International Journal of Transgender Health最新文献

{"title":"Forms of transphobia and their influence on health outcomes among transgender, nonbinary, and gender diverse individuals: a global systematic review.","authors":"Kristen Ogarrio, Reanna Durbin-Matrone, Breanna De Leon, Laura A Wright, Arjee Restar, Anneliese A Singh, Kristefer Stojanovski","doi":"10.1080/26895269.2025.2553739","DOIUrl":"10.1080/26895269.2025.2553739","url":null,"abstract":"<p><strong>Introduction: </strong>Transgender people experience health inequities, and stigma often plays an outsize role in shaping the health and lived experiences of transgender persons. We aimed to systematically review the research literature to understand how transphobia is measured and its impacts on the health of trans populations.</p><p><strong>Methods: </strong>We conducted a systematic search using PRISMA guidelines. Titles and abstracts of articles, and full texts, were screened for inclusion. We extracted the study characteristics, populations, methods, transphobia measurement, health outcomes of study, and the relationship between transphobia and health and created evidence gap maps using R.</p><p><strong>Results: </strong>This review found 187 studies that measured transphobia and its associations with mental health, substance intake, and physical health outcomes. Transphobia was predominately studied at the individual, interpersonal, and organizational levels. The Gender Minority Stress and Resilience Measure and the Everyday Discrimination Scale were the most recurring scales used to measure transphobia. Victimization, internalized transphobia, and institutional discrimination were the most reported types of transphobia. Across a majority of studies, transphobias were positively associated with poor health outcomes, with heavy emphasis on mental health outcomes, as well as substance intake. Large gaps existed with regard to physical health.</p><p><strong>Conclusions: </strong>Transphobia negatively impacts the mental health of trans people and often creates elevated substance use. Gaps exist in the measurement of transphobia at the community, organizational and structural levels, and in relation to physical health outcomes.</p>","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":" ","pages":""},"PeriodicalIF":14.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Affirming care at the margins: Community health clinics and health equity for transgender people of color.","authors":"Erin Bryant-Ross","doi":"10.1080/26895269.2025.2541986","DOIUrl":"10.1080/26895269.2025.2541986","url":null,"abstract":"","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":"27 2","pages":"631-635"},"PeriodicalIF":14.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13015067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Listening to the voices of black trans men and transmasculine people in Detroit: community strengths and challenges.","authors":"Gabriel Lee Johnson, Ini-Abasi Ubong, Rimonte A Parker, Kalaan Scott, Elijah Earnest, Elliot E Popoff, Mykell Price, Gary W Harper","doi":"10.1080/26895269.2025.2534187","DOIUrl":"https://doi.org/10.1080/26895269.2025.2534187","url":null,"abstract":"<p><strong>Background: </strong>Few transmasculine health studies have actively engaged members of the community in a participatory process of identifying the health-related issues that are most salient to their lives. Seldom have existing studies have focused their inquiries on the unique experiences of Black transgender men and transmasculine individuals. To address the unique physical and mental health needs of Black transgender men and transmasculine people in the U.S., members of these communities need to be actively engaged in all phases of the research process.</p><p><strong>Methods: </strong>Through a participatory process with a community-based organization, three community forums were conducted (<i>N</i> = 17) with a sample of majority Black trans men and transmasculine individuals from the Detroit metro area (DMA). Community forums focused on eliciting responses pertaining to how living as Black transgender man or transmasculine person influenced barriers and facilitators to their health.</p><p><strong>Results: </strong>Four themes arose across the three community forums: strengths, challenges, health topics, and program needs and recommendations. Across all four themes, participants contextualized their responses at multiple levels, from individual to cultural and structural.</p><p><strong>Conclusion: </strong>This work emphasizes the importance of bringing the voices of Black transgender men and transmasculine people to the center, allowing them to voice their own needs to shape future research and funding agendas. Future directions of research, intervention, and funding initiatives need to prioritize work conducted by and for Black transgender men and transmasculine populations to create sustainable, long-term solutions to address structural oppression faced by this population.</p>","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":" ","pages":""},"PeriodicalIF":14.8,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender-Affirming Chest Surgery in Adults with Extreme BMI: A Multi-Center Retrospective Analysis of Clinical Outcomes.","authors":"Paige N Hackenberger, Alisha L Nguyen, Rebecca Arteaga, Cole V Roblee, Maya Younoszai, Erin Sullivan, Iulianna C Taritsa, Christine D Pham, Danielle J Eble, Russell E Ettinger, Sumanas W Jordan, Shane D Morrison","doi":"10.1080/26895269.2025.2527825","DOIUrl":"https://doi.org/10.1080/26895269.2025.2527825","url":null,"abstract":"<p><strong>Background: </strong>Transgender and gender-diverse (TGD) patients face multifactorial barriers to accessing medically-necessary interventions, including gender-affirming chest surgery (GACS). Surgeons may exacerbate this inequity by imposing preoperative body mass index (BMI) requirements on their patients. Recent studies present conflicting evidence regarding the association between BMI and postoperative complications following GACS; however, no studies have assessed these outcomes in cases of extremely high BMI (>40 kg/m²).</p><p><strong>Methods: </strong>Assigned female at birth patients ≥ 18 years old undergoing GACS at three institutions were reviewed. Demographic and clinical characteristics were analyzed descriptively between patients with BMI ≤40 and >40 kg/m². A multivariable logistic model was used to determine the effect of BMI on complications.</p><p><strong>Results: </strong>647 patients were included, of these, 82 (12.7%) had BMI >40 kg/m². Among patients with BMI >40 kg/m², 21.9% had at least one complication. A significant association was observed between BMI and overall complications (p=0.0026). Adjusted analyses suggested that patients with BMI >40 kg/m2 were 2.34 times more likely to experience at least one complication (95% CI 1.153, 4.733). Overall complications, incisional dehiscence, and major complications (requiring unplanned readmission and/or reoperation) were significantly higher in patients with BMI >40 kg/m².</p><p><strong>Conclusions: </strong>This multi-institutional retrospective review demonstrates a higher frequency of adverse outcomes in patients with BMI >40 kg/m². GACS can be performed safely in patients with extreme BMI, however appropriate informed consent is necessary. These data will facilitate evidence-based counseling on the risks and benefits of GACS in this patient population.</p>","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":" ","pages":""},"PeriodicalIF":14.8,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multilevel Syndemic Profiles Impacting Optimal ART Adherence among Trans Women Living with HIV in Mumbai and New Delhi, India: A Latent Class Analysis.","authors":"William Lodge, Shruta Rawat, Alpana Dange, Jatin Chaudary, Madina Agénor, Vivek R Anand, Don Operario, Matthew J Mimiaga, Katie B Biello","doi":"10.1080/26895269.2025.2527828","DOIUrl":"https://doi.org/10.1080/26895269.2025.2527828","url":null,"abstract":"<p><strong>Background: </strong>Antiretroviral therapy (ART) adherence is essential for maintaining viral suppression and reducing HIV transmission risk. However, data on adherence rates among trans women living with HIV in India are scarce, hindering effective intervention efforts. Understanding multilevel syndemic factors, including harmful drinking, depressive symptoms, HIV, and trans women-related stigma, and access to gender-affirmative care, is crucial for improving HIV treatment outcomes in this population.</p><p><strong>Methods: </strong>Trans women living with HIV (N=150) in Mumbai and New Delhi, India, completed a one-time self-reported assessment of sociodemographic and psychosocial factors and ART adherence and provided recent viral load test results in the ART booklet. Latent class analysis (LCA) identified multilevel syndemic classes. Then, in logistic regression models, we assessed the relationship between syndemic classes and optimal ART adherence (defined as 90% or higher adherence as prescribed).</p><p><strong>Results: </strong>Optimal ART adherence (defined as 90% or higher adherence to prescribed doses) was reported by 63% of participants. Among those with suboptimal adherence (n=93), common barriers included lack of medication while traveling, forgetting, and alcohol use. The LCA identified two syndemic classes: Class 1, characterized by unidimensional stigma and moderate multilevel syndemic barriers, and Class 2, characterized by intersectional stigma and high multilevel syndemic barriers. In the bivariate analysis, participants in Class 2 had significantly lower odds of optimal ART adherence [OR: 0.27 (95% CI: 0.11 - 0.61), p = 0.003]. After controlling for potential confounders (i.e., city, monthly income, stable housing, and history of sex work), participants in Class 2 still had significantly lower odds of optimal ART adherence [aOR: 0.26 (95% CI: 0.09 - 0.64), p = 0.009].</p><p><strong>Conclusion: </strong>Findings highlight substantial disparities in ART adherence among trans women living with HIV in India, driven by intersectional stigma and multilevel syndemic barriers. Addressing these factors, particularly HIV and trans women-related stigma, is critical for improving ART adherence and HIV treatment outcomes in this population.</p>","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":" ","pages":""},"PeriodicalIF":14.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Call to Action: Advancing Research, Practice, and Policy for Middle Aged and Older Transgender and Nonbinary Communities.","authors":"Jamison Green, Jude Patton, Danit Ariel, John C Capozuca, Max Fuhrmann, Ames Simmons, Ethan C Cicero","doi":"10.1080/26895269.2025.2522244","DOIUrl":"10.1080/26895269.2025.2522244","url":null,"abstract":"","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":" ","pages":""},"PeriodicalIF":14.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12376073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current directions in research on patient experiences of metoidioplasty and phalloplasty.","authors":"Elijah R Castle, John E Castle, Leo L Rutherford","doi":"10.1080/26895269.2025.2521607","DOIUrl":"https://doi.org/10.1080/26895269.2025.2521607","url":null,"abstract":"","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":"26 4","pages":"951-954"},"PeriodicalIF":14.8,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12573541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Notice of duplicate publication: Fertility counseling guide for transgender and gender diverse people.","authors":"","doi":"10.1080/26895269.2025.2510136","DOIUrl":"10.1080/26895269.2025.2510136","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1080/26895269.2023.2257062.].</p>","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":"26 3","pages":"949"},"PeriodicalIF":14.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12312136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aggression changes during masculinizing and feminizing gender-affirming hormone therapy (GAHT) - A prospective clinical study.","authors":"Tine Taulbjerg Kristensen, Louise Lehmann Christensen, Ole Skov, Camilla Viola Buskbjerg Palm, Guy T'Sjoen, Marianne Skovsager Andersen, Dorte Glintborg, Kirsten K Roessler","doi":"10.1080/26895269.2025.2503222","DOIUrl":"10.1080/26895269.2025.2503222","url":null,"abstract":"<p><strong>Introduction: </strong>Testosterone and aggression have been positively associated, but it remains unclear whether gender-affirming hormone therapy (GAHT)-induced testosterone changes affect aggression in transgender persons. This study investigates aggression changes and associations between aggression and testosterone, depression, and anxiety during the first year of GAHT.</p><p><strong>Methods: </strong>Alternative-Short-Aggression-Questionnaire scores were assessed in transmasculine and transfeminine adults at baseline, six weeks, and one year post-GAHT initiation. Cisgender men and women were the comparison groups. Linear mixed effect models evaluated aggression score changes and group-differences, including effects of testosterone, depression, and anxiety, controlling for age and education.</p><p><strong>Results: </strong>Baseline data included 50 transmasculine (median age = 22 years), 62 transfeminine (median age = 24 years), 176 cisgender men (median age = 31 years), and 470 cisgender women (median age = 25 years). Seventy-one percent of transgender participants completed all follow-ups. Total and verbal aggression scores decreased after one year across transmasculine and transfeminine persons (mean difference (MD) = -1.6, <i>p</i> = .018 and MD = -0.8, <i>p</i> = .004), with no changes in other aggression dimensions. At baseline, transmasculine participants showed higher total aggression (MD = 3.4, <i>p</i> = .009) and anger (MD = 1.8, <i>p</i> < .001) scores than transfeminine persons. Transmasculine (MD = 3.3, <i>p</i> = .015) and transfeminine (MD = 6.5, <i>p</i> = <.001) persons had lower total aggression scores than cisgender men. Testosterone was not associated with aggression, whereas anxiety was significantly positively associated with aggression scores.</p><p><strong>Discussion: </strong>There was no GAHT-induced increased aggression in transmasculine persons. Total aggression scores decreased after one year across GAHT-types. Transgender aggression scores were significantly lower than cisgender men, indicating no risk of pathological aggression in the transgender population. Limitations included participant numbers and self-report measures.</p>","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":"27 2","pages":"1020-1032"},"PeriodicalIF":14.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13015110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"QT interval changes in transgender/gender diverse adolescents receiving gonadotropin-releasing hormone agonist and gender-affirming hormonal treatment.","authors":"Hussein Zaitoon, Livia Kapusta, Galit Israeli, Anat Segev-Becker, Gil Beer, Alexander Lowenthal, Gili Yaeger Yarom, Asaf Oren, Liat Perl","doi":"10.1080/26895269.2025.2503219","DOIUrl":"10.1080/26895269.2025.2503219","url":null,"abstract":"<p><p><b><i>Background</i></b> : Hormones play a significant role in modulating cardiac electrophysiology. Gonadotropin-releasing hormone agonists (GnRHa) and gender-affirming hormonal treatment (GAHT) may impact QTc intervals, which could have clinical implications.</p><p><strong>Aim: </strong>To evaluate QTc interval changes in transgender/gender-diverse (TGD) adolescents undergoing GnRHa and GAHT.</p><p><strong>Methods: </strong>This prospective study included 39 TGD adolescents (20 females), mean age 15.6 ± 1.4 years, Tanner stage 4-5. QTc intervals were measured before and after GnRHa treatment and following GAHT initiation.</p><p><strong>Results: </strong>The mean QTc increased significantly from 382.4 ± 16.2 ms at baseline to 402.9 ± 20.1 ms after GnRHa treatment (<i>p</i> = .019) and remained prolonged at 402.8 ± 19.6 ms after estrogen addition (<i>p</i> = .988) in 10 TGD females, with an overall significant change across all treatment phases (<i>p</i> = .020). The mean QTc increased from 371.6 ± 15.4 ms to 380.8 ± 13.5 ms (<i>p</i> = .180) in 10 TGD females who initiated combined GnRHa and estrogen. Pooling both TGD female groups, mean QTc increased significantly from 377.0 ± 16.3 ms to 391.8 ± 19.9 ms after GnRHa and estrogen (<i>p</i> = .014). The mean QTc increased from 386.3 ± 15.5 ms at baseline to 398.8 ± 24.1 ms after GnRHa treatment (<i>p</i> = .178) and decreased significantly to 377.7 ± 18.1 ms after the addition of testosterone (<i>p</i> = .009) in 6 TGD males, with an overall significant change across all treatment phases (<i>p</i> = .010). The mean QTc decreased from 395 ± 20.3 ms to 385.2 ± 19.8 ms (<i>p</i> = .139) in 13-TGD males who initiated combined GnRHa and testosterone. Pooling both TGD male groups, mean QTc decreased significantly from 392.4 ± 19.0 ms to 382.8 ± 19.1 ms after GnRHa and testosterone (<i>p</i> = .044). Two participants, prescribed psychiatric medications exhibited a borderline/short QTc after adding testosterone. No arrhythmias were observed.</p><p><strong>Discussion and conclusion: </strong>QTc prolongation was observed in TGD female adolescents after the initiation of GnRHa, while TGD males showed a decrease in QTc following testosterone administration. Further studies on the clinical implications of QT interval changes in this population are warranted.</p>","PeriodicalId":48480,"journal":{"name":"International Journal of Transgender Health","volume":"27 2","pages":"1033-1044"},"PeriodicalIF":14.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13015028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}