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Refined use of the eye-mind hypothesis for scientific argumentation using multiple representations 在使用多重表征的科学论证中精细地使用眼-心假设
IF 2.5 3区 教育学
Instructional Science Pub Date : 2022-03-24 DOI: 10.1007/s11251-022-09581-w
Chao-Jung Wu, Chia-Yu Liu
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引用次数: 5
Outside the standard test: The development of a model-based assessment and corresponding rubric 标准测试之外:开发基于模型的评估和相应的标题
IF 2.5 3区 教育学
Instructional Science Pub Date : 2022-03-23 DOI: 10.1007/s11251-022-09582-9
L. Minshew, Janice L. Anderson, Kerry A. Bartlett
{"title":"Outside the standard test: The development of a model-based assessment and corresponding rubric","authors":"L. Minshew, Janice L. Anderson, Kerry A. Bartlett","doi":"10.1007/s11251-022-09582-9","DOIUrl":"https://doi.org/10.1007/s11251-022-09582-9","url":null,"abstract":"","PeriodicalId":47990,"journal":{"name":"Instructional Science","volume":"50 1","pages":"599 - 624"},"PeriodicalIF":2.5,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44916991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Correction to: Futurising science education: students’ experiences from a course on futures thinking and quantum computing 未来科学教育:学生从未来思维和量子计算课程中获得的经验
IF 2.5 3区 教育学
Instructional Science Pub Date : 2022-03-22 DOI: 10.1007/s11251-022-09588-3
Tapio Rasa, E. Palmgren, Antti Laherto
{"title":"Correction to: Futurising science education: students’ experiences from a course on futures thinking and quantum computing","authors":"Tapio Rasa, E. Palmgren, Antti Laherto","doi":"10.1007/s11251-022-09588-3","DOIUrl":"https://doi.org/10.1007/s11251-022-09588-3","url":null,"abstract":"","PeriodicalId":47990,"journal":{"name":"Instructional Science","volume":"50 1","pages":"449 - 449"},"PeriodicalIF":2.5,"publicationDate":"2022-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45431992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How many words are enough? Investigating the effect of different configurations of a software scaffold for formulating scientific hypotheses in inquiry-oriented contexts 多少字才够?在探究导向的环境中，研究不同配置的软件支架对形成科学假设的影响
IF 2.5 3区 教育学
Instructional Science Pub Date : 2022-03-21 DOI: 10.1007/s11251-022-09580-x
Tasos Hovardas, Z. Zacharia, N. Xenofontos, Ton de Jong
{"title":"How many words are enough? Investigating the effect of different configurations of a software scaffold for formulating scientific hypotheses in inquiry-oriented contexts","authors":"Tasos Hovardas, Z. Zacharia, N. Xenofontos, Ton de Jong","doi":"10.1007/s11251-022-09580-x","DOIUrl":"https://doi.org/10.1007/s11251-022-09580-x","url":null,"abstract":"","PeriodicalId":47990,"journal":{"name":"Instructional Science","volume":"50 1","pages":"361 - 390"},"PeriodicalIF":2.5,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47910298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wild Bitter Melon Extract Abrogates Hypoxia-Induced Cell Death via the Regulation of Ferroptosis, ER Stress, and Apoptosis in Microglial BV2 Cells. 野生苦瓜提取物通过调节小胶质细胞 BV2 细胞的铁氧化、ER 应激和细胞凋亡减轻缺氧诱导的细胞死亡
3区 教育学
Instructional Science Pub Date : 2022-03-16 eCollection Date: 2022-01-01 DOI: 10.1155/2022/1072600
Chih-Hung Lin, Jiunn-Sheng Wu, Po-Chun Hsieh, Valeria Chiu, Chou-Chin Lan, Chan-Yen Kuo
{"title":"Wild Bitter Melon Extract Abrogates Hypoxia-Induced Cell Death via the Regulation of Ferroptosis, ER Stress, and Apoptosis in Microglial BV2 Cells.","authors":"Chih-Hung Lin, Jiunn-Sheng Wu, Po-Chun Hsieh, Valeria Chiu, Chou-Chin Lan, Chan-Yen Kuo","doi":"10.1155/2022/1072600","DOIUrl":"10.1155/2022/1072600","url":null,"abstract":"<p><p>Microglial cells are well-known phagocytic cells that are resistant to the central nervous system (CNS) and play an important role in the maintenance of CNS homeostasis. Activated microglial cells induce neuroinflammation under hypoxia and typically cause neuronal damage in CNS diseases. In this study, we propose that wild bitter melon extract (WBM) has a protective effect on hypoxia-induced cell death via regulation of ferroptosis, ER stress, and apoptosis. The results demonstrated that hypoxia caused microglial BV-2 the accumulation of lipid ROS, ferroptosis, ER stress, and apoptosis. In this study, we investigated the pharmacological effects of WBM on BV-2 cells following hypoxia-induced cell death. The results indicated that WBM reversed hypoxia-downregulated antiferroptotic molecules Gpx4 and SLC7A11, as well as upregulated the ER stress markers CHOP and Bip. Moreover, WBM alleviated hypoxia-induced apoptosis via the regulation of cleaved-caspase 3, Bax, and Bcl-2. Our results suggest that WBM may be a good candidate for preventing CNS disorders in the future.</p>","PeriodicalId":47990,"journal":{"name":"Instructional Science","volume":"34 1","pages":"1072600"},"PeriodicalIF":0.0,"publicationDate":"2022-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74268359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Learning to solve ill-defined statistics problems: does self-explanation quality mediate the worked example effect? 学习解决定义不清的统计问题:自我解释质量是否介导了实例效应?
IF 2.5 3区 教育学
Instructional Science Pub Date : 2022-03-15 DOI: 10.1007/s11251-022-09579-4
S. Bichler, Matthias Stadler, M. Bühner, Samuel Greiff, F. Fischer
{"title":"Learning to solve ill-defined statistics problems: does self-explanation quality mediate the worked example effect?","authors":"S. Bichler, Matthias Stadler, M. Bühner, Samuel Greiff, F. Fischer","doi":"10.1007/s11251-022-09579-4","DOIUrl":"https://doi.org/10.1007/s11251-022-09579-4","url":null,"abstract":"","PeriodicalId":47990,"journal":{"name":"Instructional Science","volume":"50 1","pages":"335 - 359"},"PeriodicalIF":2.5,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48578693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Effects of interactive teacher-generated drawings on students’ understanding of plate tectonics 交互式教师绘图对学生理解板块构造的影响
IF 2.5 3区 教育学
Instructional Science Pub Date : 2022-03-12 DOI: 10.1007/s11251-021-09567-0
Cristiana Lardi, Claudia Leopold
{"title":"Effects of interactive teacher-generated drawings on students’ understanding of plate tectonics","authors":"Cristiana Lardi, Claudia Leopold","doi":"10.1007/s11251-021-09567-0","DOIUrl":"https://doi.org/10.1007/s11251-021-09567-0","url":null,"abstract":"","PeriodicalId":47990,"journal":{"name":"Instructional Science","volume":"50 1","pages":"273 - 302"},"PeriodicalIF":2.5,"publicationDate":"2022-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43586594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Futurising science education: students’ experiences from a course on futures thinking and quantum computing 未来科学教育:学生对未来思维和量子计算课程的体验
IF 2.5 3区 教育学
Instructional Science Pub Date : 2022-02-02 DOI: 10.1007/s11251-021-09572-3
Tapio Rasa, E. Palmgren, Antti Laherto
{"title":"Futurising science education: students’ experiences from a course on futures thinking and quantum computing","authors":"Tapio Rasa, E. Palmgren, Antti Laherto","doi":"10.1007/s11251-021-09572-3","DOIUrl":"https://doi.org/10.1007/s11251-021-09572-3","url":null,"abstract":"","PeriodicalId":47990,"journal":{"name":"Instructional Science","volume":"50 1","pages":"425 - 447"},"PeriodicalIF":2.5,"publicationDate":"2022-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47158370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Figuring out what works: learning and engaging with ideas about evolution within integrated informal learning environments 弄清楚什么是有效的:在整合的非正式学习环境中学习和参与关于进化的想法
IF 2.5 3区 教育学
Instructional Science Pub Date : 2022-01-18 DOI: 10.1007/s11251-021-09576-z
Dina Nesimyan – Agadi, Orit Ben Zvi Assaraf
{"title":"Figuring out what works: learning and engaging with ideas about evolution within integrated informal learning environments","authors":"Dina Nesimyan – Agadi, Orit Ben Zvi Assaraf","doi":"10.1007/s11251-021-09576-z","DOIUrl":"https://doi.org/10.1007/s11251-021-09576-z","url":null,"abstract":"","PeriodicalId":47990,"journal":{"name":"Instructional Science","volume":"50 1","pages":"391 - 424"},"PeriodicalIF":2.5,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42063195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Effects of Group differentiation by students’ learning strategies 群体分化对学生学习策略的影响
IF 2.5 3区 教育学
Instructional Science Pub Date : 2022-01-11 DOI: 10.1007/s11251-021-09575-0
C. Haelermans
{"title":"The Effects of Group differentiation by students’ learning strategies","authors":"C. Haelermans","doi":"10.1007/s11251-021-09575-0","DOIUrl":"https://doi.org/10.1007/s11251-021-09575-0","url":null,"abstract":"","PeriodicalId":47990,"journal":{"name":"Instructional Science","volume":"50 1","pages":"223 - 250"},"PeriodicalIF":2.5,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49120083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
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