Applied Magnetic Resonance最新文献

The Applicability of NMR Spectroscopy in the Determination of Structures Containing a Fragment of Spiro[1-Azabicyclo[3.3.0]octane] 核磁共振波谱法测定含螺[1-阿扎比环[3.3.0]辛烷]片段结构的适用性

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-08-22 DOI: 10.1007/s00723-025-01780-1

Yulia A. Pronina, Alexander V. Stepakov, Ekaterina V. Berezhnaya, Vitali M. Boitsov, Ruslan I. Baichurin, Stanislav I. Selivanov

{"title":"The Applicability of NMR Spectroscopy in the Determination of Structures Containing a Fragment of Spiro[1-Azabicyclo[3.3.0]octane]","authors":"Yulia A. Pronina, Alexander V. Stepakov, Ekaterina V. Berezhnaya, Vitali M. Boitsov, Ruslan I. Baichurin, Stanislav I. Selivanov","doi":"10.1007/s00723-025-01780-1","DOIUrl":"10.1007/s00723-025-01780-1","url":null,"abstract":"<div>Structures of two new spiro-adducts synthesized on the basis of [3 + 2]-cycloaddition reaction of stable azomethine ylide with styrene and 2,3-dihydrofuran, respectively, were defined by NMR methods. Complete signal assignments in 1H spectra of both compounds were obtained on base analysis of COSY and NOESY experiments by determination of scalar networks in the first case and spatial interactions in the second one, respectively. The identification of aromatic proton signals of indan-1.3-dione fragment was made on base registration of long-range NOEs between them and aliphatic protons which are located at the distances up to 6 angstroms. These proton assignments were helpful for the identification of carbon signals in 13C NMR spectra of compounds under study which were performed by combination of HSQC and HMBC data. Thus, the results of the consistent use of homonuclear (COSY, NOESY) and heteronuclear (HSQC, HMBC) allowed us to make a complete and unambiguous NMR description of two new spiro-adducts and prove their belonging to one of the four synthetically possible regioisomers: (2'SR,7a'RS)-2'-phenyl-1',2',5',6',7',7a'-hexahydrospiro[indene-2,3'-pyrrolizine]-1,3-dione) and (3aSR,3bSR,8aSR)-2,3,3a,3b,4,5,6,8a-octahydrospiro[furo[3,2-a]pyrrolizine-8,2'-indene]-1',3'-dione). The possibility of the existence of the second regioisomer in solution in the form of a fast (in the NMR time-scale) conformational exchange associated with pseudo-rotation around the CH2–CH2 bond in the ethane fragment of the oxygen-containing five-membered ring was detected.</div>","PeriodicalId":469,"journal":{"name":"Applied Magnetic Resonance","volume":"56 8","pages":"937 - 953"},"PeriodicalIF":1.1,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144909876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accurate NMR Diffusion Measurements of Reacting Systems 反应系统的精确核磁共振扩散测量

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-08-18 DOI: 10.1007/s00723-025-01779-8

William S. Price

引用次数: 0

Proton MRD Profile Analysis in Human Serum Albumin Solutions: Two and Three Sites Exchange Model Approaches 人血清白蛋白溶液中的质子MRD谱分析：两个和三个位点交换模型方法

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-08-11 DOI: 10.1007/s00723-025-01785-w

Néstor Juan Rodríguez de la Cruz, Carlos Alberto Cabal Mirabal, Robert N. Müller, Sophie Laurent, Fabian Tamayo Delgado, Juan Carlos García Naranjo, Yasser Rodríguez de la Cruz, Manuel Arsenio Lores Guevara

{"title":"Proton MRD Profile Analysis in Human Serum Albumin Solutions: Two and Three Sites Exchange Model Approaches","authors":"Néstor Juan Rodríguez de la Cruz, Carlos Alberto Cabal Mirabal, Robert N. Müller, Sophie Laurent, Fabian Tamayo Delgado, Juan Carlos García Naranjo, Yasser Rodríguez de la Cruz, Manuel Arsenio Lores Guevara","doi":"10.1007/s00723-025-01785-w","DOIUrl":"10.1007/s00723-025-01785-w","url":null,"abstract":"<div>The two sites water exchange model (2SWEM) and the three sites exchange model (3SEM) were properly used to describe proton (1H) magnetic relaxation dispersion (1HMRD) in human serum albumin (HSA) solutions at 310 K. Lyophilized HSA was obtained from Sigma-Aldrich and diluted in phosphate buffered saline (PBS, pH 7.4) to obtain 10 samples with a concentration of 50 g/l. The 1HMRD profiles (20–60 MHz) were obtained using a fast field cycling nuclear magnetic resonance relaxometry facility (Stelar FFC 2000 Spinmaster) and two Minispec (Mq20, Mq60) relaxometry facilities from Bruker. The longitudinal 1H magnetic relaxation time (T1) was measured employing the inversion recovery pulse sequence and the 1/T1 was plotted as a function of the frequency of resonance to create the 1HMRD profiles. The 2 sites water exchange model considering ellipsoidal geometry is the best option to fit the 1HMRD profiles in diluted HSA solutions, which allows to update the physical model previously presented to describe the theoretical dependence between the transverse proton magnetic relaxation rate and the protein dynamic viscosity in blood plasma and blood serum solutions. The physical parameters obtained from the fit, using this model, describe properly the diluted HSA solutions in comparison with previous experimental reports and theoretical estimations. This result can be improved taking into consideration all the proton–proton dipolar interactions of the protons belonging to the bound water molecules.</div>","PeriodicalId":469,"journal":{"name":"Applied Magnetic Resonance","volume":"56 8","pages":"921 - 935"},"PeriodicalIF":1.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144909821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

1H NMR Relaxation and NOESY in l-Tyrosine in the Presence of Gold Nanoparticles of Different Shapes 不同形状金纳米粒子存在下l-酪氨酸的1H NMR弛豫和NOESY

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-08-11 DOI: 10.1007/s00723-025-01781-0

Galina Kupriyanova, Mark Smirnov, Andrey Zyubin, Aleksander Zozulya, Ivan Lyatun

{"title":"1H NMR Relaxation and NOESY in l-Tyrosine in the Presence of Gold Nanoparticles of Different Shapes","authors":"Galina Kupriyanova, Mark Smirnov, Andrey Zyubin, Aleksander Zozulya, Ivan Lyatun","doi":"10.1007/s00723-025-01781-0","DOIUrl":"10.1007/s00723-025-01781-0","url":null,"abstract":"<div>In this work, we investigate the effect of gold nanoparticles of different shapes on the structural and dynamic properties of l-tyrosine in aqueous solution. Using 1H NMR spectroscopy, NOESY, and 1H NMR relaxation methods, we studied the interactions between l-tyrosine and gold nanoparticles of spherical shaped, star shaped, and rod shaped focusing on their effects on the molecular conformation. Particular attention was paid to the extent to which particles of different shapes affect the structural and dynamic properties of the l-tyrosine molecule. Based on the 1H NMR spectroscopy data, T1 relaxation studies, and NOESY cross-peak intensities, we conclude that gold nanoparticles of different shapes exert diverse effects on conformational behavior of the l-tyrosine in aqueous solution. Different changes in interproton distances were found depending on the nanoparticle shape. The presence of nanoparticles in an aqueous l-tyrosine solution induces a reorientation of the –CH2–CH–COOH chain relative to the aromatic ring. Understanding the processes of conformational changes in AST under the influence of AuNPs, as well as the role of their functional groups binding to AuNPs, has important practical applications for the development of therapeutic agents against Alzheimer’s and Parkinson’s and cardiovascular deceases, associated with aggregation processes and its inhibition.</div>","PeriodicalId":469,"journal":{"name":"Applied Magnetic Resonance","volume":"56 8","pages":"967 - 984"},"PeriodicalIF":1.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144909805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Some Relevant Aspects of Magnetic Resonance and Its Applications 磁共振的一些相关方面及其应用

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-08-09 DOI: 10.1007/s00723-025-01790-z

V. I. Chizhik, M. S. Tagirov

引用次数: 0

Precession Phase Redistribution at Bose Condensation of Magnons 磁振子玻色凝聚的进动相重分布

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-08-06 DOI: 10.1007/s00723-025-01782-z

Yu. M. Bunkov, I. V. Golyshev, G. A. Knyazev, A. N. Kuzmichev, D. A. Samodelkin, P. M. Vetoshko

{"title":"Precession Phase Redistribution at Bose Condensation of Magnons","authors":"Yu. M. Bunkov, I. V. Golyshev, G. A. Knyazev, A. N. Kuzmichev, D. A. Samodelkin, P. M. Vetoshko","doi":"10.1007/s00723-025-01782-z","DOIUrl":"10.1007/s00723-025-01782-z","url":null,"abstract":"<div>Quantum magnonics is an emerging field of research with great potential for applications in quantum technologies, including quantum computing, information processing, and coding. Of particular interest is magnon Bose–Einstein condensation, which can occur even at room temperature due to the small mass of magnons and their weak interaction even at high concentrations. The article describes unique experimental results obtained in the study of the phase transition from magnon gas to Bose condensation with increasing magnon density. It is shown that the properties of a magnon gas are well described by the quasi-classical Landau–Lifshitz–Gilbert equations. However, upon transition to the quantum state of Bose–Einstein condensation, the properties of magnetization precession change dramatically. Instead of spin waves formation outside of the magnon generation region, coherent precession of magnetization occurs. In this paper, attention is drawn for the first time to the change in the direction of phase gradients at the boundary of the magnon excitation region and an explanation of this effect is given. The experiments were carried out in a Yttrium Iron Garnet film under the continuous RF pumping.</div>","PeriodicalId":469,"journal":{"name":"Applied Magnetic Resonance","volume":"56 8","pages":"1063 - 1072"},"PeriodicalIF":1.1,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144909686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wireless Coils in Water and Fluorocarbon Fluid 水和氟碳流体中的无线线圈

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-07-25 DOI: 10.1007/s00723-025-01778-9

Nikolay V. Anisimov, Mikhail V. Gulyaev, Pavel M. Tikhonov, Anna A. Hurshkainen, Olga S. Pavlova

{"title":"Wireless Coils in Water and Fluorocarbon Fluid","authors":"Nikolay V. Anisimov, Mikhail V. Gulyaev, Pavel M. Tikhonov, Anna A. Hurshkainen, Olga S. Pavlova","doi":"10.1007/s00723-025-01778-9","DOIUrl":"10.1007/s00723-025-01778-9","url":null,"abstract":"<div>The paper describes magnetic resonance imaging (MRI) experiments using different types of wireless coils, including solenoid, multi-turn loop, metamaterial-inspired coils (MMI), and transmission line resonators (TLR). Their performance is compared in terms of MR signal amplification inside and near the coils when placed in various mediums—air, water, and fluorocarbon (FC) fluid. Water and FC fluid serve as imaging media for constructing sensitivity maps using 1H and 1⁹F MRI. The sensitivity maps obtained by immersing the coils in FC fluid can be used to calculate corresponding maps for the same coils in air, as well as for coils redesigned to detect 1H signals. It is demonstrated that a resonant circuit based on a solenoid or multi-turn loop may not require lumped capacitance when the coil is immersed in water. In such cases, the coil's self-capacitance (inter-turn capacitance) can fulfill this role, increasing by a factor of 80 upon immersion in water. Additionally, examples are provided for using wireless coils to image living organisms as well as objects that do not produce an NMR signal, employing the signal void imaging approach.</div>","PeriodicalId":469,"journal":{"name":"Applied Magnetic Resonance","volume":"56 8","pages":"909 - 920"},"PeriodicalIF":1.1,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144909742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NMR Studies of Lys-2His Peptide Dendrimers Complexes with C60 and C70 Fullerenes 与C60和C70富勒烯的Lys-2His肽树状络合物的核磁共振研究

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-07-23 DOI: 10.1007/s00723-025-01776-x

Nadezhda N. Sheveleva, Irina I. Tarasenko, Maria E. Mikhailova, Irina S. Ryabokon, Viktor P. Sedov, Marina V. Suyasova, Igor M. Neelov, Denis A. Markelov

{"title":"NMR Studies of Lys-2His Peptide Dendrimers Complexes with C60 and C70 Fullerenes","authors":"Nadezhda N. Sheveleva, Irina I. Tarasenko, Maria E. Mikhailova, Irina S. Ryabokon, Viktor P. Sedov, Marina V. Suyasova, Igor M. Neelov, Denis A. Markelov","doi":"10.1007/s00723-025-01776-x","DOIUrl":"10.1007/s00723-025-01776-x","url":null,"abstract":"<div>The use of dendrimers as nanocontainers for delivering poorly soluble drugs or bioactive molecules represents one of the most promising areas of their application in biomedicine. Peptide dendrimers are considered potential candidates due to their low cytotoxicity and biodegradability. In this study, we investigated complexes of peptide dendrimers containing double histidine amino acid residues (Lys‑2His) and hydrophobic fullerenes C60 and C70 in aqueous solution experimentally by NMR methods. NMR spectroscopy and relaxation data provide evidence for the encapsulation of fullerene by the dendrimer in the Lys‑2His + C70 complex. This is due to interaction between the imidazole rings of histidine residues in the Lys-2His dendrimer and the C70 fullerene. Notably, this effect was not observed in the Lys‑2His + C60 complex. The obtained results are in good agreement with the data from atomistic molecular dynamics simulations obtained previously. These results are expected to be applicable not only for C70 fullerenes but also to various poorly water-soluble C70 derivatives, which may exhibit cytotoxic properties and biological activity. NMR spectroscopy has proven to be a powerful tool for investigating the formation and structural characteristics of complexes involving Lys‑2His dendrimers.</div>","PeriodicalId":469,"journal":{"name":"Applied Magnetic Resonance","volume":"56 8","pages":"955 - 966"},"PeriodicalIF":1.1,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144909614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Translational Diffusion of Components in Concentrated LiTFSI Solutions in Acetonitrile According to Multinuclear Pulse NMR Data 基于多核脉冲核磁共振数据的浓缩LiTFSI溶液中组分在乙腈中的平移扩散

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-07-21 DOI: 10.1007/s00723-025-01774-z

Kirill A. Mukhin, Vladimir V. Matveev, Vladimir I. Chizhik

引用次数: 0

Comparison of 10 mm and 30 mm Diameter Surface Coil Resonators for 1 GHz EPR. 1 GHz EPR中直径10 mm和30 mm表面线圈谐振器的比较。

IF 1.1 4区物理与天体物理

Applied Magnetic Resonance Pub Date : 2025-07-19 DOI: 10.1007/s00723-025-01775-y

Georgina Amassah, Tanden A Hovey, George A Rinard, Sandra S Eaton, Gareth R Eaton

{"title":"Comparison of 10 mm and 30 mm Diameter Surface Coil Resonators for 1 GHz EPR.","authors":"Georgina Amassah, Tanden A Hovey, George A Rinard, Sandra S Eaton, Gareth R Eaton","doi":"10.1007/s00723-025-01775-y","DOIUrl":"10.1007/s00723-025-01775-y","url":null,"abstract":"Two surface coil resonators were tested at 1.0 GHz as alternatives to volume resonators that fully contain the sample; a 10 mm diameter coil with Q of 61 and efficiency of 0.044 mT/√W at ~2.5 mm above the coil and a 30 mm diameter coil with Q of 56 and efficiency of 0.0038 mT/√W at ~5 mm above the coil. The 10 mm diameter coil uses power more efficiently, but the 30 mm diameter surface coil detects signal from a larger volume and the B1 extends further into the sample. The signal intensity as a function of distance from the coil was measured for small samples of lithium phthalocyanine, a 1 mm thick plate of aqueous nitroxide solution, and a 7 mm internal diameter tube containing aqueous nitroxide solution. For a sample localized at a defined distance from the coil the signal intensity can be increased by increasing incident power to compensate for the decreases in B1 with distance from the coil. However, when the noise is dominated by the source, increasing power increases noise. If incident power is adjusted to compensate for the decrease in B1 with increasing distance from the coil the S/N for aqueous nitroxide in a 1 mm thick plate, was better for the 10 mm coil than for the 30 mm coil up to about a distance of about 6 mm but that advantage is lost at greater distances from the coil. Samples of nitroxide were used as a phantom to demonstrate 3D spatial imaging with the 30 mm coil.","PeriodicalId":469,"journal":{"name":"Applied Magnetic Resonance","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12308331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144758793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0