Androloji bülteni最新文献

{"title":"Varikoselli hastalarda sistemik immün enflamasyon endeksi ve hematolojik enflamatuvar parametrelerinin değerlendirilmesi: Kontrollü bir çalışma","authors":"Şaban Oğuz Demirdöğen, Ahmet Emre Cinislioğlu, Tugay Aksakallı, Mehmet Sefa Altay, Adem Utlu, İbrahim Karabulut, İsa Özbey","doi":"10.24898/tandro.2023.34603","DOIUrl":"https://doi.org/10.24898/tandro.2023.34603","url":null,"abstract":"OBJECTIVES: This study aims to evaluate the relationship between varicocele and inflammation using hematological inflammatory parameters in patients with varicocele and systemic immune inflammation (SII) index, and to contribute to the etiopathogenesis of varicocele. MATERIAL and METHODS: The study included 56 healthy volunteers, and 59 patients who were diagnosed to have varicocele in the urology clinics of Erzurum City Hospital between May 2018 and December 2021. Patient files were retrospectively investigated and the data of whole blood analysis were recorded. Parameters obtained from whole blood analysis and systemic immune inflammation index were compared between groups. RESULTS: A total of 59 adult male who have diagnosed as varicocele were included in the patient group and 56 healthy adult volunteers were included in the control group. When the two groups were compared in terms of body mass index and mean age, there was no statistically significant difference. (p=0.915 and p=0.25, respectively). Lymphocyte count was significantly reduced in the patient group (p<0.001). Neutrophil/Lymphocyte ratio (NLR), Monocyte/Lymphocyte ratio (MLR), Platelet/Lymphocyte ratio (PLR) and SII index were found to be significantly higher in the patient group when compared for both groups (p<0.001, p=0.033, p<0.001 and p=0.005, respectively). There was no relation between the grade of varicocele and hematological inflammatory parameters or systemic inflammation index in the patient group. When we examined the relationship between semen parameters and SII index in patients with varicocele, we found that lymphocyte count, neutrophil count, NLR and SII index were significantly higher in patients with abnormal semen parameters compared to patients with normospermic varicocele (respectively; p=0.004, p=0.003, p<0.001 and p<0.001) SII has the best predictive power in predicting Impaired Semen Quality in varicocele patients among inflammatory parameters. CONCLUSION: SII index and hematological inflammatory parameters can show that inflammation is one of the factors playing a role in varicocele pathogenesis. Our study has important results showing the relationship between hematological inflammatory parameters and especially SII index and semen parameters in patients with varicocele. Prospective, randomized studies with larger numbers of patients and control groups should be conducted in order to investigate whether SII index and hematological inflammatory parameters can be used in the diagnosis, follow-up and treatment of varicocele. Keywords: varicocele, inflammation, systemic immune inflammation index","PeriodicalId":472476,"journal":{"name":"Androloji bülteni","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135799177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sünnet muayenesinde saptanan genital anomali oranları: Tek merkezli çalışma","authors":"Kenan Yalçın","doi":"10.24898/tandro.2023.02439","DOIUrl":"https://doi.org/10.24898/tandro.2023.02439","url":null,"abstract":"OBJECTIVES: In this study, we aimed to evaluate the genital organ anomaly rates detected during circumcision examination in the light of the literature. MATERIAL and METHODS: 5427 circumcision operations were performed in our clinic for 11 years. The genital organ anomaly data detected in the circumcision examination were obtained by examining the patient files retrospectively. The obtained data were evaluated in the light of the literature. RESULTS: The number of patients with genital anomalies during a total of 5427 circumcision examinations was 324 (5.97%). The most frequently detected anomalies are respectively; undescended testis (1.47%), intact foreskin megameatus (1.27%), retractile testis (0.88%), hypospadias (0.69%), inguinal hernia (0.68%) and other anomalies (0.98%). CONCLUSION: It was concluded that families should be educated and conscious about the importance of circumcision examination, and physicians should be more careful in circumcision examination. We would like to state that physicians should be more careful about intact foreskin megameatus, which cannot be detected in physical examination and is detected when the circumcision procedure is started. Keywords: anomaly, external genitalia, circumcision, examination","PeriodicalId":472476,"journal":{"name":"Androloji bülteni","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135798661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glanüler tip megameatus intakt sünnet derisi olan olgularda tedavi ne olmalıdır?","authors":"Kenan Yalçın","doi":"10.24898/tandro.2023.48295","DOIUrl":"https://doi.org/10.24898/tandro.2023.48295","url":null,"abstract":"OBJECTIVES: We aimed to evaluate the treatment options in patients with glanular type megameatus intact foreskin. MATERIAL and METHODS: Between 2011 and 2021, more than 5000 circumcision procedures were performed in our clinic. The treatment options of 70 cases with glanular type megameatus, which we encountered incidentally when the foreskin was retracted during the circumcision procedure and sometimes we did not know exactly what to do at that moment, were found to be treated retrospectively. Glans approximation procedure (GAP) was applied to 14 of 24 patients who accepted hypospadias surgery. Meatal advancement and glanuloplasty procedure (MAGPI) was performed in 10 of them. The mean age, duration of surgery and surgical intervention results of the cases were evaluated. RESULTS: The mean age of the patients who underwent the GAP procedure was 4.7±1.9, and the duration of surgery was 59.1±6.3 minutes. Urethral stenosis was seen in 1 of 14 cases and urethral fistula complication was observed in 1 of them. The mean age of the patients who underwent the MAGPI procedure was 4.3±1.4, and the duration of surgery was 64.3±3.03 minutes. Urethral stenosis was seen in 1 of 10 cases and unsuccessful surgical complication was observed in 1 of them. Complications developed in 4 (16.66%) of 24 patients. 4 patients underwent re-operation. There was no significant difference in the mean age, duration of surgery and complication rates between the two techniques. CONCLUSION: Intact foreskin conceals clinical findings and megameatus can usually be detected at circumcision attempt. Although the surgery for the glanular type, which is the mildest form of megameatus, is controversial, satisfactory results can be obtained with the appropriate surgical method. In addition, detailed interviews should be made with families before surgery and it should be explained that the operation is controversial. Keywords: glanular, hypospadias, intact foreskin, megameatus","PeriodicalId":472476,"journal":{"name":"Androloji bülteni","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135798667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}