African Journal of Emergency Medicine最新文献

{"title":"Pattern of admissions and outcome in the children emergency department of a tertiary health institution in Southwestern Nigeria: A four-year review","authors":"Tosin Anthony Agbesanwa ,&nbsp;Adefunke Olarinre Babatola ,&nbsp;Odunayo Adebukola Fatunla ,&nbsp;Azeez Ibrahim ,&nbsp;Felix O Aina ,&nbsp;Ezra Olatunde Ogundare ,&nbsp;Adewuyi Temidayo Adeniyi ,&nbsp;Funmilayo Egbedi ,&nbsp;Tinu Olubamiwa ,&nbsp;Bolanle Olanipekun ,&nbsp;Oladele Simeon Olatunya","doi":"10.1016/j.afjem.2023.02.001","DOIUrl":"10.1016/j.afjem.2023.02.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Pediatrics and adolescents are susceptible to illnesses that often necessitate emergency attention. Morbidity and mortality from illnesses in these ages have attracted much interest globally, particularly in Africa. Knowledge of pattern and outcomes of admissions may guide policy and interventions especially in resource constrained settings. The study aimed to determine the pattern of admissions, outcomes and seasonal variations of conditions that presented at the children emergency of a tertiary health institution over a four-year period.</p></div><div><h3>Methods</h3><p>A retrospective descriptive study of children emergency admissions from January 2016 to December 2019. Information obtained included age, diagnosis, month and year of admission, and outcome. Descriptive statistics were used to describe the demographic characteristics and Chi-squared test to assess their associations with the diagnoses made.</p></div><div><h3>Results</h3><p>There were 3,223 admissions. There were more males (1866; 57.9%) and more toddlers (1181; 36.6%). The highest number of admissions were observed in the year 2018 (951; 29.6%) and during the wet season (1962; 60.9%). There was an overall mortality rate of 7%; complicated malaria, gastroenteritis and meningitis were the leading causes of death. Malaria (χ2 = 135.522, p value &lt; 0.001), and gastroenteritis (χ2 = 130.883, p value &lt; 0.001) were predominant among the toddlers while sepsis (χ2 = 71.530, p value &lt; 0.001) and pneumonia (χ2 = 133.739, p value &lt; 0.001) were more among the infants. Typhoid enteritis (χ2 = 26.629, p value &lt; 0.001) and HIV (χ2 = 16.419, p value = 0.012) were commoner among the early adolescents.</p></div><div><h3>Conclusion</h3><p>The major causes of death in the study area are preventable with more of these amongst the children under the age of 5 years. There are seasonal and age-related patterns to admissions and the need for policy formulations and emergency preparations to be tailored towards these observed patterns through the year</p></div>","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 45-51"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3c/71/main.PMC9970896.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10826947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Performance of Point of Care Ultrasound Compared to Chest X-Ray in Patients with Hypoxia at a Teaching Hospital Emergency Department in Uganda","authors":"Prisca Mary Kizito ,&nbsp;Kenneth Daniel Bagonza ,&nbsp;Justine Athieno Odakha ,&nbsp;Linda Grace Nalugya ,&nbsp;Pius Opejo ,&nbsp;Anthony Muyingo ,&nbsp;Harry Chen ,&nbsp;Derek Harborne","doi":"10.1016/j.afjem.2023.02.004","DOIUrl":"10.1016/j.afjem.2023.02.004","url":null,"abstract":"<div><h3>Background</h3><p>Hypoxia is a common presentation in the Emergency Department (ED) worldwide. It affects 9-12% of hospitalized adults in Sub-Saharan Africa. Timely diagnosis of the multiple causes such as pneumonia, heart failure among others is challenging. Chest X-Ray (CXR), one of the most utilized imaging modalities has many limitations, and the gold standard (Computed Tomography scan) is inaccessible. Point of care ultrasound (PoCUS) is more available and increasingly being used, however little is known of its performance in resource limited EDs. The study aimed to assess the diagnostic performance of PoCUS compared with CXR in identifying the causes of hypoxia in the medical ED.</p></div><div><h3>Methods</h3><p>49 adults presenting with hypoxia (SP02 ≤ 88%) in the medical ED were evaluated. Ultrasound of the lungs and heart (PoCUS) was done, then CXR obtained. Lung ultrasound (LUS) was compared with CXR (first reference standard). Chest X-Ray and PoCUS were each compared to the physician diagnosis (second reference standard) to determine agreement using an acceptable disagreement cut-off of 15%.</p></div><div><h3>Results</h3><p>31% more abnormalities were identified by LUS than CXR. Lung ultrasound findings agreed with CXR in 86% of the participants with moderate reliability (ĸ=0.75). There was no significant difference between the actual findings of the two tests (X²= 2, p 0.1). Using the second reference, 82% of the CXRs were similar with weak reliability (ĸ=0.5) compared to 98% of PoCUS findings with strong reliability (ĸ=0.9). Compared to PoCUS, CXRs significantly differed from the physician diagnosis (X²= 0.85, p 0.38 vs X²= 8.5, p 0.004 respectively).</p></div><div><h3>Conclusion</h3><p>Overall, PoCUS was not inferior to CXR when compared to final physician diagnosis in identifying causes of hypoxia, and LUS and CXR had comparable performance. Significantly more abnormalities were identified on PoCUS and it demonstrated better agreement and strong reliability with the physician diagnosis than CXR. We recommend PoCUS use in patients with hypoxia attending resource limited in- and pre-hospital settings.</p></div>","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 61-67"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9499445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of handover practices between emergency department and intensive care unit nurses","authors":"Tebogo T. Mamalelala ,&nbsp;Shelley Schmollgruber ,&nbsp;Meghan Botes ,&nbsp;William Holzemer","doi":"10.1016/j.afjem.2023.03.001","DOIUrl":"10.1016/j.afjem.2023.03.001","url":null,"abstract":"<div><h3>Background</h3><p>Nurses from the emergency department (ED) and the intensive care unit (ICU) must interact during the handover procedure. Factors such as unit boundaries, the interaction between different specialities, patient acuities, and treatment adjustments generate specific negotiating and teamwork problems during the transition of patients from ED to ICU.</p></div><div><h3>Objective</h3><p>This study aimed to describe the opinions of nurses regarding the effectiveness of handover practices between nurses in the ED and ICU in a major academic hospital in Gauteng province, South Africa.</p></div><div><h3>Method</h3><p>An analytical cross-sectional survey design was used. Data were collected using a 16-item handover evaluation tool. It comprises two sections (1) biographical details and (2) 16 statements about handover quality divided into five constructs, namely information transfer, shared understanding, working atmosphere, overall handover quality, and circumstances of handover. Data analysis was done utilising descriptive and non-parametric statistics.</p></div><div><h3>Results</h3><p>The majority (51.8%; n = 115) of the handovers occurred during the day. Out of 171 nurses, there were specialist practice emergency (19.2%; n = 33) and intensive care (28.0%; n = 48) nurses. There was statistical significance in information transfer between the ED and ICU nurses. (Me = 4.0, p &lt; 0.05), compared to ICU nurses (Me = 3.0). Nurse specialist and non-specialist nurses' handovers differed statistically significantly on 12 of the 16 items on the rating scale, compared to 10 for non-specialist nurses' handovers.</p></div><div><h3>Conclusion</h3><p>The study showed that ED and ICU nurses have significantly different requirements and expectations for handover procedures. In addition to completed documentation, subtle interpretations of the information provided and received also impact the need. The ED and ICU nurses would need to agree on the contents of a structured handover framework because different specialities and departments have varied expectations to achieve an effective handover.</p></div>","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 72-77"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9560628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging tele-mentoring and remote learning to strengthen the emergency care capacity of health workers in Uganda","authors":"Irene Atuhairwe ,&nbsp;Annet Alenyo Ngabirano ,&nbsp;Bonaventure Ahaisibwe ,&nbsp;Allan Nsubuga ,&nbsp;Andrew Marvin Kanyike ,&nbsp;Raymond Bernard Kihumuro ,&nbsp;Thomas Balizzakiwa ,&nbsp;Helen Ewing ,&nbsp;Randall Ellis ,&nbsp;Leigh Forbush ,&nbsp;Oumo Joseph ,&nbsp;Marion Jane Nakyeyune ,&nbsp;John Baptist Waniaye","doi":"10.1016/j.afjem.2023.04.001","DOIUrl":"10.1016/j.afjem.2023.04.001","url":null,"abstract":"<div><h3>Background</h3><p>A robust emergency care system is a cost-effective method of reducing preventable death and disability, especially in low-and middle-income countries. To scale emergency care expertise across the country, the Uganda Ministry of Health and Seed Global Health established the Emergency Medical Services (EMS) ECHO program. We describe the process of establishing the program in a resource-limited setting, best practices, and lessons learned in Uganda.</p></div><div><h3>Methods</h3><p>Investigators conducted a mixed-methods evaluation to assess the initial 4 months’ implementation of the EMS ECHO. We conducted pre/post-program assessments of healthcare worker knowledge, self-efficacy, and professional's satisfaction with the program. The analysis compared the differences between pre/post-test scores descriptively.</p></div><div><h3>Results</h3><p>The EMS ECHO was initiated in November 2021. A phased curriculum was developed with the initial phase focusing on the ABCDE (Airway, Breathing, Circulation, Disability, and Exposure) approach to the emergency patient. This phase reached 2,030 health workers cumulatively across 200 health facilities. The majority of the participants were medical doctors (<em>n</em> = 751, 37%), and nurses (<em>n</em> = 568, 28%). Majority of participants (95%) rated the sessions as informative. On whether the ECHO sessions diminished professional isolation, 66% agreed or strongly agreed.</p></div><div><h3>Conclusions</h3><p>Similar to other ECHO program evaluation results, Uganda's EMS ECHO program improved knowledge, skills, and the development of a virtual community of practice thereby diminishing professional isolation. It also demonstrates that through a planned stepwise process, virtual learning and telementorship can be used efficiently to improve healthcare worker knowledge,skills and multiply the limited number of emergency care experts available in the country.</p></div>","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 86-93"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9746674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global health research abstracts: March ‘23","authors":"Dr. Jonathan Kajjimu","doi":"10.1016/j.afjem.2023.03.004","DOIUrl":"10.1016/j.afjem.2023.03.004","url":null,"abstract":"<div><p>The African Journal of Emergency Medicine, in partnership with several other regional emergency medicine journals, publishes abstracts from each respective journal. Abstracts are not necessarily linked to open access papers however, all abstracts are accessible without subscription.</p></div>","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 101-103"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10149393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9406367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Health research abstracts: January ‘22","authors":"","doi":"10.1016/j.afjem.2023.01.005","DOIUrl":"https://doi.org/10.1016/j.afjem.2023.01.005","url":null,"abstract":"","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 42-44"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49732543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weight estimation in two groups of Ghanaian children with chronic diseases using Broselow, Mercy, PAWPER XL and PAWPER XL-MAC tapes","authors":"Rafiuk Cosmos Yakubu ,&nbsp;Vivian Paintsil ,&nbsp;Samuel Blay Nguah","doi":"10.1016/j.afjem.2023.04.003","DOIUrl":"10.1016/j.afjem.2023.04.003","url":null,"abstract":"<div><h3>Introduction</h3><p>The performance of various weight estimation methods in children with sickle cell disease (SCD) and heart disease (HD) has not been studied. We aimed to determine and compare the accuracies of the Broselow, Mercy, PAWPER XL and PAWPER XL-MAC tapes in Ghanaian children with no known chronic diseases (controls), SCD and HD.</p></div><div><h3>Methods</h3><p>We prospectively recruited 631 children (199 with HD, 209 SCD and 223 controls) from the Komfo Anokye Teaching Hospital (KATH). Their weights were estimated using the Broselow, Mercy, PAWPER XL and PAWPER XL-MAC tapes. These estimated weights were compared to measured weight using mean percentage error (MPE), the proportion of weight estimates within ±10% (P10) and ±20% (P20) of measured weight. Bland-Altman limits of agreement (LOA) were determined to assess the precision of weight estimation and agreement with measured weight.</p></div><div><h3>Results</h3><p>The PAWPER XL, Mercy and PAWPER XL-MAC were the most accurate in all groups of children studied. All methods except the Broselow tape (BT), which performed best in the control group, had their best performance among children with SCD with negligible critical error rates (proportion of children with weight estimates &gt; 20% of their actual weight). The P20 in the various groups of children using the BT were 88.36%, 80.21% and 51.10% respectively in the control, SCD and HD groups. The Mercy, PAWPER XL and PAWPER XL MAC tapes were generally above 90% in all groups.</p></div><div><h3>Discussion</h3><p>The Mercy, PAWPER XL and PAWPER XL-MAC tapes performed significantly better than the BT in all groups of children studied. These methods of weight estimation performed best in children with SCD with very little critical error.</p></div>","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 109-113"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9485693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The views and experiences of candidates and graduates from a South African emergency medicine doctoral programme","authors":"Craig W ,&nbsp;Khan W ,&nbsp;Rambharose S ,&nbsp;Stassen W","doi":"10.1016/j.afjem.2023.03.005","DOIUrl":"10.1016/j.afjem.2023.03.005","url":null,"abstract":"<div><h3>Introduction</h3><p>With the emergency medicine speciality in its nascency in Africa, EM doctoral programmes will need to be developed to facilitate the establishment of an evidence base that is responsive to the African populace. This study aimed to understand the thoughts, experiences, and opinions of current and past candidates of a South African EM PhD programme.</p></div><div><h3>Methods</h3><p>Descriptive, qualitative, semi-structured interviews were used to gather data on PhD EM candidates and graduates.</p></div><div><h3>Findings</h3><p>Four candidates, and four graduates were interviewed. Four categories emerged from the data 1) interviewees had various motivations for starting a PhD in EM, 2) candidate expectations and learning needs were not always aligned with reality, and the challenges and opportunities for success in the PhD programme are related both 3) intrinsically (candidate) and 4) extrinsically (system).</p></div><div><h3>Discussion</h3><p>Many of the barriers noted by the participants can be related to the nascency of the EM in Africa. Participants felt underprepared for their doctorate in terms of their baseline research literacy and skill. Candidates did not receive the level of student-supervisor engagement they desired. Candidates who are also clinicians faced both academic challenges and a resource-limited healthcare system. Pre-doctoral training may upskill prospective candidates in research literacy before they officially register. Distance-learning can be sub-optimal in terms of social interaction and collaboration. A well-curriculated, competency-based programme with clear outcomes, structured teaching-learning opportunities, intentional academic support throughout the programme, can mitigate the above. Protected academic time, promotion criteria which acknowledges academic contributions, financial incentives and more joint positions between universities and clinical services are potential solutions for clinician researcher challenges. An African PhD EM programme should produce graduates who are independent researchers, skilled in academic supervision and who are impactful to African needs when contributing to the African EM knowledge economy.</p></div>","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 78-85"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9746673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Man-O-War simulator: a Low-cost manikin for training on chest tube management","authors":"Abdennour Nasri ,&nbsp;Mouna Jerbi ,&nbsp;Rim Karray ,&nbsp;Haifa Snoussi ,&nbsp;Amal Samet ,&nbsp;Aziza Talbi ,&nbsp;Hana Ksentini ,&nbsp;Imen Rejeb ,&nbsp;Olfa Chakroun-Walha ,&nbsp;Noureddine Rekik","doi":"10.1016/j.afjem.2023.01.004","DOIUrl":"10.1016/j.afjem.2023.01.004","url":null,"abstract":"<div><p>Simulation-based medical education is becoming a cornerstone in health education. Simulators are commonly expensive and not available in developing countries.</p><p>We propose a very low-cost simulator that any educator can realize. We describe here the steps to follow to develop this proposed simulator.</p></div>","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 39-41"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10826948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute organophosphorus toxicity in a regional hospital in Johannesburg, South Africa: A retrospective chart review","authors":"Vanessa Khonje ,&nbsp;Jedd Hart ,&nbsp;Jakus Venter ,&nbsp;Saisha Deonarain ,&nbsp;Saul Grossberg","doi":"10.1016/j.afjem.2023.04.002","DOIUrl":"10.1016/j.afjem.2023.04.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Intentional and accidental organophosphorus exposures pose a significant healthcare-related burden on South African communities. This study will review the demographics, characteristics and clinical course of patients presenting with features of acute organophosphorus toxicity to a regional Emergency Centre in Johannesburg, South Africa.</p></div><div><h3>Methods</h3><p>This was a retrospective chart review of all patients treated for possible acute organophosphorus toxicity from January 2020 to August 2021.</p></div><div><h3>Results</h3><p>A total of 205 patients were identified of which 134 patients were included in the study. The median age was 26 years with a male predominance (male= 56%, female=44%). 109 patients (81.3%) survived, 18 patients (13.4%) demised and the outcome of 7 patients (5.2%) was unknown. The median hospital length of stay was 8 days, (IQR= 5-13 days), and the longest hospital stay was 37 days in ICU. Atropinisation dose was significantly higher for intubated patients (median=140.0mg; IQR=90mg-219.5mg) compared to patients who were not intubated (median=60mg; IQR=20.5mg-120mg, <em>p</em> &lt; 0.05). The length of stay was significantly higher for intubated patients (median=11 days; IQR=7-15 days) compared to patients who were not intubated (median=5 days; IQR=3-8 days, <em>p</em> &lt; 0.00). There was a moderate positive correlation between atropinisation dose and length of stay (Correlation coefficient = 0.37, <em>p</em> &lt; 0.00). There was a moderate negative correlation between atropinisation dose and cholinesterase level (Correlation coefficient= - 0.39, <em>p</em> &lt; 0.00). Of those reported to have adverse effects 78.6%, were related to atropine toxicity.</p></div><div><h3>Conclusion</h3><p>Our study shows a high mortality rate secondary to organophosphorus toxicity. Significant exposures and thus higher doses of atropine were associated with increased length of stay and need for intubation. We found a high incidence of atropine-related adverse effects. More studies are needed to further establish the balance between the therapeutic and adverse effects of high-dose atropine as a treatment modality for organophosphorus toxicity.</p></div>","PeriodicalId":48515,"journal":{"name":"African Journal of Emergency Medicine","volume":"13 2","pages":"Pages 104-108"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10160343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9485691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}