons (3,84 ± 0,58). Conclusion: Flemish providers and trainees are disease-centered. Physicians' attitudes vary depending on their specialism, presumably due to prolonged exposure to the specific clinical context. Additionally, academic-trained nurses share the belief that the physician should decide and the patient should rely on his knowledge rather than his own. There is an urgent need for health policy and educational institutions to facilitate an environment in which SDM is supported.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"76 1","pages":"1-9"},"PeriodicalIF":1.6,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17843286.2019.1637487","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37116875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Echtyma gangrenosum caused by coinfection with group A Streptococcus and Staphylococcus aureus: an emerging etiology? Case reports and literature review. 由A群链球菌和金黄色葡萄球菌共同感染引起的坏疽斑:一种新的病因学?病例报告及文献回顾。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2021-02-01 Epub Date: 2019-06-18 DOI: 10.1080/17843286.2019.1630570

Antonio Ulpiano Trillig, Véronique Y Miendje Deyi, Pierre Youatou, Deborah Konopnicki

引用次数: 6

Mycobacterium abscessus felon complicated with osteomyelitis: not an ordinary nail salon visit. 重脓分枝杆菌合并骨髓炎:不是一个普通的美甲沙龙访问。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2020-12-01 Epub Date: 2019-06-28 DOI: 10.1080/17843286.2019.1637390

Jose Armando Gonzales Zamora, Abelardo Villar Astete

引用次数: 1

When clozapine appears at a dance event…. 当氯氮平出现在舞会上....

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2020-12-01 Epub Date: 2019-06-14 DOI: 10.1080/17843286.2019.1630068

Lisbeth Patteet, Kristof Maudens, Sarah Wille, Peter Blanckaert, Hugo Neels, Paul Calle

{"title":"When clozapine appears at a dance event….","authors":"Lisbeth Patteet, Kristof Maudens, Sarah Wille, Peter Blanckaert, Hugo Neels, Paul Calle","doi":"10.1080/17843286.2019.1630068","DOIUrl":"https://doi.org/10.1080/17843286.2019.1630068","url":null,"abstract":"Objectives: The content of substances sold and consumed as party drugs is often unknown. They may contain inactive, contaminated or unexpected ingredients, and the dosage of the active components may vary considerably. Obviously, these phenomena increase the chances of a wrong or delayed therapy. To illustrate this point, we report 3 cases of clozapine intoxication at a dance event where most likely clozapine tablets were sold as party drugs.Methods: The three cases were part of a prospective toxicology study at a nocturnal indoor dance event.Results: One patient had to be intubated after obstructive breathing with desaturation and bradycardia, while the 2 other patients presented with syncope and altered mental status. All patients recovered after 20 minutes to 8 hours. Systematic toxicological analysis of the blood samples revealed the presence of clozapine (73-244 ng/ml) and its metabolite norclozapine (9-59 ng/ml). A pill, found in a pocket of one patient, was identified as Leponex® 100 mg (clozapine). This neuroleptic drug is mainly prescribed for treatment-resistant schizophrenia. In clozapine-naive subjects, orthostatic hypotension, bradycardia and syncope have been reported with a single 25 mg oral dose. Serum clozapine concentrations of the 3 cases were below the defined therapeutic range (350-600ng/ml) and the clozapine:norclozapine ratios were suggestive for recent drug intake.Conclusion: Routine drug screening may be unable to detect the toxic agent(s) involved. Whenever unusual symptoms are observed in an intoxicated patient, blood and urine samples should be sent to a reference toxicology laboratory.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"75 6","pages":"416-420"},"PeriodicalIF":1.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17843286.2019.1630068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37055522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

A case report of successful eradication of new isolates of Burkholderia cenocepacia in a child with cystic fibrosis. 成功根除新分离的伯克霍尔德菌囊性纤维化儿童的病例报告。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2020-12-01 Epub Date: 2019-06-15 DOI: 10.1080/17843286.2019.1630585

V Sputael, G Van Schandevyl, L Hanssens

引用次数: 3

Application of the GheOP³S-tool in nursing home residents: acceptance and implementation of pharmacist recommendations. gheop3s工具在养老院居民中的应用:药师建议的接受与实施。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2020-12-01 Epub Date: 2019-06-26 DOI: 10.1080/17843286.2019.1634323

Katrien Foubert, Peter Muylaert, Els Mehuys, Annemie Somers, Mirko Petrovic, Koen Boussery

{"title":"Application of the GheOP3S-tool in nursing home residents: acceptance and implementation of pharmacist recommendations.","authors":"Katrien Foubert, Peter Muylaert, Els Mehuys, Annemie Somers, Mirko Petrovic, Koen Boussery","doi":"10.1080/17843286.2019.1634323","DOIUrl":"https://doi.org/10.1080/17843286.2019.1634323","url":null,"abstract":"ABSTRACT Background and objective: The prevalence of potentially inappropriate prescribing (PIP) among nursing home (NH) residents is high. This study aimed to investigate the acceptance and implementation of pharmacist recommendations based on a screening tool for PIP, the Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP3S)-tool. Setting and method: Prospective observational study in NH residents (≥ 70 years, using ≥ 5 medications) with a 3-month follow-up period. A pharmacist screened the medication lists using the GheOP3S-tool and formulated recommendations to reduce PIP. The acceptance of recommendations discussed during face-to-face pharmacist-general practitioner (GP) meetings was recorded. Implementation was examined by comparing baseline and follow-up medication lists. A pre-post comparison of the number of chronic medications and GheOP3S-criteria; the anticholinergic and sedative burden quantified by the Drug Burden Index (DBI); and medication costs was performed. Results: Screening with the GheOP3S-tool resulted in 168 pharmacist recommendations for 50 NH residents, mainly to stop (78.0%) and to substitute (14.3%) medications. Ninety-three % (156/168) of recommendations were considered relevant. GPs acceptance rate was 44.9%. Fifty-four % of all accepted recommendations were implemented. At follow-up, the number of chronic medications (p = 0.007), and DBI scores (p = 0.004) significantly differed from baseline. There was no significant decrease in the number of GheOP3S-criteria (p = 0.075) and medication costs (p > 0.05). Conclusion: The acceptance and implementation of pharmacist recommendations were relatively low. Future studies should increase the involvement of patients and all health-care providers. Interdisciplinary collaboration with sufficient education for all disciplines and patients is essential.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"75 6","pages":"388-396"},"PeriodicalIF":1.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17843286.2019.1634323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37363440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Necrotizing myositis case report and brief literature study. 坏死性肌炎1例报告及简要文献研究。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2020-12-01 Epub Date: 2019-07-03 DOI: 10.1080/17843286.2019.1637388

Arthur Basso, Filip Moerman, Christophe Ronsmans, Martine Demarche

引用次数: 1

Survival prediction in patients with cutaneous melanoma by tumour lymphangiogenesis. 通过肿瘤淋巴管生成预测皮肤黑色素瘤患者的生存。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2020-12-01 Epub Date: 2019-06-18 DOI: 10.1080/17843286.2019.1629076

Zorica Špirić, Milka Vještica, Mirela Erić

{"title":"Survival prediction in patients with cutaneous melanoma by tumour lymphangiogenesis.","authors":"Zorica Špirić, Milka Vještica, Mirela Erić","doi":"10.1080/17843286.2019.1629076","DOIUrl":"https://doi.org/10.1080/17843286.2019.1629076","url":null,"abstract":"Objectives: Melanoma induces lymphangiogenesis by secreting lymphangiogenic growth factors. The aim of this study was to examine the role of tumour lymphangiogenesis in survival of patients with cutaneous melanoma. Methods: Immunostaining of one hundred melanoma specimens was done with lymphatic-specific antibody D2-40. The quantification of tumour lymphangiogenesis - lymphatic vessel density (LVD) and lymphatic vessel area (LVA) - was calculated by computer-assisted morphometric analysis. Results: High intratumoural LVD, high peritumoural LVD, male gender, greater tumour thickness and Clark level IV/V were significantly associated with shorter disease-free survival (p= 0.001, p= 0.004, p= 0.004, p= 0.000 and p= 0.008, respectively) and melanoma-specific survival (p= 0.002, p= 0.002, p= 0.001, p= 0.000 and p= 0.017, respectively), while the trunk melanoma site was significantly associated only with shorter disease-free survival (p= 0.033). No significant association of LVA with survival was found. At multivariate analysis, peritumoural LVD [hazard ratio (HR) = 2.143, 95% confidence interval (CI) 1.097-4.189, p= 0.026)] and melanoma thickness (HR = 1.276, 95%CI 1.106-1.473, p= 0.001) were independent predictors of disease-free survival, while intratumoural LVD (HR = 3.446, 95%CI 1.465-8.109, p= 0.005), peritumoural LVD (HR = 2.742, 95%CI 1.313-5.725, p= 0.007) and gender (HR = 2.880, 95%CI 1.304-6.362, p= 0.009) were independent predictors of melanoma-specific survival. Conclusion: Тhis study shows that LVD enables better prediction of survival than melanoma thickness and other clinical-pathological parameters. Intratumoural LVD is the most significant predictor of melanoma-specific survival, while only peritumoural LVD has a significant impact on both, a disease-free survival and a melanoma-specific survival.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"75 6","pages":"379-387"},"PeriodicalIF":1.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17843286.2019.1629076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37065106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Dyspnea in homosexual male patients: throwback to an occasionally forgotten but severe clinical presentation of HIV/AIDS. 男同性恋患者的呼吸困难:倒退到偶尔被遗忘但严重的HIV/AIDS临床表现。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2020-12-01 Epub Date: 2019-05-25 DOI: 10.1080/17843286.2019.1622880

Koen Verbeke, Roel Verbuyst, Christiane Brands, Hans Slabbynck

{"title":"Dyspnea in homosexual male patients: throwback to an occasionally forgotten but severe clinical presentation of HIV/AIDS.","authors":"Koen Verbeke, Roel Verbuyst, Christiane Brands, Hans Slabbynck","doi":"10.1080/17843286.2019.1622880","DOIUrl":"https://doi.org/10.1080/17843286.2019.1622880","url":null,"abstract":"Pneumocystis jirovecii pneumonia (PJP) can be a severe indicator disease of acquired immunodeficiency syndrome (AIDS). We present two cases of homosexual male patients who came to the emergency unit of a Belgian hospital because of shortness of breath. Both men had been sent back home, initially diagnosed with a benign viral infection. Because of worsening symptoms and gradually evolving hypoxemia, both patients came back and were admitted to the hospital with a diagnosis of (microbiology proven) Pneumocystis jirovecii pneumonia. HIV serology in both men was tested and was clearly positive, indicating a new diagnosis of HIV infection. In this article, we provide an overview of this possibly severe AIDS defining condition. First, we give an introduction of the history of HIV/AIDS and its occurrence in homosexual males in Europe. Secondly, we provide an overview of the diagnosis and treatment of Pneumocystis jirovecii pneumonia. Finally, since the first case reports of Pneumocystis jirovecii pneumonia at the beginning of the AIDS epidemic also included homosexual men, we emphasize the potential importance of a sexual anamnesis in young male patients with an initial complaint of dyspnea.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"75 6","pages":"411-415"},"PeriodicalIF":1.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17843286.2019.1622880","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37273919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0