All Life最新文献_第6页

Prunetin alleviates dextran sulfate sodium-induced colitis via the regulation of inflammatory response based on network pharmacology and experimental evidence 基于网络药理学和实验证据的Prunetin通过调节炎症反应减轻葡聚糖硫酸钠诱导的结肠炎

IF 1.2 4区综合性期刊

All Life Pub Date : 2023-01-23 DOI: 10.1080/26895293.2022.2164359

L. Fan, Jing-ling Shi, Xiaobo Yang

引用次数: 0

QPromoters: sequence based prediction of promoter strength in Saccharomyces cerevisiae qpromoter:基于序列的酿酒酵母启动子强度预测

4区综合性期刊

All Life Pub Date : 2023-01-20 DOI: 10.1080/26895293.2023.2168304

Devang Haresh Liya, Mirudula Elanchezhian, Mukulika Pahari, Nithishwer Mouroug Anand, Shivani Suresh, Nivedha Balaji, Ashwin Kumar Jainarayanan

{"title":"QPromoters: sequence based prediction of promoter strength in <i>Saccharomyces cerevisiae</i>","authors":"Devang Haresh Liya, Mirudula Elanchezhian, Mukulika Pahari, Nithishwer Mouroug Anand, Shivani Suresh, Nivedha Balaji, Ashwin Kumar Jainarayanan","doi":"10.1080/26895293.2023.2168304","DOIUrl":"https://doi.org/10.1080/26895293.2023.2168304","url":null,"abstract":"Promoters play a key role in influencing transcriptional regulation for fine-tuning the expression of genes. Heterologous promoter engineering has been a widely used concept to control the level of transcription in all model organisms. The strength of a promoter is mainly determined by its nucleotide composition. Many promoter libraries have been curated, but few have attempted to develop theoretical methods to predict the strength of promoters from their nucleotide sequence. Such theoretical methods are not only valuable in the design of promoters with specified strength but are also meaningful in understanding the mechanistic role of promoters in transcriptional regulation. In this study, we present a theoretical model to describe the relationship between promoter strength and nucleotide sequence in Saccharomyces cerevisiae. We infer from our analysis that the −49–10 sequence with respect to the Transcription Start Site represents the minimal region that can be used to predict promoter strength. https://qpromoters.com/ and a standalone tool https://github.com/DevangLiya/QPromoters to quickly quantify the strength of Saccharomyces cerevisiae promoters.","PeriodicalId":48478,"journal":{"name":"All Life","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134969138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acoustic and temperature signals generated by subterranean termite infestation: its characteristics and implementations 地下白蚁侵袭产生的声温信号及其特征与实现

IF 1.2 4区综合性期刊

All Life Pub Date : 2023-01-19 DOI: 10.1080/26895293.2023.2167866

M. A. Nanda, K. Seminar, A. Maddu, D. Nandika

引用次数: 0

Use of the concept ‘environmentally relevant level’ in linking the results of pesticide toxicity studies to public health outcomes 在将农药毒性研究结果与公共卫生结果联系起来时，使用"环境相关水平"的概念

IF 1.2 4区综合性期刊

All Life Pub Date : 2023-01-19 DOI: 10.1080/26895293.2023.2167872

R. Mesnage, C. Benbrook

引用次数: 2

Sleep as a likely immunomodulation agent: novel approach in the treatment of COVID-19 睡眠作为一种可能的免疫调节剂:治疗COVID-19的新方法

IF 1.2 4区综合性期刊

All Life Pub Date : 2023-01-19 DOI: 10.1080/26895293.2023.2166131

K. Hassanpour, H. Esmaeili Gouvarchin Ghaleh, M. Khafaei, A. Hosseini, Gholamreaza Farnoosh, T. Badri, Mostafa Akbariqomi

{"title":"Sleep as a likely immunomodulation agent: novel approach in the treatment of COVID-19","authors":"K. Hassanpour, H. Esmaeili Gouvarchin Ghaleh, M. Khafaei, A. Hosseini, Gholamreaza Farnoosh, T. Badri, Mostafa Akbariqomi","doi":"10.1080/26895293.2023.2166131","DOIUrl":"https://doi.org/10.1080/26895293.2023.2166131","url":null,"abstract":"The potential advantages of sleep concerning suppressing cytokine storms and inflammation in coronavirus disease 2019 (COVID-19) based on its immunopathogenesis are summarized in the current study. COVID-19 as a global pandemic in the past months has afflicted many people. Clinical properties, pathology, and the pathogenesis of acute respiratory disorder caused by coronaviruses or other pathogens are evidence implying the probable contribution of oxidation, excessive inflammation, and excessive immune response, particularly cytokine storm, to the pathology of COVID-19. According to findings by experimental and clinical research on animals and in humans, sleep loss impairs immune function. Sleep loss strongly influences peripheral levels of the immune response's inflammatory mediators, which is accomplished by the generation of various hormones and mediators during sleep. There are a large number of studies supporting the presence of reciprocal regulation between low-intensity inflammatory response and sleep. By improving sleep quality and at the same time adjusting the circadian rhythm, it may be possible to prevent infections and boost immunity. As a result, sufficient (or even more) sleep duration may lower susceptibility to COVID-19 infection as well as increase antibody levels. © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.","PeriodicalId":48478,"journal":{"name":"All Life","volume":"21 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73987691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pregnancy-associated breast cancer (PABC) in young women: a matched case-control study 年轻女性妊娠相关乳腺癌(PABC):一项匹配病例对照研究

IF 1.2 4区综合性期刊

All Life Pub Date : 2023-01-19 DOI: 10.1080/26895293.2023.2167867

yanshou zhang, Zhifen Yang, Chunyang Wang, Lijia Du, Yingru Liu

引用次数: 1

Inhibition or promotion, the potential role of arginine metabolism in immunotherapy for colorectal cancer 抑制或促进精氨酸代谢在结直肠癌免疫治疗中的潜在作用

IF 1.2 4区综合性期刊

All Life Pub Date : 2023-01-17 DOI: 10.1080/26895293.2022.2163306

Chengyang Chen, Xia Jiang, Zengren Zhao

引用次数: 1

Metagenomic analysis of Tongxie Yaofang therapy for rat models of ulcerative colitis with liver depression and spleen deficiency syndrome 痛泻药方治疗溃疡性结肠炎肝郁脾虚证大鼠模型的宏基因组分析