Research in Autism Spectrum Disorders最新文献

{"title":"Virtual reality educational scenarios for students with ASD: Instruments validation and design of STEM programmatic contents","authors":"Rui Manuel Silva ,&nbsp;Paulo Martins ,&nbsp;Tânia Rocha","doi":"10.1016/j.rasd.2024.102521","DOIUrl":"10.1016/j.rasd.2024.102521","url":null,"abstract":"<div><h3>Background</h3><div>Virtual Reality (VR) is making education more engaging and accessible, especially for students with Autism Spectrum Disorders (ASD), promoting inclusion and the development of STEM skills in innovative ways. The literature still reveals a significant gap in terms of appropriate educational resources adapted to the specific needs of these students, resulting in difficulties in their inclusion. With the growing need for inclusive approaches in education, it is essential to find solutions to support these students. The aim of this study is to validate the data collection methodology that will enable the development of Virtual Learning Environments with STEM content for students with ASD.</div></div><div><h3>Methods</h3><div>The Design Science Research (DSR) methodology was used to develop a VR artefact for students with ASD. In addition, the Delphi method was applied in the expert involvement phase, which will contribute to the validation of the artefact's specific requirements. Both will allow for an inclusive and distinctive approach to the development of an artefact, with the aim of offering an innovative educational experience, meeting the varied needs and learning styles of students with ASD, optimising the effectiveness of the proposed VLE.</div></div><div><h3>Results</h3><div>The results show a strong acceptance among experts, highlighting the potential positive impact of this approach, although there are aspects to be improved to ensure a more comprehensive and effective approach.</div></div><div><h3>Conclusions</h3><div>This study highlights the successful validation of an innovative virtual reality programme for students with ASD, highlighting the importance of interdisciplinary collaboration and the strong contribution to the advancement of inclusive education.</div></div>","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102521"},"PeriodicalIF":2.2,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142747061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The BTBR T+ Itpr3tf/J mouse strain as a model to study the genetic, immune, and metabolic origins of neurodevelopmental disorders","authors":"MP Viscomi,&nbsp;J. Czyrska,&nbsp;D. Winiarczyk,&nbsp;MM Ziętek,&nbsp;S. Sampino","doi":"10.1016/j.rasd.2024.102526","DOIUrl":"10.1016/j.rasd.2024.102526","url":null,"abstract":"<div><div>The BTBR T⁺ Itpr3^tf/J (BTBR) mouse strain manifests a peculiar behavioral phenotype that mirrors the core symptomatology of autism spectrum disorders, including alterations in social-communicative behavioral domains, and the presence of repetitive/stereotyped behaviors. Concurrent immune and metabolic imbalances characterize the BTBR phenotype and are exacerbated by specific gene mutations, resulting in severe multi-organs imbalances that recapitulate the symptoms of human autoimmune and metabolic disorders. The present review aims to retrace and summarize state-of-the-art regarding the genetic, immune, and metabolic features of the BTBR strain and address its potential use as a valid model to study the multi-system etiology and pathogenesis of neurodevelopmental disorders.</div></div>","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102526"},"PeriodicalIF":2.2,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142747062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief report: Social relationships among autistic young adults with varying cognitive abilities","authors":"Dena Gohari,&nbsp;Jamie Park,&nbsp;Hillary Schiltz,&nbsp;Catherine Lord","doi":"10.1016/j.rasd.2024.102524","DOIUrl":"10.1016/j.rasd.2024.102524","url":null,"abstract":"<div><h3>Background</h3><div>Autism is characterized by social difficulties, yet many autistic people value and desire social relationships. Given the limited research on autism in adulthood, particularly among those with lower cognitive ability, this study aimed 1) to compare self- vs informant-report of social relationships (acquaintances, friendships, and interpersonal difficulties) and 2) to compare social relationships, between more cognitively able (MCA) and less cognitively able (LCA) autistic young adults.</div></div><div><h3>Method</h3><div>Participants included 101 autistic young adults (M_<em>age</em>=25.90; SD=1.41; 82.0 % male; 79.8 % White) and their informants. Participants were interviewed, and the Interpersonal Difficulties and Social Relationships sections of the Social and Emotional Functioning Interview (SEF) were analyzed. Participants were classified as MCA (IQ≥70) or LCA (IQ&lt;70).</div></div><div><h3>Results</h3><div>For the MCA sample, informant and self-report SEF scores were all positively correlated and did not have significantly different median values. Weaker and non-significant associations emerged for social contexts outside of the home (e.g., at work) and more abstract concepts (e.g., quality of relationships). Although cognitive ability impacted the extreme SEF scores (e.g., having self-initiated reciprocal friendships), many social difficulties were shared by LCA and MCA young adults, according to informant reports.</div></div><div><h3>Conclusions</h3><div>This study is one of few on social relationships and autism to focus on adulthood and include LCA young adults. Results indicate that informant-report provides useful information on more concrete aspects of social relationships in this population. Many autistic young adults, and LCA young adults in particular, may benefit from additional social supports, yet it is also essential to collaboratively consider what types of social experiences and relationships are desired and feasible for each person. More research and intervention tailored to LCA autistic young adults are needed.</div></div>","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102524"},"PeriodicalIF":2.2,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142747200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Which emerging autism features at 12 months of age are associated with later parent-child interaction?","authors":"Chengcheng Ke ,&nbsp;Lesley-Anne Carter ,&nbsp;Jonathan Green ,&nbsp;Andrew J.O. Whitehouse ,&nbsp;Kristelle Hudry ,&nbsp;Josephine Barbaro ,&nbsp;Cheryl Dissanayake ,&nbsp;Murray Maybery ,&nbsp;Slonims Vicky ,&nbsp;Leonie Segal ,&nbsp;Kandice Varcin ,&nbsp;Ming Wai Wan","doi":"10.1016/j.rasd.2024.102525","DOIUrl":"10.1016/j.rasd.2024.102525","url":null,"abstract":"<div><h3>Background</h3><div>Parent-child interactions (PCI) in infants with an elevated likelihood (EL) of autism start to diverge from other infants toward the end of the first year. This divergence is often attributed to emerging features of autism impacting infant social interactions in ways that become increasingly amplified. The aim was to identify which, if any, 12-month autism features were associated with later PCI qualities.</div></div><div><h3>Method</h3><div>Twelve-month-old infants (N = 103) with early autism features (3+ on the Social Attention and Communication Surveillance-Revised tool) were assessed on the Autism Observation Scale for Infants (AOSI) at 12 and 18 months, and on free play PCI using the Manchester Assessment of Caregiver-Infant Interaction at 18 months.</div></div><div><h3>Results</h3><div>AOSI autism features at 12-months were associated with 18-month PCI qualities, independent of 18-month autism features. Specifically, infants with emerging features in social attention areas later showed less attentiveness to parents and lower dyadic mutuality. By contrast, infants with emerging sensorimotor atypicality/delay later showed increased attentiveness to parents and lower negative affect, their parents were more sensitively responsive, and their interactions were more mutual. Emotional regulation scores had no significant association with later PCI.</div></div><div><h3>Conclusions</h3><div>The findings support the notion that PCI changes in EL infants are rooted in the transactional impact of early emerging autism-related features, which may have differential effects on PCI. Pending replication in a larger sample using a detailed measure of early autism features, the findings suggest that early autism features may amplify or elicit interactions.</div></div>","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102525"},"PeriodicalIF":2.2,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142722056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skill-based treatment for challenging behavior in autism spectrum disorder: A scoping review of treatment characteristics and outcomes","authors":"Kristin M. Hustyi ,&nbsp;Jesse J. Logue ,&nbsp;Scott S. Hall","doi":"10.1016/j.rasd.2024.102523","DOIUrl":"10.1016/j.rasd.2024.102523","url":null,"abstract":"<div><h3>Background</h3><div>Behavioral interventions based on the principles of applied behavior analysis (ABA) are considered the gold standard approach for treating challenging behaviors commonly exhibited by children with autism spectrum disorder (ASD). However, questions have arisen concerning the safety of implementing traditional ABA procedures for the treatment of challenging behavior in natural settings. Over the past decade, a treatment package known as skill-based treatment (SBT) has emerged that may allow challenging behaviors in this population to be addressed in a safe, efficient, and effective manner.</div></div><div><h3>Methods</h3><div>We reviewed and summarized studies utilizing SBT published in English between 2014 and September 2023 using PsychINFO and PubMed databases. Two independent reviewers screened citations for inclusion. Data abstraction was performed by one reviewer and verified by a second reviewer.</div></div><div><h3>Results</h3><div>Twenty-one studies (3 consecutive controlled case series and 18 utilizing single-case experimental designs) met the inclusion criteria describing SBT conducted with 87 individuals. The majority of individuals treated with SBT were autistic children with language levels varying from non-vocal to fully fluent. Treatments were implemented in a variety of settings at least 1–2 times per week, with treatment requiring a range of 4 - 48.5 h of clinician time. Rates of challenging behavior were reported to decrease by 98.2 % (range: 90–100 %) on average. Treatments were implemented via telehealth for 8 individuals (9.2%). Data concerning treatment maintenance was reported for just 7 individuals (8.1 %).</div></div><div><h3>Conclusions</h3><div>SBT is a potentially effective treatment procedure for challenging behavior that can be conducted in a variety of settings including the child’s home, school, and via telehealth. However, future research is needed to understand the long-term effectiveness of SBT. Randomized controlled trials of SBT are also necessary in order to study the safety and efficacy of this treatment approach.</div></div>","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102523"},"PeriodicalIF":2.2,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142747201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family experiences with supplemental social security income and legal guardianship for autistic adults: A mixed-methods study","authors":"Emily F. Ferguson ,&nbsp;Elaine B. Clarke ,&nbsp;Noa Schisterman ,&nbsp;Catherine Lord","doi":"10.1016/j.rasd.2024.102522","DOIUrl":"10.1016/j.rasd.2024.102522","url":null,"abstract":"<div><h3>Background</h3><div>Family interactions with the Supplemental Social Security Income (SSI) program and the decision to pursue legal guardianship are poorly understood in services research for autistic adults.</div></div><div><h3>Methods</h3><div>We conducted a mixed-methods study and incorporated quantitative survey data from 122 autistic adults in an existing longitudinal cohort with qualitative interviews with 12 autistic adults and/or legal guardians. We explored sociodemographic, developmental, and behavioral features associated with the likelihood of having SSI and a legal guardian at 25 years old. Spoken interviews were transcribed verbatim, and interviews were analyzed using a rapid qualitative analytic approach.</div></div><div><h3>Results</h3><div>There were quantitative differences in whether families were able to obtain SSI and guardianship based on intelligence quotient (IQ) scores, adaptive behavior, and autistic characteristics, but not by race, ethnicity, or maternal education. Qualitative data analysis revealed six themes that highlighted the challenges associated with obtaining and maintaining SSI, along with the complex, nuanced decisions associated with legal guardianship. Families noted many challenges in navigating these procedures and some potential benefits for each unique circumstance.</div></div><div><h3>Conclusions</h3><div>These findings offer new perspectives on experiences associated with pursuing SSI benefits and legal guardianship for autistic adults<strong>,</strong> including similarities and key differences in these procedures. Findings also provide suggestions for future research to improve coordination and supports for families throughout adulthood.</div></div>","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102522"},"PeriodicalIF":2.2,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142722051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on: Towards a neurodiversity-affirmative conceptualisation of psycho-education in the context of autism","authors":"Daniel Shepherd","doi":"10.1016/j.rasd.2024.102517","DOIUrl":"10.1016/j.rasd.2024.102517","url":null,"abstract":"","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102517"},"PeriodicalIF":2.2,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Child sleep onset latency mediates parental depression and noncompliance in autistic children","authors":"Melanie A. Stearns ,&nbsp;Braden Hayse ,&nbsp;Neetu Nair ,&nbsp;Micah Mazurek ,&nbsp;Ashley F. Curtis ,&nbsp;David Beversdorf ,&nbsp;Kristin Sohl ,&nbsp;Julie Muckerman ,&nbsp;Christina S. McCrae","doi":"10.1016/j.rasd.2024.102518","DOIUrl":"10.1016/j.rasd.2024.102518","url":null,"abstract":"<div><h3>Background</h3><div>Parents diagnosed with depression often report that their children have difficulty following rules and falling asleep. Parents with depression are less likely to be consistent or enforce bedtimes, resulting in the child having fewer bedtime rules and getting less sleep. Over time this may mean the child develops poor sleep habits and difficulty falling asleep. Although these relationships have yet to be studied in children diagnosed with Autism Spectrum Disorder (ASD), it is an important area given that approximately 80 % of autistic children have sleep difficulties.</div></div><div><h3>Methods</h3><div>The current study examined whether parent-reported child sleep onset latency (SOL) mediated the relationship between parental depression and child noncompliance. The sample (<em>N</em>=34) consisted of parents (82 % female) reporting on their children aged 6–12 (<em>M</em>=8.63, <em>SD</em> = 2.00; 76.5 % male). All children were diagnosed with ASD and had parent-reported sleep complaints. Measures included the Child Sleep Health Questionnaire (CSHQ), the Pediatric Symptom Checklist (PSC), and a question asking if the parent had been diagnosed with depression (yes/no).</div></div><div><h3>Results</h3><div>Greater parent-reported child SOL significantly mediated the relation between increased parental depression and greater noncompliance.</div></div><div><h3>Conclusions</h3><div>These results suggest that difficulty falling asleep may help to explain why children of parents who have depression are noncompliant.</div></div>","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102518"},"PeriodicalIF":2.2,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of age at first alcohol use among a US-based sample of autistic underage youth","authors":"Calliope Holingue ,&nbsp;Laura Graham Holmes ,&nbsp;Julia Cusano ,&nbsp;Emily F. Rothman","doi":"10.1016/j.rasd.2024.102520","DOIUrl":"10.1016/j.rasd.2024.102520","url":null,"abstract":"<div><h3>Background</h3><div>Recent research has identified risk factors for hazardous alcohol use among autistic individuals, but correlates of age at first alcohol use are unclear.</div></div><div><h3>Methods</h3><div>This study analyzed 49 U.S.-based autistic youth (ages 16–20) who had ever consumed alcohol. Participants were categorized as being less than 16 years old (n=28) or 16 years or older (n=21) at first alcohol use. The analysis aimed to descriptively compare youth with younger versus older age at first alcohol use.</div></div><div><h3>Results</h3><div>Younger age at first alcohol use was associated with hazardous alcohol use, higher levels of anxiety, and lower masking of autistic traits</div></div><div><h3>Conclusions</h3><div>These findings demonstrate that autistic youth are at risk for underage alcohol use. More research is needed on alcohol and substance use in this population to develop tailored prevention and intervention programs.</div></div>","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102520"},"PeriodicalIF":2.2,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the general psychopathology factor in autistic youth","authors":"Hannah Muriel Robb Burrows ,&nbsp;Brianne Derby ,&nbsp;Laura de la Roche ,&nbsp;Melissa Susko ,&nbsp;Rob Nicolson ,&nbsp;Stelios Georgiades ,&nbsp;Jessica Jones ,&nbsp;Evdokia Anagnostou ,&nbsp;Elizabeth Kelley","doi":"10.1016/j.rasd.2024.102519","DOIUrl":"10.1016/j.rasd.2024.102519","url":null,"abstract":"<div><h3>Background</h3><div>Autistic youth are at higher risk of presenting with co-occurring internalizing (I) (i.e., anxiety and depression) and externalizing (E) (i.e., aggression and impulsivity) disorders (Bauminger et al., 2010). The <em>Child Behavior Checklist for ages 6–18</em> (CBCL/6-18; Achenbach &amp; Rescorla, 2001) is a measure of I-E disorders and symptoms in autistic and neurotypical youth, providing norm-referenced subscales as factors for each form of psychopathology. The general psychopathology or “<em>p</em>” factor may provide a better measure of co-occurring disorders in autism as it has not been evaluated in this population contextually to date. The <em>p</em> factor proposes that psychopathological disorders come from the same etiological factor, implying that we can measure all I-E disorders as indicators of <em>p</em>.</div></div><div><h3>Method</h3><div>Using archival data from the <em>Province of Ontario Neurodevelopmental Disorders</em> (POND) <em>Network</em>, (<em>N</em> = 782) autistic youths’ raw scores from the CBCL/6-18 were analyzed using two confirmatory factor analyses (CFAs): an I-E CFA and a <em>p</em> factor CFA. An exploratory factor analysis (EFA) was also conducted to determine the best-fitting factor structure.</div></div><div><h3>Results</h3><div>A chi-square difference test compared each CFA to find the best model fit. Results reported each model as individually significant, however, based on recommendations from Hoyle and Panter (1995), neither model had an acceptable fit.</div></div><div><h3>Conclusions</h3><div>Given that neither the <em>p</em> factor nor the internalizing/externalizing factor models had appropriate fit, it is recommended that future research investigate whether the CBCL/6–18 is the most appropriate measure for assessing co-occurring symptoms in autistic youth. The results of the EFA also suggest that the CBCL may not be the most appropriate measure for autistic youth.</div></div>","PeriodicalId":48255,"journal":{"name":"Research in Autism Spectrum Disorders","volume":"119 ","pages":"Article 102519"},"PeriodicalIF":2.2,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}