{"title":"Lungs in Crisis: Exploring the Complexity and Management of Pulmonary Hemorrhage in Premature Neonates.","authors":"Courtney McDaniel, Samantha Mathwich, Amy J Jnah","doi":"10.1891/NN-2025-0039","DOIUrl":"10.1891/NN-2025-0039","url":null,"abstract":"<p><p>Pulmonary hemorrhage (PH) is a critical and often life-threatening condition that involves the extravasation of blood into the alveolar spaces of the lungs, resulting in impaired gas exchange and acute respiratory compromise. Very low birth weight (<1,500 g) and extremely low birth weight (ELBW; <1,000 g) infants, particularly those with underdeveloped lungs and some degree of pulmonary hypoplasia, are considered at heightened risk for PH. Among ELBW infants, PH carries an estimated mortality rate of up to 50%, underscoring its continued significance as a major contributor to neonatal morbidity and mortality. Other risk factors include a hemodynamically significant patent ductus arteriosus, surfactant administration, mechanical ventilation, and sepsis, which promote pulmonary interstitial edema and compromise alveolar integrity. This article offers neonatal clinicians a timely exploration of the current state of the science of PH, including a review of the physiology of lung and pulmonary vasculature development and treatment modalities.</p>","PeriodicalId":46706,"journal":{"name":"Neonatal Network","volume":"45 1","pages":"40-49"},"PeriodicalIF":0.7,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neonatal NetworkPub Date : 2026-02-25DOI: 10.1891/0730-0832.44.6.71
{"title":"Nursing Continuing Professional Development Activities: January/February 2026.","authors":"","doi":"10.1891/0730-0832.44.6.71","DOIUrl":"https://doi.org/10.1891/0730-0832.44.6.71","url":null,"abstract":"","PeriodicalId":46706,"journal":{"name":"Neonatal Network","volume":"45 1","pages":"71-72"},"PeriodicalIF":0.7,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Addressing Postoperative Pain for Infants in the NICU.","authors":"Tricia Vecchione, Sapna R Kudchadkar","doi":"10.1891/NN-2025-0066","DOIUrl":"https://doi.org/10.1891/NN-2025-0066","url":null,"abstract":"","PeriodicalId":46706,"journal":{"name":"Neonatal Network","volume":"45 1","pages":"7-8"},"PeriodicalIF":0.7,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evidence-Based Management of Persistent Pulmonary Hypertension.","authors":"Carol Trees","doi":"10.1891/NN-2025-0032","DOIUrl":"10.1891/NN-2025-0032","url":null,"abstract":"<p><p>Persistent pulmonary hypertension of the newborn is characterized by elevated pulmonary vascular resistance, impaired oxygenation, and delayed transition from fetal to adult circulation. Managing infants with pulmonary hypertension is particularly challenging because of the intricate and multifactorial nature of the underlying pathophysiology. A comprehensive and consistent approach to care for these critically ill infants is essential. Although numerous interventions have been extensively studied, a lack of consensus persists in clinical practice, and until recently no formal evidence-based guidelines were available. Developing a bundle of evidence-based interventions available at specific Level III NICUs may increase stabilization and decrease the need for transfer to a Level IV NICU in this high-risk population.</p>","PeriodicalId":46706,"journal":{"name":"Neonatal Network","volume":"45 1","pages":"9-17"},"PeriodicalIF":0.7,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Basics of Neonatal Herpes Simplex Virus.","authors":"Jocquelin V Jones, Megan Falke","doi":"10.1891/NN-2025-0046","DOIUrl":"10.1891/NN-2025-0046","url":null,"abstract":"<p><p>Neonatal herpes simplex virus (HSV) infection is a potentially fatal complication of maternal HSV infection, and while potentially fatal it is also entirely preventable. Although rare, the disease is associated with significant morbidity and mortality, with long-term neurologic impairment being a major concern even with current treatment advances. This review examines the epidemiology, transmission patterns, clinical manifestations, diagnosis, treatment, and prevention strategies for neonatal HSV infection. In conclusion, neonatal HSV infection represents a preventable cause of significant infant morbidity and mortality. Clinical awareness among health care providers is crucial for early recognition and prompt treatment. Prevention strategies include antiviral suppressive therapy for pregnant women with known HSV history and cesarean delivery when active lesions are present. The challenge remains in identifying asymptomatic maternal infections, as most neonatal cases occur in mothers without known HSV diagnosis.</p>","PeriodicalId":46706,"journal":{"name":"Neonatal Network","volume":"45 1","pages":"57-62"},"PeriodicalIF":0.7,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary Hypoplasia From Prolonged Prelabor Rupture of Membranes: A Case Report.","authors":"Danielle Nipper, Erin Boyle, Amy J Jnah","doi":"10.1891/NN-2025-0033","DOIUrl":"10.1891/NN-2025-0033","url":null,"abstract":"<p><p>Pulmonary hypoplasia (PH) is a rare congenital anomaly involving reduced or incomplete development of lung tissues and vasculature. Approximately 33% of pregnancies complicated by oligohydramnios are associated with PH, and upwards of 9-11/10,000 liveborn infants are diagnosed with PH each year. The estimated perinatal mortality risk is 70%. The management of affected neonates is challenging in that clinicians need to balance the need to provide adequate respiratory support in order to achieve proper ventilation-perfusion matching yet do so in the gentlest manner possible to avoid ventilator-induced lung injury and associated comorbidities. This article presents a case report of a preterm infant born with significant PH attributed to premature prelabor rupture of membranes and severe oligohydramnios, as well as a discussion of relevant physiologic, pathologic, diagnostic, and treatment data. We also emphasize the importance of multidisciplinary collaboration in optimizing prenatal counseling, parental involvement, team readiness, and coordination of care.</p>","PeriodicalId":46706,"journal":{"name":"Neonatal Network","volume":"45 1","pages":"27-39"},"PeriodicalIF":0.7,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of Crocheted Octopuses for Managing Venipuncture Pain in Preterm Infants: A Prospective Cohort Study.","authors":"Federica Buzzi, Greta Ghizzardi, Stefano Maiandi","doi":"10.1891/NN-2025-0040","DOIUrl":"10.1891/NN-2025-0040","url":null,"abstract":"<p><p>This prospective cohort study aimed to evaluate whether using a crocheted octopus reduces procedural pain during venipuncture in preterm neonates. The study compared two time-based cohorts: one receiving standard care and one receiving a nurse-led tactile intervention using a crocheted octopus. The study included 122 preterm neonates (<36 weeks' gestational age) admitted to a NICU in Iraq, with 61 infants per cohort. Procedural pain was assessed using the Premature Infant Pain Profile (PIPP) total score. Neonates in the intervention group had significantly lower PIPP scores compared with controls (mean 7.15 vs 11.67; <i>p</i> < 0.0001). No significant differences were found in gestational age or behavioral state scores. The crocheted octopus proved to be a feasible, safe, low-cost, and nurse-led intervention for managing pain in preterm neonates, particularly in resource-limited NICU settings with minimal parental involvement.</p>","PeriodicalId":46706,"journal":{"name":"Neonatal Network","volume":"45 1","pages":"50-56"},"PeriodicalIF":0.7,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neonatal NetworkPub Date : 2025-12-01DOI: 10.1891/0730-0832.44.6.435
{"title":"Nursing Continuing Professional Development Activities: November/December 2025.","authors":"","doi":"10.1891/0730-0832.44.6.435","DOIUrl":"https://doi.org/10.1891/0730-0832.44.6.435","url":null,"abstract":"","PeriodicalId":46706,"journal":{"name":"Neonatal Network","volume":"44 6","pages":"435-436"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}