{"title":"Commentary: Commando Operation - For the \"Elite\".","authors":"Tsuyoshi Kaneko, Thierry Carrel","doi":"10.1053/j.semtcvs.2025.04.003","DOIUrl":"https://doi.org/10.1053/j.semtcvs.2025.04.003","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Travis C Geraci, Justin C Y Chan, Anna Niroomand, Stephanie H Chang
{"title":"Post Lung Transplant Primary Graft Dysfunction.","authors":"Travis C Geraci, Justin C Y Chan, Anna Niroomand, Stephanie H Chang","doi":"10.1053/j.semtcvs.2025.04.001","DOIUrl":"https://doi.org/10.1053/j.semtcvs.2025.04.001","url":null,"abstract":"<p><p>Primary graft dysfunction (PGD) is a major source of morbidity and mortality following lung transplantation, presenting as acute lung injury within 72 hours post-transplantation. Despite advances in surgical techniques and perioperative care, the complex interplay of donor, recipient, and perioperative factors contributes to its development, underscoring the multifactorial nature of PGD. Clinical management of recipients with PGD relies on supportive care strategies, including lung-protective ventilation, inhaled nitric oxide, and extracorporeal membrane oxygenation (ECMO). Severe cases of PGD may result in significant short- and long-term adverse outcomes, including early mortality. Even for patients who recover from PGD, there is also an associated increased risk of chronic lung allograft dysfunction, further compounding its clinical impact. This review provides a brief review of current knowledge regarding PGD, detailing risk factors, diagnostic criteria, and management approaches while identifying critical gaps in understanding its pathophysiology. Ongoing research is essential to develop innovative therapeutic strategies and improve outcomes for lung transplant recipients.</p>","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Morgan K Moroi, Alice V Vinogradsky, Amee Shah, Kanwal Farooqi, Oliver Barry, Emile Bacha, David M Kalfa
{"title":"When to Opt for Univentricular versus Biventricular Repair in Complex Congenitally Corrected Transposition of the Great Arteries.","authors":"Morgan K Moroi, Alice V Vinogradsky, Amee Shah, Kanwal Farooqi, Oliver Barry, Emile Bacha, David M Kalfa","doi":"10.1053/j.semtcvs.2025.03.012","DOIUrl":"https://doi.org/10.1053/j.semtcvs.2025.03.012","url":null,"abstract":"<p><p>The surgical management of complex congenitally corrected transposition of the great arteries (ccTGA) remains a subject of ongoing debate due to wide anatomic variability and limited comparative outcomes data. Available strategies include the anatomic repair, physiologic repair, 1.5-ventricular repair, and biventricular repair, each selected based on anatomic severity and the presence of associated lesions. This commentary reviews the existing literature to inform decision-marking between univentricular, 1.5-ventricular, and biventricular repair strategies in complex ccTGA and underscores the need for further comparative studies to guide management.</p>","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giulio Folino, Raffaele Scaffa, Andrea Salica, Mario Torre, Ruggero De Paulis
{"title":"The Anatomy and Physiology of Aortic Root Repair.","authors":"Giulio Folino, Raffaele Scaffa, Andrea Salica, Mario Torre, Ruggero De Paulis","doi":"10.1053/j.semtcvs.2025.03.009","DOIUrl":"https://doi.org/10.1053/j.semtcvs.2025.03.009","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Travis J Miles, Kyle W Blackburn, Marc R Moon, Subhasis Chatterjee
{"title":"Optimal Inotropic Support Strategy in Low Cardiac Output Syndrome.","authors":"Travis J Miles, Kyle W Blackburn, Marc R Moon, Subhasis Chatterjee","doi":"10.1053/j.semtcvs.2025.04.002","DOIUrl":"https://doi.org/10.1053/j.semtcvs.2025.04.002","url":null,"abstract":"<p><p>Low cardiac output syndrome (LCOS), a form of cardiogenic shock that occurs after cardiac surgery, is associated with an elevated risk of morbidity and mortality. Generally, LCOS is managed medically with inotropes and vasopressors to optimize hemodynamics. However, randomized data comparing the efficacy of individual inotropes in treating LCOS are limited. Consequently, there is little consensus regarding the optimal inotrope strategy, and practice patterns vary widely. This review synthesizes current evidence on pharmacologic, non-mechanical circulatory support strategies for managing LCOS, advocating for a personalized approach tailored to the individual patient's hemodynamic profile and inotropic requirements. Currently available vasoactive agents are discussed, and guidance is provided on their use across specific clinical contexts to support individualized treatment.</p>","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adjuvant Therapy in Stage IB Non-Small Cell Lung Cancer: A Network Meta-Analysis of Tegafur-Uracil and Immune Checkpoint Inhibitors.","authors":"Masatsugu Hamaji, Jiro Takeuchi, Naoki Ozu, Ryo Miyata, Keiji Yamanashi, Takeshi Kawaguchi, Mitsuharu Hosono","doi":"10.1053/j.semtcvs.2025.03.011","DOIUrl":"https://doi.org/10.1053/j.semtcvs.2025.03.011","url":null,"abstract":"<p><p>Recent clinical trials demonstrated that as adjuvant therapy, immune checkpoint inhibitors (ICIs) following intravenous cytotoxic chemotherapy may have a nonsignificant advantage over intravenous cytotoxic chemotherapy only in completely resected stage IB non-small cell lung cancer (NSCLC). Meanwhile, several studies reported that oral tegafur-uracil may have a comparable benefit to intravenous chemotherapy in long-term survival outcomes in these patients. However, there is currently a lack of head-to-head comparison between ICIs following intravenous cytotoxic chemotherapy and tegafur-uracil. Therefore, we designed a network meta-analysis in assessing overall survival (OS) and a composite endpoint of disease free survival (DFS) and recurrence free survival (RFS) as measures of effect. Our results indicated that, limited to stage IB, calculated hazard ratio (HR) was 1.02 (95% confidence interval [CI]: 0.53-1.96) for OS and calculated HR was 0.90 (95% CI: 0.43-1.87) for DFS, while in stage IB to IIIA patients, calculated HR was 0.97 (95% CI: 0.70-1.37) for OS and calculated HR was 0.75 (95% CI: 0.59-0.95) for DFS. In conclusion, tegafur-uracil may offer a comparable benefit to ICIs following chemotherapy in limitation to stage IB NSCLC patients only. Future clinical trials may be designed for stage IB NSCLC, separately from stage II and III.</p>","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experience Working With 3rd Party: Lung Bioengineering.","authors":"Caitlin T Demarest","doi":"10.1053/j.semtcvs.2025.03.010","DOIUrl":"https://doi.org/10.1053/j.semtcvs.2025.03.010","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suguru Ohira, Sooyun Caroline Tavolacci, Corazon de la Pena, David Spielvogel
{"title":"Outcomes of Redo Aortic Arch Repair Post Type A Dissection in the Modern Era.","authors":"Suguru Ohira, Sooyun Caroline Tavolacci, Corazon de la Pena, David Spielvogel","doi":"10.1053/j.semtcvs.2025.03.006","DOIUrl":"https://doi.org/10.1053/j.semtcvs.2025.03.006","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Just Short of the Silver Medal: The Radial is a Close Third to the Right Internal Thoracic Artery in the Hierarchy of Arterial Coronary Bypass Grafts.","authors":"Michael Salna, Michael Argenziano, Craig R Smith","doi":"10.1053/j.semtcvs.2025.01.009","DOIUrl":"10.1053/j.semtcvs.2025.01.009","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jagdip Kang, Antonia van Kampen, Maja-Theresa Dieterlen, Ricardo Spampinato, Thoralf Sundt, Serguei Melnitchouk, Robert A Levine, Michael A Borger
{"title":"Arrhythmic Mitral Valve Prolapse: Pathophysiology, Diagnostics, and Management Strategies.","authors":"Jagdip Kang, Antonia van Kampen, Maja-Theresa Dieterlen, Ricardo Spampinato, Thoralf Sundt, Serguei Melnitchouk, Robert A Levine, Michael A Borger","doi":"10.1053/j.semtcvs.2025.03.005","DOIUrl":"10.1053/j.semtcvs.2025.03.005","url":null,"abstract":"<p><p>Mitral valve prolapse (MVP) is a common disease in which ventricular arrhythmias/sudden cardiac death can be the first symptom of presentation. This review article explores the current understanding of underlying pathological mechanisms leading to an increased risk for ventricular arrhythmias in the setting of MVP and elaborates on the current evidence regarding the diagnosis and management of the disease.</p>","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}