Iranian Journal of Psychiatry and Behavioral Sciences最新文献

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Prediction of Cognitive Decline by Behavioral Symptoms in Neuropsychiatric Disorders 神经精神障碍患者行为症状对认知能力下降的预测
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-12-18 DOI: 10.5812/ijpbs-126596
M. Barekatain, Sona Sadeghpour, F. Rajabi, M. Maracy
{"title":"Prediction of Cognitive Decline by Behavioral Symptoms in Neuropsychiatric Disorders","authors":"M. Barekatain, Sona Sadeghpour, F. Rajabi, M. Maracy","doi":"10.5812/ijpbs-126596","DOIUrl":"https://doi.org/10.5812/ijpbs-126596","url":null,"abstract":"Background: Neuropsychiatric disorders are described by their neurological, behavioral, and cognitive symptoms. However, behavioral symptoms may often be overlooked due to the current approach in neurology. Objectives: This study investigated the relationship between behavioral symptoms and cognitive functioning in neurological disorders. The second aim was to predict neurocognitive patterns by behavioral symptoms as independent variables. Methods: Behavioral symptoms were collected based on semi-structured neuropsychiatric interviews with 211 patients admitted to the neuropsychiatry department of Ayatollah Kashani hospital in Isfahan by both a neuropsychiatry fellow and an attending neuropsychiatrist. A neuropsychiatry fellow assessed all patients using the neuropsychiatry unit cognitive (NUCog) assessment tool. We used a generalized linear model (GLM) to indicate the effect of behavioral symptoms on the risk of decline in cognitive domains. Due to the use of all available samples, this study had no age limit, and the patients were 15 to 92 years old. Results: The regression coefficient of NUCog subscale scores for behavioral symptoms using GLM revealed that education level had a positive relationship with the scores of attention (P < 0.001), visuoconstruction (P < 0.001), memory (P < 0.001), executive function (P < 0.001), language (P < 0.001), and the total score of NUCog (P < 0.001). Patients with apathy had lower scores on the memory subscale (P = 0.002) and total NUCog (P = 0.021). Similarly, patients with delusion had lower scores on memory (P = 0.006) and executive function (P = 0.026). There was a negative relationship between agitation and attention (P = 0.049), visuoconstruction (P = 0.015), memory (P = 0.018), executive function (P = 0.005), and total score of NUCog (P = 0.007). Sleep disturbances were accompanied by lower memory scores (P = 0.056) and lower mean NUCog scores (P = 0.052). Visual hallucination was associated with declined performance in attention (P = 0.057). Conclusions: Behavioral assessment can help predict cognitive patterns in patients with neurobehavioral syndromes.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43098203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Online Balint Group and Pharmacotherapy on COVID-19 Anxiety in Iranian Healthcare Workers: A Randomized Controlled Trial 在线Balint组和药物治疗对伊朗医护人员新冠肺炎焦虑的影响:一项随机对照试验
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-12-08 DOI: 10.5812/ijpbs-123763
N. Shahini, S. Gholamzad, Z. Salimi, Mansoureh Kiani Dehkordi, Saeedeh Hajebi Khaniki, Mahya Kaveh, Hossein Mohaddes Ardabili, Reza Oskoei
{"title":"Effect of Online Balint Group and Pharmacotherapy on COVID-19 Anxiety in Iranian Healthcare Workers: A Randomized Controlled Trial","authors":"N. Shahini, S. Gholamzad, Z. Salimi, Mansoureh Kiani Dehkordi, Saeedeh Hajebi Khaniki, Mahya Kaveh, Hossein Mohaddes Ardabili, Reza Oskoei","doi":"10.5812/ijpbs-123763","DOIUrl":"https://doi.org/10.5812/ijpbs-123763","url":null,"abstract":"Background: Anxiety persists following coronavirus disease 2019 (COVID-19) and has caused dysfunction. Objectives: We compared the effect of the online Balint group and pharmacotherapy on COVID-19-induced anxiety in Iranian healthcare workers (HCWs). Methods: In the current clinical trial in the north of Iran in 2021, the participants were randomly assigned to two groups, including the Balint group (eight 60-minute online sessions) and the pharmacotherapy group (sertraline), following a phone screening procedure by a psychiatrist. The groups filled out two questionnaires, namely the Connor-Davidson Resilience Scale and Corona Disease Anxiety Scale, at baseline and after the intervention (fourth week). Results: Forty-five HCWs were assessed. There was a significant difference in total anxiety score and also in sub-component in each group (P ≤ 0.001). No significant differences were observed regarding the effectiveness of both interventions in anxiety (P = 0.52); however, the pharmacotherapy interventions significantly affected the resilience and related subscales (P ≤ 0.05). The domain of spiritual influences significantly increased in the pharmacotherapy group (P = 0.031). Conclusions: Balint group and pharmacotherapy can improve COVID-19-induced anxiety and boost resilience in HCWs.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47188640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychometric Properties of the Persian Version of the 47-item Mobility Questionnaire in Children with Cerebral Palsy 波斯版47项脑瘫儿童行动能力问卷的心理测量特性
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-12-07 DOI: 10.5812/ijpbs-123340
Mansour Noori, Nazila Akbar-Fahimi, S. Hosseini, Mohsen Vahedi
{"title":"Psychometric Properties of the Persian Version of the 47-item Mobility Questionnaire in Children with Cerebral Palsy","authors":"Mansour Noori, Nazila Akbar-Fahimi, S. Hosseini, Mohsen Vahedi","doi":"10.5812/ijpbs-123340","DOIUrl":"https://doi.org/10.5812/ijpbs-123340","url":null,"abstract":"Background: Cerebral palsy (CP) is a developmental-neurological disorder that is common in children. As children with CP have several problems and limitations regarding locomotion and mobility, accessing an assessment tool for measuring mobility is crucial. Objectives: This study aims to evaluate the psychometric properties of the Persian version of the 47-item mobility questionnaire in Iranian children with cerebral palsy between 6 and 12 years of age in Tehran, Iran September 2019. Methods: In this psychometric study, 202 participants (84 girls and 118 boys, with a mean age of 95.92 months ± 23.73), 15 parents, and nine occupational therapists participated. A multistage sampling method was used. Content, construct, convergent, and face validity were estimated. Internal validity and test-retest reliability were studied, too. The convergent validity of MobQ was studied according to the gross motor functions classification scale (GMFCS). Results: The results showed that all items of the 47-item mobility questionnaire had a content validity higher than the minimum acceptable value (0.78 for CVR and 0.79 for CVI). Further, based on the opinions of 9 experts and 15 persons completing the questionnaire, an understandable and unambiguous questionnaire was reported regarding face validity. The evaluation of the intragroup correlation coefficient's reliability in this study also showed that ICC was 0.998 and Cronbach's alpha coefficient value was 0.996. A Spearman correlation coefficient of 0.937 was obtained to assess the convergent validity of the Persian version of the \"Mobility Questionnaire\" and the Gross Motor Skills Classification Scale. Conclusions: The results of this study, therefore, showed that the Persian version of the 47-item mobility questionnaire had good psychometric characteristics for children with CP between 6 and 12 years of age. Therefore, this questionnaire can be suitable for measuring children's mobility in research and clinical studies.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44544857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship between Anxiety, Resilience, and Posttraumatic Growth of the Medical Students in COVID-19 Pandemic in Iran 伊朗新冠肺炎疫情医学生焦虑、恢复力和创伤后成长的关系
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-12-06 DOI: 10.5812/ijpbs-115333
Fatemeh Ghaedi-Heidari, Fatemeh Lohrasbi, Narges Toghian, S. Samsamshariat, Farshid Rafiee Sarbijan Nasab
{"title":"The Relationship between Anxiety, Resilience, and Posttraumatic Growth of the Medical Students in COVID-19 Pandemic in Iran","authors":"Fatemeh Ghaedi-Heidari, Fatemeh Lohrasbi, Narges Toghian, S. Samsamshariat, Farshid Rafiee Sarbijan Nasab","doi":"10.5812/ijpbs-115333","DOIUrl":"https://doi.org/10.5812/ijpbs-115333","url":null,"abstract":"Background: Medical students serve as frontline individuals to COVD-19 patients, and their mental health affects the quality and safety of the provided services. Objectives: The present study aimed to identify the relationship between anxiety, resilience, and posttraumatic growth of medical interns during COVID-19 pandemic. Methods: This descriptive-correlational study was conducted in Kerman and Isfahan, Iran, from June to September 2020. The socio-demographic questionnaire, Beck Anxiety Inventory (BAI), Connor-Davidson Resilience Scale (CD-RIS), and Posttraumatic Growth Inventory (PTGI) were completed by 235 medical students. Pearson correlation test and descriptive statistics were used to analyze the data. Results: The mean and standard deviation scores of anxiety, resilience, and posttraumatic growth were 10.49, 1.08, and 50.60, as well as 13.39, 65.70, and 15.90, respectively. The results showed no significant relationship between anxiety and resilience (r = 0.16 and P = 0.057). A positive and significant correlation was observed between resilience and posttraumatic growth (r = 0.42 and P = 0.000). Furthermore, a significant negative correlation was found between anxiety and posttraumatic growth scores (r = -0.20 and P = 0.002). Conclusions: In sum, the more resilient and less anxious a person was, the greater his/her posttraumatic growth became. Therefore, it was recommended that appropriate psychological interventions be designed and implemented to improve the mental health of medical interns.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46603818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Experiences and Perspectives of Patients Treated with Methadone on Mental Health Aspect of Lifestyle: A Qualitative Study 美沙酮治疗患者生活方式心理健康方面的经验与展望:一项定性研究
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-12-06 DOI: 10.5812/ijpbs-128804
F. Amini, S. Vaziri, Z. Amini
{"title":"Experiences and Perspectives of Patients Treated with Methadone on Mental Health Aspect of Lifestyle: A Qualitative Study","authors":"F. Amini, S. Vaziri, Z. Amini","doi":"10.5812/ijpbs-128804","DOIUrl":"https://doi.org/10.5812/ijpbs-128804","url":null,"abstract":"Background: Drug abuse and its consequences place a considerable social and economic burden on society. Drug abuse has increased in Iran and reached three times the global average, indicating the need to develop innovative strategies to cope with this phenomenon. Objectives: Following a community-based participatory research approach, the aim was to identify the lived experience of drug users regarding the psychological aspect of their lifestyle. Methods: Narrative inquiry and phenomenological design were applied as the research framework. The use of in-depth interviewees and field notes guided the data collection and analysis. A total of 26 in-depth interviews were conducted with people who suffered from drug use (7 females and 19 males) in 2021. Interviewees ranging from 70 to 90 minutes were conducted in a quiet, private location chosen by the researcher. All interviews were audio-taped and transcribed, and analyzed using Colaizzi's method. Data analysis was administered using MAXQDA version 2020. Results: Most of the participants were educated Diploma and above. The participants' age ranged from 25 to 53 years old. During the interview, the subjects were in the following stages, methadone treatment time (n = 26). The analysis revealed four themes, and 11 sub-themes emerged. The themes were as follows: (1) negative emotions; (2) poor psychological capital; (3) poor support; and (4) psychological well-being. Conclusions: The most important problems of people with substance use, in the psychological dimension of lifestyle, include experiencing negative emotions, weak psychological capital, weak social support, unhealthy psychological well-being such as negative self-acceptance, reduced positive relations, not having a purposeful life, and inability to control environmental pressures. Hopefully, this study can help health policymakers develop more effective strategies against drug use.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46145634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Evaluation of Uncivil Behaviors in Clinical Learning Environments from the Perspective of Nursing Students in Western Iran in 2020 2020年伊朗西部地区护生临床学习环境不文明行为评价
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-12-06 DOI: 10.5812/ijpbs-120945
M. Shohani, Mahboobeh Rasouli, A. Nasrollahi
{"title":"An Evaluation of Uncivil Behaviors in Clinical Learning Environments from the Perspective of Nursing Students in Western Iran in 2020","authors":"M. Shohani, Mahboobeh Rasouli, A. Nasrollahi","doi":"10.5812/ijpbs-120945","DOIUrl":"https://doi.org/10.5812/ijpbs-120945","url":null,"abstract":"Background: Uncivil behavior in clinical learning environments is a growing challenge that severely disrupts the teaching and learning process. Objectives: The aim of this study is to evaluate the incidence of uncivil behavior in clinical learning environments from the perspective of nursing students in western Iran. Methods: In this self-report descriptive cross-sectional study in the 2020 year, 135 undergraduate nursing students of semesters 3, 4, 6, and 8, who were taking training and internship courses, were enrolled. The standard UBCNE questionnaire with 20 questions based on the Likert scale and subscales of exclusionary, hostile/rude, and dismissive behaviors constituted research tools. Data were analyzed using SPSS version 21 and descriptive and inferential statistics. Results: 103 (76.3%) trainees and 32 (23.7%) interns with a mean age of 21.53 years (1.60) participated in this study. According to the results of the Kruskal-Wallis test, the mean scores of hostile/rude, exclusionary, and dismissive behaviors and the total score in different semesters were significantly different (P < 0.001). In terms of the semester, these behaviors had the highest rate in semester 6 students and the lowest in semester 8 students. There was no statistically significant relationship between gender and the mean incidence of these behaviors in students. Conclusions: The results show the students’ experience with different behaviors in clinical settings according to different contexts. Further research is required to understand these behaviors in clinical settings better and to provide strategies to minimize such behaviors.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46624536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facilitators and Barriers to Child Sexual Abuse Interventions: A Qualitative Study of Interventions in Iran 儿童性虐待干预的推动者和障碍:伊朗干预的定性研究
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-11-23 DOI: 10.5812/ijpbs-129326
Morteza Danaeifar, M. Arshi, Amir Moghanibashi-Mansourieh, Leila Ostadhashemi
{"title":"Facilitators and Barriers to Child Sexual Abuse Interventions: A Qualitative Study of Interventions in Iran","authors":"Morteza Danaeifar, M. Arshi, Amir Moghanibashi-Mansourieh, Leila Ostadhashemi","doi":"10.5812/ijpbs-129326","DOIUrl":"https://doi.org/10.5812/ijpbs-129326","url":null,"abstract":"Background: Child sexual abuse is a public health problem in most countries. Sensitization, research, and programs for identifying and preventing child sexual abuse have been carried out at the national level with increased political and social awareness and international commitments to decline its consequences. Objectives: This study investigated the facilitators and barriers to community-based interventions for child sexual abuse. Methods: Semi-structured interviews were conducted between September 2021 and March 2022 with 15 purposefully selected experts. The interviews were audio-recorded, transcribed, and analyzed using the content analysis method. Results: Several barriers and facilitators affected child sexual abuse interventions. The barriers included: (1) sociocultural challenges; (2) legal challenges and gaps; and (3) managerial-structural challenges, while the facilitators were: (1) the improvement of the quality of provided services; and (2) facilitative role of the law. Conclusions: Social interventions for child sexual abuse could consider some items to improve implementation, namely as follow: (1) the intersectional cooperation of organizations and beneficiaries to conduct child abuse interventions for children and their families at the local and national levels; (2) the implementation of empowerment activities for the return of children and parents to the community after child sexual abuse; and (3) the revision of the laws and establishment of more deterrent punishments.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47048346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparison of Antenatal Maternal Mental Representations Between Depressed and Non-depressed of Pregnant Mothers 抑郁孕妇与非抑郁孕妇产前心理表征的比较
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-11-23 DOI: 10.5812/ijpbs-129589
R. Amini, Shima Shakiba, M. Afrakhteh, Masoumeh Pourmohammadreza Tajrishi, Mohammad Moradi
{"title":"Comparison of Antenatal Maternal Mental Representations Between Depressed and Non-depressed of Pregnant Mothers","authors":"R. Amini, Shima Shakiba, M. Afrakhteh, Masoumeh Pourmohammadreza Tajrishi, Mohammad Moradi","doi":"10.5812/ijpbs-129589","DOIUrl":"https://doi.org/10.5812/ijpbs-129589","url":null,"abstract":"Background: Depression is the most prevalent mental health problem in the pregnant women with significant implications for mother and infant’s health. The content of maternal antenatal representations may be related to their depressive symptoms during the perinatal period. Objectives: This study aimed to compare maternal mental representations between depressed and non-depressed groups of pregnant women. Methods: In a causal-comparative study, participants were selected using an inverse stratified sampling method among pregnant women in the last trimester of pregnancy (depressed mothers = 93, and non-depressed mothers = 97). All participants completed Edinburgh Postnatal Depression Scale (EPDS), Dépistage Anténatal de la Dépression Postnatale (DADP), and semi-structure Interview-R after the consent form. Independent- samples t-test, Two-way ANOVA, and Pearson correlation coefficient were applied to compare maternal mental representations subscales between groups, using SPSS-26. Results: The results showed significantly fewer positive ratings for all subscales of Interview-R, including child, partner, self as mother, and mother as own mother in the depressed group (P < 0.05). In the group of depressed mothers, 57% and 32% of the correlations among the representations of child/self as mother and child/partner were significant, while in the non-depressed group, 28% and 48% of the correlations between child/self as mother and child/ partner were significant (P < 0,05), respectively. The characteristics of self as mother and own mother showed significant differences in the depressed group compared to the non-depressed group (P < 0.05). Conclusions: Depressed pregnant mothers are less likely to differentiate themselves from their children compared to non-depressed pregnant mothers. Besids, depressed pregnant mothers perceive themselves as mothers more positively than their own mothers, while the opposite is true for non-depressed pregnant mothers.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48451844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Transcranial Direct Current Stimulation in Behavioral and Cognitive Aspects of Executive Function in Children with Autism Spectrum Disorder 经颅直流电刺激对自闭症谱系障碍儿童执行功能行为和认知方面的影响
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-11-05 DOI: 10.5812/ijpbs-124236
M. Amiri, Samaneh Karamali Esmaili, Shafagh Saei, Mehdi Alizadeh Zarei
{"title":"Effectiveness of Transcranial Direct Current Stimulation in Behavioral and Cognitive Aspects of Executive Function in Children with Autism Spectrum Disorder","authors":"M. Amiri, Samaneh Karamali Esmaili, Shafagh Saei, Mehdi Alizadeh Zarei","doi":"10.5812/ijpbs-124236","DOIUrl":"https://doi.org/10.5812/ijpbs-124236","url":null,"abstract":"Background: Despite their high effectiveness, rehabilitation therapies can reduce the number of families with children with autism spectrum disorder (ASD) visiting clinics due to the number of treatment sessions and the long duration of treatment. The use of technological methods, such as transcranial direct current stimulation (tDCS) as one of the therapeutic interventions to improve cognitive function in rehabilitation clinics, can help reduce the duration of treatment for these children. Objectives: The present study was carried out to examine the effectiveness of tDCS in behavioral and cognitive aspects of executive functions in children with ASD. Methods: A pretest and posttest design with follow-up were used in this study. The subjects were children with high-functioning ASD aged 8 - 11 years who were selected by the convenience sampling method from occupational therapy clinics in Tehran, Iran. A total of 20 eligible candidates were included in the study according to inclusion and exclusion criteria. The subjects were randomly divided into two groups (10 subjects in each group). The intervention group received tDCS during 12 sessions of 20 minutes in the dorsolateral prefrontal cortex area, with an electrode size of 35 cm2 for 3 weeks (four sessions per week). The control group received common cognitive interventions used in occupational therapy clinics in 12 sessions of 60 minutes (one hour) for 6 weeks (two sessions per week). Follow-up was performed one month after the end of the interventions. The research instruments included the Behavior Rating Inventory of Executive Function and computer-based tests, such as the Tower of London, Wisconsin Card Sorting Test, and Stroop test. Results: The results demonstrated that tDCS, similar to cognitive rehabilitation, could affect the cognitive functions of the brain, such as executive functions, and several basic cognitive processes, such as inhibitory control, cognitive flexibility, and mental planning. Conclusions: The findings recommended using tDCS as a new intervention method to improve the cognitive function of individuals with ASD. This is due to the lasting effect of the results of this intervention as a technological instrument with faster results than other clinical interventions.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48702205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Study of STin2 (intron 2) Variant of the SLC6A4 Gene in Children and Adolescents with Attention-deficit Hyperactivity Disorder 儿童和青少年注意缺陷多动障碍SLC6A4基因STin2(内含子2)变体的分子研究
IF 1
Iranian Journal of Psychiatry and Behavioral Sciences Pub Date : 2022-11-02 DOI: 10.5812/ijpbs-122884
S. Amiri, Mahan Asadian, M. Shekari Khaniani, Sima Mansouri Derakhshan, Negar Pourhossein Rahmani, A. Shafiee-Kandjani, Leila Mehdizadeh Fanid
{"title":"Molecular Study of STin2 (intron 2) Variant of the SLC6A4 Gene in Children and Adolescents with Attention-deficit Hyperactivity Disorder","authors":"S. Amiri, Mahan Asadian, M. Shekari Khaniani, Sima Mansouri Derakhshan, Negar Pourhossein Rahmani, A. Shafiee-Kandjani, Leila Mehdizadeh Fanid","doi":"10.5812/ijpbs-122884","DOIUrl":"https://doi.org/10.5812/ijpbs-122884","url":null,"abstract":"Background: Attention-deficit hyperactivity disorder (ADHD) is one of the most familiar childhood psychiatric disorders. Various molecular genetic reviews indicate that genes are crucial in susceptibility to ADHD. The serotonin transporter gene (SLC6A4) has polymorphisms that correlate with ADHD. The association between ADHD and SLC6A4 gene variants in the Iranian population has not been investigated yet. Objectives: This study analyzed the STin2 (intron 2) variant of the SLC6A4 gene in Iranian children and adolescents with ADHD. Methods: In this retrospective case-control study, 86 ADHD patients and 99 healthy volunteers aged five to 14 were enrolled as the case and control groups, respectively. The STin2 (intron2) fragment of the SLC6A4 gene was amplified using specific primers by conventional PCR, and three STin2 alleles of the SLC6A4 gene (STin2.9, STin2.10, and STin2.12) were examined using the acrylamide gel method. Results: We found no significant difference between the ADHD and control groups in STin2.9 (34.9% vs. 39.4%, P-value = 0.824), STin2.10 (29.1% vs. 23.2%, P-value = 1.354), and STin2.12 (36% vs. 36.4%, P-value = 0.986) variants. Conclusions: There was no association between the frequency of STin2 variant alleles of the SLC6A4 gene and ADHD, but in the study of risk estimation, allele 10 of this variant was a risk allele in ADHD patients.","PeriodicalId":46644,"journal":{"name":"Iranian Journal of Psychiatry and Behavioral Sciences","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44393643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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