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Determinants of childhood immunization coverage in Somalia: evidence from the Somalia Demographic and Health Survey 2020. 索马里儿童免疫覆盖率的决定因素:来自2020年索马里人口与健康调查的证据。
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-05-09 DOI: 10.1186/s13690-026-01924-0
Sharmake Gaiye Bashir, Yakub Burhan Abdullahi, Yusuf Hared Abdi, Hiba Abdi Salad, Mohamed Sharif Abdi, Naima Ibrahim Ahmed, Nuradin Abdullahi Sheikh Rashid, Obasanjo Bolarinwa, Ahmed Abdinasir Abdulle
{"title":"Determinants of childhood immunization coverage in Somalia: evidence from the Somalia Demographic and Health Survey 2020.","authors":"Sharmake Gaiye Bashir, Yakub Burhan Abdullahi, Yusuf Hared Abdi, Hiba Abdi Salad, Mohamed Sharif Abdi, Naima Ibrahim Ahmed, Nuradin Abdullahi Sheikh Rashid, Obasanjo Bolarinwa, Ahmed Abdinasir Abdulle","doi":"10.1186/s13690-026-01924-0","DOIUrl":"https://doi.org/10.1186/s13690-026-01924-0","url":null,"abstract":"<p><strong>Background: </strong>Somalia has one of the lowest childhood immunization coverage rates globally, with only 34.8% of children aged 0-59 months having received at least one vaccine and a high burden of zero-dose children. Immunization uptake is influenced by socioeconomic, maternal, healthcare access, and geographic factors. This study examined determinants of childhood immunization coverage in Somalia to inform equity-focused strategies.</p><p><strong>Methods: </strong>A cross-sectional analysis was conducted using nationally representative data from the 2020 Somalia Demographic and Health Survey (SDHS), including 7,373 mother-child pairs. bivariate and multivariable logistic regression models assessed associations between sociodemographic, economic, maternal, healthcare access, and geographic characteristics and child vaccination status, accounting for survey design and confounders.</p><p><strong>Results: </strong>Overall vaccination coverage was 34.8%. Health facility delivery was the strongest independent predictor (AOR = 1.93; 95% CI:1.68-2.22; p < 0.001). Children from the highest household wealth quintile had higher odds than the poorest (AOR = 2.45; 95% CI:2.00-3.00; p < 0.001). Maternal primary and secondary education were positively associated with vaccination (AOR = 1.58; 95% CI:1.34-1.87 and AOR = 1.94; 95% CI:1.40-2.67; respectively; p < 0.001). Nomadic residence was associated with higher odds compared with rural residence (AOR = 1.69; 95% CI:1.46-1.96; p < 0.001). Compared with infants aged 0-11 months, children aged 12-23 months (AOR = 1.36; 95% CI:1.10-1.69; p = 0.005) and 24-59 months (AOR = 1.33; 95% CI:1.12-1.59; p = 0.001) were more likely to be vaccinated. Lack of radio exposure was associated with lower vaccination odds (AOR = 0.64; 95% CI:0.50-0.82; p < 0.001). Children living in Gedo region had markedly lower odds of vaccination than those in Awdal region (AOR = 0.26; 95% CI:0.17-0.39; p < 0.001).</p><p><strong>Conclusions: </strong>Childhood immunization coverage in Somalia remains critically low, reflecting socioeconomic, maternal, healthcare access, and geographic inequalities that require strategies targeting disadvantaged populations and regions.</p>","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frailty trajectories and mortality prediction among Japanese community-dwelling older adults: a cohort study comparing time-based and age-based models. 日本社区老年人的衰弱轨迹和死亡率预测:一项比较基于时间和基于年龄模型的队列研究。
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-05-08 DOI: 10.1186/s13690-026-01928-w
Mengjiao Yang, Yang Liu, Mingyu Cui, Dandan Jiao, Yuko Sawada, Akihiro Kakuda, Shuanghong Li, Jinrui Zhang, Meiling Qian, Lujiao Huang, Tokie Anme
{"title":"Frailty trajectories and mortality prediction among Japanese community-dwelling older adults: a cohort study comparing time-based and age-based models.","authors":"Mengjiao Yang, Yang Liu, Mingyu Cui, Dandan Jiao, Yuko Sawada, Akihiro Kakuda, Shuanghong Li, Jinrui Zhang, Meiling Qian, Lujiao Huang, Tokie Anme","doi":"10.1186/s13690-026-01928-w","DOIUrl":"https://doi.org/10.1186/s13690-026-01928-w","url":null,"abstract":"<p><strong>Background: </strong>Group-based trajectory modeling (GBTM) can be applied using either time-based or age-based approaches to identify frailty trajectories; however, the comparative effectiveness of the methods for mortality prediction remains unclear. This study aimed to compare time-based and age-based trajectory modeling in identifying frailty trajectories and their predictive value for mortality among Japanese community-dwelling older adults.</p><p><strong>Methods: </strong>Of 1085 community-dwelling older adults aged ≥ 65 years, 512 participants with at least two frailty assessments who remained independent during 2011-2017 were included. Frailty was assessed using the Kihon Checklist. Both time-based and age-based GBTM used data from 2011, 2014, and 2017 to identify trajectories. Agreement between methods was assessed using Cohen's Kappa coefficient. Kaplan-Meier survival analysis and Cox proportional hazards models were used to evaluate mortality prediction during follow-up (May 2017-March 2021).</p><p><strong>Results: </strong>Among the 512 participants (mean age 72 ± 6 years; 54.7% female), both models identified two frailty trajectories: low increasing (88.3% vs. 83.8%) and high increasing (11.7% vs. 16.2%) groups for the time-based and age-based models, respectively. The methods showed substantial agreement (Kappa = 0.63, P < 0.001). During follow-up, 48 participants (9.4%) died, with a median survival time of 27 (IQR 18-33) months. The high increasing group showed a higher mortality risk than the low increasing group in the time-based (adjusted HR = 3.0, 95% CI = 1.4-6.5, P = 0.006) and age-based models (adjusted HR = 2.5, 95% CI = 1.2-5.1, P = 0.01). Both models showed comparable discriminative ability (C-index: 0.77 vs. 0.77) and model fit (AIC: 451 vs. 453).</p><p><strong>Conclusions: </strong>In this three-wave Japanese community-based older adult study, both time-based and age-based GBTM identified similar two-group frailty trajectories with substantial agreement and effectively identified high-risk populations for mortality. These findings suggest that both modeling methods are suitable for frailty trajectory analysis and mortality risk prediction in this population; however, their generalizability to other populations requires further validation.</p>","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-sectional analysis of odor exposure, household pesticides, and chlorpyrifos residues in flies in Chilean rural communities. 智利农村地区蝇类气味暴露、家用农药和毒死蜱残留的横断面分析。
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-05-08 DOI: 10.1186/s13690-026-01936-w
Sebastián Pozo, Rocío Hojas, José Norambuena, Joaquín Toro, América Ponce, Jandy Adonis, Francisca Cabezas, Bárbara Figueroa, Cristian Valdés, Liliana Zúñiga-Venegas, Benjamín Castillo, Boris Lucero, Cynthia Carrasco, Juan Pablo Gutiérrez-Jara, Natalia Landeros, María Teresa Muñoz-Quezada
{"title":"Cross-sectional analysis of odor exposure, household pesticides, and chlorpyrifos residues in flies in Chilean rural communities.","authors":"Sebastián Pozo, Rocío Hojas, José Norambuena, Joaquín Toro, América Ponce, Jandy Adonis, Francisca Cabezas, Bárbara Figueroa, Cristian Valdés, Liliana Zúñiga-Venegas, Benjamín Castillo, Boris Lucero, Cynthia Carrasco, Juan Pablo Gutiérrez-Jara, Natalia Landeros, María Teresa Muñoz-Quezada","doi":"10.1186/s13690-026-01936-w","DOIUrl":"https://doi.org/10.1186/s13690-026-01936-w","url":null,"abstract":"<p><strong>Background: </strong>The expansion of agricultural and livestock production has increased environmental and health concerns for rural communities living near these activities. The aim was to assess odor perception, health conditions, household pesticide use, and the presence of chlorpyrifos residues in flies in rural communities located near a swine production facility in the Maule Region, Chile.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 82 adults residing within approximately 10 km of the \"El Arbolillo\" area in Maule Region, Chile. Structured questionnaires assessed odor perception, health conditions, and domestic pesticide use. Flies were collected in a subsample of households (n = 17), and chlorpyrifos residues were analyzed using gas chromatography-tandem mass spectrometry.</p><p><strong>Results: </strong>A total of 61% of participants rated odors as extremely strong. Household pesticide use was reported by 69% and was more frequent in homes located closer to the facility (p = 0.001), and associated with higher odor discomfort (p = 0.006). Chlorpyrifos residues were detected in 68% of sampled households (median: 0.106 ng mg⁻¹). After adjustment for age and sex, higher odor discomfort was associated with hypertension (OR = 3.28; 95% CI: 1.46-9.39), reflux/gastritis (OR = 3.34; 95% CI: 1.23-9.08), shortness of breath (OR = 2.72; 95% CI: 1.05-7.05), and loss of appetite (OR = 2.91; 95% CI: 1.08-7.81). Household pesticide use was associated with migraine (OR = 5.06; 95% CI: 1.40-18.3), gastritis/ulcer (OR = 6.09; 95% CI: 1.53-24.3), and allergic contact eczema (OR = 5.31; 95% CI: 1.22-23.1).</p><p><strong>Conclusions: </strong>These findings describe co-occurring environmental exposures, including odor, domestic pesticide use, and pesticide residues in flies. The results support the need for strengthened environmental surveillance and mitigation measures in affected communities.</p><p><strong>Trial registration: </strong>Not applicable.</p>","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From feminine hygiene to intimate cosmetics: why language matters for vulvovaginal product exposures and regulation. 从女性卫生到私密化妆品:为什么语言对外阴阴道产品暴露和调节很重要。
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-05-07 DOI: 10.1186/s13690-026-01921-3
Elissia T Franklin, Shanique K E Edwards, Devon M Price, Adana A M Llanos
{"title":"From feminine hygiene to intimate cosmetics: why language matters for vulvovaginal product exposures and regulation.","authors":"Elissia T Franklin, Shanique K E Edwards, Devon M Price, Adana A M Llanos","doi":"10.1186/s13690-026-01921-3","DOIUrl":"10.1186/s13690-026-01921-3","url":null,"abstract":"<p><strong>Background: </strong>Terminology used to describe products applied to the vulva and vagina is inconsistent and poorly standardized, limiting clarity in research, clinical practice, and regulation. Products marketed under the umbrella of \"feminine hygiene\" or \"intimate care\" include both menstrual management items and products intended primarily for aesthetic purposes, such as douches, sprays, wipes, and scented tampons. The use of health-oriented language such as \"hygiene\" and \"care\" may imply medical necessity or health benefit despite limited evidence of therapeutic value and growing concern regarding chemical exposures associated with some of these products. Ambiguous terminology may obscure product function, hinder risk communication, and contribute to regulatory and research gaps.</p><p><strong>Main body: </strong>We propose the term intimate cosmetics to describe vulvovaginal products intended for aesthetic purposes rather than for menstrual management. This terminology aligns with established regulatory definitions of cosmetics as products applied to the body for cleansing, beautifying, or altering appearance, without implying disease prevention or treatment. Reframing these products as cosmetics more accurately reflects their intended use and clarifies distinctions between aesthetic and health-promoting interventions. Many intimate cosmetics contain fragrances and other chemicals associated with endocrine disruption, reproductive toxicity, or carcinogenicity, yet marketing claims such as \"gynecologist tested\" or \"pH balanced\" may confer an impression of clinical legitimacy. Clear, function-based terminology can improve research categorization, enhance post-market safety monitoring, and support more transparent regulatory oversight. Importantly, imprecise and gendered language may also reinforce stigma and obscure patterns of disproportionate exposure among populations already overburdened by environmental toxicants.</p><p><strong>Conclusion: </strong>Adopting the term intimate cosmetics represents a practical public health strategy to improve precision in scientific discourse, strengthen risk communication, and promote more equitable regulatory attention. Intentional, function-based nomenclature can better align product labeling, research, and policy with exposure realities and consumer protection goals.</p>","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":"84 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13151276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A body shape index trajectories and cognitive function among older hypertensive patients: a national cohort study. 老年高血压患者的体型指数轨迹和认知功能:一项国家队列研究。
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-05-01 DOI: 10.1186/s13690-026-01925-z
Yueming Ding, Tongtong Sheng, Zixuan Zhang, Ke Shen, Rui Meng, Yanjun Sun, Yuan He
{"title":"A body shape index trajectories and cognitive function among older hypertensive patients: a national cohort study.","authors":"Yueming Ding, Tongtong Sheng, Zixuan Zhang, Ke Shen, Rui Meng, Yanjun Sun, Yuan He","doi":"10.1186/s13690-026-01925-z","DOIUrl":"https://doi.org/10.1186/s13690-026-01925-z","url":null,"abstract":"<p><strong>Background: </strong>While several cross-sectional studies have suggested an association between a body shape index (ABSI) and cognitive decline, the relationship between longitudinal ABSI patterns and cognitive outcomes among older hypertensive patients remains unclear. This study aimed to investigate the association between ABSI trajectories and cognitive outcomes in this population using a longitudinal cohort design.</p><p><strong>Methods: </strong>Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS), with ABSI measurements collected in 2011, 2013, and 2015. Group-based trajectory modeling (GBTM) was used to identify the distinct ABSI trajectories. Cox proportional hazards models and linear mixed-effects models were applied to evaluate the association between ABSI trajectories and cognitive function among older hypertensive patients.</p><p><strong>Results: </strong>A total of 1,065 older hypertensive participants were included in the study (572 males, 53.7%; 493 females, 46.3%). Three ABSI trajectory groups were identified: moderate-stable (n = 602, 56.5%), low-rapid-rising (n = 144, 13.5%), and high-slightly-increasing (n = 319, 30.0%). After adjusting for potential confounders, there was borderline evidence of effect modification by sex for incident low cognitive performance defined by a Z-score cutoff (P for interaction = 0.046). Compared with low-rapid-rising trajectory group, hazard ratio point estimates were higher in women (moderate-stable trajectory group: HR = 1.57, 95% CI 0.81-3.03; high-slightly-increasing trajectory group: HR = 1.83, 95% CI 0.94-3.58) but lower in men (moderate-stable trajectory group: HR = 0.78, 95% CI 0.48-1.27; high-slightly-increasing trajectory group: HR = 0.63, 95% CI 0.36-1.09), although sex-stratified estimates were imprecise, with confidence intervals crossing the null. In mixed-effects models of global cognitive Z-scores, baseline cognition was similar across groups; moderate-stable trajectory group showed a less steep decline than low-rapid-rising trajectory group (moderate-stable trajectory group×time: β = 0.05, 95% CI: 0.00-0.10), whereas high-slightly-increasing trajectory group was similar, with no evidence of sex modification of slopes.</p><p><strong>Conclusions: </strong>Long-term ABSI trajectories showed heterogeneous associations with cognitive outcomes in older hypertensive patients, with potential sex-related heterogeneity for incident low cognitive performance. Defining incident events by first crossing a Z-score cutoff may capture earlier cognitive vulnerability before clinically diagnosed impairment, offering a prevention-relevant perspective on longitudinal changes in ABSI among older adults with hypertension. However, sex-specific estimates were imprecise, and replication in larger, independent cohorts is warranted.</p>","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147822380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Life's essential 8 in relation to incident cardiovascular disease and mortality: the prospective study of Isfahan cohort study (2001-2013). 生命要素与心血管疾病和死亡率的关系:Isfahan队列研究的前瞻性研究(2001-2013)。
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-04-30 DOI: 10.1186/s13690-026-01874-7
Shahnaz Amani Tirani, Motahare Bateni, Parisa Hajihashemi, Noushin Mohammadifard, Marzieh Taheri, Maryam Boshtam, Jamshid Najafian, Mansoureh Boshtam, Fahimeh Haghighatdoost, Nizal Sarrafzadegan
{"title":"Life's essential 8 in relation to incident cardiovascular disease and mortality: the prospective study of Isfahan cohort study (2001-2013).","authors":"Shahnaz Amani Tirani, Motahare Bateni, Parisa Hajihashemi, Noushin Mohammadifard, Marzieh Taheri, Maryam Boshtam, Jamshid Najafian, Mansoureh Boshtam, Fahimeh Haghighatdoost, Nizal Sarrafzadegan","doi":"10.1186/s13690-026-01874-7","DOIUrl":"https://doi.org/10.1186/s13690-026-01874-7","url":null,"abstract":"","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in place of death in Peru, 2017-2024: a nationwide analysis. 2017-2024年秘鲁死亡地点趋势:一项全国分析。
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-04-27 DOI: 10.1186/s13690-026-01872-9
Brayan Miranda-Chavez, Karla Manrique-Hipólito, José Amado-TIneo, Rubí Paredes-Angeles, Alvaro Taype-Rondan
{"title":"Trends in place of death in Peru, 2017-2024: a nationwide analysis.","authors":"Brayan Miranda-Chavez, Karla Manrique-Hipólito, José Amado-TIneo, Rubí Paredes-Angeles, Alvaro Taype-Rondan","doi":"10.1186/s13690-026-01872-9","DOIUrl":"https://doi.org/10.1186/s13690-026-01872-9","url":null,"abstract":"","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":"84 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13112657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How urban environments structure running behaviour in Beijing during winter, spring, and summer 2024: spatiotemporal patterns and configuration-specific interactions from running trajectory data. 2024年冬、春、夏北京城市环境对跑步行为的影响:来自跑步轨迹数据的时空模式和特定配置的相互作用
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-04-27 DOI: 10.1186/s13690-026-01919-x
Cailin Qiu, Chendi Zhang, Ning Qiu, Xinyu Han, Tianjie Zhang
{"title":"How urban environments structure running behaviour in Beijing during winter, spring, and summer 2024: spatiotemporal patterns and configuration-specific interactions from running trajectory data.","authors":"Cailin Qiu, Chendi Zhang, Ning Qiu, Xinyu Han, Tianjie Zhang","doi":"10.1186/s13690-026-01919-x","DOIUrl":"https://doi.org/10.1186/s13690-026-01919-x","url":null,"abstract":"","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L-shaped association of skeletal muscle mass with all-cause mortality among US adults: a population-based cohort study. 美国成年人骨骼肌质量与全因死亡率的l型关联:一项基于人群的队列研究。
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-04-25 DOI: 10.1186/s13690-026-01920-4
Jinhua Chen, Yundan Bai, Xinyi Zhao, Yijun Tang, Yongjie Deng
{"title":"L-shaped association of skeletal muscle mass with all-cause mortality among US adults: a population-based cohort study.","authors":"Jinhua Chen, Yundan Bai, Xinyi Zhao, Yijun Tang, Yongjie Deng","doi":"10.1186/s13690-026-01920-4","DOIUrl":"https://doi.org/10.1186/s13690-026-01920-4","url":null,"abstract":"<p><strong>Background: </strong>The predicted skeletal muscle mass index (pSMI), derived from the serum creatinine-to-cystatin C ratio (CCR), has emerged as a novel biomarker for predicting the onset of type 2 diabetes mellitus. However, its application remains primarily limited to East Asian populations, and the relationship between pSMI and mortality in general populations remains unclear. Therefore, this study aimed to investigate the association between pSMI and all-cause mortality in a nationally representative US adult population.</p><p><strong>Methods: </strong>We analyzed data from three cycles (1999-2004) of the National Health and Nutrition Examination Survey (NHANES). pSMI levels were analyzed both as a continuous variable and categorized into tertiles. To assess the association between pSMI and all-cause mortality, we performed multivariable Cox regression, restricted cubic spline (RCS) analysis, and Kaplan-Meier survival analysis.</p><p><strong>Results: </strong>During a median follow-up of 193.2 months (2217 deaths), multivariable-adjusted analyses revealed that higher pSMI levels were significantly associated with reduced all-cause mortality (HR 0.76, 95% CI 0.72-0.80; p < 0.001). Compared to the lowest tertile (T1:4.98-7.83), T2 (7.84-9.18) and T3 (9.19-19.24) showed progressively lower mortality risks (T2: HR 0.79, 95% CI 0.67-0.94, p = 0.009; T3: HR 0.66, 95% CI 0.50-0.88, p = 0.004). Restricted cubic spline analysis demonstrated an L-shaped association (p for non-linear = 0.003) with an inflection point at 10.0 (HR 0.632, 95% CI 0.543-0.721; p < 0.001). Sex-stratified analyses revealed inflection points at 10.5 (males) and 7.6 (females). Kaplan-Meier analysis confirmed significantly improved survival with higher pSMI levels (all p < 0.001 for total population, males and females).</p><p><strong>Conclusions: </strong>This study identifies pSMI as an independent predictor of lower all-cause mortality, revealing a nonlinear L-shaped association with a distinct threshold effect. The protective relationship remains consistent across both sexes, though with differing inflection points. These findings highlight the clinical importance of assessing skeletal muscle mass for mortality risk stratification.</p>","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Testing nature-based biopsychosocial resilience theory: a research programme protocol. 测试基于自然的生物心理社会弹性理论:一个研究项目协议。
IF 3.2 3区 医学
Archives of Public Health Pub Date : 2026-04-24 DOI: 10.1186/s13690-026-01903-5
Mathew P White, Julia A M Egger, Giulia Amato, Thomas Astell-Burt, Stine Bekke-Hansen, Angel Borja, Angel Burov, Svea Busse, Caroline Costongs, Donka Dimitrova, Ilaria Doimo, Angel M Dzhambov, Lewis R Elliott, Alba Godfrey, James Grellier, Terry Hartig, Arnulf Hartl, Patrik Karlsson Nyed, Cecil Konijnendijk, Melissa Lem, Jill S Litt, Rebecca Lovell, Freddie Lymeus, Aynur Mammadova, Leanne Martin, Angelica Moè, Sarah Morgan Trimmer, Colm O'Driscoll, Johan Östberg, Sabine Pahl, Francesca Pazzaglia, Christina Pichler, Alexandria Poole, Sarai Pouso, Nooshin Razani, Todora Rogelja, Laura Secco, Ulrika K Stigsdotter, Sus Sola Corazon, Georgina Sowman, Maria C Uyarra, Agnes E van den Berg, Thomas van Rompay, Martin Voracek, Nancy M Wells, Benedict W Wheeler, Matilda van den Bosch
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