{"title":"Lassa Fever: A Mini Review of Clinical Features, Diagnosis and Treatment","authors":"Ubogun Ogheneakpobor Efe, Efeisi Oreva Edward, Adigwe Augustina Chinaza, Okobah Chidinma Emmanuella, Ntugba Joy Chidinma","doi":"10.9734/ajrid/2024/v15i8363","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i8363","url":null,"abstract":"Lassa virus (LASV) is an enveloped single stranded RNA virus that results in Lassa fever (LF). The causative organism belongs to the Arenavirus genus. Since it's initial diagnosis in 1969 in Lassa town Nigeria, numerous endemic outbreaks have occurred with spread to other regions in Africa and beyond. LF is transmitted via rodent to human and human-to-human transmissions, with rodents being the reservoir of infection. Risk factors for the disease include residing in an endemic area with poor sanitation and overcrowding, close contact with infected individuals and being a health care worker. About 80% of infected patients do not develop symptoms but the remaining develop a multisystem disease, where up to 15% die in-hospital care with its hallmark symptom being bleeding especially from body orifices. This review will introduce a general overview of Lassa fever and describe the epidemiology, clinical features, diagnosis and treatment of Lassa fever patients. It will also provide a means to raise awareness among healthcare workers. Furthermore, our review focuses on the most up-to-date clinical information for the effective management, prevention and counseling of Lassa fever patients.","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"5 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141813943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jamal M. S. Al-khulidi, Mohammed A. Al-Taj, Ashwaq Ahmed Abdullah
{"title":"Seroprevalence of Hepatitis B Virus among Blood Donors at National Blood Transfusion and Research Center-Taiz Branch, Yemen","authors":"Jamal M. S. Al-khulidi, Mohammed A. Al-Taj, Ashwaq Ahmed Abdullah","doi":"10.9734/ajrid/2024/v15i8362","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i8362","url":null,"abstract":"Hepatitis B Virus (HBV) represents one of the most health problems. Almost more than 350 million infected persons were reported universally. Blood transfusion is commonly the most common route of transmission of HBV. Recently, Hospitals in Yemen are increasing demands for blood and blood products due to war injury, anemia, and malnutrition. The risk of transfusion transmission of infection relatively increases. This study aimed to determine hepatitis B virus prevalence among blood donors at the National Blood Transfusion Center -Taiz branch (NBTRC- TB). Data was collected from the National Blood Transfusion and Research Center (Taiz branch) from 1/4/2020 to 16/12/2020. A total of 3174 blood donors donated blood at the center. A descriptive cross-sectional study was conducted on them. Blood donor information was registered at the reception department, and all blood screening tests were performed. Data of HBsAg and total anti-HBc were analyzed statistically by using IBM SPSS version 26. Among 3174 blood donors, male blood donors were 3158 (99.5%) and female blood donors 16 (0.5%). Furthermore, 41 (1.3%) were positive for HBsAg (which all the positive results were for male donors and no positivity were for female donors) while 353 (11.1%) were positive for total anti- HBc Ab which is distributed at ratio of 11% (350) for males and 0.1% (3) for females. On the other hand, the result of HBsAg and total anti-HBc Ab together showed three levels of positivity as the (HBsAg positive / anti-HBc negative) were 12 (0.4%) in which was a low percentage and reversely, the (HBsAg negative/ HBcAb positive) were 316 (10.2%), While the HBsAg positive / anti-HBc positive were 27 (0.9%). So this study shed light on the result of HBsAg negative/ anti-HBc positive which the percentage (10.2%) of which statistically significant (p. value = 0.000) and was the highest result indicates donors with post HBV infection or have low HBV infection. This study showed the high prevalence of post-HBV infection among blood donors. Using both markers HBsAg and total anti-HBc Ab will improve the detection of HBV before blood transfusion.","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"22 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141815957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oluwadamilare Afolabi Obe, Adewunmi Akingbola, B. Mutiu, Margaret Nnakwue, Ibrahim Oladipupo Odulate
{"title":"High Prevalence and Antibiotic Resistance of MRSA and Acinetobacter spp. among Healthcare Personnel and Neonatal Units: Implications for Infection Control and Hygiene Protocols","authors":"Oluwadamilare Afolabi Obe, Adewunmi Akingbola, B. Mutiu, Margaret Nnakwue, Ibrahim Oladipupo Odulate","doi":"10.9734/ajrid/2024/v15i7357","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i7357","url":null,"abstract":" \u0000Objective: To assess the efficacy of current hygiene practices at the tertiary center through comprehensive microbiological surveillance, and to provide targeted recommendations for enhancing hospital hygiene to mitigate infection risks. \u0000Methodology: A cross-sectional study employing microbiological surveillance to evaluate microbial contamination across various hospital settings in a tertiary healthcare facility in Lagos, Nigeria, focusing on high-risk areas such as personnel body parts, operating theaters, specialized care units, and staff areas. The study involved collecting microbial samples from the hospital environment, including surfaces in operating theaters, neonatal units, and healthcare personnel. \u0000Microbial samples were collected from 38 different locations and personnel within the hospital. Culturing was conducted on appropriate media. Antibiotic susceptibility was tested using the disc diffusion method. Statistical analyses included ANOVA and logistic regression to determine the prevalence and distribution of microbial contaminants and to assess the effectiveness of current hygiene practices. \u0000Results: The surveillance detected microbial growth in 33.33% of samples, with significant pathogens like MRSA and Acinetobacter species present. ANOVA showed significant differences in microbial contamination among different hospital locations (F(3,32) = 4.267, p = 0.0121). Logistic regression analysis didn’t find statistically significant predictors for microbial presence but highlighted higher odds of contamination in personnel areas (OR = 2.78, p = 0.406). \u0000Conclusion: The study highlights the need for continuous microbiological surveillance to identify and mitigate infection risks in hospital settings. Despite effective sterilization practices in some areas, the presence of pathogens like MRSA indicates the necessity for enhanced hygiene protocols, particularly in personnel areas.","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"42 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141345077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Rangar, Mahamat Ali Bolti, Ahmet Abdulaye, Dieudonne Dlinga, Yusra Aboulbachar, Oumar Abba, Choua Ouchemi, Ali Mahamat Moussa
{"title":"Epidemiological and Clinical Insights into Pulmonary Tuberculosis among Diabetic Patients: A Descriptive Retrospective Study in N'Djamena, Chad","authors":"N. Rangar, Mahamat Ali Bolti, Ahmet Abdulaye, Dieudonne Dlinga, Yusra Aboulbachar, Oumar Abba, Choua Ouchemi, Ali Mahamat Moussa","doi":"10.9734/ajrid/2024/v15i7356","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i7356","url":null,"abstract":"Introduction: association with HIV tuberculosis is a real public health problem according the International Union Against Tuberculosis and Lung Disease. The objective of this work is to study the epidemiological, progressive and therapeutic aspects of pulmonary tuberculosis in diabetic. \u0000Methods: This is a descriptive retrospective study evaluating the association between pulmonary tuberculosis and diabetes in the pneumo-phtisiology department of the Reference National University Hospital Center over a period of 3 years about 51 cases. \u0000Results: During our study period, we collected 51 cases of pulmonary tuberculosis and diabetes out of a total of all hospitalised patients. with a prevalence of Tuberculosis/Diabetes co-infection of 5.6%. The sex ratio was 2.18 in favour of men. The average age was 52.3 ±13.8 years with extrems ranging from 20 to 80 years old. The notion of tuberculosis infection was found in 21.6% of cases. Other comorbidities were present, such as hypertension (41.2%, n=21) and HIV (15.7%, n=8). The GenXpert results revealed MTB Detected in 62.7% of cases with 9 cases of Rifampicin Resistance Detected. The type of diabetes found was mainly Type 2 diabetes (88.2%) and the most common complication was diabetic foot. The treatment consisted of a quadruple therapy, Oral Antidiabetic (OAD) and insulin, or a combination of both. \u0000Conclusion: This study shows that the association of tuberculosis and diabetes is a reality in our countries. The prevalence remains relatively high and the treatment regimen remains the same. Prevention of TB and correct management of diabetes could reduce the prevalence of this pandemic.","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"28 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141346111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ravi Talapa, Nidhi Yadav, Siddhant Jain, Tanvi Sirohi, Shourya Yerramareddy
{"title":"Thyroid Tuberculosis: A Unique Case Report","authors":"Ravi Talapa, Nidhi Yadav, Siddhant Jain, Tanvi Sirohi, Shourya Yerramareddy","doi":"10.9734/ajrid/2024/v15i6352","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i6352","url":null,"abstract":"Tuberculosis affecting the thyroid gland is a rare occurrence, even in the regions where tuberculosis is prevalent. This case report details the presentation of a 22-year-old male who initially presented with a life-threatening condition of cardiac tamponade, ultimately diagnosed as thyroid tuberculosis. The case underscores the critical role of fine needle aspiration cytology (FNAC) in accurately diagnosing such uncommon manifestations of tuberculosis. This case highlights the significance of FNAC in confirming tuberculosis as the underlying cause of thyroid involvement, facilitating timely and targeted therapeutic interventions for patients presenting with unusual clinical manifestations of tuberculosis.","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"1 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141112798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expert Opinion on the Prescription Practice of Carbapenem Antibiotics for the Treatment of Drug-Resistant Bacterial Infections in Indian Settings","authors":"M. S, Krishna Kumar M","doi":"10.9734/ajrid/2024/v15i3335","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i3335","url":null,"abstract":"Objective: The current survey-based study aims to gather expert opinions on the prescription practice of carbapenem antibiotics for the treatment of drug-resistant bacterial infections in Indian clinical settings. \u0000Methods: The cross-sectional, multiple-response questionnaire-based survey involving professionals with expertise in treating pathogenic illnesses was carried out between 2022 and 2023. The questionnaire comprised 25 questions, the majority of which dealt with the use of antibiotics as monotherapy and in various combinations to treat pathogenic illnesses. \u0000Results: Out of 302 survey participants, 83% of them preferred meropenem medications more frequently than imipenem, biapenem, doripenem, and other antibiotics to treat pathogenic infections. For the management of multidrug-resistant (MDR), extensively drug-resistant (XDR), or pan-drug-resistant (PDR) infections, approximately 54% of the respondents preferred the administration of 1 gm of IV meropenem in 2 to 3 divided doses. About 61% of the responders suggested using IV meropenem together with colistin to treat infections. The combination of IV meropenem with β-lactams, aminoglycosides, tigecycline, colistin, and others was preferred by 91% of the respondents for the treatment of MDR, XDR, and PDR infections. For treating difficult intra-abdominal infections, meningitis, and urinary tract infections (UTIs), almost 43% of the respondents preferred meropenem in combination with sulbactam. \u0000Conclusion: The survey findings emphasize the prominent role of meropenem, either as a standalone treatment or in combination with other antibiotics in the management of challenging infections caused by MDR, XDR, or PDR pathogens. In specific scenarios involving difficult intra-abdominal infections, meningitis, and UTIs, clinicians recommended meropenem in combination with sulbactam antibiotics.","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"108 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140379594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daouda Thioub, Ndèye Amy Sarr, Christine Amengo Kogwapa, Khardiata Diallo Mbaye, Ndeye Aissatou Lakhe, A. S. Badiane, Daye Ka, N. Fall, V. M. P. Cisse, Moussa Seydi
{"title":"Pulmonary Involvement during Varicella in a Patient with Sickle Cell Disease: Diagnosis and Treatment","authors":"Daouda Thioub, Ndèye Amy Sarr, Christine Amengo Kogwapa, Khardiata Diallo Mbaye, Ndeye Aissatou Lakhe, A. S. Badiane, Daye Ka, N. Fall, V. M. P. Cisse, Moussa Seydi","doi":"10.9734/ajrid/2024/v15i2329","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i2329","url":null,"abstract":"Introduction: Pulmonary involvement during chickenpox is one of the most serious complications. However, it can be difficult to distinguish between varicella pneumonia, bacterial superinfection and an acute chest syndrome. We report a case of varicella complicated by pneumonia in a young adult with sickle cell disease. \u0000Observation: It was a 24-year-old woman with sickle cell disease. Examination on admission revealed generalized skin lesions of varying ages, associated with scratching lesions. On day 3 of hospitalization, she presented an acute respiratory distress associated with fever (40°C). Thoracic CT angiography revealed diffuse pulmonary nodules and micronodules in both lung fields. Blood culture isolated Staphylococcus spp. The patient was put on oxygen therapy combined with antiviral treatment and antibiotic therapy. The course was marked by symptoms regression, with disappearance of respiratory distress on day 2 and apyrexia on day 3 of treatment. The follow-up chest CT scan carried out at month 4, came back normal. \u0000Conclusion: Although pneumonia is one of the most common complications of varicella, it can be difficult to diagnose in patients with sickle cell disease, considering the frequency of pulmonary involvement of various etiologies","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"131 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140423856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Sulistyawati, Herman Yuliansyah, Tri Wahyuni Sukesi, Fanani Arief Ghozali, Surahma Asti Mulasari, Fatwa Tentama, B. Sudarsono, Lu'lu' Nafiati, Nuri Hastuti
{"title":"Knowledge, Attitudes, and Behavior of Students in Combating Mosquito Nest: A Case Study in High School","authors":"S. Sulistyawati, Herman Yuliansyah, Tri Wahyuni Sukesi, Fanani Arief Ghozali, Surahma Asti Mulasari, Fatwa Tentama, B. Sudarsono, Lu'lu' Nafiati, Nuri Hastuti","doi":"10.9734/ajrid/2024/v15i2328","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i2328","url":null,"abstract":"Aim: Assessing the relationship between high school student knowledge, attitudes, and behavior of students in eliminating mosquitoes. \u0000Study Design: This research employed a cross-sectional design with participant all students in Binatama Vocational Health School, Sleman, Yogyakarta. \u0000Place and Duration of Study: This research was done at Binatama Health Vocational School, Sleman, Yogyakarta, in November 2023. \u0000Methodology: Quantitative research with a cross-sectional design was employed. The population and sample in this study were all from Binamata Vocational High School (311 students). An online questionnaire was used to collect the students' responses. \u0000Results: A relationship exists between students' knowledge and behavior in eliminating mosquito nests. \u0000Conclusion: The results of this study indicate no significant relationship exists between knowledge and high school students’ attitudes regarding the elimination of mosquito nests. There is a relationship between the knowledge and behavior of high schools in eliminating mosquito nests.","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"53 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140434039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alassane Dièye, Arona Diouf, P. Diouf, Moustapha Diedhiou, M. Diakhaby, Demba Makalou, Samba Niang, Diatou Dia-Gueye, Amadou Diop Dia, I. Dieng, Ahmeth Dieng, Seynabou Lô, N. M. Dia-Badiane
{"title":"SARS-CoV-2 Infection and Factors Associated with Mortality in Hospitalized Patients Aged 60 and Over at the Epidemic Treatment Center (ETC) of Saint-Louis (Senegal)","authors":"Alassane Dièye, Arona Diouf, P. Diouf, Moustapha Diedhiou, M. Diakhaby, Demba Makalou, Samba Niang, Diatou Dia-Gueye, Amadou Diop Dia, I. Dieng, Ahmeth Dieng, Seynabou Lô, N. M. Dia-Badiane","doi":"10.9734/ajrid/2024/v15i2327","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i2327","url":null,"abstract":"Background: SARS-CoV-2 infection typically causes severe pneumonia in elderly patients with high mortality rates. \u0000Aim: This study aimed to describe the epidemiological, clinical, paraclinical and evolution profile of the SARS-CoV-2 infection in patients aged 60 years and over hospitalized at the Epidemic Treatment Center (ETC) of Saint-Louis “Senegal”, and to identify the factors associated with death. \u0000Methodology: This is a cross-sectional, retrospective, descriptive and analytical study conducted from March 2020 to August 2021. It includes all patients aged 60 years and older hospitalized at the ETC of Saint-Louis (Senegal) for SARS-CoV-2 infection. Microsoft Excel was used to enter data and then analysis was done using EPI INFO version 7 software. \u0000Results: Of a total of 448 hospitalizations, 188 patient records aged 60 years and older was collected. The prevalence was 42%. The mean age was 70 years (±8 years). The sex ratio was 1.7 with a male predominance (62.8%). Hypertension was the most common co-morbidity (67%). Severe forms were predominant (64.4%). Dyspnea (60.3%), cough (56.5%) and ageusia (24.5%) were the most common symptoms on admission. Thoracic CT scans showed severe involvement in 51.7% of cases. Hydroxychloroquine-azithromycin combination was prescribed in 98.4% of cases. The mortality rate was 18.6%. The main factors associated with death were age (≤75 years) (p=0.014) [OR=0.488; 95% CI: 0.201-1.187]; critical forms (p=0.017) [OR=0.061; 95% CI: 0.006-0.601]; comorbidity (p=0. 031) [OR=1.647; 95% CI: 0.280-2.499]; occurrence of complications (p=0.009) [OR=1.212; 95% CI: 0.530-2.774]; and SpO2≤95% at admission (p=0.031) [OR=4.899; 95% CI: 0.752-8.797]. \u0000Conclusion: SARS-CoV-2 infection in the elderly is predominantly severe with high mortality. This high-risk group requires special attention.","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"19 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140435511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determinants of Adherence to Antiretroviral Therapy in People Living with HIV, Followed up at Lubumbashi, Democratic Republic of Congo","authors":"Yumba Numbi Georges, Matanda Kapend Serge, Sarr Catherine, Kamalo Mwad Kon Berthe, Kisoka Kimbungu Thierry, Ndua Tshijik Jenny, Mutombo Tshibang Patrick, Bakona Ilunga Dubois, Kapend A Kalal Lievin, Mwamba Mulumba Claude","doi":"10.9734/ajrid/2024/v15i2326","DOIUrl":"https://doi.org/10.9734/ajrid/2024/v15i2326","url":null,"abstract":"Aims: The aim of the present study was to determine the level of adherence and the factors associated with good adherence to antiretroviral treatment (ART) among people living with HIV (PLHIV). \u0000Study Design: Cross Sectional Study. \u0000Place and Duration of Study: Internal medicine department (Infectious Diseases Unit), Lubumbashi University Clinics, in Democratic Republic of Congo (DRC), between 15th May 2021 and 17th July 2021. \u0000Methodology: We included 137 patients (56 men, 81 women; age range 18-70 years) with HIV and, all participants were interviewed on a first-come, first-served basis. The association between factors affecting adherence and the level of adherence was analyzed using a multiple logistic regression model, and odds ratios (ORs) with 95% confidence intervals (CIs) calculated. Among 137 PLHIV, 76.64% had good ART adherence (≥95%). Bivariate analysis revealed numerous factors associated with adherence (P = 0.05). However, in multivariate analysis, being on ART for more than three years and abstinence from alcohol were the factors influencing good ART adherence (P = 0.05). \u0000Results: Among 137 PLHIV, 76.64% had good ART adherence (≥95%). Bivariate analysis revealed numerous factors associated with adherence (P = .05). However, in multivariate analysis, being on ART for more than three years and abstinence from alcohol were the factors influencing good ART adherence (P = .05). \u0000Conclusion: Raising awareness among PLHIV, regular counseling of patients regarding daily intake of antiretroviral drugs and abstinence from alcohol, could contribute to good adherence and long-term success of ART among PLHIV.","PeriodicalId":470403,"journal":{"name":"Asian Journal of Research in Infectious Diseases","volume":"12 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140442077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}