Vestnik medicinskogo instituta "REAVIZ": reabilitaciâ, vrač i zdorovʹe最新文献

{"title":"Morphological characteristics and diagnostic criteria of traditional serrated adenoma","authors":"A. S. Tertychnyy, N. V. Pachuashvili, P. V. Pavlov, A. P. Kiryukhin, A. A. Fedorenko, N. S. Marenich","doi":"10.20340/vmi-rvz.2023.5.morph.1","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.5.morph.1","url":null,"abstract":"Traditional serrated adenomas (TSAs) are extremely rare polyps from the group of serrated polyps of the colon. TSAs is no more than 5 % of all colon polyps. A relatively small number of studies have been devoted to this histological variant, at the same time, some aspects of the morphological diagnosis of TSA still remain undisclosed. Purpose: to conduct a clinical and morphological analysis of cases of TSAs. Materials and methods . The study included 57 cases of TSAs diagnosed in the period from 2021 to 2023. In the cases detected during this period, the results of histological and endoscopic studies were analyzed. Results . The age of patients ranged from 44 to 78 years and averaged 61.7 years. The ratio of men and women is 1:1.8. Most TSAs were found in the rectum (n = 28) and sigmoid colon (n = 20). In 8 cases, the tumor was localized in the descending part and the splenic flexure of the colon. In 1 observation, a tumor was found in the cecum. The sizes of the polyps ranged from 0.5 cm to 3.5 cm. In 22 cases, the composition of the polyp included tubulovillous adenomas (16 cases) and hyperplastic polyps (6 cases) in addition to TSAs. In 5 cases, foci of highly differentiated adenocarcinoma were detected in the TSAs material. Conclusion . TSAs has characteristic morphological features with a serrated exophytic growth pattern, cytoplasmic eosinophilia and the presence of ectopic crypts. Due to the difficulties of morphological diagnosis, TSAs in some cases remains undiagnosed. At the same time, due to the increased malignant potential, TSAs requires special vigilance on the part of pathologists and clinicians.","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135621579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effectiveness of allogeneic tendon graft sterilization with supercritical carbon dioxide","authors":"A. A. Budaev, N. V. Borovkova, A. M. Fayn, A. Yu. Nikolaev, M. S. Makarov, M. V. Storozheva, K. I. Skuratovskaya, A. Yu. Vaza, I. V. Fomicheva, T. V. Chernen'kaya, A. А. Kanibolotskiy","doi":"10.20340/vmi-rvz.2023.4.tx.2","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.4.tx.2","url":null,"abstract":"Structural and functional properties of the human tendon tissue complicate process of tendon-based grafts preserving. In the process of preservation, it is necessary to maintain mechanical and functional parameters of the tendon tissue as well as to provide sterility and biological safety of the graft. One could conclude effectiveness of techniques, combining tendon conservation at low temperatures and sterilization with the supercritical carbon dioxide. Aim of work : to find optimal conditions for allogeneic tendon grafts sterilization with supercritical carbon dioxide. Materials and methods . Allogeneic tendons were prepared from the tissue donors, following the rules of asepsis and antisepsis. After quarantine and confirmation of the absence of blood-borne infections the tendon grafts were divided into 3 groups: in the control group the tendons were not subjected to cryopreservation and sterilization procedures; in 2 experimental groups tendons were treated with a cryoprotector 10 % dimethyl sulfoxide (DMSO) solution and sterilized with supercritical carbon dioxide with slow gas discharge (group 2) or with fast gas discharge (group 3); the duration of sterilization in both groups varied from 1 to 12 hours. The toxicity of the grafts was assessed in human mesenchymal multipotent stromal cells (MMSC) culture on the 3rd and 7th days. The sterility of the grafts was confirmed on the 7th and 14th day by bacteriological culture on thioglycol medium and Saburo broth. Mechanical tests were performed on testing machine LLOYD Instruments LR5K Plus with the tensile speed 5 mm/min. Results. Histological analysis showed, that in the group with slow gas discharge collagen fibers retained their integrity and topography and contained only local minor tears; in all terms of treatment, the tendon grafts were sterile and nontoxic. On the contrary, in the group with fast gas discharge there was marked damage of the collagen fibers and growth of bacterial and fungal flora was observed in the culture. The grafts of the control group and the group, where sterilization with supercritical carbon dioxide was performed with slow gas discharge for 1-12 hours, were used to evaluate mechanical characteristics. In the preserved tendons the stiffness and ultimate strain did not significantly differ from the similar values in the control (p > 0.05), on the contrary, the level of ultimate strain in all experimental specimens was significantly reduced by 1.5-2.1 times comparing to the control. Young's modulus and load at rupture in the control grafts and grafts, sterilized for 1 hour, had similar values, whereas in grafts, sterilized from 3 to 12 hours, these parameters were 1.4-2.1 times lower (p < 0.05). Conclusions. The suggested technique of tendon preservation, using cryoprotector DMSO and sterilization with the supercritical carbon dioxide, allows to obtain sterile and non-toxic grafts. The structure of cells and fibers of the preserved tendons did not significantly distu","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135307687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of venous thromboembolic complications in patients with diabetes mellitus and COVID-19","authors":"D. V. Abramov, A. V. Smol'kina","doi":"10.20340/vmi-rvz.2023.5.clin.10","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.5.clin.10","url":null,"abstract":"The article assesses concomitant diabetes mellitus as a risk factor for venous thromboembolic complications in patients with covid-19 in hospital settings. We analyzed 123 case histories of patients hospitalized for new coronavirus infection in the first wave of COVID-19. The results showed that diabetes mellitus was not an independent risk factor for venous thromboembolic complications in patients with COVID-19.","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"107 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135492339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological effects of using a high-protein, low-carbohydrate diet of pregnant and lactating female rats on the development of their offspring","authors":"A. A. Makarcheva, I. D. Romanova, E. M. Inyushkina, R. A. Zaynulin","doi":"10.20340/vmi-rvz.2023.5.phys.4","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.5.phys.4","url":null,"abstract":"In the modern world, the nature of human nutrition is becoming more relevant. This is due to the spread of diseases such as diabetes mellitus, cardiovascular diseases and metabolic disorders. The health of a person and his offspring comes to the fore. In this regard, high-protein, low-carbohydrate diets are becoming popular at the moment. The aim of the study was to identify the effect of a high-protein, low-carbohydrate diet of pregnant and lactating female rats on the development of their offspring. Object and methods . The experiment was carried out on the offspring of female rats. The female rats of the control group received normal nutrition, and for the experimental group a special high-protein, low-carbohydrate diet was compiled, which was maintained throughout pregnancy and in the first week after delivery. As a result of the study, it was revealed that a diet with an increased protein content has a beneficial effect on the development of baby rats in delayed terms: they have a more pronounced weight gain, increased research activity and are less prone to anxiety.","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135492101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human’s levator ani muscle &amp; rectum syntopic relations in the light of classic and digital morphologic methods’ data","authors":"S. N. Chemidronov, A. V. Kolsanov, G. N. Suvorova","doi":"10.20340/vmi-rvz.2023.4.morph.1","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.4.morph.1","url":null,"abstract":"Recently, one of the most pressing issues of modern medicine is pelvic floor dysfunction, which includes pelvic organ prolapse, urinary and fecal incontinence []. The leading role in maintaining the pelvic organs is assigned to levator ani muscle. The study of attachment features of muscle to pelvis, rectum will clarify the pathogenesis of pelvic floor insufficiency and development of incontinence symptoms and pelvic organs prolapse. The use of classical morphological and innovation technologies of «Autoplan» hardware and software complex using MRI data made it possible to identify morphologically denser and sparse zones of the wall of the distal rectum, directly related to the attachment of levator ani muscle fibers to it.","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135492665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical justification of the use of a three-part two-support bridge prosthesis","authors":"I. O. Buentsov, A. M. Nesterov","doi":"10.20340/vmi-rvz.2023.5.dent.1","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.5.dent.1","url":null,"abstract":"Describes the relevance of the use of fixed orthopedic structures in prosthetics of patients with partial absence of teeth. Clinical features of orthopedic rehabilitation of a patient with this pathology are revealed. The results of a computational experiment on choosing the optimal sizes of the supporting parts of a three-part bridge prosthesis are presented. The technology of manufacturing a bridge prosthesis is described and the nearest clinical results of treatment of this disease are given.","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"694 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135492102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The direction of increasing effectiveness of the treatment of periprosthetic joint infection","authors":"A. V. Shabunin, S. E. Arakelov, V. E. Dubrov, R. Yu. Maer, V. N. Obolenskiy, O. D. Podkosov, P. Sh. Leval', N. A. Nabatchikov","doi":"10.20340/vmi-rvz.2023.5.clin.4","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.5.clin.4","url":null,"abstract":"Introduction : in the world orthopaedic practice, attention is increasingly paid to surgical interventions that improve the patient’s quality of life. One of these interventions is joint arthroplasty. The most common reason for this operation is osteoarthritis. It is known that coxarthrosis and gonarthrosis have a a high incidence in the world and there is a dynamic increase in the amount data pathologies. However, behind all the advantages of joint arthroplasty here is most formidable complication – periprosthetic infection, which can be fatal for the patient. According to opinion of domestic and foreign experts, for a successful treatment of patients with this complication, intervention is needed by specialists of a narrow profile in combination with a multidisciplinary approach, however patient routing an unresolved problem to this day. The purpose of the work : to propose a model for routing patients with periprosthetic joint infection in Moscow. Results . As a result of the work carried out it was found that the main problem of routing patients with periprosthetic joint infection in Moscow is the stage and timing of the disease. Often the patient with lat periprosthetin infection is hospitalized in a hospital in a city that has a department of purulent surgery, but the specialists of the department have not the necessary equipment and skills to provide effective and qualified care as a result of which patient wastes time that could be spent more rationally. Conclusion . For more efficient routing of patients with periprosthetic joint infection in Moscow it is necessary to create specialized centres for the treatment of advanced perprosthetic infection. In cases of early periprosthetic infection the patient can undergo sanitizing surgical mixing in the conditions of the department of purulent surgery of any hospital in Moscow.","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135492338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current methods of modeling depression in animals and approaches to the study of their efficiency in biomedical research (review of the problem)","authors":"D. S. Gromova, N. R. Popova, O. N. Pavlova, Yu. V. Myakisheva, S. I. Pavlenko","doi":"10.20340/vmi-rvz.2023.5.phys.2","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.5.phys.2","url":null,"abstract":"Depressive disorders are one of the leading problems of modern health care. Their prevalence in the world ranges from 4.4 to 20 % of the population, and in Russia the incidence of depression reaches 20 %. The study of depressive disorders is relevant not only from the point of view of psychiatry and behavioral therapy, but also occupies a leading place in neurological practice, since more than a quarter of the population with chronic neurological diseases suffer from depression. Currently, most basic biomedical research on depressive disorders is carried out using laboratory animals. However, the protocols for experimental modeling and analysis of behavioral patterns are very diverse, which creates certain difficulties in planning research. This review is aimed at describing, analyzing, comparing and systematizing possible approaches to creating experimental models of depression in animals, and also contains criteria for model validation and a description of behavioral tests to assess anxiety-depressive disorders.","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135504287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational risk factors impact on the reproductive system of female flight attendants in civil aviation (literature review)","authors":"A. R. Dmitrenko, Yu. L. Timoshkova, T. E. Kurmanbaev","doi":"10.20340/vmi-rvz.2023.5.clin.8","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.5.clin.8","url":null,"abstract":"The review article discusses the issues of studying occupational factors on the reproductive health of female flight attendants. The purpose of the study is to identify a correlation between reproductive health disorders of flight attendants and flight factors. Literature data from the Fundamental Library of the Military Medical Academy named after S.M. Kirov, online sci-hub library «CyberLeninka», e-library and PubMed was analyzed and systematized. Such professional factors as: ionizing radiation, physical stress in flight, work in a plantigrade position, disturbance of the regime of working, resting time and eating patterns, constant change of climatic zones, desynchronosis, – were identified. An analysis of the literature has shown that a number of issues related to flight factors and women's health remain poorly understood. It is advisable to study in detail the flight factors: vibration, noise, acceleration, hypoxia, pressure drops, and their impact on the reproductive system of female specialists working in aviation.","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135504286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coecum mobile. Literature review and clinical observation","authors":"Y. A. Isaev, A. N. Sergeev, A. M. Morozov, M. S. Shestakov","doi":"10.20340/vmi-rvz.2023.5.case.2","DOIUrl":"https://doi.org/10.20340/vmi-rvz.2023.5.case.2","url":null,"abstract":"Relevance . Anomalies of the position and attachment of the colon in the abdominal cavity includes a large number of options. In some cases, the pathology is not limited exclusively to the mobility of the cecum, but is combined with a violation of the fixation of the ascending colon, the absence of attachment of the hepatic and splenic angles, omission of the right half of the colon or total colonoptosis. Results . There is surgical pathology associated with abnormal position and attachment of the circumferential intestine in the abdomen and a case of abnormal position dependency and an anomaly of the attachment of the right side of the circumferential intestine, depending on body type, which have certain clinical manifestations. Clinical manifestations of this pathology, methods of diagnosis and treatment with favorable results are described in the article. Also own surgical treatment methods depending on the anatomical variant of the pathology are presented in the article. Conclusion . The anatomical restoration of the correct position of the intestine in the abdominal cavity is operative. The proposed operation is performed taking into account the anomaly variant.","PeriodicalId":481396,"journal":{"name":"Vestnik medicinskogo instituta \"REAVIZ\": reabilitaciâ, vrač i zdorovʹe","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135288207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}