Rami El Ojaimi , Gaëlle Cheisson , Emmanuel Cosson , Carole Ichai , Sophie Jacqueminet , Bogdan Nicolescu-Catargi , Alexandre Ouattara , Igor Tauveron , Paul Valensi , Dan Benhamou
{"title":"Recent advances in perioperative care of patients using new antihyperglycaemic drugs and devices dedicated to diabetes","authors":"Rami El Ojaimi , Gaëlle Cheisson , Emmanuel Cosson , Carole Ichai , Sophie Jacqueminet , Bogdan Nicolescu-Catargi , Alexandre Ouattara , Igor Tauveron , Paul Valensi , Dan Benhamou","doi":"10.1016/j.accpm.2024.101468","DOIUrl":"10.1016/j.accpm.2024.101468","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 1","pages":"Article 101468"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chin Wen Tan , D.G.P. Luther , Hon Sen Tan , Nabilah Rahman , Mihir Gandhi , Rehena Sultana , Alex Tiong Heng Sia , Ban Leong Sng
{"title":"The association between neuraxial labor analgesia and subacute pain after childbirth: A randomized controlled trial","authors":"Chin Wen Tan , D.G.P. Luther , Hon Sen Tan , Nabilah Rahman , Mihir Gandhi , Rehena Sultana , Alex Tiong Heng Sia , Ban Leong Sng","doi":"10.1016/j.accpm.2024.101450","DOIUrl":"10.1016/j.accpm.2024.101450","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 1","pages":"Article 101450"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A French regional survey of the role of general practitioners in the follow-up of patients with post-intensive-care syndrome (PICS)","authors":"N. Elhadjene , A. Crouzet, R. Charles, J. Morel","doi":"10.1016/j.accpm.2024.101466","DOIUrl":"10.1016/j.accpm.2024.101466","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 1","pages":"Article 101466"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enric Barbeta , Carlos Ferrando , Rubén López-Aladid , Anna Motos , Letícia Bueno-Freire , Laia Fernández-Barat , Alba Soler-Comas , Andrea Palomeque , Albert Gabarrús , Antonio Artigas , Marta Camprubí-Rimblas , Gianluigi Li Bassi , Teresa López-Sobrino , Elena Sandoval , David Toapanta , Sara Fernández , Ricard Mellado-Artigas , Luigi Zattera , Jordi Vallverdú , John G. Laffey , Antoni Torres
{"title":"Association between driving pressure, systemic inflammation and non-pulmonary organ dysfunction in patients with acute respiratory distress syndrome, a prospective pathophysiological study","authors":"Enric Barbeta , Carlos Ferrando , Rubén López-Aladid , Anna Motos , Letícia Bueno-Freire , Laia Fernández-Barat , Alba Soler-Comas , Andrea Palomeque , Albert Gabarrús , Antonio Artigas , Marta Camprubí-Rimblas , Gianluigi Li Bassi , Teresa López-Sobrino , Elena Sandoval , David Toapanta , Sara Fernández , Ricard Mellado-Artigas , Luigi Zattera , Jordi Vallverdú , John G. Laffey , Antoni Torres","doi":"10.1016/j.accpm.2024.101458","DOIUrl":"10.1016/j.accpm.2024.101458","url":null,"abstract":"<div><h3>Background</h3><div>Driving pressure is thought to determine the effect of low tidal ventilation on survival in patients with acute respiratory distress syndrome. The leading cause of mortality in these patients is non-pulmonary multiorgan dysfunction, which is believed to worsen due to the biological response to mechanical ventilation (biotrauma). Therefore, we aimed to analyze the association between driving pressure, biotrauma, and non-pulmonary multiorgan dysfunction. Additionally, we analyzed this relationship for tidal volume/predicted body weight.</div></div><div><h3>Methods</h3><div>Observational study that included adult patients with acute respiratory distress syndrome undergoing invasive mechanical ventilation admitted to the Hospital Clinic of Barcelona, Spain, between June 2019 and February 2021. We conducted mixed-effects models to assess the effects of driving pressure and tidal volume/predicted body weight on the evolution of 22 log-transformed biomarker variables during the first, third, and fifth days after study enrollment. These 22 systemic biomarkers characterized epithelial and endothelial pulmonary dysfunction, inflammation, and coagulation disorders in the included patients. In the same fashion, the association between driving pressure and non-pulmonary multiorgan dysfunction was evaluated by the non-pulmonary sequential organ failure assessment score (non-pulmonary SOFA) and its associated variables. Finally, we performed mediation analyses to assess whether the relationship between biomarkers and driving pressure was mediated by other ventilator-induced lung injury parameters.</div></div><div><h3>Results</h3><div>Thirty-eight patients were included. Driving pressure was independently associated with soluble Receptor for advanced glycation end-products, Interleukin (IL)-8, IL-6, IL-10, IL-17, Interferon-ɣ, Chemokine (C-C motif)-2, Vascular endothelial growth factor, Tissue factor, Protein C, Protein S, and higher dose of norepinephrine. However, this relationship attenuated over time. In contrast, tidal volume/predicted body weight was not associated with any of the 22 biomarkers tested . A concomitant increase in positive end-inspiratory plateau pressure or tidal volume did not mediate the effect of driving pressure on biomarkers. Conversely, the association between compliance of the respiratory system and pulmonary epithelial dysfunction was primarily mediated by driving pressure.</div></div><div><h3>Conclusions</h3><div>Driving pressure, but not tidal volume/predicted body weight, was correlated with epithelial and endothelial pulmonary dysfunction, inflammation, coagulation disorders, and hemodynamic dysfunction. However, this relationship diminished over time.</div></div>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 1","pages":"Article 101458"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emmanuel Dudoignon , Julia Schneider, Francois Caméléna , Christian de Tymowski , François Dépret
{"title":"Microbiological monitoring during antibiotic therapy in patients with ventilated acquired pneumonia: A proof-of-concept","authors":"Emmanuel Dudoignon , Julia Schneider, Francois Caméléna , Christian de Tymowski , François Dépret","doi":"10.1016/j.accpm.2024.101454","DOIUrl":"10.1016/j.accpm.2024.101454","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 1","pages":"Article 101454"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Protective Role of Specialized Supraglottic Airway Devices in Gastrointestinal Endoscopy","authors":"André Van Zundert , Paul Zilberman , Dan Benhamou","doi":"10.1016/j.accpm.2024.101459","DOIUrl":"10.1016/j.accpm.2024.101459","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 1","pages":"Article 101459"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guillaume Mortamet , Christophe Milési , Michael Levy
{"title":"Significance of ongoing enhancement of Pediatric Intensive Care Unit follow-up. Authors’ reply","authors":"Guillaume Mortamet , Christophe Milési , Michael Levy","doi":"10.1016/j.accpm.2024.101465","DOIUrl":"10.1016/j.accpm.2024.101465","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 1","pages":"Article 101465"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mikhael Giabicani , Emmanuel Weiss , Frédérique Claudot , Gérard Audibert , Scarlett-May Ferrié , Pierre-François Perrigault , Ellen M. Robinson , Mildred Z. Solomon , Marta Spranzi , Marie-France Mamzer
{"title":"Intractable conflicts over end-of-life decisions: A descriptive and ethical analysis of French case-law","authors":"Mikhael Giabicani , Emmanuel Weiss , Frédérique Claudot , Gérard Audibert , Scarlett-May Ferrié , Pierre-François Perrigault , Ellen M. Robinson , Mildred Z. Solomon , Marta Spranzi , Marie-France Mamzer","doi":"10.1016/j.accpm.2024.101463","DOIUrl":"10.1016/j.accpm.2024.101463","url":null,"abstract":"<div><h3>Context</h3><div>In European and Anglo-Saxon countries, life-sustaining treatment (LST) limitation decisions precede more than 80% of ICU deaths. However, there is now increasing evidence of disagreement and conflict between clinical teams and family members over LST limitation decisions. In some cases, these conflicts are brought to the courts. The aim of this study was to provide a descriptive and qualitative analysis of cases brought to the French courts.</div></div><div><h3>Methods</h3><div>We conducted a retrospective national observational study. All identified cases of emergency recourse to the judge in the context of LST limitation decisions in France between 2005 and 2022 were included.</div></div><div><h3>Results</h3><div>Seventy-six cases were investigated by the judge, with an increasing number over the years. The LST limitation decisions contested by the relatives were mainly decisions to withdraw treatment (78%) concerning patients with neurological injury (76%). The judge successively assessed the compliance with the legal decision-making process and the characterization of the inappropriateness of treatments. The latter was assessed by the judge using medical and non-medical criteria. In all, the medical decision was upheld in 29 cases (38%) and over-ruled in 20 cases (26%). Thirteen cases (17%) were finally settled out of court, and 14 patients (18%) died before the end of the investigation. The qualitative analysis highlighted opposing moral values and principles put forward by family members and physicians.</div></div><div><h3>Conclusion</h3><div>The growing incidence and deeply intertwined elements of these conflicts call for more policy and research to resolve them before they go to court.</div></div>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 1","pages":"Article 101463"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}