International Journal of Surgery Case Reports最新文献

{"title":"Commentary on \"Rare case of postpartum septic arthritis of the shoulder caused by multi-drug resistant Kingella kingae: A case report\".","authors":"Mohammadreza Sabouri, Vahideh Poyesh, Saeed Shojaei","doi":"10.1016/j.ijscr.2025.110994","DOIUrl":"10.1016/j.ijscr.2025.110994","url":null,"abstract":"","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110994"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double trouble: A case report of concurrent superior mesenteric artery syndrome and nutcracker syndrome in a previously healthy young adult.","authors":"Melika Boroomand-Saboor, Hamid Moradi","doi":"10.1016/j.ijscr.2025.110968","DOIUrl":"10.1016/j.ijscr.2025.110968","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Superior Mesenteric Artery (SMA) syndrome and Nutcracker Syndrome are rare vascular compression disorders that can lead to significant gastrointestinal and renal complications. SMA syndrome occurs when the duodenum is compressed between the aorta and the SMA, resulting in symptoms such as nausea, vomiting, and abdominal pain. Nutcracker Syndrome, on the other hand, involves the compression of the left renal vein, leading to renal venous hypertension and associated symptoms. The simultaneous occurrence of these two conditions is exceedingly rare and poses diagnostic and therapeutic challenges.</p><p><strong>Case presentation: </strong>This case report describes a 36-year-old male who presented with a four-week history of postprandial abdominal pain, nausea, vomiting, and significant weight loss. Imaging studies, including CT angiography, revealed duodenal compression by the SMA, consistent with SMA syndrome, as well as compression of the left renal vein, indicative of Nutcracker Syndrome.</p><p><strong>Clinical discussion: </strong>The coexistence of SMA syndrome and Nutcracker Syndrome raises intriguing questions about their underlying mechanisms. Anatomical variations in vascular structures may predispose individuals to both conditions. Treatment typically involves nutritional support and, in severe cases, surgical intervention. This case highlights the importance of a multidisciplinary approach to diagnosis and management.</p><p><strong>Conclusion: </strong>This report underscores the need for a thorough evaluation in patients presenting with symptoms of vascular compression. Early diagnosis and a collaborative treatment approach can lead to favorable outcomes.</p>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110968"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of advanced gallbladder adenocarcinoma: A case report and review of treatment strategies.","authors":"Collins Saa Bowah, Charles John Nhungo, Jabu A Mavundla, Ally H Mwanga, Charles A Mkony, Cameron E Gaskill","doi":"10.1016/j.ijscr.2025.110965","DOIUrl":"10.1016/j.ijscr.2025.110965","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Gallbladder cancer (GBC) is a rare but aggressive malignancy, accounting for most biliary tract cancers. It typically presents at an advanced stage, leading to a poor prognosis, with a mean survival of six months and a five-year survival rate of 17.6 %. Early detection is critical due to its insidious onset and rapid progression.</p><p><strong>Case presentation: </strong>We report a case of a 46-year-old African male who presented with a two-week history of colicky abdominal pain. Diagnostic imaging revealed a gallbladder mass, and the patient underwent surgical resection followed by adjuvant therapy. Postoperative recovery was initially satisfactory; however, 18 months later, the patient developed peritoneal carcinomatosis and succumbed to the disease.</p><p><strong>Clinical discussion: </strong>This case highlights the challenges of managing GBC in resource-limited settings, where late-stage presentation is common. Early surgical intervention remains the mainstay of potentially curative treatment. Adjuvant therapies may improve outcomes but are often less effective in advanced disease stages.</p><p><strong>Conclusion: </strong>Early detection and surgical management are pivotal for improving survival outcomes in gallbladder cancer. This case emphasizes the need for heightened clinical awareness and improved diagnostic capabilities in resource-constrained environments.</p>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110965"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 25-year neglected giant anterior urethral stone associated with urethral diverticulum and urethrocutaneous fistula: A case report.","authors":"Arief Fadli Putra, Ronald Sugianto, M Zhafirrahman, Muhamad, Pande Made Wisnu Tirtayasa","doi":"10.1016/j.ijscr.2025.110972","DOIUrl":"10.1016/j.ijscr.2025.110972","url":null,"abstract":"<p><strong>Introduction: </strong>Urethral stone (US) is an uncommon disease that may be associated with other conditions. It's interesting if the patient neglected his disease after decades. This case report discusses the giant anterior urethral stone, as well as the neglect in the peripheral area.</p><p><strong>Presentation of case: </strong>A 43-year-old man was referred to our hospital with a complaint of scrotal pain 4 days ago. He also complained about weak urine stream, a big-palpable mass, and a small opening in the scrotum that had appeared for many years. There was a history of recurrent urinary pain and purulent urine. Physical examination confirmed a solid-palpable and rounded mass with a meatus in the scrotum. Computed tomography (CT) revealed a giant stone. We performed an open surgery and extracted a 6.8 × 4.5 × 3 cm stone from the bulbous urethra and continued to urethral diverticulectomy.</p><p><strong>Discussion: </strong>Neglected US could lead to serious complications if left untreated. This may be caused by lack of knowledge, low socioeconomic status, and negative stigma of urological diseases. Our case became complicated as the patient never came to seek medical help. Geographical and cultural limitations may also contribute to that situation. The current case was found to be more challenging due to limited resources and referral rejection. Finally, this case proved that open surgery can successfully treat the giant US and enhance the quality of life.</p><p><strong>Conclusion: </strong>Immediate access to health care services in limited resource settings, is essential for early interventions of US in preventing further complications.</p>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"110972"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in diagnosis and management of xanthogranulomatous salpingo-oophoritis: A rare case","authors":"Mahalakshmi Gaddi ,&nbsp;Sahana Surpur ,&nbsp;Vidya Kamat ,&nbsp;Zoha Khan ,&nbsp;Mayur Wanjari ,&nbsp;Gaurav Mittal","doi":"10.1016/j.ijscr.2024.110778","DOIUrl":"10.1016/j.ijscr.2024.110778","url":null,"abstract":"<div><h3>Introduction and importance</h3><div>Xanthogranulomatous inflammation of the female genital tract is a rare condition involving ovarian tubes characterized by chronic inflammation and destruction of pelvic organs, often mimicking pelvic malignancy.</div></div><div><h3>Case presentation</h3><div>A 37-year-old female with a history of chronic kidney disease, hypertension, and treated pulmonary tuberculosis, presented with lower abdominal fullness, pain, and irregular menstrual cycles.</div></div><div><h3>Clinical discussion</h3><div>Radiological investigations revealed a significant left adnexal mass, suggesting a tubo-ovarian abscess or neoplastic lesion. Staging laparotomy was performed, and intraoperatively, the mass was found adherent to surrounding organs. A frozen section analysis indicated a benign lesion and a hysterectomy was deferred. Histopathological evaluation confirmed the diagnosis of xanthogranulomatosis salpingo-oophoritis.</div></div><div><h3>Conclusion</h3><div>This case underscores the importance of considering rare inflammatory conditions in the differential diagnosis of pelvic masses. It highlights the challenges in management, including the risk of extensive surgeries leading to infertility. Thorough investigation and accurate diagnosis are crucial for appropriate management and to minimize unnecessary interventions.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110778"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142956914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clear cell hidradenoma of the male breast: A case report and literature review","authors":"Guihua Wang ,&nbsp;Xinyi Ma ,&nbsp;Wenbing Wei ,&nbsp;Wanqi Yao ,&nbsp;Fei Cheng","doi":"10.1016/j.ijscr.2025.110887","DOIUrl":"10.1016/j.ijscr.2025.110887","url":null,"abstract":"<div><h3>Introduction</h3><div>Clear cell hidradenoma (CCH) is a rare type of benign breast tumor that may undergo malignant transformation in a few cases. It clinically manifests as a painless breast mass, and may include nipple discharge. Complete surgical excision with adequate safety margins is the primary treatment.</div></div><div><h3>Presentation of case</h3><div>A 34-year-old man developed a mass beneath the left nipple over 2 years. Although the mass was painless, it gradually enlarged over time and was accompanied by nipple discharge. Complete excision of the mass revealed that the tumor cells were arranged in solid nodule-like structures composed of clear cells and few cells with eosinophilic cytoplasm. Based on the results of immunohistochemical staining and <em>MAML2</em> rearrangement analysis, a pathological diagnosis of breast CCH was made. The patient was followed up postoperatively for six months, during which there was no recurrence.</div></div><div><h3>Discussion</h3><div>Breast CCH differentiates from low-grade mucoepidermoid, glycogen-rich, and lipid-rich breast carcinomas. A more comprehensive understanding of breast CCH can aid pathologists in avoiding misdiagnoses during fine-needle aspiration biopsy and intraoperative frozen section diagnosis. Diagnostic clues for CCH include: (1) the presence of two types of cell morphology in the tumor, (2) immunohistochemical staining indicating p63 positivity, (3) negativity for myoepithelial markers, and (4) <em>MAML2</em> gene rearrangement in certain cases.</div></div><div><h3>Conclusion</h3><div>The case we reported occurred in a male patient with MAML2 gene rearrangement, which is extremely rare. Complete surgical excision with adequate safety margins is the primary treatment method for breast CCH, and close postoperative follow-up should be conducted to monitor disease recurrence.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110887"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11783126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous true brachial artery aneurysm: A case report from Somalia","authors":"Abdijalil Abdullahi Ali ,&nbsp;Abdinafic Mohamud Hussein ,&nbsp;Hassan Kalif Abdi ,&nbsp;Ali Abdulkadir Ali Siyad ,&nbsp;Ali Mohamed Warsame Keilie ,&nbsp;Fatima Mohamud Ahmed","doi":"10.1016/j.ijscr.2025.110866","DOIUrl":"10.1016/j.ijscr.2025.110866","url":null,"abstract":"<div><h3>Introduction and importance</h3><div>True brachial artery aneurysms are rather uncommon, due to their number of etiological factors. Besides inducing symptoms such as hand or digit ischemia, they may present as pulsative tumefactions and cause pain or paresthesias through nerve impingement. The diagnosis is based on duplex ultrasonography, CTA in the operational planning phase, and a physical examination.</div></div><div><h3>Case presentation</h3><div>A 28 year old female patient was attending our center with pain and swelling of the left arm because of a brachial artery aneurysm. The patient underwent successful excision of the aneurysmal sac followed by brachial artery reconstruction with a prosthetic graft.</div></div><div><h3>Clinical discussion</h3><div>Brachial artery aneurysms are defined as dilation greater than 50 % of the normal diameter. The pathophysiologic mechanism of brachial artery aneurysms involves local hemodynamic factors such as increased flow that lead to endothelial production of nitric oxide and reactive oxygen species, resulting in upregulation of matrix metalloproteinase production and damage to the arterial wall.</div></div><div><h3>Conclusion</h3><div>There is some evidence linking the creation of an AVF with the occurrence of BAA. Immunosuppression might also add to the charter of risk factors leading to aneurysmal events. Surgical repair is generally the method of choice although in selected cases, the endovascular approach may be employed. When an autologous vein is not available, the use of a synthetic graft may be a reasonable option when performing artery reconstruction.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110866"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastric outlet obstruction in an 11-year-old girl due to a pyloric diaphragm – A case report and a systematic literature review","authors":"Omran Janoud,&nbsp;Talal Abou Moughdib,&nbsp;Majd Hamed Nasser,&nbsp;Obaida Abo Fakher,&nbsp;Rani Saab,&nbsp;Houssain AL-Halabi","doi":"10.1016/j.ijscr.2025.110882","DOIUrl":"10.1016/j.ijscr.2025.110882","url":null,"abstract":"<div><h3>Introduction</h3><div>Congenital pyloric web or diaphragm are rare causes of Gastric Outlet Obstruction (GOO) after infancy, representing approximately 1 % of gastrointestinal obstructions. While it typically presents in the neonatal period with nonbilious vomiting, delayed diagnosis beyond infancy is exceptionally rare.</div></div><div><h3>Presentation of the case</h3><div>An 11-year-old girl with presented with one-month history of postprandial vomiting. Her medical history was unremarkable and clinical examination and laboratory investigations were normal. A barium meal X-ray revealed narrowing at the gastric outlet. Endoscopy showed severe pyloric narrowing with undigested food in the stomach. Due to the severity of the stenosis, the endoscope could not traverse and surgical intervention was required.</div></div><div><h3>Discussion</h3><div>Pyloric webs and diaphragms are considered rare causes of congenital GOO. Confirmation of the diagnosis requires an upper contrast study or endoscopy. Gastric outlet obstruction can manifest with various symptoms. The clinical onset varies depending on the underlying cause. We conducted a systematic literature review of all case reports and series focused on GOO patients over 10 years old due to webs or diaphragms. The review reveals that symptoms are varied and may persist for years before diagnosis due to the rarity of these anomalies and their nonspecific presentations. This review highlights the importance of follow-up period after treatment due to the risk of recurrence.</div></div><div><h3>Conclusion</h3><div>This case emphasizes the importance of conducting endoscopy or abdominal X-rays with barium meals in evaluating persistent gastrointestinal symptoms, particularly in female patients.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110882"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare massive thoracic metastasis of endometrial cancer: Chest wall demolition and reconstruction. A case report","authors":"Antonio Burlone,&nbsp;Simone Tombelli,&nbsp;Domenico Viggiano,&nbsp;Sara Borgianni,&nbsp;Alessandro Gonfiotti","doi":"10.1016/j.ijscr.2025.110825","DOIUrl":"10.1016/j.ijscr.2025.110825","url":null,"abstract":"<div><h3>Introduction</h3><div>Distant recurrences are a major problem after surgical treatment for endometrial carcinoma; metastases to the bone are usually restricted to the axial skeleton, cases of costal localization are few. We present a case of a massive costal metastases successfully treated in our department.</div></div><div><h3>Case presentation</h3><div>A 60-year-old woman underwent bilateral hysteroannessectomy followed by adjuvant radiotherapy for endometrial adenocarcinoma pT3a FIGO IIIA. Follow-up was uneventful until an occasional chest x-ray was made: a lesion of 7,5 × 5,4 × 5,6 cm in dimension was found at the left sixth rib, compatible with endometrial origin after biopsy. Despite chemo and radiotherapy the lesion incremented in size showing no response to treatment: 20 × 22 × 22 cm. Once she came to our attention, surgical treatment was planned after multidisciplinary discussion: we performed a left ribs V-IX en-block resection with the mass. We restored the chest wall using a biological prothesis in association with 3 titanium rib bars. The chest wall defect was covered with a myocutaneous flap (latissimus dorsi, serratus anterior, pectoralis major and obliquus externus).</div></div><div><h3>Clinical discussion</h3><div>bone metastases from endometrial carcinoma are reported with a mean diameter of 5 cm; in our report the huge lesion represents a high-risk scenario for post-operative complications. In this setting surgical resection with complex multimodality reconstruction is needed.</div></div><div><h3>Conclusions</h3><div>This case is characterised by the rare localization and giant dimension of an endometrial metastasis. This report aims to describe the decision-making process, the successful demolition and reconstruction of the chest wall.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110825"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic appendectomy secondary to afebrile acute perforated appendicitis mimicking threatened abortion in first trimester pregnancy in Tanzania: A case report","authors":"Harold L. Mashauri ,&nbsp;Kasimu B. Ndyamukama ,&nbsp;Alfred G. Nyamwihula ,&nbsp;Anthony M. Mapande","doi":"10.1016/j.ijscr.2025.110879","DOIUrl":"10.1016/j.ijscr.2025.110879","url":null,"abstract":"<div><h3>Introduction</h3><div>Appendicitis in pregnancy is the most common non-obstetric surgical condition which requires urgent evaluation and immediate intervention in a multidisciplinary approach. Pregnancy anatomical and physiological changes can mask the presentation of appendicitis and poses both diagnostic and management challenges.</div></div><div><h3>Case presentation</h3><div>A 32 year old female, G3P2L2 at gestation age of 11 weeks by USS, presented with recurrent episodes of acute abdominal pain for one day, afebrile but accompanied with poor appetite, nausea and vomiting along episodes of per vaginal spotting which started three days prior. She was initially diagnosed and treated as a threatened abortion case with no improvement of symptoms. Abdominal pain was refractory to analgesics. Abdominal pelvic USS was done twice and revealed no features of appendicitis while obstetric USS was unremarkable. Clinical examination revealed an Alvarado score of 7. A diagnostic laparoscopy confirmed acute perforated appendicitis and she underwent laparoscopic appendectomy with uneventful post-operative recovery.</div></div><div><h3>Discussion</h3><div>Acute appendicitis is challenging to diagnose and manage during pregnancy due to symptoms overlapping with maternal physiological and anatomical changes along with obstetric presentations like threatened abortion. Appendicitis scoring systems like the Alvarado score are still reliable diagnostic tools even during pregnancy while the use of preferred imaging like USS is more limited secondary to gravid uterus.</div></div><div><h3>Conclusion</h3><div>All pregnant women with acute abdomen pain and suspecting features of acute appendicitis should be screened thoroughly for the condition. Diagnostic laparoscopy is useful and friendly in diagnosis and management in pregnancy. Multidisciplinary approach in evaluating and managing such cases in pregnancy is of high clinical benefits for maternal-fetal outcomes.</div></div>","PeriodicalId":48113,"journal":{"name":"International Journal of Surgery Case Reports","volume":"127 ","pages":"Article 110879"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}