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Learning points about myalgic encephalomyelitis/chronic fatigue syndrome: Bridging the gap between research, clinical practice and awareness. 有关肌痛性脑炎/慢性疲劳综合征的学习要点：弥合研究、临床实践和认识之间的差距。
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-05-27 DOI: 10.1177/14782715241257968
Bhanu Wahi-Singh
{"title":"Learning points about myalgic encephalomyelitis/chronic fatigue syndrome: Bridging the gap between research, clinical practice and awareness.","authors":"Bhanu Wahi-Singh","doi":"10.1177/14782715241257968","DOIUrl":"10.1177/14782715241257968","url":null,"abstract":"<p><p>This essay examines the complex landscape of myalgic encephalomyelitis, commonly known as chronic fatigue syndrome, highlighting its chronic and multisystemic nature with elusive causative factors. It discusses clinical challenges in diagnosis and management, emphasising the importance of increased education and awareness among healthcare professionals. The role of empathic, person-centred care in improving patient outcomes is underscored, urging for a paradigm shift towards understanding and addressing the profound impact of myalgic encephalitis/chronic fatigue syndrome on patients' lives.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"168-169"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pseudomesothelioma due to squamous cell lung cancer: An uncommon occurrence. 鳞状细胞肺癌引起的假性脂肪瘤：不常见的病例
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-05-30 DOI: 10.1177/14782715241258502
Brandon Sze Mann Tan, Graeme Penman Currie, Andrea Chapman, Senthil Ragupathy, David Robert Miller
{"title":"Pseudomesothelioma due to squamous cell lung cancer: An uncommon occurrence.","authors":"Brandon Sze Mann Tan, Graeme Penman Currie, Andrea Chapman, Senthil Ragupathy, David Robert Miller","doi":"10.1177/14782715241258502","DOIUrl":"10.1177/14782715241258502","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"182-183"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Existing and emerging GLP-1 receptor agonist therapy: Ramifications for diabetic retinopathy screening. 现有和新兴的 GLP-1 受体激动剂疗法：对糖尿病视网膜病变筛查的影响。
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-04-05 DOI: 10.1177/14782715241244843
George Iype Varughese, Sarita Jacob
{"title":"Existing and emerging GLP-1 receptor agonist therapy: Ramifications for diabetic retinopathy screening.","authors":"George Iype Varughese, Sarita Jacob","doi":"10.1177/14782715241244843","DOIUrl":"10.1177/14782715241244843","url":null,"abstract":"<p><p>GLP-1 receptor agonist treatment revolutionised the management of type 2 diabetes mellitus with significant enhancement of cardiovascular risk reduction. They have been instrumental in effectively managing the glycaemic control of this at-risk patient group. This class of drugs are associated with rapid improvement in glucose levels and consequently, transient early worsening of <i>pre-existing diabetic retinopathy</i> (DR) which is well-recognised, but this paradox is less commonly perceived in routine clinical practice. The recent shortage of supply has resulted in an enforced hiatus to prescribing all existing GLP-1 receptor agonists, which is expected to last all through 2024. This becomes even more pertinent as their DR could have progressed due to worsening HbA1c as a result of the unforeseen interruption to GLP-1 receptor agonist treatment. Therefore, when these medications are recommenced in a few months' time, all prescribers need to be aware of these patients' most up-to-date DR status and liaise with their affiliated screening service.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"170-173"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-flow carotid cavernous fistula and 'white eye': A rare and easily misdiagnosed presentation - A case report and literature review. 高流量颈动脉海绵瘘和 "白眼"：罕见且易误诊的表现--病例报告和文献综述。
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-04-18 DOI: 10.1177/14782715241246572
Francisco Caiza-Zambrano, Martín Gómez Lastra, Silvia Garbugino, Fabio Maximiliano Gonzalez, Julio Galarza Menoscal, Mauricio Benetti, Yemina Neme Segura, Luis Ariel Miquelini, Claudia Uribe-Roca, Manuel Fernández-Pardal, Luciana León-Cejas, Ricardo Reisin, Pablo Bonardo
{"title":"High-flow carotid cavernous fistula and 'white eye': A rare and easily misdiagnosed presentation - A case report and literature review.","authors":"Francisco Caiza-Zambrano, Martín Gómez Lastra, Silvia Garbugino, Fabio Maximiliano Gonzalez, Julio Galarza Menoscal, Mauricio Benetti, Yemina Neme Segura, Luis Ariel Miquelini, Claudia Uribe-Roca, Manuel Fernández-Pardal, Luciana León-Cejas, Ricardo Reisin, Pablo Bonardo","doi":"10.1177/14782715241246572","DOIUrl":"10.1177/14782715241246572","url":null,"abstract":"<p><p>The three classic symptoms of carotid cavernous fistula (CCF) are pulsating exophthalmos, bruit and conjunctival chemosis. Here, we present a clinical case of isolated abducens nerve palsy due to a high-flow CCF in an 84-year-old woman, without the typical congestive orbito-ocular features. It was a diagnostic challenge because, for patients older than 50 years with cardiovascular risk factors, ischaemic mononeuropathy is the most frequent aetiology. This case illustrates the least common type of CCF that can be easily misdiagnosed. Physicians should consider fistula as a possible diagnosis in a patient with isolated abducens nerve palsy even without the classic triad.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"144-148"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140860728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guillain Barre syndrome mimicking brain death. 模仿脑死亡的格林巴利综合征
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-04-04 DOI: 10.1177/14782715241244839
Mukesh Kumar Sarna, Sarthak Shah, Puneet Rijhwani, Gourav Goyal, Anand Kumar Jain, Pallaavi Goel
{"title":"Guillain Barre syndrome mimicking brain death.","authors":"Mukesh Kumar Sarna, Sarthak Shah, Puneet Rijhwani, Gourav Goyal, Anand Kumar Jain, Pallaavi Goel","doi":"10.1177/14782715241244839","DOIUrl":"10.1177/14782715241244839","url":null,"abstract":"<p><p>A 49-year-old female patient presented at the hospital with a history of herpetic blisters, frequent episodes of vomiting and loose stools, bilateral upper and lower limb weakness, and diminishing sensorium. She was diagnosed with hyponatraemia and respiratory failure and later became unconscious with absent brainstem reflexes. The patient was initially treated for herpetic encephalitis, a chronic obstructive pulmonary disease with acute exacerbation, hyponatraemia and neuroparalytic snake bite. Further evaluation, however, identified the uncommon Guillain Barre syndrome presentation with overlap of Bickerstaff brainstem encephalitis. This is an uncommon disorder characterised by the involvement of higher mental functions, fixed dilated pupils, absent brainstem reflexes and quadriplegia that resembles a neuroparalytic snake bite and brain death. After receiving intravenous immunoglobulins for treatment, the patient completely recovered.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"138-143"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intensive glucose control and the clinical paradox of transient progression of diabetic retinopathy: Prioritising the relevance of eye screening intervals. 强化血糖控制与糖尿病视网膜病变短暂进展的临床悖论：优先考虑眼科筛查间隔的相关性。
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-05-15 DOI: 10.1177/14782715241254873
Sarita Jacob, George I Varughese
{"title":"Intensive glucose control and the clinical paradox of transient progression of diabetic retinopathy: Prioritising the relevance of eye screening intervals.","authors":"Sarita Jacob, George I Varughese","doi":"10.1177/14782715241254873","DOIUrl":"10.1177/14782715241254873","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"180-181"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140922634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dr George Jamieson Ross McHardy BM, BCh, FRCPE, FRCP. 乔治-贾米森-罗斯-麦克哈迪博士（Dr. George Jamieson Ross McHardy BM, BCh, FRCPE, FRCP）。
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-05-30 DOI: 10.1177/14782715241259058
Anthony Seaton
{"title":"Dr George Jamieson Ross McHardy BM, BCh, FRCPE, FRCP.","authors":"Anthony Seaton","doi":"10.1177/14782715241259058","DOIUrl":"10.1177/14782715241259058","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"186-187"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Informed consent in clinical practice: Old problems, new challenges. 临床实践中的知情同意：老问题，新挑战。
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-04-14 DOI: 10.1177/14782715241247087
Isaac Ks Ng
{"title":"Informed consent in clinical practice: Old problems, new challenges.","authors":"Isaac Ks Ng","doi":"10.1177/14782715241247087","DOIUrl":"10.1177/14782715241247087","url":null,"abstract":"<p><p>Informed consent is a fundamental tenet of patient-centred clinical practice as it upholds the ethical principle of patient autonomy and promotes shared decision-making. In the medicolegal realm, failure to meet the accepted standards of consent can be considered as medical negligence which has both legal and professional implications. In general, valid consent requires three core components: (1) the presence of mental capacity - characterised by the patient's ability to comprehend, retain information, weigh options and communicate the decision, (2) adequate information disclosure - based on the 'reasonable physician' or 'reasonable patient' standards and (3) voluntariness in decision-making. Nonetheless, in real-world clinical settings, informed consent is not always optimally achieved, due to various patient, contextual and systemic factors. In this article, I herein discuss three major challenges to informed consent in clinical practice: (1) patient literacy and sociocultural factors, (2) psychiatric illnesses and elderly patients with cognitive impairment and (3) artificial intelligence in clinical care, and sought to offer practical mitigating strategies to address these barriers.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"153-158"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140857731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical students highlight the importance of medical education, kindness, compassion and belief when learning about patients with myalgic encephalomyelitis/chronic fatigue syndrome. 医科学生在了解肌痛性脑脊髓炎/慢性疲劳综合征患者时，强调了医学教育、仁慈、同情和信念的重要性。
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-05-27 DOI: 10.1177/14782715241255977
Nina Louise Muirhead
{"title":"Medical students highlight the importance of medical education, kindness, compassion and belief when learning about patients with myalgic encephalomyelitis/chronic fatigue syndrome.","authors":"Nina Louise Muirhead","doi":"10.1177/14782715241255977","DOIUrl":"10.1177/14782715241255977","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"118-119"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Was thalidomide a placebo hypnotic? 沙利度胺是安慰剂催眠药吗？
IF 1.1
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2024-06-01 Epub Date: 2024-05-28 DOI: 10.1177/14782715241258503
Stewart Justman
{"title":"Was thalidomide a placebo hypnotic?","authors":"Stewart Justman","doi":"10.1177/14782715241258503","DOIUrl":"10.1177/14782715241258503","url":null,"abstract":"<p><p>Six decades ago the world learned that thalidomide, a seemingly non-toxic sedative and hypnotic, caused severe birth defects including the flipper-like deformity of the arms known as phocomelia. When thalidomide was tested against placebo by the trialist Louis Lasagna in 1960 (while the drug was banned from the U.S. marketplace), he found the 100-mg dosage equivalent to placebo, as well as greatly inferior to the 200-mg dosage, in producing sleep. Even as these findings were made known, a 100-mg dose of thalidomide was in general use as a sleep aid for pregnant women. It appears that unbeknownst to themselves, an untold number of pregnant women around the world who were prescribed thalidomide incurred the risks of a teratogen in return for the benefits of a sugar pill.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":" ","pages":"161-164"},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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