{"title":"Blue Hopes, Red Flags: The Methylene Blue Dilemma in Sepsis Shock.","authors":"Deepak Govil, Anant Vikram Pachisia","doi":"10.5005/jp-journals-10071-24912","DOIUrl":"10.5005/jp-journals-10071-24912","url":null,"abstract":"<p><p><b>How to cite this article:</b> Govil D, Pachisia AV. Blue Hopes, Red Flags: The Methylene Blue Dilemma in Sepsis Shock. Indian J Crit Care Med 2025;29(2):95-97.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"95-97"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rania G Elsayed, Amr F Hafez, Mohammed M Maarouf, Farouk Ke AbdElAziz
{"title":"Impact of the Early Use of High-flow Nasal Cannula in Patients with Post-traumatic Lung Contusion: A Randomized Clinical Trial.","authors":"Rania G Elsayed, Amr F Hafez, Mohammed M Maarouf, Farouk Ke AbdElAziz","doi":"10.5005/jp-journals-10071-24904","DOIUrl":"10.5005/jp-journals-10071-24904","url":null,"abstract":"<p><strong>Background: </strong>Patients with pulmonary contusion (PC) following blunt chest trauma are at risk of developing acute lung injury. High-flow nasal cannula (HFNC) is an established method for managing hypoxic respiratory failure (HRF).</p><p><strong>Aim: </strong>This study aims to evaluate the efficacy of oxygen therapy delivered through HFNC vs venturi mask (VM) in patients with hypoxia following traumatic lung contusion, to reduce the need for intubation and ventilation.</p><p><strong>Materials and methods: </strong>This is an open-label randomized controlled trial conducted on 120 patients with HRF following traumatic PC and a PaO<sub>2</sub>/FiO<sub>2</sub> of 100-200 mm Hg. Patients were divided into two groups: Group A (60 patients) received oxygen therapy through HFNC, while group B (60 patients) received oxygen therapy through VM.</p><p><strong>Results: </strong>High-flow nasal cannula significantly improved pulmonary oxygenation as early as 1 hour after randomization and the after with statistically significant improvement of PaO<sub>2</sub>/FiO<sub>2</sub> over time (<i>p</i> < 0.001). However, it was associated with a nonsignificant reduction in the rate of intubation and mechanical ventilation (<i>p</i> = 0.255) and a nonsignificant reduction in the mortality rate (<i>p</i> = 0.491). The extent of PC was found to be an independent predictor of mortality (<i>p</i> = 0.589) and length of hospital stay (<i>p</i> = 0.581) by multivariate analysis.</p><p><strong>Conclusion: </strong>The early use of HFNC is associated with a significant improvement in pulmonary oxygenation. We suggest that HFNC can be used as a first-line oxygen therapy in hypoxic patients with lung contusion following blunt chest trauma.</p><p><strong>How to cite this article: </strong>Elsayed RG, Hafez AF, Maarouf MM, AbdElAziz FKE. Impact of the Early Use of High-flow Nasal Cannula in Patients with Post-traumatic Lung Contusion: A Randomized Clinical Trial. Indian J Crit Care Med 2025;29(2):117-124.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"117-124"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Braden Score vs APACHE to Predict Occurrence of Bed Sores in a Tertiary Care ICU.","authors":"Khuram Maqbool, Munish Chauhan, Sandeep Dewan","doi":"10.5005/jp-journals-10071-24911","DOIUrl":"10.5005/jp-journals-10071-24911","url":null,"abstract":"<p><strong>Introduction: </strong>Pressure sores, or bedsores, pose a challenge in intensive care unit (ICU) care due to patients' immobility and compromised circulation. This study explores the effectiveness of the Braden Scale and acute physiology and chronic health evaluation II (APACHE II) in predicting pressure sore occurrences.</p><p><strong>Materials and methods: </strong>Conducted over a year in an Indian ICU, this observational study assessed the predictive capability of both scores. Participants (≥18 years) underwent Braden and APACHE II assessments upon admission, with daily monitoring for pressure sore development. Statistical analysis compared scores and ulcer occurrences.</p><p><strong>Results: </strong>Older patients, particularly males, showed a higher tendency for ICU admission. 20.3% had pressure ulcers, significantly correlating with lower Braden and higher APACHE II scores. Acute physiology and chronic health evaluation II showed superior efficiency in predicting ulcers.</p><p><strong>Discussion: </strong>While Braden scores' variability was less in ICU patients, APACHE II scores reflected acute illness severity, strongly correlating with ulcer incidence. The study advocates for a combined utilization of both scores for tailored interventions.</p><p><strong>Conclusion: </strong>Acute physiology and chronic health evaluation II demonstrated better efficiency in predicting pressure ulcers, while the Braden score remains valuable for focused assessments. The study highlights the importance of considering age, gender, acute health status, and localized risk factors in ICU pressure ulcer assessment.</p><p><strong>Future directions: </strong>Further research might explore integrated scoring systems or protocols combining the strengths of both scores for more precise risk assessment in ICU settings.</p><p><strong>How to cite this article: </strong>Maqbool K, Chauhan M, Dewan S. Comparison of Braden Score vs APACHE to Predict Occurrence of Bed Sores in a Tertiary Care ICU. Indian J Crit Care Med 2025;29(2):164-169.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"164-169"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction of Prediction of Weaning Outcome from Mechanical Ventilation Using Ultrasound Assessment of Parasternal Intercostal Muscle Thickness.","authors":"","doi":"10.5005/jp-journals-10071-24921","DOIUrl":"10.5005/jp-journals-10071-24921","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"198"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilization of Local Remedies among Dengue Patients Admitted to the Emergency Department of a Tertiary Care Center: An Observational Study.","authors":"Avichal Rajpal, Ashok Kumar Pannu, Ashish Behera, Navneet Sharma, Mohan Kumar Hanumanthappa","doi":"10.5005/jp-journals-10071-24896","DOIUrl":"10.5005/jp-journals-10071-24896","url":null,"abstract":"<p><strong>Background: </strong>Dengue viral infection (DVI) affects ~ 400 million people annually, with ~ 100 million cases causing clinical illness. Limited therapeutic options often lead patients to adopt alternative remedies. This study evaluates the prevalence and impact of such remedies on outcomes in patients admitted to a tertiary care emergency department.</p><p><strong>Materials and methods: </strong>A single-center, observational study was conducted from July 2022 to September 2023, including 170 patients aged >12 years with severe DVI or DVI with warning signs, as per the World Health Organization (WHO) criteria. The use of local remedies such as goat's milk, papaya leaves/extract, neem leaves, giloy juice, and alternative medicine was documented. Outcomes, including mortality and hospital stay duration, were compared between remedy users and non-users.</p><p><strong>Results: </strong>The mean age of participants was 36 years, with 60% males and 50% from rural areas. 35.29% used local remedies, with goat's milk (23.52%) and papaya leaves/extract (15.29%) being the most common. The median duration of remedy use was 2 days. Mortality was 6.67% in remedy users and 8.4% in non-users (<i>p</i> = 0.28). The median hospital stay was 4 days for both groups, with no significant outcome differences.</p><p><strong>Conclusion: </strong>One-third of DVI patients used local remedies, with goat's milk being the most prevalent. However, no significant impact on mortality or hospital stay was observed.</p><p><strong>How to cite this article: </strong>Rajpal A, Pannu AK, Behera A, Sharma N, Hanumanthappa MK. Utilization of Local Remedies among Dengue Patients Admitted to the Emergency Department of a Tertiary Care Center: An Observational Study. Indian J Crit Care Med 2025;29(2):148-150.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"148-150"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author Response: Balanced Electrolyte Solutions in Diabetic Ketoacidosis: Where does Sterofundin Stand?","authors":"Priyanka Gupta, Prashant Nasa","doi":"10.5005/jp-journals-10071-24911","DOIUrl":"10.5005/jp-journals-10071-24911","url":null,"abstract":"<p><p><b>How to cite this article:</b> Gupta P, Nasa P. Author Response: Balanced Electrolyte Solutions in Diabetic Ketoacidosis: Where does Sterofundin Stand? Indian J Crit Care Med 2025;29(2):196.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"196"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intubation during Uninterrupted Chest Compressions: How Easy?","authors":"Asif Ahmed, Anu Prasad, Sujeet Ashok Joshi","doi":"10.5005/jp-journals-10071-24915","DOIUrl":"10.5005/jp-journals-10071-24915","url":null,"abstract":"<p><p><b>How to cite this article:</b> Ahmed A, Prasad A, Joshi SA. Intubation during Uninterrupted Chest Compressions: How Easy? Indian J Crit Care Med 2025;29(2):98-100.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"98-100"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Balanced Electrolyte Solutions in Diabetic Ketoacidosis: Where does Sterofundin Stand?","authors":"Ashok K Pannu","doi":"10.5005/jp-journals-10071-24903","DOIUrl":"10.5005/jp-journals-10071-24903","url":null,"abstract":"<p><p><b>How to cite this article:</b> Pannu AK. Balanced Electrolyte Solutions in Diabetic Ketoacidosis: Where does Sterofundin Stand? Indian J Crit Care Med 2025;29(2):195.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"195"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sachit Sharma, Hem R Paneru, Gentle S Shrestha, Pramesh S Shrestha, Subhash P Acharya
{"title":"Author Response: Appropriately Designed Studies are Needed before Thiamine and Vitamin C Plus Hydrocortisone are Judged Nonbeneficial in Septic Shock.","authors":"Sachit Sharma, Hem R Paneru, Gentle S Shrestha, Pramesh S Shrestha, Subhash P Acharya","doi":"10.5005/jp-journals-10071-24902","DOIUrl":"10.5005/jp-journals-10071-24902","url":null,"abstract":"<p><p><b>How to cite this article:</b> Sharma S, Paneru HR, Shrestha GS, Shrestha PS, Acharya SP. Author Response: Appropriately Designed Studies are Needed before Thiamine and Vitamin C Plus Hydrocortisone are Judged Nonbeneficial in Septic Shock. Indian J Crit Care Med 2025;29(2):193-194.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"193-194"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Controlling Glycemic Variability in Non-diabetic Sepsis Patients: A Step toward Precision in Critical Care.","authors":"","doi":"10.5005/jp-journals-10071-24909","DOIUrl":"10.5005/jp-journals-10071-24909","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 2","pages":"197"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}