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Journal of the Royal College of Physicians of Edinburgh最新文献

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Ludwig's angina in a patient with ulcerative colitis on thiopurine therapy. 一例溃疡性结肠炎患者的Ludwig心绞痛接受硫嘌呤治疗。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-09-26 DOI: 10.1177/14782715231200503
Amit Yadav, Harshavardhan Telaprolu, Sourabha K Patro, Ujjwal Gorsi, Vishal Sharma
{"title":"Ludwig's angina in a patient with ulcerative colitis on thiopurine therapy.","authors":"Amit Yadav, Harshavardhan Telaprolu, Sourabha K Patro, Ujjwal Gorsi, Vishal Sharma","doi":"10.1177/14782715231200503","DOIUrl":"10.1177/14782715231200503","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41153937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sinus tachycardia and long-COVID: An opportunity in the challenge. 窦性心动过速和长covid:挑战中的机遇。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-11-22 DOI: 10.1177/14782715231213896
Abdallah Al-Mohammad, Andreas L Kyriacou
{"title":"Sinus tachycardia and long-COVID: An opportunity in the challenge.","authors":"Abdallah Al-Mohammad, Andreas L Kyriacou","doi":"10.1177/14782715231213896","DOIUrl":"10.1177/14782715231213896","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138292052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Moral distress in healthcare professionals: Time to reflect. 医疗保健专业人员的道德困境:是时候反思了。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-11-24 DOI: 10.1177/14782715231215409
Graeme P Currie, Robert Bs Laing
{"title":"Moral distress in healthcare professionals: Time to reflect.","authors":"Graeme P Currie, Robert Bs Laing","doi":"10.1177/14782715231215409","DOIUrl":"10.1177/14782715231215409","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The evolution of ScotRIGHT: The first pan-Scotland physician trainee research network. ScotRIGHT 的演变：首个泛苏格兰实习医生研究网络。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-08-31 DOI: 10.1177/14782715231197240
Victoria El Moffat, Paul N Brennan, Daniel R Gaya, Peter C Hayes, Shahida Din
{"title":"The evolution of ScotRIGHT: The first pan-Scotland physician trainee research network.","authors":"Victoria El Moffat, Paul N Brennan, Daniel R Gaya, Peter C Hayes, Shahida Din","doi":"10.1177/14782715231197240","DOIUrl":"10.1177/14782715231197240","url":null,"abstract":"<p><p>Scotland has a distinguished track record in foundational clinical research. From the completion of the first clinical trial undertaken in scurvy to cloning the world's first whole mammal, Scottish basic and clinical research is world leading. More recently, challenges in access to research skills, funding and programmes by clinical trainees led to the development of alternatives to these typical avenues of accessing research opportunities. Trainee networks evolved to meet the needs of trainees looking to access projects and collaboratives beyond audit and quality improvement commonly performed during structured training. These networks have enjoyed enormous success and have succeeded in progressing projects which have impactful outputs for patients, and improving clinical services. Here, we describe the foundation of the first pan-Scotland physician trainee research network; Scottish Trainees Research In Gastroterology and Hepatology (ScotRIGHT). We outline the foundational efforts, requisites and foundations required to develop a research network.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10124534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of Lemierre's syndrome causing panhypopituitarism, cavernous sinus thrombosis, ischaemic stroke and pulmonary embolism. 一例导致泛垂体功能减退、海绵窦血栓形成、缺血性中风和肺栓塞的莱米埃尔综合征病例。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-09-07 DOI: 10.1177/14782715231198180
Charlotte J Dewdney, Joseph J Anderson, Simon Dewar, Fergus Doubal, Frederick R Burgess, Deepak Subedi, Marcus J Lyall
{"title":"A case of Lemierre's syndrome causing panhypopituitarism, cavernous sinus thrombosis, ischaemic stroke and pulmonary embolism.","authors":"Charlotte J Dewdney, Joseph J Anderson, Simon Dewar, Fergus Doubal, Frederick R Burgess, Deepak Subedi, Marcus J Lyall","doi":"10.1177/14782715231198180","DOIUrl":"10.1177/14782715231198180","url":null,"abstract":"<p><p>Infection is a rare cause of panhypopituitarism and has not been reported in the context of Lemierre's syndrome. We present the case of a previously well 19-year-old man, who presented acutely unwell with meningitis and sepsis. <i>Fusobacterium necrophorum</i> was isolated from peripheral blood cultures and identified on cerebrospinal fluid with 16S rDNA Polymerase Chain Reaction (PCR). Imaging demonstrated internal jugular vein thrombosis with subsequent cavernous venous sinus thrombosis. Pituitary function tests were suggestive of panhypopituitarism. The patient was diagnosed with Lemierre's syndrome complicated by meningitis, cavernous sinus thrombosis, base of skull osteomyelitis, ischaemic stroke and panhypopituitarism. He was treated with 13 weeks of intravenous antibiotics followed by 3 weeks of oral amoxicillin, and anticoagulated with dalteparin then apixaban. His panhypopituitarism was managed with hydrocortisone, levothyroxine and desmopressin.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10170420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carriage of multidrug-resistant carbapenemase-producing gram-negative bacteria in patients admitted to NHS Greater Glasgow and Clyde hospitals: Implications for treatment. NHS大格拉斯哥和克莱德医院患者携带耐多药碳青霉烯酶产生的革兰氏阴性菌：对治疗的影响。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-10-17 DOI: 10.1177/14782715231205919
Megan Espie, Aleksandra Marek, Leonard Farrugia, Mairi MacLeod, Abhijit M Bal
{"title":"Carriage of multidrug-resistant carbapenemase-producing gram-negative bacteria in patients admitted to NHS Greater Glasgow and Clyde hospitals: Implications for treatment.","authors":"Megan Espie, Aleksandra Marek, Leonard Farrugia, Mairi MacLeod, Abhijit M Bal","doi":"10.1177/14782715231205919","DOIUrl":"10.1177/14782715231205919","url":null,"abstract":"<p><strong>Background: </strong>Infections caused by gram-negative carbapenemase-producing organisms (CPO) have become a global phenomenon. Screening of patients for CPO that was carried out at 48-h intervals enables early detection of carriers for infection control purposes and planning therapy.</p><p><strong>Methods: </strong>We investigated the bacterial flora detected on screening, the enzymes that conferred resistance and the proportion of patients who developed bacteraemia with CPO and their therapy.</p><p><strong>Results: </strong>In all, 27 patients had a positive screen for CPO. A small but significant (7.5%) proportion of patients were not detected on initial screening. <i>Escherichia coli</i> and <i>Klebsiella</i> were predominant. New-Delhi metallo β-lactamase and oxacillin carbapenemases were the main enzymatic mechanisms of resistance. Four (14.8%) patients developed bacteraemia with CPO (30- and 90-day survival 100% and 75%, respectively).</p><p><strong>Conclusion: </strong>A single negative screen does not rule out colonisation. A significant proportion of patients colonised with CPO develop bacteraemia. Vigilance is needed to prevent the nosocomial spread of CPO.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19? Let me see your hands. 2019冠状病毒疾病让我看看你的手。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-10-18 DOI: 10.1177/14782715231206530
David Bernal-Bello, Celia Lara-Montes, Beatriz Jaenes-Barrios
{"title":"COVID-19? Let me see your hands.","authors":"David Bernal-Bello, Celia Lara-Montes, Beatriz Jaenes-Barrios","doi":"10.1177/14782715231206530","DOIUrl":"10.1177/14782715231206530","url":null,"abstract":"<p><p>During the first wave of the COVID�19 pandemic, a patient with anti-synthetase syndrome (ASS) was misdiagnosed as having bilateral severe acute respiratory syndrome coronavirus 2 pneumonia on admission. A comprehensive clinical evaluation would have led to the correct diagnosis earlier, as he had some data consistent with ASS on both physical examination and laboratory tests that were initially overlooked. In addition, a malignant lesion in the colon was found on screening for underlying malignancy. In this context, ASS has been considered a low-risk subgroup for cancer among idiopathic inflammatory myopathies. However, this should be interpreted cautiously and should not lead to neglect of adequate cancer screening adjusted for age, sex and other potential risk factors.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiation proctitis with recurrent gastrointestinal bleeding complicated by cytomegalovirus. 放射性直肠炎伴复发性胃肠道出血并发巨细胞病毒。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-10-31 DOI: 10.1177/14782715231205916
Austin B Auyeung, Melanie N Rayan, Xiaolan Tang, Sanil Thomas
{"title":"Radiation proctitis with recurrent gastrointestinal bleeding complicated by cytomegalovirus.","authors":"Austin B Auyeung, Melanie N Rayan, Xiaolan Tang, Sanil Thomas","doi":"10.1177/14782715231205916","DOIUrl":"10.1177/14782715231205916","url":null,"abstract":"<p><p>Cytomegalovirus (CMV) usually causes infections with mild symptoms in immunocompetent individuals. However, in immunocompromised patients, these infections can be serious or life-threatening. Following initial infection, CMV typically becomes dormant but remains lifelong in the host. Reactivation of the latent virus can occur in many organ systems, including the gastrointestinal (GI) tract. Radiation proctitis is a known risk factor associated with prostate radiation, with complicating ulceration and GI bleeding. We present the first case report of an immunocompetent 81-year-old male with multiple episodes of life-threatening GI bleeding, secondary to a non-healing CMV-positive rectal ulcer and CMV colitis following radiation for prostate cancer. Multiple insults including prostate radiation, repeated blood transfusions and CMV infection likely contributed to the recurrent bleeding episodes.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71414666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adrenocorticotropic hormone-secreting phaeochromocytoma as a cause of treatment-resistant hypertension and recurrent pulmonary emboli. 分泌促肾上腺皮质激素的嗜铬细胞瘤是导致顽固性高血压和复发性肺栓塞的原因。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI: 10.1177/14782715231210605
Shobitha Vollmer, Henrik Borg
{"title":"Adrenocorticotropic hormone-secreting phaeochromocytoma as a cause of treatment-resistant hypertension and recurrent pulmonary emboli.","authors":"Shobitha Vollmer, Henrik Borg","doi":"10.1177/14782715231210605","DOIUrl":"10.1177/14782715231210605","url":null,"abstract":"<p><p>We report an unusual case of a patient presenting with Cushing's syndrome caused by a phaeochromocytoma secreting adrenocorticotropic hormone (ACTH). The patient had a history of treatment-resistant hypertension, secondary amenorrhoea and tendency towards hypokalaemia. She had multiple signs of Cushing's syndrome, such as swelling, bruising, abdominal striae and proximal myopathy. Hypokalaemia is more common in patients with ectopic ACTH-secretion than other causes of Cushing's syndrome. Computed tomography, adrenal vein sampling and biochemistry could confirm an ACTH-secreting phaeochromocytoma. It is important to consider that hypersecretion of more than one hormone may exist in a unilateral adrenal adenoma. This patient also presented with recurrent pulmonary emboli, and there is an increased risk of venous thromboembolism in patients with ACTH-secreting phaeochromocytoma. Anticoagulation should be considered for as long as the disease is active. We demonstrate that unilateral adrenalectomy can be curative in patients with ACTH-secreting phaeochromocytoma.</p>","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resuscitation resolutions. 复苏决议。
IF 1.4
Journal of the Royal College of Physicians of Edinburgh Pub Date : 2023-12-01 Epub Date: 2023-11-07 DOI: 10.1177/14782715231210016
Clare Bostock
{"title":"Resuscitation resolutions.","authors":"Clare Bostock","doi":"10.1177/14782715231210016","DOIUrl":"10.1177/14782715231210016","url":null,"abstract":"","PeriodicalId":46606,"journal":{"name":"Journal of the Royal College of Physicians of Edinburgh","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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