Fitsum A. Gemechu , Michael A. Negussie , Messay Gebrekidan , Biruk Zenebe Bekele , Elsa Wolde Mamo , Shimelis Nigussie Gebremariam
{"title":"A large type IV-A choledochal cyst mimicking hydatid cyst of the liver: A case report","authors":"Fitsum A. Gemechu , Michael A. Negussie , Messay Gebrekidan , Biruk Zenebe Bekele , Elsa Wolde Mamo , Shimelis Nigussie Gebremariam","doi":"10.1016/j.ijscr.2025.110898","DOIUrl":"10.1016/j.ijscr.2025.110898","url":null,"abstract":"<div><h3>Introduction</h3><div>Choledochal cysts are rare congenital anomalies of the bile ducts, with adult presentations being uncommon. This case is notable for its atypical presentation in a young adult, mimicking a hydatid cyst in a region where echinococcosis is endemic.</div></div><div><h3>Case presentation</h3><div>A 22-year-old female presented with a 3-month history of progressive jaundice, accompanied by 5 months of epigastric and right upper quadrant pain, dark urine, pale stools, pruritus, and significant weight loss. She reported a prior admission for cholangitis, treated with antibiotics. Examination revealed stable vital signs, icteric sclerae, right upper quadrant tenderness, and scratch marks on the skin. Laboratory investigations showed elevated liver enzymes and hyperbilirubinemia (total bilirubin = 26 mg/dL, direct bilirubin = 20.5 mg/dL). Initial imaging studies, including ultrasound and CT, suggested a hydatid cyst of the liver. However, MRCP revealed dilated intrahepatic and extrahepatic bile ducts, consistent with a Type IV-A choledochal cyst. The patient underwent cholecystectomy, extrahepatic bile duct excision, and Roux-en-Y cysto-jejunostomy. Histopathological analysis confirmed the diagnosis without evidence of malignancy. She recovered uneventfully, with no complications reported during a 6-month follow-up.</div></div><div><h3>Discussion</h3><div>This case highlights the diagnostic challenges in differentiating choledochal cysts from hydatid cysts, particularly in endemic regions. The use of MRCP was pivotal in achieving an accurate diagnosis and guiding definitive management. Early surgical intervention minimized the risks of complications and malignancy.</div></div><div><h3>Conclusion</h3><div>Type IV-A choledochal cysts can present atypically, mimicking hydatid cysts. Advanced imaging, especially MRCP, is critical for accurate diagnosis and management.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110898"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eiad Khouri, Jafar Hamdy, Mohammad Alsheekh Kadour
{"title":"Surgical management of the second cavernous lymphangioma in the tongue globally: A case report","authors":"Eiad Khouri, Jafar Hamdy, Mohammad Alsheekh Kadour","doi":"10.1016/j.ijscr.2025.110863","DOIUrl":"10.1016/j.ijscr.2025.110863","url":null,"abstract":"<div><h3>Introduction and importance</h3><div>Oral Lymphangioma is a rare benign tumor that arises from the lymphatic vessels in oral cavity. It is a development defect in the lymphatic system, which is less common than other types of vascular anomalies, and the incidence in the general population is very low, especially in the oral cavity. It typically presents as soft, painless swelling, often found on the tongue, lips or floor or the mouth. The lesions can vary in size and may have a translucent appearance, sometimes resembling a cyst.</div></div><div><h3>Case presentation</h3><div>A 13-year-old male complaint of congenital diffuse, painless swelling of the lateral side of the tongue. The swelling was soft and compressible and involved half of the tongue. Incisional biopsy from the lesion can confirm the diagnosis by showing dilated lymphatic vessels histologically.</div></div><div><h3>Clinical discussion</h3><div>Oral lymphangioma is a rare tumor found in the oral cavity, occurring at various sites but most commonly on the tongue. This often leads to macroglossia, presenting as a compressible, painless swelling that typically necessitates surgical excision when it causes functional issues.</div></div><div><h3>Conclusion</h3><div>Oral lymphangioma generally has a good prognosis, especially when treated appropriately. However, they can recur if not completely excised.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110863"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed A. Almass , Mariyah E. Alzayer , Hussam J. Alsafwani , Alaa A. Salim , Mohammed Al Duhileb
{"title":"Carcinoma in a male accessory breast; Case report with literature review","authors":"Ahmed A. Almass , Mariyah E. Alzayer , Hussam J. Alsafwani , Alaa A. Salim , Mohammed Al Duhileb","doi":"10.1016/j.ijscr.2025.110949","DOIUrl":"10.1016/j.ijscr.2025.110949","url":null,"abstract":"<div><h3>Introduction and importance</h3><div>Accessory breast is a rare condition where regression of the mammary ridge fails. This ectopic breast can function as the same pectoral breast and respond to hormonal effects. Furthermore, in rare cases, it can develop into malignancy. A malignant accessory breast is very rare, especially in male patients. Although it had first been reported in a male in 1957, there were only a few reported cases following that with no sufficient epidemiological data.</div></div><div><h3>Case presentation</h3><div>A 60-year-old male with right axilla swelling is thought to be a benign lesion for excision. However, histopathology study of the specimen showed malignant cells, and a diagnosis of metastasis has been made and referred to our hospital. We did a full staging workup and eventually diagnosed him with primary accessory breast carcinoma, cT1N0M0.</div></div><div><h3>Clinical discussion</h3><div>Diagnosis of male accessory breast cancer is challenging. Patients usually present with painless swelling. As it is very rare, the possibility of metastasis needs to be ruled out before the diagnosis is made. No current diagnostic and treatment guidelines for accessory breast cancer, and in current practice physicians follow the guidelines of regular breast cancer. Another difficulty with this disease is the estimation of its prognosis.</div></div><div><h3>Conclusion</h3><div>Although accessory breast cancer is rare, it can be seen even in males. In patients with a lesion alongside the milk line, accessory breast cancer should be on the differentials list. Further studies regarding epidemiology, diagnostics, treatment plan, and prognosis of the disease need to be carried out.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110949"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgios I. Karaolanis , Corinne Geppert , Konstantinos Kotopoulos , Drosos Kotelis , Vladimir Makaloski
{"title":"Custom-made fenestrated Anaconda™ leg extension internal iliac artery aneurysm: A case report","authors":"Georgios I. Karaolanis , Corinne Geppert , Konstantinos Kotopoulos , Drosos Kotelis , Vladimir Makaloski","doi":"10.1016/j.ijscr.2024.110790","DOIUrl":"10.1016/j.ijscr.2024.110790","url":null,"abstract":"<div><h3>Introduction and importance</h3><div>Internal iliac artery aneurysms repair represents a life-threatening condition due to their anatomical position and the risk of rupture. Iliac branch devices are strongly recommended for anatomically suitable patients, but limited alternatives exist when their use is unsuitable. The use of custom-made fenestrated endografts is well documented in other aortic territories, however, their application for the treatment of internal iliac artery aneurysm remains limited.</div></div><div><h3>Case presentation</h3><div>In this innovative technique case report, we demonstrate the use of a custom-made fenestrated Anaconda™ leg extension for treating an internal iliac artery aneurysm. In the present report, we describe this technique in a patient unfit for open repair and no suitable for iliac branch device (IBD) treatment.</div></div><div><h3>Clinical discussion</h3><div>Iliac branch devices have been designed for the treatment of iliac artery aneurysms and are associated with high technical success rates and low patient morbidity. However, their use is unsuitable for certain anatomies, and alternative therapeutic options are sparsely reported in the literature. Custom-made devices represent a feasible treatment option for aortic aneurysm repair, but despite their success in other settings, their role in treating internal iliac artery aneurysms remains poorly defined.</div></div><div><h3>Conclusion</h3><div>Custom made iliac fenestrated devices may be a valuable treatment option for patients not eligible for IBD devices.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110790"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142956918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of nasopharyngeal stenosis post-tonsillectomy using the Madame Butterfly technique: A case report with novel approach.","authors":"Amir Soltaniesmaeili, Fateme Farhadipour, Shayan Yousufzai, Hossein Hosseini, Saeed Farjam, Alireza Yousefi","doi":"10.1016/j.ijscr.2025.110935","DOIUrl":"10.1016/j.ijscr.2025.110935","url":null,"abstract":"<p><strong>Background: </strong>Nasopharyngeal stenosis (NPS) is an uncommon but significant complication that arise following tonsillectomy in adults, leading to manifestations including obstructive sleep apnea and dysphagia. This condition is often rare, underscoring the need for awareness and effective management strategies.</p><p><strong>Case presentation: </strong>We present a case involving a 48-year-old female who developed nasopharyngeal stenosis (NPS) 15 months after undergoing a tonsillectomy. Her medical history was unremarkable, with no identifiable predisposing factors. She experienced respiratory distress, snoring, and dysphagia due to significant nasopharyngeal obstruction caused by fibrotic adhesions. The Madame Butterfly flap technique was employed, facilitating effective reconstruction while minimizing complications typically associated with skin grafts.</p><p><strong>Discussion: </strong>The existing literature on NPS in adults is limited, particularly regarding standardized management protocols. Current treatment modalities exhibit considerable variability; however, few have undergone rigorous investigation within adult populations. The Madame Butterfly technique is particularly noteworthy for its ability to achieve both functional and aesthetic repair without the drawbacks associated with traditional grafting methods. This case underscores the necessity for comparative studies involving larger sample sizes to determine optimal management strategies for NPS.</p><p><strong>Conclusion: </strong>This case exemplifies the successful implementation of the Madame Butterfly technique in managing NPS following tonsillectomy, with no recurrence observed during a six-month follow-up period. Given the rarity of NPS and the lack of established protocols, there is an urgent need for updated postoperative guidelines to mitigate this complication. Future research should prioritize the development of standardized management approaches to improve surgical outcomes for patients affected by NPS.</p>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110935"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case report: Vulvar metastasis after lung metastasis in cervical squamous cell carcinoma, a case report and literature review.","authors":"Ze-Lan Liao, Ka-Na Wang, Jia-Wen Zhang","doi":"10.1016/j.ijscr.2025.110816","DOIUrl":"10.1016/j.ijscr.2025.110816","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Cervical cancer is highly correlated with high-risk human papillomavirus (HPV) infection, accounting for approximately 70 % of cases. However, false-negative HPV test results can occur, complicating early detection.</p><p><strong>Case presentation: </strong>We introduce a rare case of cervical cancer with lung metastasis followed by vulvar metastasis. Notably, the HPV test was negative at diagnosis but became positive upon detection of vulvar metastasis.</p><p><strong>Clinical discussion: </strong>We discuss the pathways of vulvar metastasis in cervical cancer and potential causes of false-negative HPV tests. A search for cases of vulvar metastasis of cervical cancer in Medline and Embase between 2004 and 2024 was performed and a literature review was conducted.</p><p><strong>Conclusion: </strong>The occurrence of vulvar metastasis indicates the terminal manifestation of the tumor and the survival period is short. Active radiotherapy, chemotherapy, immunotherapy and other multiple treatments may increase the overall survival time of patients.</p>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110816"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Palliative management of malignant duodenocolic fistula: Case report on endoscopic duodenal stent placement and its clinical implications.","authors":"Guro Bjørnå, Mai-Britt Worm Ørntoft, Claudia Jaensch","doi":"10.1016/j.ijscr.2025.110918","DOIUrl":"10.1016/j.ijscr.2025.110918","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Malignant duodenocolic fistulas are a rare but serious complication of advanced colorectal cancer. With the growing elderly population and increasing incidence of advanced colorectal cancer, there is a pressing need to explore palliative alternatives to complete resection, especially when a patient's overall health precludes extensive surgery.</p><p><strong>Case presentation: </strong>This case report presents a palliative approach involving luminal stent placement via gastroscopy in a patient with non-resectable, locally invasive colorectal cancer, resulting in a malignant duodenocolic fistula.</p><p><strong>Clinical discussion: </strong>We discuss different palliative treatment strategies against malignant duodenocolic fistulas, including endoscopic luminal stent placement and specific technical aspects of this procedure, highlighting factors that may contribute to a successful clinical outcome.</p><p><strong>Conclusion: </strong>Endoscopic stent placement can represent a minimally invasive palliative strategy to provide symptom relief in a patient with advanced colorectal cancer. Treatment strategy should be considered on a individual basis and in close consultation with the patient.</p>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110918"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Sabah, Alexis Marouk, Louis Vallois, Chérif Akladios
{"title":"Case report of an omental metastasis of melanoma in a patient with abdominal pain.","authors":"Jonathan Sabah, Alexis Marouk, Louis Vallois, Chérif Akladios","doi":"10.1016/j.ijscr.2025.110988","DOIUrl":"10.1016/j.ijscr.2025.110988","url":null,"abstract":"<p><strong>Introduction: </strong>Choroidal melanoma primarily metastasizes to the liver, but rare sites like the omentum can also be affected, making this case educational due to its uncommon presentation. The decision to pursue surgical treatment for metastatic melanoma remains controversial.</p><p><strong>Case presentation: </strong>A woman in her 60s, with a history of a stable choroidal nevus, experienced rapid lesion growth, leading to enucleation and radiotherapy. Two years later, she developed severe epigastric pain. Imaging revealed peritoneal nodules, and histopathology confirmed metastatic choroidal melanoma. Molecular analysis identified a GNAQ G48L mutation.</p><p><strong>Discussion: </strong>Omental metastasis in choroidal melanoma is rare, and while surgery is uncommon for metastatic melanoma, it was performed to alleviate symptoms and improve functionality. Following omentectomy and immunotherapy, her condition remained stable for two years.</p><p><strong>Conclusion: </strong>This case emphasizes the importance of recognizing atypical metastatic sites in melanoma. Surgical intervention, though rare, can be beneficial for symptom relief in selected cases, improving outcomes when combined with targeted treatments.</p>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110988"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Doxycycline sclerotherapy as a primary treatment of head and neck giant cystic hygroma: A case report study.","authors":"Waddah Al-Saadie","doi":"10.1016/j.ijscr.2025.110945","DOIUrl":"10.1016/j.ijscr.2025.110945","url":null,"abstract":"<p><strong>Introduction: </strong>Cystic hygroma is a benign lymphatic malformation, developing around 6th gestational week. The big challenge is in the way they are managed due to their extension within the vital elements. Treatment options include watchful waiting, surgery, sclerotherapy and combination between them in some cases.</p><p><strong>Case presentation: </strong>We present a rare case of giant cystic hygroma of a 11-month-old male was referred to the Department of Otolaryngology for an asymptomatic, aesthetically unappealing swelling in the neck since 9 months. A well-defined large cystic mass measures about (4 × 7 × 9 cm) was seen in the CT scan, originating at the left lateral neck. It extends from the left submandibular space inferiorly posterior to the sternocleidomastoid muscle, and retrosternally to the aortic arch level. From the Posterior aspect, the mass reaches the prevertebral space. No lymph adenopathy was noted. No bony erosions. Findings are suggestive of Cystic Higroma (CH).The primary treatment was sclerotherapy using doxycycline for one time. The procedure was performed at an operating theatre under general anesthesia because injection of the sclerosant factor is painful. The child was monitored for 3 months after the procedure (with an interval of one month between each observation). There was a noticeable improvement after 4 weeks and the complete resolution of the cystic hygroma was observed 12 weeks after the initial procedure. During the monitoring period of 6 months, the lesion did not show any recurrence.</p><p><strong>Clinical discussion: </strong>In this case of giant Cystic Higroma (CH) significantly decreased after using of Doxycycline sclerotherapy for one time only without the need to repeat the procedure more than once. So clinicians should be aware of this good treatment of (CH) because it offers minimal patient trauma and excellent outcomes.</p><p><strong>Conclusion: </strong>Through the good results we have reached from this case, we encourage its application extensively in the future to more cases due to their safety and quick results.</p>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110945"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meimei Gao, Gang Chen, Juanqin Niu, Yonghua Huang, Wei Xue
{"title":"A case report of gallstone ileus caused by biliary-intestinal fistula: Multidetector computed tomography features analysis.","authors":"Meimei Gao, Gang Chen, Juanqin Niu, Yonghua Huang, Wei Xue","doi":"10.1016/j.ijscr.2025.110993","DOIUrl":"10.1016/j.ijscr.2025.110993","url":null,"abstract":"<p><strong>Introduction and significance: </strong>Gallstone ileus is a mechanical intestinal obstruction caused by gallstones or stones from the common bile duct entering the intestinal canal through a biliary-intestinal fistula and becoming impacted. Multidetector computed tomography (MDCT) scanning is the most important auxiliary diagnostic method for this disease.</p><p><strong>Case presentation: </strong>We report a rare case of gallstone ileus involving an elderly female patient and analyze the characteristics of the MDCT images: atrophic cholecystitis, gallstones, the formation of a local duodenal-gallbladder fistula, pneumatosis in the intrahepatic bile ducts of the left lobe of the liver and some extrahepatic bile ducts, intestinal mechanical obstruction, and the presence of an ectopic stone. A partial small bowel resection was performed and the stone was removed.</p><p><strong>Clinical discussion: </strong>Gallstone ileus is a rare disease that often occurs in elderly women. It has no specific clinical symptoms and is prone to delayed diagnosis and treatment. MDCT scanning is the most sensitive and accurate diagnostic method for gallstone ileus, once the disease is clearly diagnosed, surgical treatment is recommended as soon as possible.</p><p><strong>Conclusion: </strong>The aim of this study is to elevate the understanding and treatment of gallstone ileus.</p>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110993"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}