Clinics in Colon and Rectal Surgery最新文献_第9页

Informed Consent and Shared Decision Making in the Perioperative Environment. 围术期环境中的知情同意和共同决策。

IF 1.4 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-28 eCollection Date: 2023-05-01 DOI: 10.1055/s-0043-1761158

Elizabeth D Krebs, Sook C Hoang

引用次数: 0

Perioperative Nutritional Considerations in Colon and Rectal Surgery. 结肠和直肠手术围手术期营养注意事项。

IF 1.4 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-25 eCollection Date: 2023-05-01 DOI: 10.1055/s-0043-1761152

Thomas Curran

{"title":"Perioperative Nutritional Considerations in Colon and Rectal Surgery.","authors":"Thomas Curran","doi":"10.1055/s-0043-1761152","DOIUrl":"10.1055/s-0043-1761152","url":null,"abstract":"Malnutrition is common in surgical patients and is associated with substantially increased morbidity and mortality. Dedicated assessment of nutritional status is advised by major nutrition and surgical societies. Assessment may utilize comprehensive and validated nutritional assessment tools or targeted history, physical examination with accompanying serologic markers to identify nutritional risk preoperatively. Emergent surgery in malnourished patients should proceed as the clinical situation dictates with consideration of ostomy or primary anastomosis with proximal fecal diversion to mitigate postoperative infectious complications. Nonemergent surgery should be delayed to facilitate nutritional optimization via oral nutritional supplementation preferably and total parenteral nutrition if necessary for at least 7 to 14 days. Exclusive enteral nutrition may be considered to optimize nutritional status and inflammation in patients with Crohn's disease. Immunonutrition use in the preoperative setting is not supported by evidence. Perioperative and postoperative immunonutrition may be of benefit but requires dedicated study in the contemporary era. Close attention to preoperative nutritional status and optimization represents a critical opportunity to improve outcomes in patients undergoing colorectal surgery.","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"36 3","pages":"192-197"},"PeriodicalIF":1.4,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9421194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Bacteria in the Development of Colorectal Cancer. 细菌在大肠癌发病中的作用。

IF 1.4 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-25 eCollection Date: 2023-03-01 DOI: 10.1055/s-0042-1760679

Ryan M Thomas

{"title":"Role of Bacteria in the Development of Colorectal Cancer.","authors":"Ryan M Thomas","doi":"10.1055/s-0042-1760679","DOIUrl":"10.1055/s-0042-1760679","url":null,"abstract":"Colorectal cancer (CRC) is the second leading cause of cancer-related death in the United States. Once limited to older populations, the incidence of CRC in patients under the age of 50 years is increasing and the etiology for this is uncertain. One hypothesis lies on the impact of the intestinal microbiome. The intestinal microbiome, composed primarily of bacteria but also viruses, fungi, and archaea, has been shown to regulate CRC development and progression both in vitro and in vivo. In this review, the role and intersection of the bacterial microbiome in various stages of clinical CRC development and management are discussed beginning with CRC screening. Various mechanisms whereby the microbiome has been shown to modulate CRC development including the influence of diet on the microbiome, bacterial-induced injury to the colonic epithelium, bacterial-produced toxins, and alteration of normal cancer immunosurveillance by the microbiome are discussed. Finally, the influence of microbiome on the response of CRC to treatment is discussed while highlighting ongoing clinical trials. The complexities of the microbiome and its role in CRC development and progression have become apparent and will require ongoing commitment to translate laboratory findings into meaningful clinical results that will aid more than 150,000 patients that develop CRC every year.","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"36 2","pages":"105-111"},"PeriodicalIF":1.4,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10850287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacterial Decontamination: Bowel Preparation and Chlorhexidine Bathing. 细菌净化：肠道准备和洗必泰洗浴。

IF 1.2 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-25 eCollection Date: 2023-05-01 DOI: 10.1055/s-0043-1761154

Yadin Bornstein, Elizabeth C Wick

引用次数: 0

Traci L. Hedrick, MD, MSc, FACS, FASCRS. Traci L. Hedrick, MD, MSc, FACS, FASCRS.

IF 1.4 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-25 eCollection Date: 2023-05-01 DOI: 10.1055/s-0043-1760866

Scott R Steele

引用次数: 0

Microbiome. 微生物组。

IF 1.4 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-25 eCollection Date: 2023-03-01 DOI: 10.1055/s-0042-1760677

Benjamin D Shogan

引用次数: 0

A Brief History of Microbial Study and Techniques for Exploring the Gastrointestinal Microbiome. 微生物研究简史和探索胃肠道微生物组的技术。

IF 1.2 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-25 eCollection Date: 2023-03-01 DOI: 10.1055/s-0042-1760678

Ashley M Sidebottom

{"title":"A Brief History of Microbial Study and Techniques for Exploring the Gastrointestinal Microbiome.","authors":"Ashley M Sidebottom","doi":"10.1055/s-0042-1760678","DOIUrl":"10.1055/s-0042-1760678","url":null,"abstract":"Over the past 20 years, the study of microbial communities has benefited from simultaneous advancements across several fields resulting in a high-resolution view of human consortia. Although the first bacterium was described in the mid-1600s, the interest in community membership and function has not been a focus or feasible until recent decades. With strategies such as shotgun sequencing, microbes can be taxonomically profiled without culturing and their unique variants defined and compared across phenotypes. Approaches such as metatranscriptomics, metaproteomics, and metabolomics can define the current functional state of a population through the identification of bioactive compounds and significant pathways. Prior to sample collection in microbiome-based studies it is critical to evaluate the requirements of downstream analyses to ensure accurate processing and storage for generation of high data quality. A common pipeline for the analysis of human samples includes approval of collection protocols and method finalization, patient sample collection, sample processing, data analysis, and visualization. Human-based microbiome studies are inherently challenging but with the application of complementary multi-omic strategies there is an unbounded potential for discovery.","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"36 2","pages":"98-104"},"PeriodicalIF":1.2,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9340882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Influence of the Microbiome on Metastatic Colorectal Cancer. 微生物组对转移性结直肠癌的影响

IF 1.2 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-25 eCollection Date: 2023-03-01 DOI: 10.1055/s-0043-1760864

Samuel Cass, Michael G White

{"title":"The Influence of the Microbiome on Metastatic Colorectal Cancer.","authors":"Samuel Cass, Michael G White","doi":"10.1055/s-0043-1760864","DOIUrl":"10.1055/s-0043-1760864","url":null,"abstract":"The microbiome (bacteria, viruses, and fungi) that exist within a patient's gastrointestinal tract and throughout their body have been increasingly understood to play a critical role in a variety of disease, including a number of cancer histologies. These microbial colonies are reflective of a patient's overall health state, their exposome, and germline genetics. In the case of colorectal adenocarcinoma, significant progress has been made in understanding the mechanism the microbiome plays beyond mere associations in both disease initiation and progression. Importantly, this improved understanding holds the potential to further identify the role these microbes play in colorectal cancer. We hope this improved understanding will be able to be leveraged in the future through either biomarkers or next-generation therapeutics to augment contemporary treatment algorithms through the manipulation of a patient's microbiome-whether through diet, antibiotics, prebiotics, or novel therapeutics. Here we review the role of the microbiome in the setting of patients with stage IV colorectal adenocarcinoma in both the development and progression or disease as well as response to therapeutics.","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"36 2","pages":"112-119"},"PeriodicalIF":1.2,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10793194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative Identification and Management of Anemia in the Colorectal Surgery Patient. 结直肠手术患者术前贫血的识别与管理。

IF 1.4 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-25 eCollection Date: 2023-05-01 DOI: 10.1055/s-0043-1760868

Kevin T Lynch, Taryn E Hassinger

{"title":"Preoperative Identification and Management of Anemia in the Colorectal Surgery Patient.","authors":"Kevin T Lynch, Taryn E Hassinger","doi":"10.1055/s-0043-1760868","DOIUrl":"10.1055/s-0043-1760868","url":null,"abstract":"Preoperative anemia is a common finding in patients undergoing colorectal surgery, particularly those with cancer. While often multifactorial, iron deficiency anemia remains the most common cause of anemia in this patient population. Although seemingly innocuous, preoperative anemia is associated with an increased risk of perioperative complications and need for allogenic blood transfusions, both of which may worsen cancer-specific survival. Preoperative correction of anemia and iron deficiency is thus necessary to diminish these risks. Current literature supports preoperative screening for anemia and iron deficiency in patients slated to undergo colorectal surgery for malignancy or for benign conditions with associated patient- or procedure-related risk factors. Accepted treatment regimens include iron supplementation-either oral or intravenous-as well as erythropoietin therapy. Autologous blood transfusion should not be utilized as a treatment for preoperative anemia when there is time to implement other corrective strategies. Additional study is still needed to better standardize preoperative screening and optimize treatment regimens.","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"36 3","pages":"161-166"},"PeriodicalIF":1.4,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9421192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fecal Microbiota Transplantation. 粪便微生物群移植。

IF 1.4 4区医学

Clinics in Colon and Rectal Surgery Pub Date : 2023-01-25 eCollection Date: 2023-03-01 DOI: 10.1055/s-0043-1760865

Yao-Wen Cheng, Monika Fischer

引用次数: 0