Lancet Global Health最新文献

{"title":"Mpox vaccination strategies in DR Congo.","authors":"Rajesh Kanna Gopal, Pitchaipillai Sankar Ganesh, Naji Naseef Pathoor","doi":"10.1016/S2214-109X(25)00006-3","DOIUrl":"https://doi.org/10.1016/S2214-109X(25)00006-3","url":null,"abstract":"","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":"13 3","pages":"e415"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tuberculosis and people who use drugs: why focus on this overlooked population is important and why adapted interventions are necessary.","authors":"Morgana D'Ottavi, Peter Godfrey-Faussett, Corinne S Merle, Mircea T Sofonea, Didier Laureillard, Peter Vickerman, Jean-Pierre Molès, Frederick L Altice, Philippe Van de Perre, Jack Stone, Nicolas Nagot","doi":"10.1016/S2214-109X(24)00481-9","DOIUrl":"10.1016/S2214-109X(24)00481-9","url":null,"abstract":"<p><p>People who use drugs show a higher incidence and prevalence of tuberculosis than people who do not use drugs in areas where Mycobacterium tuberculosis is endemic. However, this population is largely neglected in national tuberculosis programmes. Strategies for active case finding, screening, and linkage to care designed for the general population are not adapted to the needs of people who use drugs, who are stigmatised and difficult to reach. Moreover, access to care, linkage to care, and treatment adherence are challenging for such a marginalised population. Learning from the HIV field about successful interventions targeting this group, we advocate for the implementation of tuberculosis interventions adapted for people who use drugs, highlighting the key role that community-based approaches could have in both design and implementation. Alongside reducing health inequities by reducing the excess tuberculosis burden among people who use drugs, these targeted interventions can also reduce tuberculosis transmission at the population level.</p>","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":" ","pages":"e593-e598"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Childhood iron-folic acid supplementation in India for mild-to-moderate anaemia.","authors":"Tinku Thomas, Anura Kurpad","doi":"10.1016/S2214-109X(25)00053-1","DOIUrl":"https://doi.org/10.1016/S2214-109X(25)00053-1","url":null,"abstract":"","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":"13 3","pages":"e383-e384"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The paradox of increasing serious health-related suffering.","authors":"Camilla Zimmermann","doi":"10.1016/S2214-109X(24)00530-8","DOIUrl":"https://doi.org/10.1016/S2214-109X(24)00530-8","url":null,"abstract":"","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":"13 3","pages":"e373-e374"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishing the value of regional cooperation and a critical role for regional organisations in managing future health emergencies.","authors":"Afifah Rahman-Shepherd, Nelson Aghogho Evaborhene, Ayelet Berman, Ana B Amaya, Ezekiel Boro, Osman Dar, Zheng Jie Marc Ho, Anne-Sophie Jung, Mishal Khan, Olaa Mohamed-Ahmed, Oyeronke Oyebanji, Tikki Elka Pangestu, Sabina Faiz Rashid, Ahmed Razavi, Pía Riggirozzi, Helena Legido-Quigley, Li Yang Hsu","doi":"10.1016/S2214-109X(24)00500-X","DOIUrl":"https://doi.org/10.1016/S2214-109X(24)00500-X","url":null,"abstract":"<p><p>The COVID-19 pandemic revealed the failures of global, multilateral cooperation to respond and adapt to health emergencies while observing the principles of solidarity and equity. This response has raised the question of whether the global architecture for health emergencies is fit for purpose. In this Health Policy, amid proposals to reform this architecture, we consider the potential value of regional cooperation and the role regional organisations might play in delivering effective and equitable solutions to the challenges posed by public health emergencies. Drawing on our multidisciplinary perspectives and diverse experience of geographical regions, we explore the value of regional cooperation, the role of regional organisations, where they could have the greatest impact, and the major factors affecting regional cooperation and regional organisations in managing public health emergencies. As the COVID-19 pandemic reshapes our approach to health emergencies, leveraging and integrating the capabilities of regional organisations will be crucial for improving preparedness and response efforts globally.</p>","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":"13 3","pages":"e585-e592"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging observational and experimental evidence to eradicate poverty: lessons from the Bolsa Familia Program.","authors":"Leandro F M Rezende, Jacqueline Wahrhaftig","doi":"10.1016/S2214-109X(25)00008-7","DOIUrl":"https://doi.org/10.1016/S2214-109X(25)00008-7","url":null,"abstract":"","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":"13 3","pages":"e385-e386"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal exposure to HIV pre-exposure prophylaxis and birth, growth, and social-emotional developmental outcomes throughout early childhood in Kenya: a prospective cohort study.","authors":"Laurén Gómez, John Kinuthia, Felix Abuna, Jared M Baeten, Julia Dettinger, Anna Larsen, Mary Marwa, Nancy Ngumbau, Ben Odhiambo, Pascal Omondi, Joshua Stern, Barbra A Richardson, Salphine Watoyi, Grace John-Stewart, Jillian Pintye","doi":"10.1016/S2214-109X(24)00471-6","DOIUrl":"10.1016/S2214-109X(24)00471-6","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;As pre-exposure prophylaxis (PrEP) implementation continues to scale up among pregnant people, accruing safety data following prenatal PrEP exposure remains important. In this study, we aimed to evaluate the relationship between prenatal PrEP exposure and birth and infant or child outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This prospective cohort study analysed data from the PrEP Implementation for Mothers in Antenatal Care study (NCT03070600). Participants were eligible for inclusion if they were currently pregnant, not currently using PrEP, were aged 15 years or older, planned to remain in the study area, were not enrolled in other studies, and did not have HIV or tuberculosis. Participants enrolled during pregnancy at 20 maternal and child health clinics in western Kenya and were followed up until 9 months postpartum. Those who reported taking PrEP at any antenatal visits were identified as prenatally PrEP exposed. In an extension cohort, participants and their children were followed up until 36 months postpartum. Infant anthropometry and social-emotional development using the Ages and Stages Questionnaire (ASQ-SE), second edition were assessed by trained study nurses. Among a subset of participants, we confirmed prenatal PrEP exposure using tenofovir diphosphate concentrations in dried blood spots. Perinatal outcomes (birth, growth, and neurodevelopment) were the primary outcomes assessed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Findings: &lt;/strong&gt;Between Jan 15, 2018, and Jul 31, 2019, 4063 female individuals were enrolled and included in the analysis, of whom 558 (13·7%) used PrEP during pregnancy, initiating at a median of 26 weeks' gestation (IQR 22-31) for a median duration of 9·6 weeks in pregnancy (5·7-15·0). Compared with PrEP-unexposed pregnancies, there was no difference in pregnancy loss (ie, miscarriage), stillbirth, preterm birth, or neonatal death among PrEP exposed pregnancies (all p&gt;0·05). There were no differences in infant length or weight at 6 weeks, 6 months, and 9 months (all p&gt;0·05) between children with and without prenatal PrEP exposure, including underweight, stunting, and wasting. Results were similar when analysed separately by trimester of PrEP initiation and duration on PrEP, and in a subset at 24 months, 30 months, and 36 months. Prenatal PrEP exposure was not associated with ASQ-SE scores at 24-months (p=0·12), 30-months (p=0·75), or 36-months (p=0·81). No differences in adverse perinatal and infant outcomes were found among Kenyan individuals with quantifiable prenatal tenofovir diphosphate exposure.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Interpretation: &lt;/strong&gt;We found no significant differences in adverse birth or infant or child outcomes for 3 years of follow-up by prenatal PrEP exposure status. These data support findings from previous studies that demonstrate the safety of oral PrEP use during pregnancy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Funding: &lt;/strong&gt;The National Institutes of Health, National Institute of Allergy and Infectious Disease; ","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":"13 3","pages":"e467-e478"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinguishing between mortality rates for heart failure with preserved versus reduced ejection fraction - Authors' reply.","authors":"Jiefu Yang, Hua Wang","doi":"10.1016/S2214-109X(25)00017-8","DOIUrl":"https://doi.org/10.1016/S2214-109X(25)00017-8","url":null,"abstract":"","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":"13 3","pages":"e419-e420"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Realising the benefits of oxygen through essential emergency and critical care.","authors":"Tim Baker, Karima Khalid, Alhassan Datti Mohammed, Alexa Wharton-Smith, Ganbold Lundeg, Rob Mitchell, Andrew Argent, Pauline F Convocar, Carl Otto Schell","doi":"10.1016/S2214-109X(24)00482-0","DOIUrl":"10.1016/S2214-109X(24)00482-0","url":null,"abstract":"","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":" ","pages":"e387-e388"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The crucial role of industry in increasing access to medical oxygen.","authors":"Jayasree K Iyer, Emma Cahuzac, Zachary Katz, Kaodili Udeh, Noha El-Ghobashy, David Lowrance, Kristoffer Gandrup-Marino, Robert Matiru","doi":"10.1016/S2214-109X(24)00556-4","DOIUrl":"10.1016/S2214-109X(24)00556-4","url":null,"abstract":"","PeriodicalId":48783,"journal":{"name":"Lancet Global Health","volume":" ","pages":"e389-e391"},"PeriodicalIF":19.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}