Reumatologia Clinica最新文献_第5页

Análisis coste/efectivo del diagnóstico de la arteritis de la temporal 颞动脉炎诊断的成本效益分析

IF 1.5

Reumatologia Clinica Pub Date : 2024-04-01 DOI: 10.1016/j.reuma.2023.12.004

Isabel del Blanco Alonso, Álvaro Revilla Calavia, Laura Saiz-Viloria, Manuel Diez Martínez, Enrique San Norberto García, Carlos Vaquero Puerta

{"title":"Análisis coste/efectivo del diagnóstico de la arteritis de la temporal","authors":"Isabel del Blanco Alonso, Álvaro Revilla Calavia, Laura Saiz-Viloria, Manuel Diez Martínez, Enrique San Norberto García, Carlos Vaquero Puerta","doi":"10.1016/j.reuma.2023.12.004","DOIUrl":"10.1016/j.reuma.2023.12.004","url":null,"abstract":"<div><p>Temporal arteritis (TA) is the most common form of systemic vasculitis. Its diagnosis is based on criteria proposed by the American College of Rheumatology (1990), and its treatment is high-dose corticosteroids.</p><p>Our objective is to assess the cost of diagnosing TA, and secondarily, cost-effective analysis of different diagnostic strategies (clinical, biopsy, Doppler ultrasound) and therapeutic strategies (corticosteroid suspension).</p></div><div><h3>Material and method</h3><p>Observational, retrospective study has been carried out on patients with TA (2012–2021). Demographic data, comorbidities, signs and symptoms suggestive of TA were collected. TA was diagnosed with a score ≥3 according to American College of Rheumatoloy criteria (ACR-SCORE). The costs of diagnosis and treatment modification were analysed.</p></div><div><h3>Results</h3><p>Seventy-five patients have been included, median age 77 (46-87) years. Headache, temporal pain and jaw claudication were significant for the diagnosis of TA.</p><p>Patients with a halo on Doppler ultrasound and a positive biopsy have significantly elevated ESR and CRP compared to patients who do not.</p><p>The cost of the TA diagnosis was 414.7 euros/patient. If we use ACR-SCORE≥3-echodoppler it is 167.2 €/patient (savings 59.6%) and ACR-SCORE≥3-biopsy 339.75 €/patient (savings 18%). If the corticosteroid was removed and a biopsy was performed, 21.6 €/patient (94.7% savings), if the corticosteroid was removed and Doppler ultrasound was performed, 10.6 €/patient (97.4% savings).</p></div><div><h3>Conclusions</h3><p>Headache, temporary pain and jaw claudication are predictors of TA. Elevated ESR and CRP are predictors of positive biopsy and presence of halo on ultrasound.</p><p>The uses of ACR-SCORE≥3 with Doppler ultrasound or biopsy, and with corticosteroid suspension, are cost-effective.</p></div>","PeriodicalId":47115,"journal":{"name":"Reumatologia Clinica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139631364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Latin-American rheumatology community needs to put the eye on ocular cicatricial pemphigoid 拉美风湿病学界需要关注眼部卡他性丘疹病

IF 1.5

Reumatologia Clinica Pub Date : 2024-04-01 DOI: 10.1016/j.reuma.2023.09.006

Ariana Ringer , Andrea María Smichowski , José Maximiliano Martínez Pérez , Ignacio Javier Gandino

引用次数: 0

An update on the study of synovial fluid in the geriatric patient 老年患者滑液研究的最新进展

IF 1.5

Reumatologia Clinica Pub Date : 2024-04-01 DOI: 10.1016/j.reuma.2023.12.006

Javier Fernández-Torres , Víctor Ilizaliturri-Sánchez , Karina Martínez-Flores , Carlos Alberto Lozada-Pérez , Rolando Espinosa-Morales , Yessica Zamudio-Cuevas

{"title":"An update on the study of synovial fluid in the geriatric patient","authors":"Javier Fernández-Torres , Víctor Ilizaliturri-Sánchez , Karina Martínez-Flores , Carlos Alberto Lozada-Pérez , Rolando Espinosa-Morales , Yessica Zamudio-Cuevas","doi":"10.1016/j.reuma.2023.12.006","DOIUrl":"https://doi.org/10.1016/j.reuma.2023.12.006","url":null,"abstract":"<div><h3>Background</h3><p>The characteristics of synovial fluid (SF) in geriatric patients differ from those in younger patients. In Mexico, epidemiologic data on the incidence of different rheumatic diseases in geriatric patients are scarce.</p></div><div><h3>Objective</h3><p>To describe the physical characteristics of geriatric SF and the prevalence of crystals in knee and other joint aspirates from patients with previously diagnosed joint disease.</p></div><div><h3>Materials and methods</h3><p>A retrospective study was performed with a baseline of 517 SF samples between 2011 and 2023. White blood cell count was performed by Neubauer chamber and crystals were identified by polarized light microscopy. Descriptive statistical analysis was performed and prevalence was reported as a percentage.</p></div><div><h3>Results</h3><p>The mean age of the adults was 73.5±5.0 years, 54.4% were women and 45.6% were men. The mean SF volume was 6.3±9.5mL in older adults and 15.3±24.9mL in those younger than 65 years. The mean viscosity in older adults was 9.5±4.5mm and the mean leukocyte count was 7352±16,402leukocytes/mm<sup>3</sup>. Seventy percent of the older adults’ SFs were referred to the laboratory for osteoarthritis (OA), with lower proportions for rheumatoid arthritis (RA) (14.6%) and gout (5.1%). Of the crystals observed in the geriatric population, 14.6% corresponded to monosodium urate crystals (CUM) and 18.9% to calcium pyrophosphate crystals (CPP).</p></div><div><h3>Conclusions</h3><p>The characteristics of LS in older adults were smaller volume, increased viscosity, and non-inflammatory. The main diagnoses were OA, RA, and gout. The crystal content of the SF of the geriatric population corresponded mainly to CPP.</p></div>","PeriodicalId":47115,"journal":{"name":"Reumatologia Clinica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140548392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the comparative effect of vitamin D level with the type of complications in Henoch Schönlein purpura and Kawasaki disease 研究维生素 D 水平与白癜风和川崎病并发症类型的比较效应

IF 1.5

Reumatologia Clinica Pub Date : 2024-04-01 DOI: 10.1016/j.reuma.2023.12.007

Mehrnoush Hassas Yeganeh , Reza Sinaei , Mitra Rouhi , Reza Shiari , Vadood Javadi Parvaneh , Khosro Rahmani , Erfan Sheikhbahaei

{"title":"Investigating the comparative effect of vitamin D level with the type of complications in Henoch Schönlein purpura and Kawasaki disease","authors":"Mehrnoush Hassas Yeganeh , Reza Sinaei , Mitra Rouhi , Reza Shiari , Vadood Javadi Parvaneh , Khosro Rahmani , Erfan Sheikhbahaei","doi":"10.1016/j.reuma.2023.12.007","DOIUrl":"10.1016/j.reuma.2023.12.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Henoch Schönlein purpura (HSP) and Kawasaki disease (KD) are two main inflammatory diseases among childhood vasculitis. Considering the anti-inflammatory effects of 25-hydroxyvitamin D3, we decided to investigate the association of serum 25-hydroxy vitamin D3 level with the type and severity of these conditions.</p></div><div><h3>Materials and methods</h3><p>The present study was performed as a historical cohort of 254 affected children with KD and HSP vasculitis. The required data were extracted, using a researcher-made questionnaire from patients’ electronic file, and then they were analyzed after collecting information of the patients.</p></div><div><h3>Results</h3><p>In HSP group, 54% of participants were boys. Similarly, in KD group, boys were more affected than girls. The comparative 25-hydroxyvitamin vitamin D3 level in HSP patients with and without renal involvement (<em>P</em>  =0.14), and in two groups with and without heart disease, and also with and without coronary artery dilatation in KD patients (<em>P</em>  <!-->0.001) were significant.</p></div><div><h3>Discussion and conclusions</h3><p>The findings showed that insufficient level of vitamin D3 were significantly associated with the exacerbation of complications of both diseases, and therefore it seems that vitamin D deficiency can be an effective predictive factor of severity in HSP and KD patients.</p></div>","PeriodicalId":47115,"journal":{"name":"Reumatologia Clinica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140407285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive dysfunction, depression and serum level of brain-derived neurotrophic factor (BDNF) in Egyptian patients with rheumatoid arthritis 埃及类风湿关节炎患者的认知功能障碍、抑郁和血清脑源性神经营养因子 (BDNF) 水平

IF 1.5

Reumatologia Clinica Pub Date : 2024-04-01 DOI: 10.1016/j.reuma.2023.12.003

Mona I. Nabih , Noha M. Khalil , Olfat Shaker , Mahmoud Ghanema , Sarah A. Hassan

{"title":"Cognitive dysfunction, depression and serum level of brain-derived neurotrophic factor (BDNF) in Egyptian patients with rheumatoid arthritis","authors":"Mona I. Nabih , Noha M. Khalil , Olfat Shaker , Mahmoud Ghanema , Sarah A. Hassan","doi":"10.1016/j.reuma.2023.12.003","DOIUrl":"10.1016/j.reuma.2023.12.003","url":null,"abstract":"<div><h3>Aim of the work</h3><p>To evaluate serum brain-derived neurotrophic factor (BDNF) in Egyptian patients with rheumatoid arthritis (RA) and its relation with cognitive dysfunction.</p></div><div><h3>Patients and methods</h3><p><span>The study was carried out on 60 RA patients; 30 were active (group A) and 30 were non active (group B); and 30 controls (group C). RA disease activity was assessed via DAS28 tool, cognitive function via The Montreal Cognitive Assessment and depression via the </span>PHQ<span> depression scale. Serum BDNF levels were measured.</span></p></div><div><h3>Results</h3><p>The mean age in group A was 37.8 (±9.37) years with 83.3% females, in group B was 39.97 (±8.04) years with 86.7% females and in group C was 33.17 (±3.6) years with 93.3% females. Abnormal cognitive functions test was detected in 66.7% of group A, 66.7% of group B, and in 23.3% of group C. There was a statistically significant difference in BDNF serum level between both groups of patients (1.58±0.9ng/ml for group A, 1.81±1.17ng/ml for group B) compared with the control group (3.01±1.25ng/ml, <em>p</em>   <!-->ng/ml, BDNF detected RA patients with cognitive dysfunction with a sensitivity of 80%, specificity of 96.67%.</p></div><div><h3>Conclusion</h3><p>BDNF can be a potential biomarker of cognitive dysfunction in RA patients.</p></div>","PeriodicalId":47115,"journal":{"name":"Reumatologia Clinica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139455356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neumomediastino espontáneo: una manifestación extramuscular de la dermatomiositis anti-MDA5. Reporte de 2 casos 自发性气胸：抗MDA5皮肌炎的一种肌肉外表现。两个病例的报告

IF 1.5

Reumatologia Clinica Pub Date : 2024-04-01 DOI: 10.1016/j.reuma.2023.12.002

Pablo Arango Guerra , Santiago Monsalve Yepes , Andrés Chavarriaga Restrepo , Carlos Jaime Velasquez Franco

引用次数: 0

Epidemiology of thromboembolic events in children and adolescents with antiphospholipid syndrome: A systematic review with meta-analysis 抗磷脂综合征儿童和青少年血栓栓塞事件的流行病学：系统回顾与荟萃分析

IF 1.5

Reumatologia Clinica Pub Date : 2024-02-05 DOI: 10.1016/j.reuma.2023.10.001

Mickael Essouma , Jan Rene Nkeck , Jean Jacques Noubiap

{"title":"Epidemiology of thromboembolic events in children and adolescents with antiphospholipid syndrome: A systematic review with meta-analysis","authors":"Mickael Essouma , Jan Rene Nkeck , Jean Jacques Noubiap","doi":"10.1016/j.reuma.2023.10.001","DOIUrl":"10.1016/j.reuma.2023.10.001","url":null,"abstract":"<div><h3>Background and aim</h3><p>This was a systematic review and meta-analysis of the prevalence of thromboembolic events in children and adolescents with antiphospholipid syndrome (APS).</p></div><div><h3>Methods</h3><p>We searched PubMed, EMBASE and Web of Science to select relevant articles published between 1 January 2000 and 27 February 2022. We used the random-effects meta-analysis to estimate pooled point prevalence rates of thromboembolic events in studies with a minimum sample size of 30.</p></div><div><h3>Results</h3><p>We included five studies reporting data of 336 children and adolescents with primary APS and secondary APS (SAPS). Pooled point prevalence rates of initial general thrombosis, arterial thrombosis, venous thrombosis and stroke in individuals with seropositive APS were 98.2% (95% confidence interval [CI] 87.5–100), 27.6% (95% CI 21.4–34.2), 51.1% (95% CI 38.2–63.9) and 13.4% 95% CI (6.3–22.7), respectively. Pooled point prevalence rates of initial arterial and venous thromboses in children and adolescents with SAPS were 45.7% (95% CI 21.1–71.6) and 29.2% (95% CI 14.8–46), respectively.</p></div><div><h3>Conclusion</h3><p>Arterio-venous thromboembolism is highly frequent in children and adolescents with SAPS. More studies using thrombotic and non-thrombotic APS classification criteria are warranted to better assess the frequency and predictors of thromboembolism in age- and ancestry-diverse pediatric populations affected by different types of APS.</p></div>","PeriodicalId":47115,"journal":{"name":"Reumatologia Clinica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139824958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance of adenosine deaminase in synovial fluid for the diagnosis of tuberculous arthritis: A systematic review and meta-analysis 滑液中腺苷脱氨酶诊断结核性关节炎的性能：系统回顾与荟萃分析

IF 1.5

Reumatologia Clinica Pub Date : 2024-01-18 DOI: 10.1016/j.reuma.2023.11.003

Juan Carlos Cortes-Quiroz, Jose Bernal, Jose Rosas, Javier Ena

{"title":"Performance of adenosine deaminase in synovial fluid for the diagnosis of tuberculous arthritis: A systematic review and meta-analysis","authors":"Juan Carlos Cortes-Quiroz, Jose Bernal, Jose Rosas, Javier Ena","doi":"10.1016/j.reuma.2023.11.003","DOIUrl":"10.1016/j.reuma.2023.11.003","url":null,"abstract":"<div><h3>Objectives</h3><p>Adenosine deaminase (ADA) activity has shown good performance in diagnosing pleural, peritoneal, and meningeal tuberculosis. This meta-analysis aimed to evaluate the performance of measuring ADA activity in synovial fluid for the early diagnosis of joint tuberculosis.</p></div><div><h3>Methods</h3><p><span>We searched published information in MEDLINE, Embase, Cochrane Library, Web of Science, and MedRxiv databases, as well as unpublished information in the American College of Rheumatology and European League Against </span>Rheumatism for conference abstracts (2012–2021). We also scanned the reference lists of articles. Two reviewers independently applied the criteria for selection, assessed quality, and extracted data (PROSPERO number CRD42021284472).</p></div><div><h3>Results</h3><p>Seven independent studies (<em>N</em>  =3; 148 subjects) and low quality (<em>n</em>  =23%) and 88% (95% CI, 83–92; <em>I</em><sup>2</sup>  =30%). The receiver operating characteristic curve area was 0.96 (95% CI, 0.92–0.99). Meta-regression did not identify the quality of the study, country of publication, or the type of assay as a source of heterogeneity.</p></div><div><h3>Conclusions</h3><p>Measuring ADA activity in synovial fluid demonstrates good performance for the early diagnosis of joint tuberculosis.</p></div>","PeriodicalId":47115,"journal":{"name":"Reumatologia Clinica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139633072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilidad de la ecografía reumatológica en la toma de decisiones en la práctica clínica: Estudio unicéntrico longitudinal 风湿病超声波在临床决策中的应用：一项单中心纵向研究。

IF 1.5

Reumatologia Clinica Pub Date : 2024-01-16 DOI: 10.1016/j.reuma.2023.09.007

Marta Serrano-Warleta , Aliuska Palomeque-Vargas , Rosa Manzo , Boris Blanco-Cáceres , Mónica Vazquez-Díaz , Carlos Guillen-Astete

{"title":"Utilidad de la ecografía reumatológica en la toma de decisiones en la práctica clínica: Estudio unicéntrico longitudinal","authors":"Marta Serrano-Warleta , Aliuska Palomeque-Vargas , Rosa Manzo , Boris Blanco-Cáceres , Mónica Vazquez-Díaz , Carlos Guillen-Astete","doi":"10.1016/j.reuma.2023.09.007","DOIUrl":"10.1016/j.reuma.2023.09.007","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of the present study is to identify the extent to which rheumatological musculoskeletal ultrasound affects clinical decisions in a single-centre observational retrospective study.</p></div><div><h3>Method</h3><p>The results of 801 requests and 1174 consecutive individual ultrasound examinations performed over 10 months were analysed.</p></div><div><h3>Results</h3><p>The most frequent indication was diagnostic assistance (39%) followed by assessment of inflammatory activity (34%). By topography, the hand was the most frequently studied region (51%), followed by the foot (18.1%). Of all requests, 67% had an impact on decision-making. The impact on clinical decision-making was associated with a shorter waiting time for the evaluation of the results, being the greatest in those ultrasound scans performed on demand on the same day of the request. In 73% of bilateral ultrasound studies, findings in one of the joints exemplified the overall result reported.</p></div><div><h3>Conclusions</h3><p>Rheumatological musculoskeletal ultrasound has proven to be a useful decision-making technique, the greater the impact of which is seen the shorter the waiting time before it is performed.</p></div>","PeriodicalId":47115,"journal":{"name":"Reumatologia Clinica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139631970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of combined treatment with prednisone and methotrexate versus prednisone alone over laboratory parameters in giant cell arteritis 泼尼松和甲氨蝶呤联合治疗与泼尼松单独治疗对巨细胞动脉炎实验室指标的影响

IF 1.5

Reumatologia Clinica Pub Date : 2024-01-12 DOI: 10.1016/j.reuma.2023.09.011

Ines Perez-Sancristobal , Paula Alvarez-Hernandez , Cristina Lajas-Petisco , Benjamin Fernandez-Gutierrez

{"title":"Effect of combined treatment with prednisone and methotrexate versus prednisone alone over laboratory parameters in giant cell arteritis","authors":"Ines Perez-Sancristobal , Paula Alvarez-Hernandez , Cristina Lajas-Petisco , Benjamin Fernandez-Gutierrez","doi":"10.1016/j.reuma.2023.09.011","DOIUrl":"https://doi.org/10.1016/j.reuma.2023.09.011","url":null,"abstract":"<div><h3>Objective</h3><p>To compare the effect of combined treatment with prednisone and methotrexate (MTX) versus prednisone alone over laboratory parameters in giant cell arteritis (GCA).</p></div><div><h3>Patients and methods</h3><p><span>We performed a double-blind, placebo-controlled, randomized clinical trial about usefulness of treatment with prednisone and MTX versus prednisone and placebo in GCA (Ann Intern Med 2001;134:106–114). As a part of follow-up of patients (</span><em>n</em>  =0.0002). No significant differences were observed in ESR during relapses. The mean ESR value followed a parallel course in both groups, but was lower in the group with MTX than in the group with placebo in 18 of 20 time points of follow-up. The AUC of ESR by time of follow-up was 28,461.7±12,326 in the group with placebo and 19,598.4±8,117 in the group with MTX (mean difference 8,863, 95% CI 1.542–16.184; <em>P</em>  <!-->0.019). The course of other laboratory parameters paralleled, without statistical significance, those observed for ESR.</p></div><div><h3>Conclusions</h3><p>These data, along with clinical data, suggest that MTX might play a role as a disease-modifying agent in the treatment of GCA.</p></div>","PeriodicalId":47115,"journal":{"name":"Reumatologia Clinica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139473207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0