Issues in Law & Medicine最新文献_第10页

Fetal Therapy for Down Syndrome: Report of Three Cases and a Review of the Literature. 胎儿治疗唐氏综合征:三例报告及文献复习。

IF 0.9 4区医学

Issues in Law & Medicine Pub Date : 2017-01-01

Patrick James Baggot, Rocel Medina Baggot

{"title":"Fetal Therapy for Down Syndrome: Report of Three Cases and a Review of the Literature.","authors":"Patrick James Baggot, Rocel Medina Baggot","doi":"","DOIUrl":"","url":null,"abstract":"Background: Down syndrome (trisomy 21) is a well-known cause of mental retardation. It can be diagnosed in early pregnancy. Scientists have made great strides in outlining the pathophysiologic mechanisms of mental retardation in Down syndrome. Much less has been published on human therapy. To our knowledge, these are the first published cases of fetal therapy for Down syndrome.Methodology: Reports of three cases. In all cases, treatment was both biochemical (e.g. nutritional) and educational. In all cases, treatment was both before and after birth.Results: All children lacked the characteristic faces usually seen in the children with Down syndrome. This suggests a treatment effect before birth. All children had better than expected development.Discussion: Enhancement of development is proposed as a new therapeutic principle. Developing neurons exchange neurotrophic factors during development when they give or receive stimulation from other neurons. Neurons which receive neurotrophic stimulation survive, and those, which do not, are lost to apoptosis. The developmental therapeutic principle seeks to optimize brain development. Biochemical inputs (neurotransmitters, drugs, hormones, nutrients) and functional stimulation are integrated to optimize the growth and survival of neurons individually; other cells; subcellular organelles; and the brain as a whole. Treatment may be before and after birth, both biochemical and functional. These principles may be applied to Down syndrome, other conditions, and normal fetuses or children.Previously published: Baggot PJ and Baggot RM (2014). Fetal Therapy for Down Syndrome: Report of three cases and review of the literature. J Am Phys Surg 19(1):20-24.","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 1","pages":"31-41"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35580422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Teaching OB/GYN residents bioethics within a Catholic healthcare context. 在天主教医疗保健背景下教授妇产科住院医生生物伦理学。

IF 0.9 4区医学

Issues in Law & Medicine Pub Date : 2017-01-01

Andrew Steele

{"title":"Teaching OB/GYN residents bioethics within a Catholic healthcare context.","authors":"Andrew Steele","doi":"","DOIUrl":"","url":null,"abstract":"Residents entering training in the specialty of Obstetrics and Gynecology (OB/GYN) often have misconceptions as to what medical interventions Roman Catholic healthcare institutions prohibit, and why certain restrictions are placed on the provision of reproductive health options that are otherwise legally available to women. The Ethical and Religious Directives for Catholic Healthcare Services, produced by the United States Conference of Catholic Bishops seeks to provide a stable framework upon which reproductive health decisions can be based. However, Catholic healthcare ethics may conflict with secular bioethical assertions that place a premium on autonomous patient choice. Residents training in part or whole at a Catholic institution may feel frustration at what they perceive to be a conflict with current secular ethics paradigms-such as access to abortion, contraception, sterilization, and assisted reproductive technologies. The recent adoption of Clinical Competencies by the Accreditation Council for Graduate Medical Education (ACGME), directs that residents shall be trained to function within the framework of their larger healthcare system (\"Systems-based Practice\"). This article will first, clarify areas of conflict and convergence between Catholic and secular reproductive ethics, which are unique to OB/GYN training. Next, using the ACGME's new Clinical Competency in Systems-Based practice as a model, a rationale for incorporating Catholic Healthcare ethics into an ethics curriculum for OB/GYN residents will be discussed. Finally, guidelines for faculty tackling the problem of how to teach Catholic Healthcare ethics will be described. Incorporating the rich tradition of Catholic healthcare ethics into the educational curriculum of OB/GYN residency fulfills training requirements while exposing young physicians to a rational decision-making framework in bioethics.","PeriodicalId":48665,"journal":{"name":"Issues in Law & Medicine","volume":"32 2","pages":"173-182"},"PeriodicalIF":0.9,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35579491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Upholding the sanctity of life in a culture of death. 在死亡文化中维护生命的神圣。

IF 0.9 4区医学

Issues in Law & Medicine Pub Date : 2017-01-01

Richard Weikart

引用次数: 0

Abortion-breast cancer link: review of recent evidence from Asia. 流产与乳腺癌的联系:对亚洲近期证据的回顾。

IF 0.9 4区医学

Issues in Law & Medicine Pub Date : 2017-01-01

Joel Brind

引用次数: 0

Overruling Roe v. Wade: the implications for the law. 推翻罗伊诉韦德案:对法律的影响。