Bangladesh Journal of Endocrinology and Metabolism最新文献

{"title":"Unilateral Hypoplastic Ovary with Ipsilateral Partial Hypoplastic Fallopian Tube on Laparoscopy – An Incidental Finding in a Parous Woman","authors":"Olivia Marie Jacob, Vijayan Sharmila, K. Garikapati","doi":"10.4103/bjem.bjem_15_24","DOIUrl":"https://doi.org/10.4103/bjem.bjem_15_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 Asymptomatic unilateral hypoplastic ovary in a parous fertile woman is rare. Hypoplastic or streak ovaries are usually associated with subfertility or premature menopause. We report a rare case of a fertile parous woman who approached us for sterilization procedure. Her ultrasonogram was found to be normal. During laparoscopy, unilateral ovary and tube were hypoplastic.","PeriodicalId":479958,"journal":{"name":"Bangladesh Journal of Endocrinology and Metabolism","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141801354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Young Male with Delayed Puberty and Poor Social Skills","authors":"Mohammad Moin Shahid","doi":"10.4103/bjem.bjem_10_24","DOIUrl":"https://doi.org/10.4103/bjem.bjem_10_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 Klinefelter syndrome (KS) is a chromosomal disorder characterized by the presence of one or more extra X chromosomes in males, affecting physical, cognitive, and social development. This case report describes a rare mosaic variety of KS with a karyotype of 48, XXXY. We present the clinical features, diagnostic process, and management of a patient with this unique mosaic chromosomal pattern. The case highlights the importance of recognizing atypical presentations of KS and the challenges associated with the diagnosis and treatment of rare mosaic varieties.","PeriodicalId":479958,"journal":{"name":"Bangladesh Journal of Endocrinology and Metabolism","volume":" 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141371527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Gestational Diabetes Mellitus be Prevented?","authors":"Tanjina Hossain","doi":"10.4103/bjem.bjem_13_24","DOIUrl":"https://doi.org/10.4103/bjem.bjem_13_24","url":null,"abstract":"","PeriodicalId":479958,"journal":{"name":"Bangladesh Journal of Endocrinology and Metabolism","volume":" 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141373991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Efficacy of Semaglutide Use in Diabetes during Ramadan Fasting: A Real-world Experience from Bangladesh","authors":"M. Pathan, Nazma Akter, S. Selim, Md Feroz Amin, F. Afsana, M. Saifuddin, A. Kamrul-Hasan, M. Mustari, Ashish Kumar Chakraborty, Riad M. M. Hossain","doi":"10.4103/bjem.bjem_29_23","DOIUrl":"https://doi.org/10.4103/bjem.bjem_29_23","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 The study has been conducted to observe the efficacy and safety of once-weekly subcutaneous semaglutide during Ramadan fasting among patients with type 2 diabetes mellitus (T2DM) from Bangladesh who intended to fast during Ramadan 2022.\u0000 \u0000 \u0000 \u0000 This was an open-label, single-center, two-arm parallel-group study. In this prospective observational study, patients were enrolled in two groups depending on treated with or without semaglutide for at least 3 months prior Ramadan. Initially, total 200 patients were enrolled at the first visit (4 weeks before Ramadan); among them, 58 subjects were in the semaglutide group (Group A) and 142 in other than the semaglutide group (Group B). At the end of the second visit (within 4 weeks after Ramadan) after data editing and cleaning, a total of 130 patients (55 subjects in Group A and 75 subjects in Group B) were included in the final statistical analysis. All of them were followed up for a total of 24 weeks including 12 weeks of screening period. The primary objectives were to assess the efficacy and safety of semaglutide in terms of glycosylated hemoglobin (HbA1c) (%), weight loss (kg), hypoglycemia (number of events), and episodes of gastrointestinal (GI) upset (number of events) during Ramadan fasting.\u0000 \u0000 \u0000 \u0000 Patients in the semaglutide group had better glycemic control after fasting of Ramadan compared to the control group (mean decrease in HbA1c level: 0.61% vs. 0.19%; P < 0.001). In addition, more than 18% of the patients in the semaglutide group achieved good glycemic control (HbA1c <7%), while the rate was 13.3% in the control group. Patients treated with semaglutide achieved a better weight loss than the nonsemaglutide group (2.97 vs. 1.38 kg; P < 0.001). Although there was no significant difference in terms of hypoglycemic events in both the groups (P = 0.13), but the GI symptoms were more common in the semaglutide group than the control group (P < 0.05). Among other secondary endpoints, the serum levels of total cholesterol, low-density lipoprotein, and triglyceride were significantly decreased in the semaglutide group compared to the control group (P < 0.05).\u0000 \u0000 \u0000 \u0000 Semaglutide showed better efficacy in glycemic control, weight loss, and dyslipidemia compared to other hypoglycemic drugs in patients with T2DM during Ramadan. Although patients receiving semaglutide reported fewer hypoglycemic episodes and GI upset events, they might be subjected to other medications or prolonged fasting. Semaglutide might be considered a suitable therapy during Ramadan fasting based on judicial judgment.\u0000","PeriodicalId":479958,"journal":{"name":"Bangladesh Journal of Endocrinology and Metabolism","volume":"38 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139957419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}