Joel Brind, Steven J Condly, Angela Lanfranchi, Brent Rooney
{"title":"Induced abortion as an independent risk factor for breast cancer: a systematic review and meta-analysis of studies on south asian women.","authors":"Joel Brind, Steven J Condly, Angela Lanfranchi, Brent Rooney","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>South Asia, a historically low-incidence region for breast cancer, has produced many recent studies examining reproductive factors. We compiled these studies to confirm the reality of the significant association reported in the first, 1996 review of induced abortion as a risk factor, independent of abortion's known effect in abrogating the protection afforded by full-term pregnancy.</p><p><strong>Methods: </strong>We searched the medical literature for English language studies on breast cancer incidence in women in South Asia published from 1 January, 2000 through 30 June, 2017, using Pubmed, Scholar-Google, and bibliographic searches. Studies were included which reported overall data on induced abortion and/or abortion non-specifically. All 20 eligible studies were of retrospective, case-control design. Data from individual studies were combined using random effects modeling, following the determination of significant heterogeneity.</p><p><strong>Results: </strong>Cumulative OR for all 20 studies was 2.51 (95%CI: 1.67-3.75) and 3.91 (95%CI: 1.02-14.97) for the five studies which reported specific data on induced abortion. Significant dose-dependence was observed among all 5 studies which stratified by number of abortions. Meta-regression of OR v. abortion prevalence among controls was statistically significant, as observed in a 2013 meta-analysis in China.</p><p><strong>Conclusion: </strong>The moderately strong association identified between abortion and breast cancer explains in part the spread of the breast cancer epidemic to South Asia as it has become Westernized. Continuing denial of the abortion-breast cancer association can only ensure that the acknowledged worldwide breast cancer epidemic will continue to worsen, costing many millions of women their lives over the next several decades.</p>","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"33 1","pages":"32-54"},"PeriodicalIF":0.9,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37021676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surrogacy, the handmaid's tale, and reproductive ethics.","authors":"Jennifer Lahl","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 2","pages":"241-244"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35579497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Healthcare and Planned Parenthood: the significance for pro-life OB/GYNs.","authors":"Jeffrey J Pauls, Carl Landwehr","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 2","pages":"315-324"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35580415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for the Adolescent Woman and Her Parents: Abortion and the Risk of Breast Cancer.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Studies from many nations suggest that induced abortion (IA) may be a causal risk factor for the development of breast cancer. Researchers agree that IA contributes to the increased risk of breast cancer by delaying the timing of a full-term pregnancy which is a protective factor. Increasing numbers of studies now show that IA prior to 32 weeks in and of itself is a risk factor for breast cancer due to the physiology of breast development and the manner in which abortion interferes with the maturation of the breast cells. Although largely ignored by the mainstream medical community, this risk information deserves a prominent place in the education of all adolescent women who may, in the future, consider an IA.</p>","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 1","pages":"99-104"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35580426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The abortion agenda in Africa.","authors":"Obianuju Ekeocha","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 2","pages":"265-268"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35579500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The menstrual cycle as a vital sign: the use of naprotechnology.","authors":"Shirley Gonzáles","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 2","pages":"277-286"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35580412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abortion's Impact on Prematurity: Closing the Knowledge Gap.","authors":"Martin J McCaffrey","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 1","pages":"43-52"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35580423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Grief, bereavement, and traumatic stress as natural results of reproductive losses.","authors":"Naji Abi-Hashem","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 2","pages":"245-254"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35579498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Burden of Abortion and the Preterm Birth Crisis.","authors":"Martin J McCaffrey","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 1","pages":"73-98"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35580425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Declaration and Expert Report.","authors":"Jerry M Obritsch","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 1","pages":"113-123"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35580428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}